| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
2
|
D7CC07_STRBB (D7CC07) |
|
(5 hsp) |
0.0 |
3705 |
49% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-1
SBI_01381
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
3
|
Q8CJN6_STRCO (Q8CJN6) |
|
(6 hsp) |
0.0 |
3489 |
52% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCO6275
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] |
|
5
|
D7BRD4_STRBB (D7BRD4) |
|
(17 hsp) |
0.0 |
3455 |
51% |
|
- Product
- Short-chain dehydrogenase/reductase SDR
- Gene
- SBI_01976
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
9
|
C3VLY1_9ACTO (C3VLY1) |
|
(10 hsp) |
0.0 |
3246 |
48% |
|
- Product
- Polyketide synthase type I
- Gene
- mlaA1
- Organism
- Streptomyces sp. MP39-85
|
1uniprot[Pubmed] 19854930 Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010] |
|
10
|
Q0R4M8_STRAT (Q0R4M8) |
|
(8 hsp) |
0.0 |
3243 |
49% |
|
- Product
- ChlA1
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
11
|
C3VLV4_9ACTO (C3VLV4) |
|
(9 hsp) |
0.0 |
3237 |
47% |
|
- Product
- Polyketide synthase type I
- Gene
- becA
- Organism
- Streptomyces sp. DSM 21069
|
1uniprot[Pubmed] 19875084 Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009] |
|
12
|
A4FCY9_SACEN (A4FCY9) |
|
(5 hsp) |
0.0 |
3201 |
48% |
|
- Product
- Modular polyketide synthase
- Gene
- SACE_2630
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
14
|
Q93HE5_STRAW (Q93HE5) |
|
(8 hsp) |
0.0 |
3117 |
47% |
|
- Product
- Modular polyketide synthase
Putative modular polyketide synthase
- Gene
- pks5
SAV2368 SAV_2368
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 12692562 [Medline] 22608306 Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003] | [pubmed all]
|
15
|
B3TMQ8_9ACTO (B3TMQ8) |
|
(9 hsp) |
0.0 |
3052 |
48% |
|
- Product
- Polyketide synthase
- Gene
- KijS1
- Organism
- Actinomadura kijaniata
|
1uniprot[Pubmed] 17985890 Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007] |
|
16
|
F4F8H7_VERMA (F4F8H7) |
|
(7 hsp) |
0.0 |
3031 |
49% |
|
- Product
- Beta-ketoacyl synthase
- Gene
- VAB18032_17090
- Organism
- Verrucosispora maris (strain AB-18-032)
|
1uniprot[Pubmed] 21551311 Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011] |
|
17
|
A4FH85_SACEN (A4FH85) |
|
(10 hsp) |
0.0 |
2995 |
51% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4141
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
18
|
Q5VKQ3_SACER (Q5VKQ3) |
|
(10 hsp) |
0.0 |
2995 |
51% |
|
- Product
- Type I PKS
- Gene
- pkeAI
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
19
|
Q6JHN8_9PSEU (Q6JHN8) |
|
(9 hsp) |
0.0 |
2992 |
47% |
|
- Product
- ObsA
- Gene
-
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 15346767 Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004] |
|
22
|
D7CC08_STRBB (D7CC08) |
|
(11 hsp) |
0.0 |
2976 |
50% |
|
- Product
- Putative type I polyketide synthase
- Gene
- pks5-2
SBI_01382
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
25
|
B1W4J1_STRGG (B1W4J1) |
|
(6 hsp) |
0.0 |
2898 |
47% |
|
- Product
- Putative type-I PKS
- Gene
- pks2-1
SGR_6179
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
27
|
C6ZCS1_9ACTO (C6ZCS1) |
|
(18 hsp) |
0.0 |
2863 |
48% |
|
- Product
- Type I modular polyketide synthase
- Gene
- ttnA
- Organism
- Streptomyces griseochromogenes
|
1uniprot[Pubmed] 19191560 Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009] |
|
28
|
A4KCE4_9ACTO (A4KCE4) |
|
(18 hsp) |
0.0 |
2853 |
48% |
|
- Product
- Tautomycetin biosynthetic PKS
- Gene
-
- Organism
- Streptomyces sp. CK4412
|
1uniprot[Pubmed] 17379718 Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007] |
|
29
|
B5L6K8_MICCH (B5L6K8) |
|
(9 hsp) |
0.0 |
2852 |
45% |
|
- Product
- Putative type I polyketide synthase
- Gene
-
- Organism
- Micromonospora chalcea
|
1uniprot[Pubmed] 18586939 Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008] |
|
30
|
A0ACH3_STRAM (A0ACH3) |
|
(10 hsp) |
0.0 |
2844 |
50% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SAMR0467
- Organism
- Streptomyces ambofaciens ATCC 23877
|
1uniprot[Pubmed] 16956972 Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006] | 2uniprot Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006] |
|
32
|
Q0QMQ1_9ACTO (Q0QMQ1) |
|
(10 hsp) |
0.0 |
2801 |
49% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aculeolatus
|
1uniprot[Pubmed] 16724457 Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.(J. Antibiot.) [2006] |
|
33
|
Q0RIF5_FRAAA (Q0RIF5) |
|
(7 hsp) |
0.0 |
2801 |
47% |
|
- Product
- Putative type I polyketide synthase
- Gene
- FRAAL4072
- Organism
- Frankia alni (strain ACN14a)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
34
|
Q0QMN7_9ACTO (Q0QMN7) |
|
(10 hsp) |
0.0 |
2800 |
50% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces sp. Eco86
|
1uniprot[Pubmed] 16724457 Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.(J. Antibiot.) [2006] |
|
36
|
Q7WTF1_9ACTO (Q7WTF1) |
|
(5 hsp) |
0.0 |
2778 |
45% |
|
- Product
- NanA5
- Gene
- nanA5
- Organism
- Streptomyces nanchangensis
|
1uniprot[Pubmed] 12770825 [Medline] 22654646 A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003] |
|
39
|
D7BSN6_STRBB (D7BSN6) |
|
(5 hsp) |
0.0 |
2768 |
45% |
|
- Product
- Modular polyketide synthase
- Gene
- nanA5
SBI_08415
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
40
|
D7C2B8_STRBB (D7C2B8) |
|
(16 hsp) |
0.0 |
2766 |
52% |
|
- Product
- Type I modular polyketide synthase
- Gene
- pks3-2
SBI_00651
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
41
|
Q93NW6_9ACTO (Q93NW6) |
|
(20 hsp) |
0.0 |
2758 |
52% |
|
- Product
- AmphC
- Gene
- amphC
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
43
|
Q30CS0_STRAU (Q30CS0) |
|
(6 hsp) |
0.0 |
2738 |
51% |
|
- Product
- LipPks3
- Gene
- lipPks3
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
44
|
Q82QT4_STRAW (Q82QT4) |
|
(17 hsp) |
0.0 |
2737 |
52% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
SAV419 SAV_419
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
45
|
Q52V50_9ACTO (Q52V50) |
|
(13 hsp) |
0.0 |
2729 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
46
|
Q52V53_9ACTO (Q52V53) |
|
(12 hsp) |
0.0 |
2725 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
47
|
Q54299_STRHY (Q54299) |
|
(12 hsp) |
0.0 |
2722 |
46% |
|
- Product
- Polyketide synthase
- Gene
- rapC
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 7644502 [Medline] 95372374 The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995] | 2uniprot[Pubmed] 8635730 [Medline] 96186895 Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996] | 3uniprot[Pubmed] 8635756 [Medline] 96186896 Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996] | [pubmed all]
|
48
|
B6CLY8_9MYCO (B6CLY8) |
|
(24 hsp) |
0.0 |
2712 |
43% |
|
- Product
- Type I modular polyketide synthase, MlsA1
- Gene
- mlsA1
MULP_065
- Organism
- Mycobacterium liflandii 128FXT
|
1uniprot[Pubmed] 18840298 Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008] |
|
49
|
Q6MZA4_MYCUA (Q6MZA4) |
|
(24 hsp) |
0.0 |
2710 |
43% |
|
- Product
- Type I modular polyketide synthase
- Gene
- mlsA1
MUP040c
- Organism
- Mycobacterium ulcerans (strain Agy99)
|
1uniprot[Pubmed] 15758215 Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005] | 2uniprot[Pubmed] 14736915 Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004] | [pubmed all]
|
50
|
Q93H87_STRAW (Q93H87) |
|
(14 hsp) |
0.0 |
2705 |
51% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA1
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
51
|
F8QZS1_STRCX (F8QZS1) |
|
(7 hsp) |
0.0 |
2696 |
46% |
|
- Product
- Polyketide synthase
- Gene
- SchA5
- Organism
- Streptomyces chartreusis
|
1uniprot[Pubmed] 21173184 Characterization of the biosynthesis gene cluster for the pyrrole polyether antibiotic calcimycin (A23187) in Streptomyces chartreusis NRRL 3882.(Antimicrob. Agents Chemother.) [2011] |
|
53
|
D3U9Y6_9ACTO (D3U9Y6) |
|
(10 hsp) |
0.0 |
2692 |
48% |
|
- Product
- Type I polyketide synthase
- Gene
- sfaF
- Organism
- Streptomyces flaveolus
|
1uniprot Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010] |
|
54
|
F1CLC1_9ACTO (F1CLC1) |
|
(14 hsp) |
0.0 |
2685 |
51% |
|
- Product
- ScnS1
- Gene
- scnS1
- Organism
- Streptomyces chattanoogensis
|
1uniprot[Pubmed] 21330439 The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011] |
|
55
|
C5HV15_STRAT (C5HV15) |
|
(7 hsp) |
0.0 |
2668 |
51% |
|
- Product
- Polyketide synthase
- Gene
- idmM
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
57
|
Q9L4W3_9ACTO (Q9L4W3) |
|
(18 hsp) |
0.0 |
2667 |
51% |
|
- Product
- NysC
- Gene
- nysC
- Organism
- Streptomyces noursei
|
1uniprot[Pubmed] 10873841 [Medline] 20334850 Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000] |
|
59
|
Q9X993_9ACTO (Q9X993) |
|
(14 hsp) |
0.0 |
2651 |
51% |
|
- Product
- PimS1 protein
Polyketide synthase
- Gene
- pimS1
- Organism
- Streptomyces natalensis
|
1uniprot[Pubmed] 10187796 [Medline] 99214571 The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999] | 2uniprot[Pubmed] 11094342 [Medline] 20547809 A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000] | [pubmed all]
|
60
|
Q52V52_9ACTO (Q52V52) |
|
(11 hsp) |
0.0 |
2649 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
62
|
Q9ALM2_9PSEU (Q9ALM2) |
|
(9 hsp) |
0.0 |
2635 |
49% |
|
- Product
- Polyketide synthase extender modules 8-10
- Gene
- spnE
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 11358695 [Medline] 21257765 Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001] |
|
63
|
A1YAN0_AMYOR (A1YAN0) |
|
(10 hsp) |
0.0 |
2634 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
64
|
Q6W5Q0_9ACTO (Q6W5Q0) |
|
(19 hsp) |
0.0 |
2628 |
52% |
|
- Product
- FscC
- Gene
- fscC
- Organism
- Streptomyces sp. FR-008
|
1uniprot[Pubmed] 14652074 Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003] |
|
67
|
Q54296_STRHY (Q54296) |
|
(17 hsp) |
0.0 |
2623 |
45% |
|
- Product
- Polyketide synthase
- Gene
- rapB
- Organism
- Streptomyces hygroscopicus
|
1uniprot[Pubmed] 7644502 [Medline] 95372374 The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995] | 2uniprot[Pubmed] 8635730 [Medline] 96186895 Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996] | 3uniprot[Pubmed] 8635756 [Medline] 96186896 Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996] | [pubmed all]
|
68
|
Q52V49_9ACTO (Q52V49) |
|
(6 hsp) |
0.0 |
2620 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Streptomyces aizunensis
|
1uniprot[Pubmed] 15844935 Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005] |
|
69
|
D2CKM4_PSEAH (D2CKM4) |
|
(18 hsp) |
0.0 |
2619 |
52% |
|
- Product
- CppC
- Gene
- cppC
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 19697072 Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009] |
|
70
|
C6WNV0_ACTMD (C6WNV0) |
|
(9 hsp) |
0.0 |
2615 |
51% |
|
- Product
- Short-chain dehydrogenase/reductase SDR
- Gene
- Amir_2684
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
73
|
C6WN16_ACTMD (C6WN16) |
|
(12 hsp) |
0.0 |
2569 |
51% |
|
- Product
- Mycocerosate synthase., Erythronolide synthase
- Gene
- Amir_4699
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
76
|
A1YAM7_AMYOR (A1YAM7) |
|
(10 hsp) |
0.0 |
2538 |
51% |
|
- Product
- Polyketide synthase type I
- Gene
-
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 17136886 Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006] |
|
77
|
C6WNW1_ACTMD (C6WNW1) |
|
(13 hsp) |
0.0 |
2537 |
50% |
|
- Product
- Short-chain dehydrogenase/reductase SDR
- Gene
- Amir_2695
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
78
|
Q76KY0_STRHA (Q76KY0) |
|
(10 hsp) |
0.0 |
2526 |
49% |
|
- Product
- Polyketide synthase modules 1-3
- Gene
- vinP1
- Organism
- Streptomyces halstedii
|
1uniprot[Pubmed] 15112997 Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004] |
|
79
|
Q6JHN6_9PSEU (Q6JHN6) |
|
(13 hsp) |
0.0 |
2525 |
50% |
|
- Product
- ObsC
- Gene
-
- Organism
- Saccharopolyspora spinosa
|
1uniprot[Pubmed] 15346767 Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004] |
|
81
|
Q0R4M5_STRAT (Q0R4M5) |
|
(11 hsp) |
0.0 |
2519 |
47% |
|
- Product
- ChlA3
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
85
|
Q82QT5_STRAW (Q82QT5) |
|
(7 hsp) |
0.0 |
2504 |
50% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA2
SAV418 SAV_418
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
86
|
D7BRE0_STRBB (D7BRE0) |
|
(9 hsp) |
0.0 |
2500 |
51% |
|
- Product
- Modular polyketide synthase
- Gene
- SBI_01982
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
88
|
B5L6K9_MICCH (B5L6K9) |
|
(13 hsp) |
0.0 |
2497 |
48% |
|
- Product
- Putative type I polyketide synthase
- Gene
-
- Organism
- Micromonospora chalcea
|
1uniprot[Pubmed] 18586939 Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008] |
|
89
|
D3U9Y8_9ACTO (D3U9Y8) |
|
(17 hsp) |
0.0 |
2494 |
51% |
|
- Product
- Type I polyketide synthase
- Gene
- sfaH
- Organism
- Streptomyces flaveolus
|
1uniprot Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010] |
|
90
|
Q93H86_STRAW (Q93H86) |
|
(7 hsp) |
0.0 |
2493 |
50% |
|
- Product
- Modular polyketide synthase
- Gene
- pteA2
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
91
|
Q93NX8_9ACTO (Q93NX8) |
|
(10 hsp) |
0.0 |
2491 |
50% |
|
- Product
- AmphJ
- Gene
- amphJ
- Organism
- Streptomyces nodosus
|
1uniprot[Pubmed] 11451671 [Medline] 21344785 Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001] | 2uniprot[Pubmed] 16079135 Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005] | [pubmed all]
|
92
|
B6ZIR2_STRPT (B6ZIR2) |
|
(15 hsp) |
0.0 |
2491 |
48% |
|
- Product
- Polyketide synthase
- Gene
- pldAI
- Organism
- Streptomyces platensis
|
1uniprot[Pubmed] 18997414 Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008] |
|
93
|
Q9EX53_STRCO (Q9EX53) |
|
(8 hsp) |
0.0 |
2486 |
48% |
|
- Product
- Putative type I polyketide synthase
- Gene
- SCO6274
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] |
|
94
|
A4FH84_SACEN (A4FH84) |
|
(7 hsp) |
0.0 |
2485 |
50% |
|
- Product
- Type I modular polyketide synthase
- Gene
- SACE_4140
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
95
|
Q5VKQ8_SACER (Q5VKQ8) |
|
(7 hsp) |
0.0 |
2485 |
50% |
|
- Product
- Type I PKS
- Gene
- pkeAII
- Organism
- Saccharopolyspora erythraea
Streptomyces erythraeus
|
1uniprot[Pubmed] 15925898 A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004] |
|
96
|
C5HV16_STRAT (C5HV16) |
|
(10 hsp) |
0.0 |
2481 |
49% |
|
- Product
- Polyketide synthase
- Gene
- idmN
- Organism
- Streptomyces antibioticus
|
1uniprot Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009] |
|
97
|
Q0R4M7_STRAT (Q0R4M7) |
|
(8 hsp) |
0.0 |
2474 |
47% |
|
- Product
- ChlA2
- Gene
-
- Organism
- Streptomyces antibioticus
|
1uniprot[Pubmed] 16793515 Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006] |
|
98
|
Q30CR9_STRAU (Q30CR9) |
|
(9 hsp) |
0.0 |
2472 |
53% |
|
- Product
- LipPks4
- Gene
- lipPks4
- Organism
- Streptomyces aureofaciens
|
1uniprot[Pubmed] 16723573 Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006] |
|
99
|
C3VLZ4_9ACTO (C3VLZ4) |
|
(7 hsp) |
0.0 |
2463 |
49% |
|
- Product
- Polyketide synthase type I
- Gene
- mlaD
- Organism
- Streptomyces sp. MP39-85
|
1uniprot[Pubmed] 19854930 Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010] |
|