BLAST table : Mith_00170

DB	UniProtKB

	accession	Evalue	Score	Ident.	link	product	gene	organism	ec
1	Q194Q8_STRAA (Q194Q8)	1e-138	493	100%	UniProt GenBank	Ketoreductase	mtmTI	Streptomyces argillaceus
2	D7BZS0_STRBB (D7BZS0)	9e-71	271	64%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	SBI_06855	Streptomyces bingchenggensis (strain BCW-1)
3	Q70J96_STRGR (Q70J96)	2e-57	227	54%	UniProt GenBank	Ketoreductase	cmmTI	Streptomyces griseus subsp. griseus
4	Q3S8Q3_STRRM (Q3S8Q3)	1e-52	211	54%	UniProt GenBank	OxyM	oxyM	Streptomyces rimosus
5	E8W962_STRFA (E8W962)	5e-51	205	51%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	Sfla_5328	Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
6	C0JWC4_9ACTO (C0JWC4)	7e-44	181	45%	UniProt GenBank	PokT1	pokT1	Streptomyces diastatochromogenes
7	B2V750_SULSY (B2V750)	2e-43	179	42%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	SYO3AOP1_0187	Sulfurihydrogenibium sp. (strain YO3AOP1)
8	C4FJM7_9AQUI (C4FJM7)	3e-43	179	42%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	SULYE_0776	Sulfurihydrogenibium yellowstonense SS-5	1.1.1.100 niceE keggE
9	C1DXR7_SULAA (C1DXR7)	6e-43	178	41%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier protein reductase)	SULAZ_0183	Sulfurihydrogenibium azorense (strain Az-Fu1 / DSM 15241 / OCM 825)	1.1.1.100 niceE keggE
10	A8V058_9AQUI (A8V058)	9e-41	171	40%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	HG1285_05530	Hydrogenivirga sp. 128-5-R1-1
11	C0QR70_PERMH (C0QR70)	4e-40	169	38%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier protein reductase)	PERMA_1399	Persephonella marina (strain DSM 14350 / EX-H1)	1.1.1.100 niceE keggE
12	E4M729_9FIRM (E4M729)	2e-36	157	42%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	ThesuDRAFT_0166	Thermaerobacter subterraneus DSM 13965
13	D5WTM5_BACT2 (D5WTM5)	2e-36	157	40%	UniProt GenBank	Enoyl-[acyl-carrier-protein] reductase [NADH]	Btus_2604	Bacillus tusciae (strain DSM 2912 / NBRC 15312 / T2)	1.3.1.9 niceE keggE
14	E8N5P0_ANATU (E8N5P0)	1e-35	154	39%	UniProt GenBank	Putative oxidoreductase	ANT_17280	Anaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1)
15	D1CG27_THET1 (D1CG27)	7e-35	151	38%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	Tter_0966	Thermobaculum terrenum (strain ATCC BAA-798 / YNP1)
16	B3QVF0_CHLT3 (B3QVF0)	1e-34	150	37%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	Ctha_2098	Chloroherpeton thalassium (strain ATCC 35110 / GB-78)
17	F8I8U5_9FIRM (F8I8U5)	1e-34	150	38%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	fabL TPY_3240	Sulfobacillus acidophilus TPY
18	F7TUI3_9BACL (F7TUI3)	2e-34	150	38%	UniProt GenBank	Enoyl-[acyl-carrier-protein] reductase	fabL BRLA_c18170	Brevibacillus laterosporus LMG 15441	1.3.1.10 niceE keggE
19	E8RFG2_9DELT (E8RFG2)	3e-34	149	39%	UniProt GenBank	Enoyl-[acyl-carrier-protein] reductase [NADH]	Despr_0937	Desulfobulbus propionicus DSM 2032	1.3.1.9 niceE keggE
20	A6CLS0_9BACI (A6CLS0)	3e-34	149	37%	UniProt GenBank	Enoyl-(Acyl carrier protein) reductase	BSG1_05649	Bacillus sp. SG-1	1.3.1.10 niceE keggE
21	F8IIQ6_ALIAC (F8IIQ6)	5e-34	149	39%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	fabG TC41_2687	Alicyclobacillus acidocaldarius Bacillus acidocaldarius
22	C0Z652_BREBN (C0Z652)	7e-34	148	38%	UniProt GenBank	Enoyl-[acyl-carrier-protein] reductase [NADH]	fabL BBR47_10320	Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599)	1.3.1.9 niceE keggE
23	P95727_STRCU (P95727)	9e-34	148	40%	UniProt GenBank	1-cyclohexenylcarbonyl CoA reductase	chcA	Streptomyces collinus
24	Q6V1M4_9ACTO (Q6V1M4)	9e-34	148	40%	UniProt GenBank	ChcA	chcA	Streptomyces sp. HK803
25	D5SX05_PLAL2 (D5SX05)	3e-33	146	39%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	Plim_1674	Planctomyces limnophilus (strain ATCC 43296 / DSM 3776 / IFAM 1008 / 290)
26	E5WR47_9BACI (E5WR47)	4e-33	145	35%	UniProt GenBank	Enoyl-(Acyl carrier protein) reductase	HMPREF1013_04937	Bacillus sp. 2_A_57_CT2
27	Q5WIF4_BACSK (Q5WIF4)	7e-33	145	37%	UniProt GenBank	Enoyl-[acyl-carrier-protein] reductase [NADH]	fabL ABC1313	Bacillus clausii (strain KSM-K16)	1.3.1.9 niceE keggE
28	Q2B348_9BACI (Q2B348)	1e-32	144	37%	UniProt GenBank	Enoyl-(Acyl carrier protein) reductase	B14911_14420	Bacillus sp. NRRL B-14911	1.3.1.10 niceE keggE
29	B7DNL6_9BACL (B7DNL6)	1e-32	144	39%	UniProt GenBank	Enoyl-[acyl-carrier-protein] reductase [NADH]	AaLAA1DRAFT_0591	Alicyclobacillus acidocaldarius LAA1	1.3.1.9 niceE keggE
30	C8WSC0_ALIAD (C8WSC0)	2e-32	144	39%	UniProt GenBank	Enoyl-[acyl-carrier-protein] reductase [NADH]	Aaci_2398	Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / 104-1A) Bacillus acidocaldarius	1.3.1.9 niceE keggE
31	C8WSD4_ALIAD (C8WSD4)	2e-32	143	38%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	Aaci_2412	Alicyclobacillus acidocaldarius subsp. acidocaldarius (strain ATCC 27009 / DSM 446 / 104-1A) Bacillus acidocaldarius
32	A0LU59_ACIC1 (A0LU59)	3e-32	143	38%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	Acel_1197	Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
33	F8IIR9_ALIAC (F8IIR9)	3e-32	143	38%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	fabL TC41_2700	Alicyclobacillus acidocaldarius Bacillus acidocaldarius
34	D3FUQ6_BACPE (D3FUQ6)	4e-32	142	36%	UniProt GenBank	Enoyl-(Acyl carrier protein) reductase	BpOF4_10865	Bacillus pseudofirmus (strain OF4)	1.3.1.10 niceE keggE
35	C5D5T3_GEOSW (C5D5T3)	5e-32	142	36%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	GWCH70_0470	Geobacillus sp. (strain WCH70)
36	F3Z6E4_9ACTO (F3Z6E4)	5e-32	142	39%	UniProt GenBank	Putative short-chain dehydrogenase/reductase SDR	STTU_5672	Streptomyces sp. Tu6071
37	B5GGE2_9ACTO (B5GGE2)	6e-32	142	39%	UniProt GenBank	Short chain dehydrogenase/reductase family oxidoreductase	SSBG_03351	Streptomyces sp. SPB74
38	E6U207_BACCJ (E6U207)	6e-32	142	35%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	Bcell_0978	Bacillus cellulosilyticus (strain ATCC 21833 / DSM 2522 / FERM P-1141 / JCM 9156 / N-4)
39	D9UEB1_9ACTO (D9UEB1)	6e-32	142	39%	UniProt GenBank	Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase	SSLG_00923	Streptomyces sp. SPB78
40	D7P5V2_9ACTO (D7P5V2)	2e-31	140	39%	UniProt GenBank	AsuB3	asuB3	Streptomyces nodosus subsp. asukaensis
41	B7DNK4_9BACL (B7DNK4)	3e-31	139	38%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	AaLAA1DRAFT_0579	Alicyclobacillus acidocaldarius LAA1
42	E3IF26_GEOS0 (E3IF26)	7e-31	138	36%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	GY4MC1_3310	Geobacillus sp. (strain Y4.1MC1)
43	F8D197_BACTR (F8D197)	7e-31	138	36%	UniProt GenBank	3-oxoacyl-(Acyl-carrier-protein) reductase	Geoth_3364	Geobacillus thermoglucosidasius C56-YS93	1.1.1.100 niceE keggE
44	B4BRN1_9BACI (B4BRN1)	1e-30	137	37%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	G11MC16DRAFT_3070	Geobacillus sp. G11MC16
45	Q5L2T0_GEOKA (Q5L2T0)	2e-30	137	36%	UniProt GenBank	Glucose 1-dehydrogenase	GK0465	Geobacillus kaustophilus
46	D6B3X6_9ACTO (D6B3X6)	3e-30	136	40%	UniProt GenBank	Reductase	SSHG_00067	Streptomyces albus J1074
47	E8SU11_GEOS2 (E8SU11)	4e-30	136	36%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	GYMC52_0468	Geobacillus sp. (strain Y412MC52)
48	D7D386_GEOSC (D7D386)	4e-30	136	36%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	GC56T3_3006	Geobacillus sp. (strain C56-T3)
49	C9RWZ1_GEOSY (C9RWZ1)	4e-30	136	36%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	GYMC61_1347	Geobacillus sp. (strain Y412MC61)
50	A4IKJ8_GEOTN (A4IKJ8)	5e-30	135	37%	UniProt GenBank	Enoyl-acyl carrier protein reductase FabI	fabI GTNG_0470	Geobacillus thermodenitrificans (strain NG80-2)
51	B1IH53_CLOBK (B1IH53)	5e-30	135	35%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	fabG CLD_0886	Clostridium botulinum (strain Okra / Type B1)	1.1.1.100 niceE keggE
52	B1G597_9BURK (B1G597)	1e-29	134	37%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	BgramDRAFT_4587	Burkholderia graminis C4D1M
53	C6D8S2_PAESJ (C6D8S2)	1e-29	134	33%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	Pjdr2_4638	Paenibacillus sp. (strain JDR-2)
54	Q9KEB5_BACHD (Q9KEB5)	1e-29	134	36%	UniProt GenBank	Glucose 1-dehydrogenase	BH0938	Bacillus halodurans
55	B1KU70_CLOBM (B1KU70)	2e-29	134	35%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	fabG CLK_3073	Clostridium botulinum (strain Loch Maree / Type A3)	1.1.1.100 niceE keggE
56	D5DXS1_BACMQ (D5DXS1)	2e-29	133	34%	UniProt GenBank	Short chain dehydrogenase	BMQ_0404	Bacillus megaterium (strain ATCC 12872 / QMB1551)	1.1.1.1 niceE keggE
57	D5DA14_BACMD (D5DA14)	3e-29	132	34%	UniProt GenBank	Short chain dehydrogenase	BMD_0405	Bacillus megaterium (strain DSM 319)	1.1.1.1 niceE keggE
58	A5I7X4_CLOBH (A5I7X4)	3e-29	132	35%	UniProt GenBank	3-oxoacyl-[acyl-carrier protein] reductase	fabG CBO3600	Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)	1.1.1.100 niceE keggE
59	D8NGA6_RALSO (D8NGA6)	6e-29	132	39%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	fabG CMR15_mp10276	Ralstonia solanacearum Pseudomonas solanacearum	1.1.1.100 niceE keggE
60	A7G954_CLOBH (A7G954)	6e-29	132	35%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	fabG-2 CLC_3578	Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)	1.1.1.100 niceE keggE
61	A7FPP0_CLOB1 (A7FPP0)	6e-29	132	35%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	fabG-2 CLB_3680	Clostridium botulinum (strain ATCC 19397 / Type A)	1.1.1.100 niceE keggE
62	Q8XT12_RALSO (Q8XT12)	6e-29	132	39%	UniProt GenBank	Probable dehydrogenase oxidoreductase protein	RSp0305	Ralstonia solanacearum Pseudomonas solanacearum
63	Q6D7W6_ERWCT (Q6D7W6)	6e-29	132	36%	UniProt GenBank	Probable short chain dehydrogenase	ECA1209	Erwinia carotovora subsp. atroseptica Pectobacterium atrosepticum
64	B0LJ23_9ACTO (B0LJ23)	7e-29	132	39%	UniProt GenBank	Lct40	lct40	Streptomyces rishiriensis
65	D9S342_THEOJ (D9S342)	8e-29	131	35%	UniProt GenBank	3-oxoacyl-(Acyl-carrier-protein) reductase	Toce_1057	Thermosediminibacter oceani (strain ATCC BAA-1034 / DSM 16646 / JW/IW-1228P)	1.1.1.100 niceE keggE
66	F3M4A9_9BACL (F3M4A9)	8e-29	131	33%	UniProt GenBank	Oxidoreductase, short chain dehydrogenase/reductase family protein	HMPREF9412_0303	Paenibacillus sp. HGF5
67	A6P1I6_9FIRM (A6P1I6)	9e-29	131	37%	UniProt GenBank	Putative uncharacterized protein	BACCAP_04353	Pseudoflavonifractor capillosus ATCC 29799
68	A8FB79_BACP2 (A8FB79)	1e-28	131	32%	UniProt GenBank	Enoyl-[acyl-carrier-protein] reductase (NADH)	fabL BPUM_0812	Bacillus pumilus (strain SAFR-032)	1.3.1.9 niceE keggE
69	B4ANX5_BACPU (B4ANX5)	1e-28	131	32%	UniProt GenBank	Enoyl-[acyl-carrier-protein] reductase	BAT_3272	Bacillus pumilus ATCC 7061
70	Q65M93_BACLD (Q65M93)	1e-28	131	34%	UniProt GenBank	Enoyl-acyl carrier protein reductase FabL	fabL BL03039 BLi00887	Bacillus licheniformis (strain DSM 13 / ATCC 14580)
71	E5W5K3_9BACI (E5W5K3)	1e-28	131	34%	UniProt GenBank	Unidentfied dehydrogenase	HMPREF1012_02160	Bacillus sp. BT1B_CT2
72	B1BC91_CLOBO (B1BC91)	1e-28	131	32%	UniProt GenBank	3-oxoacyl-(Acyl-carrier-protein) reductase	fabG CBC_1053	Clostridium botulinum C str. Eklund	1.1.1.100 niceE keggE
73	C3KWF3_CLOB6 (C3KWF3)	1e-28	131	35%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	fabG CLJ_B3929	Clostridium botulinum (strain 657 / Type Ba4)	1.1.1.100 niceE keggE
74	B1QMI3_CLOBO (B1QMI3)	1e-28	131	35%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	fabG CBB_3948	Clostridium botulinum Bf	1.1.1.100 niceE keggE
75	C1FNK3_CLOBJ (C1FNK3)	1e-28	130	35%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	fabG CLM_4092	Clostridium botulinum (strain Kyoto / Type A2)	1.1.1.100 niceE keggE
76	B1QFE1_CLOBO (B1QFE1)	1e-28	130	35%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	fabG CBN_3680	Clostridium botulinum NCTC 2916	1.1.1.100 niceE keggE
77	D6UVF1_9BACT (D6UVF1)	2e-28	130	35%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	AciX8DRAFT_3231	Acidobacterium sp. MP5ACTX8
78	E1UPB6_BACAS (E1UPB6)	2e-28	130	34%	UniProt GenBank	Enoyl-acyl carrier protein reductase III	fabL BAMF_0873	Bacillus amyloliquefaciens (strain ATCC 23350 / DSM 7 / NBRC 15535 / NRRL B-14393)	1.3.1.9 niceE keggE
79	F4EMJ1_BACAM (F4EMJ1)	2e-28	130	34%	UniProt GenBank	Enoyl-acyl carrier protein reductase III	fabL LL3_00935	Bacillus amyloliquefaciens Bacillus velezensis
80	F4E3E1_BACAM (F4E3E1)	2e-28	130	34%	UniProt GenBank	Enoyl-(Acyl carrier protein) reductase	fabL BAMTA208_03980	Bacillus amyloliquefaciens TA208	1.3.1.10 niceE keggE
81	D3E9A9_GEOS4 (D3E9A9)	2e-28	130	34%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	GYMC10_0253	Geobacillus sp. (strain Y412MC10)
82	C6IVS0_9BACL (C6IVS0)	2e-28	130	36%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	POTG_00247	Paenibacillus sp. oral taxon 786 str. D14
83	C0CLY3_9FIRM (C0CLY3)	2e-28	130	33%	UniProt GenBank	Putative uncharacterized protein	RUMHYD_01858	Blautia hydrogenotrophica DSM 10507
84	D5VZ70_CLOB2 (D5VZ70)	2e-28	130	35%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	fabG CBF_3792	Clostridium botulinum (strain 230613 / Type F)	1.1.1.100 niceE keggE
85	A7GJJ5_CLOBL (A7GJJ5)	2e-28	130	35%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	fabG CLI_3825	Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)	1.1.1.100 niceE keggE
86	E8ZRB5_CLOB0 (E8ZRB5)	2e-28	130	35%	UniProt GenBank	3-oxoacyl-[acyl-carrier protein] reductase	H04402_03699	Clostridium botulinum (strain H04402 065 / Type A5)	1.1.1.100 niceE keggE
87	D7B6U2_NOCDD (D7B6U2)	3e-28	130	40%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	Ndas_0044	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
88	B9BGR1_9BURK (B9BGR1)	3e-28	130	38%	UniProt GenBank	Multi-domain beta keto-acyl synthase	BURMUCGD1_2018	Burkholderia multivorans CGD1
89	D8MZ54_RALSO (D8MZ54)	3e-28	129	38%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	fabG RPSI07_mp0286	Ralstonia solanacearum PSI07	1.1.1.100 niceE keggE
90	D4RY72_9FIRM (D4RY72)	3e-28	129	34%	UniProt GenBank	3-oxoacyl-(Acyl-carrier-protein) reductase	BUTYVIB_00777	Butyrivibrio crossotus DSM 2876
91	D7B2P2_NOCDD (D7B2P2)	3e-28	129	39%	UniProt GenBank	Short-chain dehydrogenase/reductase SDR	Ndas_1303	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
92	C4X212_KLEPN (C4X212)	4e-28	129	37%	UniProt GenBank	Oxidoreductase	KP1_5211	Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044
93	A7Z2N2_BACA2 (A7Z2N2)	4e-28	129	33%	UniProt GenBank	FabL	fabL RBAM_008740	Bacillus amyloliquefaciens (strain FZB42)	1.3.1.9 niceE keggE
94	A6TFC4_KLEP7 (A6TFC4)	4e-28	129	38%	UniProt GenBank	Oxidoreductase	KPN78578_38340 KPN_03871	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)
95	A9ACE6_BURM1 (A9ACE6)	4e-28	129	38%	UniProt GenBank	Beta-ketoacyl synthase Putative multi-domain beta keto-acyl synthase	BMULJ_01288 Bmul_1953	Burkholderia multivorans (strain ATCC 17616 / 249)
96	F3Q3N2_9ENTR (F3Q3N2)	4e-28	129	38%	UniProt GenBank	Oxidoreductase, short chain dehydrogenase/reductase family protein	HMPREF9538_01683	Klebsiella sp. MS 92-3
97	F4C9J7_SPHS2 (F4C9J7)	5e-28	129	34%	UniProt GenBank	3-oxoacyl-(Acyl-carrier-protein) reductase	Sph21_4360	Sphingobacterium sp. (strain 21)	1.1.1.100 niceE keggE
98	A9FJV5_SORC5 (A9FJV5)	5e-28	129	41%	UniProt GenBank	3-oxoacyl-[acyl-carrier-protein] reductase	fabG9 sce4886	Sorangium cellulosum (strain So ce56) Polyangium cellulosum (strain So ce56)	1.1.1.100 niceE keggE
99	B5XN38_KLEP3 (B5XN38)	6e-28	128	37%	UniProt GenBank	Oxidoreductase, short chain dehydrogenase/reductase family	KPK_0236	Klebsiella pneumoniae (strain 342)
100	D6GL86_9ENTR (D6GL86)	6e-28	128	37%	UniProt GenBank	Short-chain alcohol dehydrogenase/reductase family oxidoreductase	HMPREF0485_03680	Klebsiella sp. 1_1_55

accession

alignment

Evalue

Score

Ident.

link

information

pubmed

Q194Q8_STRAA
(Q194Q8)

1e-138

493

100%

Product: Ketoreductase
Gene: mtmTI
Organism: Streptomyces argillaceus

[pubmed all]
1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]

D7BZS0_STRBB
(D7BZS0)

9e-71

271

64%

Product: Short-chain dehydrogenase/reductase SDR
Gene: SBI_06855
Organism: Streptomyces bingchenggensis (strain BCW-1)

1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]

Q3S8Q3_STRRM
(Q3S8Q3)

1e-52

211

54%

Product: OxyM
Gene: oxyM
Organism: Streptomyces rimosus

1uniprot[Pubmed] 16597959
Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase.(Appl. Environ. Microbiol.) [2006]

C0JWC4_9ACTO
(C0JWC4)

7e-44

181

45%

Product: PokT1
Gene: pokT1
Organism: Streptomyces diastatochromogenes

1uniprot[Pubmed] 19266534
Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin.(Chembiochem) [2009]

B2V750_SULSY
(B2V750)

2e-43

179

42%

Product: Short-chain dehydrogenase/reductase SDR
Gene: SYO3AOP1_0187
Organism: Sulfurihydrogenibium sp. (strain YO3AOP1)

1uniprot[Pubmed] 19136599
Complete and draft genome sequences of six members of the Aquificales.(J. Bacteriol.) [2009]

C1DXR7_SULAA
(C1DXR7)

6e-43

178

41%

Product: 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier protein reductase)
Gene: SULAZ_0183
Organism: Sulfurihydrogenibium azorense (strain Az-Fu1 / DSM 15241 / OCM 825)

1uniprot[Pubmed] 19136599
Complete and draft genome sequences of six members of the Aquificales.(J. Bacteriol.) [2009]

C0QR70_PERMH
(C0QR70)

4e-40

169

38%

Product: 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier protein reductase)
Gene: PERMA_1399
Organism: Persephonella marina (strain DSM 14350 / EX-H1)

1uniprot[Pubmed] 19136599
Complete and draft genome sequences of six members of the Aquificales.(J. Bacteriol.) [2009]

D1CG27_THET1
(D1CG27)

7e-35

151

38%

Product: Short-chain dehydrogenase/reductase SDR
Gene: Tter_0966
Organism: Thermobaculum terrenum (strain ATCC BAA-798 / YNP1)

1uniprot
Complete genome sequence of Thermobaculum terrenum type strain (YNP1T).(Stand. Genomic Sci.) [2010]

E8RFG2_9DELT
(E8RFG2)

3e-34

149

39%

Product: Enoyl-[acyl-carrier-protein] reductase [NADH]
Gene: Despr_0937
Organism: Desulfobulbus propionicus DSM 2032

1uniprot[Pubmed] 21475592
Complete genome sequence of Desulfobulbus propionicus type strain (1pr3).(Stand. Genomic Sci.) [2011]

P95727_STRCU
(P95727)

9e-34

148

40%

Product: 1-cyclohexenylcarbonyl CoA reductase
Gene: chcA
Organism: Streptomyces collinus

[pubmed all]
1uniprot[Pubmed] 8955309 [Medline] 97113449 Cloning and characterization of the gene encoding 1-cyclohexenylcarbonyl coenzyme A reductase from Streptomyces collinus.(J. Bacteriol.) [1996]
2uniprot[Pubmed] 10973220 [Medline] 20429626 Identification of a cyclohexylcarbonyl CoA biosynthetic gene cluster and application in the production of doramectin.(Nat. Biotechnol.) [2000]

Q6V1M4_9ACTO
(Q6V1M4)

9e-34

148

40%

Product: ChcA
Gene: chcA
Organism: Streptomyces sp. HK803

1uniprot[Pubmed] 12819191 [Medline] 22841069
Enhancement and selective production of phoslactomycin B, a protein phosphatase IIa inhibitor, through identification and engineering of the corresponding biosynthetic gene cluster.(J. Biol. Chem.) [2003]

D5SX05_PLAL2
(D5SX05)

3e-33

146

39%

Product: Short-chain dehydrogenase/reductase SDR
Gene: Plim_1674
Organism: Planctomyces limnophilus (strain ATCC 43296 / DSM 3776 / IFAM 1008 / 290)

1uniprot
Complete genome sequence of Planctomyces limnophilus type strain (Mu 290T).(Stand. Genomic Sci.) [2010]

D7P5V2_9ACTO
(D7P5V2)

2e-31

140

39%

Product: AsuB3
Gene: asuB3
Organism: Streptomyces nodosus subsp. asukaensis

1uniprot[Pubmed] 20522559
Biochemical and genetic insights into asukamycin biosynthesis.(J. Biol. Chem.) [2010]

Q5L2T0_GEOKA
(Q5L2T0)

2e-30

137

36%

Product: Glucose 1-dehydrogenase
Gene: GK0465
Organism: Geobacillus kaustophilus

1uniprot[Pubmed] 15576355
Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus.(Nucleic Acids Res.) [2004]

A4IKJ8_GEOTN
(A4IKJ8)

5e-30

135

37%

Product: Enoyl-acyl carrier protein reductase FabI
Gene: fabI
GTNG_0470
Organism: Geobacillus thermodenitrificans (strain NG80-2)

1uniprot[Pubmed] 17372208
Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir.(Proc. Natl. Acad. Sci. U.S.A.) [2007]

B1IH53_CLOBK
(B1IH53)

5e-30

135

35%

Product: 3-oxoacyl-[acyl-carrier-protein] reductase
Gene: fabG
CLD_0886
Organism: Clostridium botulinum (strain Okra / Type B1)

1uniprot[Pubmed] 18060065
Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids.(PLoS ONE) [2007]

Q9KEB5_BACHD
(Q9KEB5)

1e-29

134

36%

Product: Glucose 1-dehydrogenase
Gene: BH0938
Organism: Bacillus halodurans

1uniprot[Pubmed] 11058132 [Medline] 20512582
Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans and genomic sequence comparison with Bacillus subtilis.(Nucleic Acids Res.) [2000]

B1KU70_CLOBM
(B1KU70)

2e-29

134

35%

Product: 3-oxoacyl-[acyl-carrier-protein] reductase
Gene: fabG
CLK_3073
Organism: Clostridium botulinum (strain Loch Maree / Type A3)

1uniprot[Pubmed] 18060065
Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids.(PLoS ONE) [2007]

A5I7X4_CLOBH
(A5I7X4)

3e-29

132

35%

Product: 3-oxoacyl-[acyl-carrier protein] reductase
Gene: fabG
CBO3600
Organism: Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)

1uniprot[Pubmed] 17519437
Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes.(Genome Res.) [2007]

D8NGA6_RALSO
(D8NGA6)

6e-29

132

39%

Product: 3-oxoacyl-[acyl-carrier-protein] reductase
Gene: fabG
CMR15_mp10276
Organism: Ralstonia solanacearum
Pseudomonas solanacearum

1uniprot
Genomes of three tomato pathogens within the Ralstonia solanacearum species complex reveal significant evolutionary divergence.(BMC Genomics) [2010]

A7G954_CLOBH
(A7G954)

6e-29

132

35%

Product: 3-oxoacyl-[acyl-carrier-protein] reductase
Gene: fabG-2
CLC_3578
Organism: Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)

1uniprot[Pubmed] 18060065
Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids.(PLoS ONE) [2007]

A7FPP0_CLOB1
(A7FPP0)

6e-29

132

35%

Product: 3-oxoacyl-[acyl-carrier-protein] reductase
Gene: fabG-2
CLB_3680
Organism: Clostridium botulinum (strain ATCC 19397 / Type A)

1uniprot[Pubmed] 18060065
Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4 and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within plasmids.(PLoS ONE) [2007]

Q8XT12_RALSO
(Q8XT12)

6e-29

132

39%

Product: Probable dehydrogenase oxidoreductase protein
Gene: RSp0305
Organism: Ralstonia solanacearum
Pseudomonas solanacearum

1uniprot[Pubmed] 11823852 [Medline] 21681879
Genome sequence of the plant pathogen Ralstonia solanacearum.(Nature) [2002]

Q6D7W6_ERWCT
(Q6D7W6)

6e-29

132

36%

Product: Probable short chain dehydrogenase
Gene: ECA1209
Organism: Erwinia carotovora subsp. atroseptica
Pectobacterium atrosepticum

1uniprot[Pubmed] 15263089
Genome sequence of the enterobacterial phytopathogen Erwinia carotovora subsp. atroseptica and characterization of virulence factors.(Proc. Natl. Acad. Sci. U.S.A.) [2004]

B0LJ23_9ACTO
(B0LJ23)

7e-29

132

39%

Product: Lct40
Gene: lct40
Organism: Streptomyces rishiriensis

1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]

D9S342_THEOJ
(D9S342)

8e-29

131

35%

Product: 3-oxoacyl-(Acyl-carrier-protein) reductase
Gene: Toce_1057
Organism: Thermosediminibacter oceani (strain ATCC BAA-1034 / DSM 16646 / JW/IW-1228P)

1uniprot
Complete genome sequence of Thermosediminibacter oceani type strain (JW/IW-1228PT).(Stand. Genomic Sci.) [2010]

A8FB79_BACP2
(A8FB79)

1e-28

131

32%

Product: Enoyl-[acyl-carrier-protein] reductase (NADH)
Gene: fabL
BPUM_0812
Organism: Bacillus pumilus (strain SAFR-032)

1uniprot[Pubmed] 17895969
Paradoxical DNA repair and peroxide resistance gene conservation in Bacillus pumilus SAFR-032.(PLoS ONE) [2007]

Q65M93_BACLD
(Q65M93)

1e-28

131

34%

Product: Enoyl-acyl carrier protein reductase
FabL
Gene: fabL
BL03039
BLi00887
Organism: Bacillus licheniformis (strain DSM 13 / ATCC 14580)

[pubmed all]
1uniprot[Pubmed] 15383718 The complete genome sequence of Bacillus licheniformis DSM13, an organism with great industrial potential.(J. Mol. Microbiol. Biotechnol.) [2004]
2uniprot[Pubmed] 15461803 Complete genome sequence of the industrial bacterium Bacillus licheniformis and comparisons with closely related Bacillus species.(Genome Biol.) [2004]

E1UPB6_BACAS
(E1UPB6)

2e-28

130

34%

Product: Enoyl-acyl carrier protein reductase III
Gene: fabL
BAMF_0873
Organism: Bacillus amyloliquefaciens (strain ATCC 23350 / DSM 7 / NBRC 15535 / NRRL B-14393)

1uniprot[Pubmed] 21262282
Genome sequence of B. amyloliquefaciens type strain DSM7(T) reveals differences to plant-associated B. amyloliquefaciens FZB42.(J. Biotechnol.) [2011]

F4EMJ1_BACAM
(F4EMJ1)

2e-28

130

34%

Product: Enoyl-acyl carrier protein reductase III
Gene: fabL
LL3_00935
Organism: Bacillus amyloliquefaciens
Bacillus velezensis

1uniprot[Pubmed] 21551302
Complete Genome Sequence of Bacillus amyloliquefaciens LL3, Which Exhibits Glutamic Acid-Independent Production of Poly-{gamma}-Glutamic Acid.(J. Bacteriol.) [2011]

F4E3E1_BACAM
(F4E3E1)

2e-28

130

34%

Product: Enoyl-(Acyl carrier protein) reductase
Gene: fabL
BAMTA208_03980
Organism: Bacillus amyloliquefaciens TA208

1uniprot[Pubmed] 21515778
Complete Genome Sequence of Bacillus amyloliquefaciens TA208, a Strain for Industrial Production of Guanosine and Ribavirin.(J. Bacteriol.) [2011]

E8ZRB5_CLOB0
(E8ZRB5)

2e-28

130

35%

Product: 3-oxoacyl-[acyl-carrier protein] reductase
Gene: H04402_03699
Organism: Clostridium botulinum (strain H04402 065 / Type A5)

1uniprot[Pubmed] 21378191
Complete genome sequence of proteolytic Clostridium botulinum type A5 (B3') strain H04402 065.(J. Bacteriol.) [2011]

D7B6U2_NOCDD
(D7B6U2)

3e-28

130

40%

Product: Short-chain dehydrogenase/reductase SDR
Gene: Ndas_0044
Organism: Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei

1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]

D8MZ54_RALSO
(D8MZ54)

3e-28

129

38%

Product: 3-oxoacyl-[acyl-carrier-protein] reductase
Gene: fabG
RPSI07_mp0286
Organism: Ralstonia solanacearum PSI07

1uniprot
Genomes of three tomato pathogens within the Ralstonia solanacearum species complex reveal significant evolutionary divergence.(BMC Genomics) [2010]

D7B2P2_NOCDD
(D7B2P2)

3e-28

129

39%

Product: Short-chain dehydrogenase/reductase SDR
Gene: Ndas_1303
Organism: Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei

1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]

C4X212_KLEPN
(C4X212)

4e-28

129

37%

Product: Oxidoreductase
Gene: KP1_5211
Organism: Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044

1uniprot[Pubmed] 19447910
Genome sequencing and comparative analysis of Klebsiella pneumoniae NTUH-K2044, a strain causing liver abscess and meningitis.(J. Bacteriol.) [2009]

A7Z2N2_BACA2
(A7Z2N2)

4e-28

129

33%

Product: FabL
Gene: fabL
RBAM_008740
Organism: Bacillus amyloliquefaciens (strain FZB42)

1uniprot[Pubmed] 17704766
Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42.(Nat. Biotechnol.) [2007]

A9FJV5_SORC5
(A9FJV5)

5e-28

129

41%

Product: 3-oxoacyl-[acyl-carrier-protein] reductase
Gene: fabG9
sce4886
Organism: Sorangium cellulosum (strain So ce56)
Polyangium cellulosum (strain So ce56)

1uniprot[Pubmed] 17965706
Complete genome sequence of the myxobacterium Sorangium cellulosum.(Nat. Biotechnol.) [2007]

B5XN38_KLEP3
(B5XN38)

6e-28

128

37%

Product: Oxidoreductase, short chain dehydrogenase/reductase family
Gene: KPK_0236
Organism: Klebsiella pneumoniae (strain 342)

1uniprot[Pubmed] 18654632
Complete genome sequence of the N2-fixing broad host range endophyte Klebsiella pneumoniae 342 and virulence predictions verified in mice.(PLoS Genet.) [2008]