BLAST table : Ansam_00280

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q8KUH4_ACTPA
(Q8KUH4)		 
[query] 1 - 3073 (3073)
[subject] 1 - 3073 (3073)
 0.0 5775   100% Polyketide synthase asmB Actinosynnema pretiosum subsp. auranticum
2
 C6W8L0_ACTMD
(C6W8L0)		 
[query] 564 - 3072 (3073)
[subject] 617 - 3147 (3148)
 0.0 4180   94% Acyl transferase Amir_3198 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
3
 B4VDY6_9ACTO
(B4VDY6)		 
[query] 29 - 2629 (3073)
[subject] 19 - 2637 (4894)
(6 hsp)		 0.0 2162   51% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
4
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 1 - 2629 (3073)
[subject] 1 - 2666 (5588)
(7 hsp)		 0.0 2133   49% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
5
 D6AIT5_STRFL
(D6AIT5)		 
[query] 26 - 2629 (3073)
[subject] 1061 - 3659 (5541)
(9 hsp)		 0.0 2131   51% Rifamycin polyketide synthase SSGG_00427 Streptomyces roseosporus NRRL 15998
6
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 2 - 2629 (3073)
[subject] 5 - 2521 (3377)
(4 hsp)		 0.0 2129   50% Polyketide synthase type I becF Streptomyces sp. DSM 21069
7
 Q30CR9_STRAU
(Q30CR9)		 Jump to Alip_00160 
[query] 2 - 2629 (3073)
[subject] 3 - 2632 (3277)
(5 hsp)		 0.0 2126   49% LipPks4 lipPks4 Streptomyces aureofaciens
8
 A4X8L0_SALTO
(A4X8L0)		 
[query] 29 - 2629 (3073)
[subject] 3643 - 6278 (7210)
(11 hsp)		 0.0 2125   50% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
9
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 8 - 2629 (3073)
[subject] 21 - 2519 (3373)
(5 hsp)		 0.0 2125   50% Polyketide synthase type I mlaF Streptomyces sp. MP39-85
10
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 29 - 2629 (3073)
[subject] 3599 - 6201 (7110)
(11 hsp)		 0.0 2124   51% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
11
 Q82QT4_STRAW
(Q82QT4)		 
[query] 23 - 2629 (3073)
[subject] 4280 - 6826 (7746)
(16 hsp)		 0.0 2124   50% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
12
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 29 - 2629 (3073)
[subject] 1776 - 4406 (5321)
(6 hsp)		 0.0 2120   50% Polyketide synthase natC Streptomyces sp. CS
13
 Q0R4M8_STRAT
(Q0R4M8)		 Jump to Chth_00260 
[query] 3 - 2629 (3073)
[subject] 1055 - 3765 (4699)
(8 hsp)		 0.0 2119   50% ChlA1 Streptomyces antibioticus
14
 D9WQL2_9ACTO
(D9WQL2)		 
[query] 5 - 2633 (3073)
[subject] 6 - 2496 (3284)
(4 hsp)		 0.0 2108   50% Modular polyketide synthase SSOG_07859 Streptomyces himastatinicus ATCC 53653
15
 E8WEN9_STRFA
(E8WEN9)		 
[query] 2 - 2629 (3073)
[subject] 3 - 2611 (3511)
(4 hsp)		 0.0 2104   50% Mycocerosate synthase, 6-deoxyerythronolide-B synthase Sfla_0983 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD) 2.3.1.111

2.3.1.94
16
 Q52V49_9ACTO
(Q52V49)		 
[query] 7 - 2629 (3073)
[subject] 9 - 2672 (3872)
(5 hsp)		 0.0 2102   49% Polyketide synthase type I Streptomyces aizunensis
17
 Q0S8W4_RHOSR
(Q0S8W4)		 
[query] 1 - 2632 (3073)
[subject] 1 - 2631 (3527)
(5 hsp)		 0.0 2101   49% Type I polyketide synthase RHA1_ro04231 Rhodococcus sp. (strain RHA1)
18
 C1B9P9_RHOOB
(C1B9P9)		 
[query] 1 - 2632 (3073)
[subject] 1 - 2633 (3527)
(6 hsp)		 0.0 2101   48% Polyketide synthase ROP_41550 Rhodococcus opacus (strain B4)
19
 D9WQ64_9ACTO
(D9WQ64)		 
[query] 23 - 2629 (3073)
[subject] 990 - 3635 (3874)
(7 hsp)		 0.0 2099   48% Modular polyketide synthase SSOG_05738 Streptomyces himastatinicus ATCC 53653
20
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 18 - 2630 (3073)
[subject] 552 - 3154 (10827)
(18 hsp)		 0.0 2096   50% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
21
 F1CT52_9ACTO
(F1CT52)		 
[query] 1 - 2629 (3073)
[subject] 1 - 2683 (3418)
(5 hsp)		 0.0 2092   47% GdmAII gdmAII Streptomyces autolyticus
22
 C9YYI2_STRSW
(C9YYI2)		 
[query] 29 - 2629 (3073)
[subject] 38 - 2682 (3919)
(5 hsp)		 0.0 2087   50% Putative type I polyketide synthase SCAB_83911 Streptomyces scabies (strain 87.22)
Streptomyces scabiei
23
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 29 - 2632 (3073)
[subject] 3768 - 6361 (7488)
(9 hsp)		 0.0 2086   51% ObsC Saccharopolyspora spinosa
24
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 29 - 2629 (3073)
[subject] 1786 - 4409 (5339)
(7 hsp)		 0.0 2085   49% Polyketide synthase natB Streptomyces sp. CS
25
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 1 - 2629 (3073)
[subject] 5 - 2669 (4928)
(9 hsp)		 0.0 2084   49% Polyketide synthase extender modules 5-7 spnD Saccharopolyspora spinosa
26
 A8LUX2_SALAI
(A8LUX2)		 
[query] 27 - 2632 (3073)
[subject] 2664 - 5201 (7279)
(14 hsp)		 0.0 2083   50% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
27
 D8HZ82_AMYMU
(D8HZ82)		 
[query] 29 - 2629 (3073)
[subject] 632 - 3054 (4735)
(11 hsp)		 0.0 2082   51% Rifamycin polyketide synthase rifA
AMED_0617		 Amycolatopsis mediterranei (strain U-32)
28
 O54666_AMYMD
(O54666)		 Jump to Rifam_00210 
[query] 29 - 2629 (3073)
[subject] 632 - 3054 (4735)
(11 hsp)		 0.0 2082   51% RifA
Rifamycin polyketide synthase, type 1		 rifA Amycolatopsis mediterranei
Nocardia mediterranei
29
 E0KBI2_STRVO
(E0KBI2)		 
[query] 29 - 2629 (3073)
[subject] 33 - 2640 (4930)
(7 hsp)		 0.0 2082   49% Mycocerosate synthase., 6-deoxyerythronolide-B synthase StrviDRAFT_0197 Streptomyces violaceusniger Tu 4113 2.3.1.111

2.3.1.94
30
 Q1WEK9_9ACTO
(Q1WEK9)		 
[query] 29 - 2629 (3073)
[subject] 2523 - 5049 (5712)
(11 hsp)		 0.0 2079   51% Polyketide synthase merA Streptomyces sp. NRRL 30748
31
 D7F1M1_9ACTO
(D7F1M1)		 
[query] 29 - 2558 (3073)
[subject] 2094 - 4641 (5630)
(8 hsp)		 0.0 2075   48% Polyketide synthase tsnAIII Streptomyces longisporoflavus
32
 C3VLZ4_9ACTO
(C3VLZ4)		 
[query] 5 - 2637 (3073)
[subject] 6 - 2493 (3365)
(4 hsp)		 0.0 2075   50% Polyketide synthase type I mlaD Streptomyces sp. MP39-85
33
 D9VBL5_9ACTO
(D9VBL5)		 
[query] 31 - 2629 (3073)
[subject] 984 - 3492 (5113)
(12 hsp)		 0.0 2073   50% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
34
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 29 - 2631 (3073)
[subject] 1578 - 4202 (6831)
(10 hsp)		 0.0 2071   49% ScnS1 scnS1 Streptomyces chattanoogensis
35
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 29 - 2630 (3073)
[subject] 1723 - 4280 (5176)
(7 hsp)		 0.0 2071   50% ObsB Saccharopolyspora spinosa
36
 F1ADM0_9ACTO
(F1ADM0)		 
[query] 1 - 2629 (3073)
[subject] 1 - 2716 (3968)
(6 hsp)		 0.0 2068   49% BafAIII Streptomyces lohii
37
 E0KBI0_STRVO
(E0KBI0)		 
[query] 2 - 2637 (3073)
[subject] 5 - 2666 (3955)
(6 hsp)		 0.0 2063   48% Acyl transferase StrviDRAFT_0195 Streptomyces violaceusniger Tu 4113
38
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 4 - 2629 (3073)
[subject] 5 - 2573 (5060)
(8 hsp)		 0.0 2062   49% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
39
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 4 - 2629 (3073)
[subject] 5 - 2573 (5060)
(8 hsp)		 0.0 2061   49% Rifamycin polyketide synthase rifB
AMED_0618		 Amycolatopsis mediterranei (strain U-32)
40
 A8M6C6_SALAI
(A8M6C6)		 
[query] 29 - 2629 (3073)
[subject] 638 - 3182 (5154)
(10 hsp)		 0.0 2060   50% AMP-dependent synthetase and ligase Sare_1246 Salinispora arenicola (strain CNS-205)
41
 Q3S863_9ACTO
(Q3S863)		 Jump to Conca_00070 
[query] 16 - 2627 (3073)
[subject] 24 - 2671 (3982)
(6 hsp)		 0.0 2060   49% Modular polyketide synthase Streptomyces neyagawaensis
42
 E8S0C5_MICSL
(E8S0C5)		 
[query] 5 - 2630 (3073)
[subject] 5071 - 7720 (9937)
(15 hsp)		 0.0 2059   49% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
43
 D9W5N3_9ACTO
(D9W5N3)		 
[query] 29 - 2637 (3073)
[subject] 603 - 3229 (4488)
(9 hsp)		 0.0 2058   50% Lasalocid modular polyketide synthase SSNG_07463 Streptomyces sp. C
44
 O52789_AMYMD
(O52789)		 
[query] 4 - 2629 (3073)
[subject] 14 - 2582 (5069)
(8 hsp)		 0.0 2056   49% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
45
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 23 - 2631 (3073)
[subject] 1556 - 4170 (6797)
(11 hsp)		 0.0 2055   49% PimS1 protein
Polyketide synthase		 pimS1 Streptomyces natalensis
46
 A0FCL1_STRVO
(A0FCL1)		 Jump to Merid_00020 
[query] 29 - 2629 (3073)
[subject] 2531 - 5051 (5721)
(11 hsp)		 0.0 2050   52% MerA merA Streptomyces violaceoniger
47
 F8QPG1_9ACTO
(F8QPG1)		 
[query] 1 - 2629 (3073)
[subject] 1 - 2681 (3621)
(5 hsp)		 0.0 2048   49% Polyketide synthase natD Streptomyces sp. CS
48
 D9XDI5_STRVR
(D9XDI5)		 
[query] 29 - 2635 (3073)
[subject] 34 - 2671 (2922)
(3 hsp)		 0.0 2048   50% Type I polyketide synthase SSQG_00882 Streptomyces viridochromogenes DSM 40736
49
 D9T6W4_MICAI
(D9T6W4)		 
[query] 5 - 2630 (3073)
[subject] 5071 - 7719 (9936)
(15 hsp)		 0.0 2044   49% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
50
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 24 - 2636 (3073)
[subject] 1677 - 4189 (5099)
(6 hsp)		 0.0 2043   50% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
51
 C3VLW6_9ACTO
(C3VLW6)		 
[query] 5 - 2637 (3073)
[subject] 6 - 2499 (3372)
(4 hsp)		 0.0 2042   50% Polyketide synthase type I becD Streptomyces sp. DSM 21069
52
 D7BRD4_STRBB
(D7BRD4)		 
[query] 35 - 2634 (3073)
[subject] 4604 - 7224 (9950)
(17 hsp)		 0.0 2040   50% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
53
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 3 - 2747 (3073)
[subject] 5 - 2714 (3596)
(4 hsp)		 0.0 2037   48% Polyketide synthase idmM Streptomyces antibioticus
54
 Q0QMN7_9ACTO
(Q0QMN7)		 
[query] 28 - 2668 (3073)
[subject] 1063 - 3682 (4290)
(8 hsp)		 0.0 2032   51% Polyketide synthase type I Streptomyces sp. Eco86
55
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 29 - 2631 (3073)
[subject] 1762 - 4373 (10917)
(16 hsp)		 0.0 2028   48% AmphC amphC Streptomyces nodosus
56
 A4FH85_SACEN
(A4FH85)		 
[query] 29 - 2629 (3073)
[subject] 1018 - 3608 (4327)
(8 hsp)		 0.0 2024   50% Type I modular polyketide synthase SACE_4141 Saccharopolyspora erythraea (strain NRRL 23338)
57
 Q5VKQ3_SACER
(Q5VKQ3)		 
[query] 29 - 2629 (3073)
[subject] 1018 - 3608 (4327)
(8 hsp)		 0.0 2024   50% Type I PKS pkeAI Saccharopolyspora erythraea
Streptomyces erythraeus
58
 Q9EX53_STRCO
(Q9EX53)		 
[query] 4 - 2629 (3073)
[subject] 8 - 2671 (3576)
(5 hsp)		 0.0 2020   46% Putative type I polyketide synthase SCO6274 Streptomyces coelicolor
59
 F1DI33_9ACTO
(F1DI33)		 
[query] 4 - 2680 (3073)
[subject] 5 - 2686 (2801)
(4 hsp)		 0.0 2017   48% TrdAIII Streptomyces sp. SCSIO1666
60
 A8M6C7_SALAI
(A8M6C7)		 
[query] 5 - 2629 (3073)
[subject] 6 - 2627 (5255)
(6 hsp)		 0.0 2014   48% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
61
 Q76KZ3_STRHA
(Q76KZ3)		 Jump to Vicen_00070 
[query] 1 - 2629 (3073)
[subject] 1 - 2638 (3808)
(4 hsp)		 0.0 2013   49% Polyketide synthase modules 7-8 vinP4 Streptomyces halstedii
62
 E0D206_9ACTO
(E0D206)		 Jump to FD891_00050 
[query] 1 - 2649 (3073)
[subject] 1 - 2657 (3799)
(4 hsp)		 0.0 2012   49% Polyketide synthase gfsE Streptomyces graminofaciens
63
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 22 - 2636 (3073)
[subject] 1015 - 3644 (6241)
(11 hsp)		 0.0 2011   50% Polyketide synthase KijS1 Actinomadura kijaniata
64
 D3Y1I5_9ACTO
(D3Y1I5)		 
[query] 4 - 2680 (3073)
[subject] 5 - 2686 (2801)
(4 hsp)		 0.0 2006   47% TamAIII Streptomyces sp. 307-9
65
 F8JVX1_STRCT
(F8JVX1)		 
[query] 23 - 2630 (3073)
[subject] 2816 - 5400 (6125)
(11 hsp)		 0.0 2006   48% Putative 6-methylsalicylic acid synthase SCAT_0136 Streptomyces cattleya 2.3.1.165

2.3.1.94
66
 A1YAM7_AMYOR
(A1YAM7)		 
[query] 2 - 2629 (3073)
[subject] 10 - 2494 (5723)
(8 hsp)		 0.0 2006   49% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
67
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 2 - 2629 (3073)
[subject] 3 - 2650 (5066)
(5 hsp)		 0.0 2003   48% Putative polyketide synthase rubB Streptomyces achromogenes subsp. rubradiris
68
 B4VBW0_9ACTO
(B4VBW0)		 
[query] 29 - 2629 (3073)
[subject] 6548 - 9198 (10873)
(19 hsp)		 0.0 2002   48% Polyketide synthase type I SSAG_05337 Streptomyces sp. Mg1
69
 Q93HE5_STRAW
(Q93HE5)		 
[query] 25 - 2629 (3073)
[subject] 971 - 3658 (4498)
(7 hsp)		 0.0 2000   48% Modular polyketide synthase
Putative modular polyketide synthase		 pks5
SAV2368
SAV_2368		 Streptomyces avermitilis
70
 D1XUK5_9ACTO
(D1XUK5)		 
[query] 29 - 2631 (3073)
[subject] 1717 - 4254 (5157)
(9 hsp)		 0.0 1999   50% Short-chain dehydrogenase/reductase SDR SACTEDRAFT_6365 Streptomyces sp. SA3_actE
71
 Q1MX73_9ACTO
(Q1MX73)		 Jump to Tetrn_00160 
[query] 29 - 2629 (3073)
[subject] 2114 - 4740 (5657)
(9 hsp)		 0.0 1999   46% Type I polyketide synthase tmnAIV Streptomyces sp. NRRL 11266
72
 B5A9Q0_9PSEU
(B5A9Q0)		 
[query] 1 - 2629 (3073)
[subject] 25 - 2641 (3401)
(4 hsp)		 0.0 1998   50% MbcAII mbcAII Actinosynnema pretiosum subsp. pretiosum
73
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 21 - 2633 (3073)
[subject] 7308 - 9925 (10876)
(13 hsp)		 0.0 1993   50% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
74
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 27 - 2635 (3073)
[subject] 1024 - 3670 (6383)
(10 hsp)		 0.0 1992   45% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
75
 Q846X2_STRCM
(Q846X2)		 Jump to Monen_00190 
[query] 1 - 2636 (3073)
[subject] 1 - 2755 (4106)
(5 hsp)		 0.0 1991   47% Monensin polyketide synthase modules 7 and 8 monAV Streptomyces cinnamonensis
76
 C6W8V0_ACTMD
(C6W8V0)		 
[query] 1 - 2629 (3073)
[subject] 1 - 2617 (3408)
(4 hsp)		 0.0 1991   50% Acyl transferase Amir_3293 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
77
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 1 - 2629 (3073)
[subject] 6 - 2586 (5400)
(6 hsp)		 0.0 1990   49% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
78
 D9VEY7_9ACTO
(D9VEY7)		 
[query] 29 - 2635 (3073)
[subject] 1827 - 4422 (5260)
(8 hsp)		 0.0 1990   47% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
79
 Q0ILC7_9ACTO
(Q0ILC7)		 
[query] 1 - 2759 (3073)
[subject] 1 - 2754 (3897)
(5 hsp)		 0.0 1989   47% NlmA4 nlmA4 Streptomyces nanchangensis
80
 F8QPF8_9ACTO
(F8QPF8)		 
[query] 19 - 2688 (3073)
[subject] 1053 - 3701 (5698)
(9 hsp)		 0.0 1988   49% Polyketide synthase natA Streptomyces sp. CS
81
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 2 - 2637 (3073)
[subject] 3 - 2784 (5532)
(7 hsp)		 0.0 1987   48% Type I polyketide synthase AVES 3 aveA3
SAV942
SAV_942		 Streptomyces avermitilis
82
 E8WEN5_STRFA
(E8WEN5)		 
[query] 29 - 2629 (3073)
[subject] 1719 - 4252 (5156)
(6 hsp)		 0.0 1987   50% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
83
 D7F1M0_9ACTO
(D7F1M0)		 
[query] 1 - 2558 (3073)
[subject] 3 - 2573 (5136)
(9 hsp)		 0.0 1985   47% Polyketide synthase tsnAII Streptomyces longisporoflavus
84
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 2 - 2633 (3073)
[subject] 3 - 2632 (11096)
(16 hsp)		 0.0 1979   48% NysC nysC Streptomyces noursei
85
 D8HZ86_AMYMU
(D8HZ86)		 
[query] 1 - 2629 (3073)
[subject] 1 - 2565 (3413)
(5 hsp)		 0.0 1979   49% Rifamycin polyketide synthase rifE
AMED_0621		 Amycolatopsis mediterranei (strain U-32)
86
 O54593_AMYMD
(O54593)		 Jump to Rifam_00250 
[query] 1 - 2629 (3073)
[subject] 1 - 2565 (3413)
(5 hsp)		 0.0 1979   49% RifE
Rifamycin polyketide synthase, type 1		 rifE Amycolatopsis mediterranei
Nocardia mediterranei
87
 Q1L0S8_STRHY
(Q1L0S8)		 
[query] 7 - 2637 (3073)
[subject] 1063 - 3676 (5683)
(10 hsp)		 0.0 1978   48% NapA Streptomyces hygroscopicus subsp. duamyceticus
88
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 27 - 2634 (3073)
[subject] 4118 - 6689 (7620)
(12 hsp)		 0.0 1978   48% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
89
 A4X8M0_SALTO
(A4X8M0)		 
[query] 1 - 2629 (3073)
[subject] 1 - 2584 (3711)
(6 hsp)		 0.0 1976   49% Beta-ketoacyl synthase Strop_2778 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
90
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 1 - 2646 (3073)
[subject] 1 - 2626 (7102)
(11 hsp)		 0.0 1976   48% Polyketide synthase merB Streptomyces sp. NRRL 30748
91
 A4X8M3_SALTO
(A4X8M3)		 
[query] 1 - 2629 (3073)
[subject] 1 - 2556 (3463)
(4 hsp)		 0.0 1976   49% Beta-ketoacyl synthase Strop_2781 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
92
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 27 - 2634 (3073)
[subject] 4075 - 6645 (7576)
(12 hsp)		 0.0 1974   48% Type I modular polyketide synthase ttnB Streptomyces griseochromogenes
93
 Q2PC83_STRAH
(Q2PC83)		 Jump to Rubra_00070 
[query] 29 - 2629 (3073)
[subject] 1003 - 3587 (5349)
(10 hsp)		 0.0 1971   48% Putative polyketide synthase rubA Streptomyces achromogenes subsp. rubradiris
94
 D9WG07_9ACTO
(D9WG07)		 
[query] 29 - 2629 (3073)
[subject] 269 - 2898 (3668)
(6 hsp)		 0.0 1971   49% Modular polyketide synthase SSOG_02937 Streptomyces himastatinicus ATCC 53653
95
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 27 - 2637 (3073)
[subject] 1786 - 4406 (10625)
(16 hsp)		 0.0 1970   49% FscC fscC Streptomyces sp. FR-008
96
 Q82QT5_STRAW
(Q82QT5)		 
[query] 6 - 2635 (3073)
[subject] 9 - 2658 (3564)
(4 hsp)		 0.0 1969   48% Modular polyketide synthase pteA2
SAV418
SAV_418		 Streptomyces avermitilis
97
 Q0R4M7_STRAT
(Q0R4M7)		 Jump to Chth_00270 
[query] 1 - 2629 (3073)
[subject] 12 - 2665 (3955)
(6 hsp)		 0.0 1966   46% ChlA2 Streptomyces antibioticus
98
 F4F7F4_VERMA
(F4F7F4)		 
[query] 29 - 2635 (3073)
[subject] 2540 - 4991 (5781)
(11 hsp)		 0.0 1963   49% Modular polyketide synthase VAB18032_16435 Verrucosispora maris (strain AB-18-032)
99
 C6WN16_ACTMD
(C6WN16)		 
[query] 23 - 2650 (3073)
[subject] 1110 - 3744 (4080)
(9 hsp)		 0.0 1962   49% Mycocerosate synthase., Erythronolide synthase Amir_4699 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) 2.3.1.111

2.3.1.94
100
 D7P611_CHOCO
(D7P611)		 
[query] 29 - 2629 (3073)
[subject] 2311 - 4966 (6255)
(12 hsp)		 0.0 1960   47% TugA tugA Chondromyces crocatus
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q8KUH4_ACTPA
(Q8KUH4)		 
[query] 1 - 3073 (3073)
[subject] 1 - 3073 (3073)
 0.0 5775   100%
Product
Polyketide synthase
Gene
asmB
Organism
Actinosynnema pretiosum subsp. auranticum
1uniprot[Pubmed] 12060743 [Medline] 22056096
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.(Proc. Natl. Acad. Sci. U.S.A.) [2002]
2
 C6W8L0_ACTMD
(C6W8L0)		 
[query] 564 - 3072 (3073)
[subject] 617 - 3147 (3148)
 0.0 4180   94%
Product
Acyl transferase
Gene
Amir_3198
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
4
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 1 - 2629 (3073)
[subject] 1 - 2666 (5588)
(7 hsp)		 0.0 2133   49%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
6
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 2 - 2629 (3073)
[subject] 5 - 2521 (3377)
(4 hsp)		 0.0 2129   50%
Product
Polyketide synthase type I
Gene
becF
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
7
 Q30CR9_STRAU
(Q30CR9)		 Jump to Alip_00160 
[query] 2 - 2629 (3073)
[subject] 3 - 2632 (3277)
(5 hsp)		 0.0 2126   49%
Product
LipPks4
Gene
lipPks4
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
9
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 8 - 2629 (3073)
[subject] 21 - 2519 (3373)
(5 hsp)		 0.0 2125   50%
Product
Polyketide synthase type I
Gene
mlaF
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
10
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 29 - 2629 (3073)
[subject] 3599 - 6201 (7110)
(11 hsp)		 0.0 2124   51%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
11
 Q82QT4_STRAW
(Q82QT4)		 
[query] 23 - 2629 (3073)
[subject] 4280 - 6826 (7746)
(16 hsp)		 0.0 2124   50%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
12
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 29 - 2629 (3073)
[subject] 1776 - 4406 (5321)
(6 hsp)		 0.0 2120   50%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
13
 Q0R4M8_STRAT
(Q0R4M8)		 Jump to Chth_00260 
[query] 3 - 2629 (3073)
[subject] 1055 - 3765 (4699)
(8 hsp)		 0.0 2119   50%
Product
ChlA1
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
16
 Q52V49_9ACTO
(Q52V49)		 
[query] 7 - 2629 (3073)
[subject] 9 - 2672 (3872)
(5 hsp)		 0.0 2102   49%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
17
 Q0S8W4_RHOSR
(Q0S8W4)		 
[query] 1 - 2632 (3073)
[subject] 1 - 2631 (3527)
(5 hsp)		 0.0 2101   49%
Product
Type I polyketide synthase
Gene
RHA1_ro04231
Organism
Rhodococcus sp. (strain RHA1)
1uniprot[Pubmed] 17030794
The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006]
20
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 18 - 2630 (3073)
[subject] 552 - 3154 (10827)
(18 hsp)		 0.0 2096   50%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
21
 F1CT52_9ACTO
(F1CT52)		 
[query] 1 - 2629 (3073)
[subject] 1 - 2683 (3418)
(5 hsp)		 0.0 2092   47%
Product
GdmAII
Gene
gdmAII
Organism
Streptomyces autolyticus
1uniprot[Pubmed] 21544574
Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011]
22
 C9YYI2_STRSW
(C9YYI2)		 
[query] 29 - 2629 (3073)
[subject] 38 - 2682 (3919)
(5 hsp)		 0.0 2087   50%
Product
Putative type I polyketide synthase
Gene
SCAB_83911
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
23
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 29 - 2632 (3073)
[subject] 3768 - 6361 (7488)
(9 hsp)		 0.0 2086   51%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
24
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 29 - 2629 (3073)
[subject] 1786 - 4409 (5339)
(7 hsp)		 0.0 2085   49%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
25
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 1 - 2629 (3073)
[subject] 5 - 2669 (4928)
(9 hsp)		 0.0 2084   49%
Product
Polyketide synthase extender modules 5-7
Gene
spnD
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
27
 D8HZ82_AMYMU
(D8HZ82)		 
[query] 29 - 2629 (3073)
[subject] 632 - 3054 (4735)
(11 hsp)		 0.0 2082   51%
Product
Rifamycin polyketide synthase
Gene
rifA
AMED_0617
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
28
 O54666_AMYMD
(O54666)		 Jump to Rifam_00210 
[query] 29 - 2629 (3073)
[subject] 632 - 3054 (4735)
(11 hsp)		 0.0 2082   51%
Product
RifA
Rifamycin polyketide synthase, type 1
Gene
rifA
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
30
 Q1WEK9_9ACTO
(Q1WEK9)		 
[query] 29 - 2629 (3073)
[subject] 2523 - 5049 (5712)
(11 hsp)		 0.0 2079   51%
Product
Polyketide synthase
Gene
merA
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
32
 C3VLZ4_9ACTO
(C3VLZ4)		 
[query] 5 - 2637 (3073)
[subject] 6 - 2493 (3365)
(4 hsp)		 0.0 2075   50%
Product
Polyketide synthase type I
Gene
mlaD
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
34
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 29 - 2631 (3073)
[subject] 1578 - 4202 (6831)
(10 hsp)		 0.0 2071   49%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
35
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 29 - 2630 (3073)
[subject] 1723 - 4280 (5176)
(7 hsp)		 0.0 2071   50%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
38
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 4 - 2629 (3073)
[subject] 5 - 2573 (5060)
(8 hsp)		 0.0 2062   49%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
39
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 4 - 2629 (3073)
[subject] 5 - 2573 (5060)
(8 hsp)		 0.0 2061   49%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
41
 Q3S863_9ACTO
(Q3S863)		 Jump to Conca_00070 
[query] 16 - 2627 (3073)
[subject] 24 - 2671 (3982)
(6 hsp)		 0.0 2060   49%
Product
Modular polyketide synthase
Gene
 
Organism
Streptomyces neyagawaensis
1uniprot[Pubmed] 16207901
Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449.(Microbiology) [2005]
45
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 23 - 2631 (3073)
[subject] 1556 - 4170 (6797)
(11 hsp)		 0.0 2055   49%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
46
 A0FCL1_STRVO
(A0FCL1)		 Jump to Merid_00020 
[query] 29 - 2629 (3073)
[subject] 2531 - 5051 (5721)
(11 hsp)		 0.0 2050   52%
Product
MerA
Gene
merA
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
47
 F8QPG1_9ACTO
(F8QPG1)		 
[query] 1 - 2629 (3073)
[subject] 1 - 2681 (3621)
(5 hsp)		 0.0 2048   49%
Product
Polyketide synthase
Gene
natD
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
50
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 24 - 2636 (3073)
[subject] 1677 - 4189 (5099)
(6 hsp)		 0.0 2043   50%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
51
 C3VLW6_9ACTO
(C3VLW6)		 
[query] 5 - 2637 (3073)
[subject] 6 - 2499 (3372)
(4 hsp)		 0.0 2042   50%
Product
Polyketide synthase type I
Gene
becD
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
52
 D7BRD4_STRBB
(D7BRD4)		 
[query] 35 - 2634 (3073)
[subject] 4604 - 7224 (9950)
(17 hsp)		 0.0 2040   50%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
53
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 3 - 2747 (3073)
[subject] 5 - 2714 (3596)
(4 hsp)		 0.0 2037   48%
Product
Polyketide synthase
Gene
idmM
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
54
 Q0QMN7_9ACTO
(Q0QMN7)		 
[query] 28 - 2668 (3073)
[subject] 1063 - 3682 (4290)
(8 hsp)		 0.0 2032   51%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces sp. Eco86
1uniprot[Pubmed] 16724457
Isolation and identification of three new 5-alkenyl-3,3(2H)-furanones from two streptomyces species using a genomic screening approach.(J. Antibiot.) [2006]
55
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 29 - 2631 (3073)
[subject] 1762 - 4373 (10917)
(16 hsp)		 0.0 2028   48%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
56
 A4FH85_SACEN
(A4FH85)		 
[query] 29 - 2629 (3073)
[subject] 1018 - 3608 (4327)
(8 hsp)		 0.0 2024   50%
Product
Type I modular polyketide synthase
Gene
SACE_4141
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
57
 Q5VKQ3_SACER
(Q5VKQ3)		 
[query] 29 - 2629 (3073)
[subject] 1018 - 3608 (4327)
(8 hsp)		 0.0 2024   50%
Product
Type I PKS
Gene
pkeAI
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15925898
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004]
58
 Q9EX53_STRCO
(Q9EX53)		 
[query] 4 - 2629 (3073)
[subject] 8 - 2671 (3576)
(5 hsp)		 0.0 2020   46%
Product
Putative type I polyketide synthase
Gene
SCO6274
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
59
 F1DI33_9ACTO
(F1DI33)		 
[query] 4 - 2680 (3073)
[subject] 5 - 2686 (2801)
(4 hsp)		 0.0 2017   48%
Product
TrdAIII
Gene
 
Organism
Streptomyces sp. SCSIO1666
1uniprot[Pubmed] 21329667
Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.(Biochem. Biophys. Res. Commun.) [2011]
61
 Q76KZ3_STRHA
(Q76KZ3)		 Jump to Vicen_00070 
[query] 1 - 2629 (3073)
[subject] 1 - 2638 (3808)
(4 hsp)		 0.0 2013   49%
Product
Polyketide synthase modules 7-8
Gene
vinP4
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
62
 E0D206_9ACTO
(E0D206)		 Jump to FD891_00050 
[query] 1 - 2649 (3073)
[subject] 1 - 2657 (3799)
(4 hsp)		 0.0 2012   49%
Product
Polyketide synthase
Gene
gfsE
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
63
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 22 - 2636 (3073)
[subject] 1015 - 3644 (6241)
(11 hsp)		 0.0 2011   50%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
64
 D3Y1I5_9ACTO
(D3Y1I5)		 
[query] 4 - 2680 (3073)
[subject] 5 - 2686 (2801)
(4 hsp)		 0.0 2006   47%
Product
TamAIII
Gene
 
Organism
Streptomyces sp. 307-9
1uniprot[Pubmed] 20127927
Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.(Chembiochem) [2010]
66
 A1YAM7_AMYOR
(A1YAM7)		 
[query] 2 - 2629 (3073)
[subject] 10 - 2494 (5723)
(8 hsp)		 0.0 2006   49%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
67
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 2 - 2629 (3073)
[subject] 3 - 2650 (5066)
(5 hsp)		 0.0 2003   48%
Product
Putative polyketide synthase
Gene
rubB
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
69
 Q93HE5_STRAW
(Q93HE5)		 
[query] 25 - 2629 (3073)
[subject] 971 - 3658 (4498)
(7 hsp)		 0.0 2000   48%
Product
Modular polyketide synthase
Putative modular polyketide synthase
Gene
pks5
SAV2368
SAV_2368
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
73
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 21 - 2633 (3073)
[subject] 7308 - 9925 (10876)
(13 hsp)		 0.0 1993   50%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
74
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 27 - 2635 (3073)
[subject] 1024 - 3670 (6383)
(10 hsp)		 0.0 1992   45%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
75
 Q846X2_STRCM
(Q846X2)		 Jump to Monen_00190 
[query] 1 - 2636 (3073)
[subject] 1 - 2755 (4106)
(5 hsp)		 0.0 1991   47%
Product
Monensin polyketide synthase modules 7 and 8
Gene
monAV
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 12940979 [Medline] 22823264
Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003]
2uniprot
The gene cluster for monensin biosynthesis. [1999]
76
 C6W8V0_ACTMD
(C6W8V0)		 
[query] 1 - 2629 (3073)
[subject] 1 - 2617 (3408)
(4 hsp)		 0.0 1991   50%
Product
Acyl transferase
Gene
Amir_3293
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
77
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 1 - 2629 (3073)
[subject] 6 - 2586 (5400)
(6 hsp)		 0.0 1990   49%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
80
 F8QPF8_9ACTO
(F8QPF8)		 
[query] 19 - 2688 (3073)
[subject] 1053 - 3701 (5698)
(9 hsp)		 0.0 1988   49%
Product
Polyketide synthase
Gene
natA
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
81
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 2 - 2637 (3073)
[subject] 3 - 2784 (5532)
(7 hsp)		 0.0 1987   48%
Product
Type I polyketide synthase AVES 3
Gene
aveA3
SAV942
SAV_942
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
84
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 2 - 2633 (3073)
[subject] 3 - 2632 (11096)
(16 hsp)		 0.0 1979   48%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
85
 D8HZ86_AMYMU
(D8HZ86)		 
[query] 1 - 2629 (3073)
[subject] 1 - 2565 (3413)
(5 hsp)		 0.0 1979   49%
Product
Rifamycin polyketide synthase
Gene
rifE
AMED_0621
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
86
 O54593_AMYMD
(O54593)		 Jump to Rifam_00250 
[query] 1 - 2629 (3073)
[subject] 1 - 2565 (3413)
(5 hsp)		 0.0 1979   49%
Product
RifE
Rifamycin polyketide synthase, type 1
Gene
rifE
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
88
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 27 - 2634 (3073)
[subject] 4118 - 6689 (7620)
(12 hsp)		 0.0 1978   48%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
2uniprot[Pubmed] 20623733
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.(Angew. Chem. Int. Ed.) [2010]
[pubmed all]
90
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 1 - 2646 (3073)
[subject] 1 - 2626 (7102)
(11 hsp)		 0.0 1976   48%
Product
Polyketide synthase
Gene
merB
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
92
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 27 - 2634 (3073)
[subject] 4075 - 6645 (7576)
(12 hsp)		 0.0 1974   48%
Product
Type I modular polyketide synthase
Gene
ttnB
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
93
 Q2PC83_STRAH
(Q2PC83)		 Jump to Rubra_00070 
[query] 29 - 2629 (3073)
[subject] 1003 - 3587 (5349)
(10 hsp)		 0.0 1971   48%
Product
Putative polyketide synthase
Gene
rubA
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
95
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 27 - 2637 (3073)
[subject] 1786 - 4406 (10625)
(16 hsp)		 0.0 1970   49%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
96
 Q82QT5_STRAW
(Q82QT5)		 
[query] 6 - 2635 (3073)
[subject] 9 - 2658 (3564)
(4 hsp)		 0.0 1969   48%
Product
Modular polyketide synthase
Gene
pteA2
SAV418
SAV_418
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
97
 Q0R4M7_STRAT
(Q0R4M7)		 Jump to Chth_00270 
[query] 1 - 2629 (3073)
[subject] 12 - 2665 (3955)
(6 hsp)		 0.0 1966   46%
Product
ChlA2
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
98
 F4F7F4_VERMA
(F4F7F4)		 
[query] 29 - 2635 (3073)
[subject] 2540 - 4991 (5781)
(11 hsp)		 0.0 1963   49%
Product
Modular polyketide synthase
Gene
VAB18032_16435
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
99
 C6WN16_ACTMD
(C6WN16)		 
[query] 23 - 2650 (3073)
[subject] 1110 - 3744 (4080)
(9 hsp)		 0.0 1962   49%
Product
Mycocerosate synthase., Erythronolide synthase
Gene
Amir_4699
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
100
 D7P611_CHOCO
(D7P611)		 
[query] 29 - 2629 (3073)
[subject] 2311 - 4966 (6255)
(12 hsp)		 0.0 1960   47%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]