Amph_00030
Amph_00040 : CDS information
Location
| Organism | Streptomyces nodosus |
|---|---|
| Strain | ATCC 14899 (=NBRC 12895) |
| Entry name | Amphotericin B |
| Contig | AF357202 |
| Start / Stop / Direction | 5,042 / 33,574 / + [in whole cluster] 5,042 / 33,574 / + [in contig] |
| Location | 5042..33574 [in whole cluster] 5042..33574 [in contig] |
| Type | CDS |
| Length | 28,533 bp (9,510 aa) |
Annotation
| Category | 1.1 PKS |
|---|---|
| Product | polyketide synthase |
| Product (GenBank) | AmphI |
| Gene | |
| Gene (GenBank) | amphI |
| EC number | |
| Keyword | |
| Note | |
| Note (GenBank) |
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| Reference |
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PKS/NRPS Module
| 9 |  | malonyl-CoA |
| 10 |  | malonyl-CoA |
| 11 | | methylmalonyl-CoA |
| 12 | | malonyl-CoA |
| 13 |  | malonyl-CoA |
| 14 | | malonyl-CoA |
Sequence
>polyketide synthase [AmphI] MDNEQKLRDYLKLATADLRRARRRVGELESASQEPIAIVGMTCRYPGGVSSPEDLWRMVE AGENGVTPFPTDRGWDLEALASSPTSRGGFLHDAPEFDADFFGISPREAVAMDPQQRVVL ESAWEAFERAGINPTSVKGSRTGVFIGAMAQDYRVGPADGAEGFQLTGNTGSVLSGRISY TFGTVGPAVTVDTACSSSLVAVHLATQALRAGECTLALAGGVTVMSGPGTFIEMGRQGGL SVDGRCRSFGDTADGTGWAEGVGILVLERLSDAIRNGREILAVVRGTAVNQDGASNGLTA PNGPSQQAVIEQALVNARLSAGDIDVVEAHGTGTTLGDPVEAQALLATYGQQRDEDKPLL LGSVKSNISHTQAAAGVAGVIKMVMAMRHGVLPRTLLADEPTRHVDWSQGAVRVLTENTE WPATGAPRRAAVSSFGISGTNAHTIVEQAPEPEPADPEDDAPSTPAAVTGVLPVLLSGRS PEVLRAQAAALLTTLGTGTPPAPADLAYSLATTRTAFEHRAVLLASDLPELTGRLTAIAE GTDPAVLADTVTGTARTETRLAVLFTGQGAQRLGAGRELAARFPVFAAALDAALDAFTPH LDVPLRKVLWGEDADRLDRTEYAQPALFAVEVALYRLLESFEVKPDHLAGHSVGEIAAAH VAGVFSLDDAATLVAARGRLMQALPEGGAMVAVQASEDEVAPLLAGHEDLVSLAAVNGPS AVVLSGDETTVTELAARLAADGRKTSRLRVSHAFHSPLMAPMLDEFRNVVEGLTLHSPLL PVVSDVTGEPATVAQLTSPDYWVDHVRQAVRFADGIDWLARHDVTAFLELGPDSVLSAMA QNCLDAAGSDALTVPALREGRPEDHTFTAALAALHTQGTALHWDACFTGTGARRTDLPTY TFQRRRYWPRAVQGGAADLRSVGLGAAHHPLLSAAVSLADSEGALLTGRISLLSHPWLAD HTVRGATLLPGTAFLELAVRAGDEVGCDRVDELTLAAPLVLPEQGGVQVQLWIGNPDASG RRSVTVYGRPDADEDAPWTSHATGVLSASRTTSDFDATVWPPADAETLPVDGLYERLAEG GFGYGPLFQGLRAAWRRGDEVFAEVVLPESGHTDAESFGLHPALLDSALHAASFVDLDER AAGGLPFSWEGVSLHASGATTLRVRLAPAAGDAVAIAVADDSGQLVLSADSLILRAVAAR EIDAAAALVRDALFRLDWVPVTAVAASGTAAALVGEDPFGLRALPQFGDLAVHPDLADLA AADGAVPDTVLLPLTGTGPDADPVTAAHRAATEALAAVRTWLEQDERFAASRLALVTRGA TTGHDPAAAAVWGLVRSAQSENPGRFLLVDLDADQDTPALPAAALTSEEPQLAVRGEELR AARLVRRPASTAEAVPAFGGEGAVLVTGGTGGLGAVLARHLVAEHGVRELVLVSRRGGAA AGAAELVAELAESGARATVVACDVTDRAAVAELVAAHPVSAVVHSAGVLDDGMVGTLTPE RLTTVLRPKVDAAWNLHEATRDLDLKAFVLFSSVAGVLGSPGQANYAAGNAFLDALAAHR RAAGLPGLSLAWGPWEQTGGMTGGISEDDLRRMARAGTPALTVEQGLALLDAALDGDDAA LAPVRLDLSVLRAQGEVPPLLRSLIRGRSRRAAVAGSATAGGLAQRLARLDAESRDELVL DLVRGQVALVLGHATGAEIDAGRAFRELGFDSLTAVELRNRLNTVTGLRLPATLVFDYPT VSHLASYVLDELLGTEVEAEVVQRGTAAVADDPIVIVGMACRYPGGVTSPEDLWRLVTEG TDAVSGFPVNRGWDVENLYHPDPDHPGTAYTRSGGFLHEAGEFDPGFFGMSPREALATDS QQRLLLEASWEAIERAGIDPVGLRGSATGVFAGVMYSDYSAMLGSPEFEGFQGSGSSPSL ASGRVSYTLGLEGPAVTVDTACSSSLVAMHWAMQALRSGEISLALAGGVTVMSTPAVFVD FARQRGLSPDGRCKAFSDSADGVGWSEGVGMLVLERQSDAIRNGHQILAVVRGSAVNQDG ASNGLTAPNGPSQQRVIRQALASGGLSAGDVDVVEAHGTGTTLGDPIEAQALLATYGRDR DPEQPLLLGSVKSNIGHTQAAAGVAGVIKMVMSMRHGVLPRTLHVDAPSSHVDWTEGAVE LLTEQTAWPETGRPRRAAVSSFGISGTNVHTVLEQAPGTTVPAPAAPERTAGAVPLLLSG RTRDALRAQAARLLTHLQNHPEPSLADLGHSLATTRSRFERRAAVIAQDREGLLASLGSL AAGRPDPAVVEGEAAGRARVAVMFSGQGSQRAAMGRELYETQPRFAAAFDEVCAALDPLL DRPLREVVFAAEGSEEAALLDRTGWTQPALFAVEVALYRLVESWGVRADFVTGHSIGEIA AAHIAGVFTLQDAARLVAARATLMEALPSGGAMVAVQATEEEVAPLLGEGLSVAAVNGPT SVVVSGDEDPAVELAAEFSGRGRRTKRLRVSHAFHSPHMDAMLDAFRTVAETLSYAAPRI PLVSDLTGRRADDAEVRTADYWVRHVREAVRFADCVRTLRDAGATLFLELGPDGLLTAMA EDTLGDERYDHNTALVPLLRADRPEESAAATAAARLQIHGVDLDWTAYLAGTGARRVDLP TYAFQHAHYWPQLPSAAPSPAGDPADQKLWAAVERGDAAELAAVLGLDEDSLTPLDSLLP ALSSWRRGNQEKALLDTLRYRVEWTRLSKPAAPVLDGTWLLVSSDATADDETELLDGLAE ALGAHGARVRRLVLDADCADRAVLGARLADTENADNTAQVLSVLPLDERPTDGPAGFTQG LALTIALVQALADTGAHGRLWTATRGAVSTGPADPVTHPAQATAWGMGRGVALEHPRLWG GLVDLPADFDRGAGQRLAEVLAVKDAPDGEDQVALRATGVHGRRLVRHIVDELPSADQFT ASGSVLITGGTGGLGAETARWLARSGAAHLVLTSRRGPDAPGAAELRAELEQSGASVSIV ACDVADRDALAAVLDGLSADQPLTGVVHTAGVGHYGPLDALTPAEFAGLTAAKLAGAAHL DNLLGDRELDFFILFGSIAGVWGSGDQSAYGAANAYLDALALARRARGLAATSIAWGPWG GTGMAADDAVSGTLRRQGLGLLDPAPALTEMRRAVVRQDVTVTVADVDWTRYAPLFTSAR PSALISDLPEVRALAAENTPADTGDASEIVQRVRSLSEPEQLRLLTDLVRTEAATVLGHS SAGAVPEDRAFREIGFDSLTAVELRKHLGAATGLSLPSTMVFDYPTPLELAQYLRAEMVG SVLEVAGPVATGGTDDEPIAIIGMSCRYPGGVSSPEQLWDLVLSGTDAITDFPVNRGWNT AGLYDPDPDHPGTTYSTQGGFLHEADEFDPMFFGISPREALVMDPQQRLLLETTWEAFER AGLTPDTLRGSLTGTFIGSSYQEYGMGAGDGAEGHLVTGTSPSVLSGRLAYVFGLEGPAV TVDTACSSSLVALHLACQALRNGESNLAVAGGATVMTTPNAFVAFSRQRALAQDGRCKAF SESADGMTLAEGVGIVLVERLSDARRNGHPVLAVIRGSAINQDGASNGLSAPNGPSQQRV IRQALANARVAPGEIDLLEAHGTGTPLGDPIEAQALFATYGRTRTPETALLLGSVKSNIG HSQSAAGVASIIKMVMALRHGVMPQTLHADEPSSHVDWSPGTVRLLGENTDWPQTGRPRR AAVSSFGISGTNAHVILEQETEAPAAEDEQLAPAPLPVAAGVVPWLLSARGAAALREQAD RLLTHLVTADPAARPIDIGLSLATSRALFEHRAVVVPPAGTDPLEALRAVAADGPSGVVA RGVADVAGRTVFVFPGQGSQWAGMGAQLLDESPVFAERIAECAAALAEFTDWNLIDVLRG AEGAPTLERVDVVQPASFAVMVSLAAVWRAQGVEPDAVVGHSQGEIAAAVVSGALSLRDG ARVVTLRAQAIGRSLAGRGGMMSVALPVAEVEARLEAFEGRVSVAAENGPRSSVVAGEPE ALDELHAQLTAEEIRARRVAVDYASHSPHVEDLHDEILELLAEVAPRTSEIPFFSTVTGD WLDTTVMDAGYWYRSLRGRVLFADAVRDLIAADHRAFIEVSSHPVLAMSVQDMIDDAGVA GVASGTLRRDNGGLDRFLLSAAEVFVRGVQVDWAAVFEGTGASRVDLPTYAFQHENLWAM AAAPEAVTAADPEDAAFWTAVEDGDVSALTAALGTDEDSVAAVLPALSSWRRARKERSTV DSWRYRPTWKPVTKLPQRTLDGTWLLVSADGVDDTDVAEALETGGAEVRRLVLDESCTDR AVLRERLTDADGLTGIVSVLAGAERTGAVPGTGLVLGVALTVALVQALGDAGIDTPLWAL TRGAVSTGRSDKVTAPVQAQVTGIGWTAALECPGRWGGVVDLPETLDARAGQRLAAVLAG ALGDDDQIALRSSGVFTRRIVRADAAPDGSARDWKPRGTTLVTGGSGTLAPHLARWLAEQ GAEHLVLVSRRGPEAPGAAELRAELAERGTETTLAACDITDRDAVAALLESLKAEGRTVR TVVHTAATIELHTLDATTLDDFDRVLAAKVTGAQILDELLDDEELDDFVLYSSTAGMWGS GAHAAYVAGNAYLAALAEHRRARGLTALSLSWGIWADDLQLGRVDPQMIRRSGLEFMDPQ LALSGLKRALDDDEQVIAVADVDWETYHPVYTSARPTPLFDEVPEVQRLTAAAEQSAGDP ARGEFAAALLALPAAEQHRKLLETVRTEAASVLGLSSAEDLTDQRAFRDVGFDSLTAVGL RNRLASVTGLTLPSTMVFDYPNPAALAGFLHSELADVHSAGAVAVTAGAPVDDDPIAIVG MSCRYPGGITSAEQLWRVSLEEVDAVSVFPADRGWDAEALYDPDPDASGRTYSVQGGFLR DVADFDPGFFGISPREALSMDPQQRLLLETAWEVFENAGLDPVAQRGSRTGTFIGASYQD YGAAVPGSEGSEGHMITGSLPSVLSGRVSYLFGLEGPAVTLDTACSSSLVAIHLACQSLR NGESTLALAGGASIMSTPMSFIGFSRQRALAEDGRCKAYAEGADGMTLAEGVGLILLERL SDARRNGHEVLAVIRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGVEANDIDVLEGH GTGTALGDPIEAQALFATYGKDRDPERPVLLGSVKSNIGHTQMASGVASIIKLVHALREG VAPKSLHIDQPSTHVDWSSGTIQLLTERTEWPETGRPRRAAVSSFGLSGTNVHTVLEQAP AADAPAAEDTPAPRDALVPVLVSGRGEAALRAQAGALLDLLAERPGIHPTDLAFSLATSR AALEHRAAVVADDHEALVRGLTALRDGLPGAGLVQGRTGRGRTAFLFTGQGSQRLGMGRE LYERHPVFADALDAVLARIDGTTERPLRDVLFAAEGSQDAALLHRTGYAQPALFALEVAL FRLLESWGVTPDYLAGHSVGEIAAAHVAGVLDLDDACTLVAARGRLMQALPEGGAMVALE AAEDEVLPHLEGLADQVSVAAVNGPRSVVVAGEEEPVLALAAHFAEQGRRTKRLRVSHAF HSPLMDPMLDDFAAVARALTYHAPSIPFVSNVTGTLAAPEQVCTADYWVSHVRSAVRFAD GIGWLSTQGGVQTFLELGPDGVLSGMARESLTDASRTALLPTLRGDRPEEQALVTAVAAA HAHGFDVDWTAWFQGSGARRVALPTYAFQRERYWPDTTAAGITAPAPGSALDAEFWAAVE HADVASLTASLGLDDATVTAMVPALTAWRQRRGEQSALDSWRYRVTWKPRGGAPGAAPTG RWLVLVPAEHRDEATAAWAADVEAALATATVRVEVTGTDRAALAARLTEAADGDTFQGVL SLLALAPGDAGHPGAPAALTLTATALQALGDARIDAPLWNITRGAVAVGRSEQVTAPEQA AVWGLFRAAALELPARVGGSVDLPEDLDTQAARRLRGILAAADGEDAVAVRASGVFLRRL AHSPAADTVGSAFDPAAGTVLITGGTGGIGGHLARRLARDGAAHLLLTSRRGPDAPGAGE LRAELEESGARVTIAACDAADRDALAALLATVPEDAPLTAVFHTAGVVDDHVVDELTPES FATVLHAKTVAARHLHDLTAGHDLAAFVLFSSTAGLIGAAGQGNYAAANSQLDALAEQRR AQGLPALSVAWGPWAGSGMVADAAEIAARVRRGGFEPLDPASGVAALLRAVDNGDTSVAV ADIDWERFLRAFASARPLPLVADLPETAGANAPAAAAGTGSGLREQLAGLPAEERHAHVL DLLRTQVAAVLGHSDARTVDDDLAFRDLGFDSLTVLELRNALNALTGLSLPASLVYDHPT PREMADFLLAELLGSLPESTRHAVATRAVDEDPIAVVGLACRFPGGVSTPEELWQLLAEG RDGITGFPDDRNWDIAALGAGASDTLHGGFLAQVADFDARFFGISPREALAMDPQQRLLL ETTWEALERAGIDPAALRGSTTGVFVGTNGQDYPNLLRRSTSDVSGYVATGNTASVMSGR LSYALGLEGPAVTIDTACSSSLVALHWAGHALSAGECDLVVAGGVSVMSTPDSFVEFSTQ GGLAPDGHCKPFSDDADGTAWSEGVGILVLERLSDAIRNGHEVRGIIRGTAVNQDGASNG LTAPNGPSQQRVIRQALADARLAPSEIDAVEAHGTGTTLGDPIEAQALLNTYGPGRDTDQ PLLLGTVKSNIGHTQAAAGVAGVIKMLLAMQHGTLPRTLHVTSPTSHVDWSSGAVSLLTE ERDWPETGRPRRAGVSAFGVSGTNAHVIVEQAPIDEPVVEPTEEPAPAAEVTTVPWIVSG RSREALQDQVDRLTAYAAARPELSPLDVGRSLATDRTLFPHRAVLLAGPDGVREAARSVA SRTRGRTAFLFSGQGAQRALMGRELYERYPAFADALDTVLAQFDTALDFSLREVLFAEPG TPEAERLNETGWTQPALFAVEVALHRLVESWGLTPDQVAGHSIGEIAAAHVAGVFSLEDA CALVAARASLMQELPRGGAMLAVRATEEEVAPHLTERVSVAAVNGPSAVVVAGDEAEVAA IAAHFEAQDRKTTRLRVSHAFHSPLMDPMLTAFARVAESLTYHEPVIPLVSTVTGVPAGA ELLTPGYWVRHVRETVRFADGVRALREDGVTTFVEIGPDGQLTAAAQQTLDASGDEAPAT VVALQRRDRSEETTLLEGLATLHTQGAGPDWTAWFAGTGGHRVELPTYAFQRERYWPEPA APGATGVQDPVDAAFWAAVEREDLESLTASLGLDGDTVTTMVPALSAWRRRTDARSTARD WRYHESWTALGTPAHSAGAGRVLALVPAEHAGTDWAETLVAALGADPLVVDGTSGSLARE LADLVPQQATFAPSRRPARTLAAPAESPSTSSTGTSGRHTESTHRTPLLDGQTSPAGTLD PAGWTVVVSLLAAGTGTLPAPDAAPAAVLEALEAAGVDAPLWCVTRGAVSVAGEAPAAVG QAALWGMGRVAALEHPERFGGLADLAPDADAATAALLAAHLAEPGGEDQIAVRATGLFGR RLVRTAVAPGDSGWRPHGTVLVVGGTRAMGARAARWLAREGAARLVLTTSPADSATDTEE LRAELGRLGAEVTVAPYDGGDRDAARALLDGLTGLTAVVYADDTPADGPAAALAPVDTLA EAATGRSLDAFVLFGSVAGVWGVRGHTDEAAEGAYVDALARALRAEGTPALAVSWNAWAE LTDPSTTRHLRMNGLPVMDADAALTALAGAVADGSAAVTVADVRWDTFAPAHHETRPTAL FDGLPEARTALAGAARDRAEGATASDGYGRWLLEQPAADRDDILLALVSEKAALVLGHAD TTLVEPDLPFRDLGFDSLTAVDLRNQLTAATGITLPATLVFDHPNPAALAAHLRTELLGG ATDTAAPVAAPAATGDDPIVIVGMACRFPGGVNSPEDLWQLVLDEVDAVGDFPADRGWDL DALAGDGPGRSATDQGGFLYDATDFDPGLFGVSPREAMVMDPQQRILLEASWEALERAGI DPGTLRGSGTTGVFVGGGSGDYRPPAEYGQWQTAQSASLLSGRLAYTFGIQGPTVSVDTA CSSSLVALHLAAQALRSGECSIALAGGVTVMATPVGFVEFSAQGALSPDGRCRAFSEDAN GTGWSEGVGMLVVERLSDARRNGHRVLAVLRGSAINQDGASNGLTAPSGPAQQRVIRQAL ANARLEAADVDAVEAHGTGTKLGDPIEAQALLATYGQDRERPVLVGSLKANIGHTQAASG VGGVIKMVLAMQHGLLPRSLYTENPSSHVDWTAGNARLLTELTPWPESERVRRAAVSSFG ASGTNAHLILEQPEPVRQPVEGARPAEDGSPVPVLLSGRSQNALRAQARKLLAHVAGHPE ETVTDLARTLATTRAVFEHRAAVTAADRDALIAGLTAVAEGTTAAHIVEHQVERTGKHAV LFSGQGSQQLGMGRDLYERFPAFAEAFDAVLARLDGHLGASLRDVVWHGDQETLNETGHT QPALFAFEVALYRLVESWGVTPDFVAGHSVGEIAAAHVAGVLSLDDACRLVAARARLMQD LPRGGAMVAVEATEQEVAAELTEAVSIAAVNGPTSVVLAGAEDAVLAVAAVLAERGRRTS RLKVSHAFHSVLMDPMLAEFRKVAESLRYEAPRIAVVSNVTGDVAGADELCDADYWVRHV RGTVRFADGVTALAGRGVRVLLELGPDAVLSALAEQSAPDTVSIPAQRRNRDEVETLVAA LGRLHVHAAGPRWDAFFDAAPGSWLDLPTYAFQRGRFWPDTLPTAPQGGATAGEADGTDS AFWDAVAQEDFGSLESVLDVEGDALSKVLPALLDWRRRTSEETQLDSWRHRIVWKRLTGA AMAHRKPLTGTWLAVVPEGLGEDPWVTTALDALGTRVVRAEVGADGREAMAATLREAAGE GTRFGGVVSLLALRETVHGDVPEGVALTGTLLQALGDAGIEAPLWCVTRSAVSANRSDRP RRPLQAAVWGLGRVAALEYPNRWGGLVDLPERADERAAAGLAAVLAGLDGEDQVAVRGSA VLARRLVPAPDRGQSGAWDPTGTVLITGGTGAIGAHVARRLAKDGVQHLVLLSRRGAEAP GATALRDELQTLGAGVTLAACDASDRGQLAAVLDAIPDDRPLTAVLHAAGVLDDGVIDRL TPERYQKVFRAKVTSALLLDELTRDLDLAAFVLFSSASSAVGNPGQANYAAANAVLDALA EARRVQNLPATSVSWGAWGGGGMADGHGADDAARRAGVAAMDPDLAVESLLRLVTGKEPT AVVAEVDLDRFASAFGGARPSALLREFPGYRETVAAAAPASPEGTLADRLAGMAPARRLD TVVDLVRTRAAQVLGYPDIDAVGAERSFRDLGVDSLGAVELRNQLGAETGLSLPATLVFD HPTPLALGEFVLARLAPEEAGPAVSDEETEIRAVLASVPLDRLREIGVLEPLLQLAGRGG GAGDDEDGESVDSMTVADLVRAALNGQSDL
>polyketide synthase [AmphI] ATGGACAACGAACAGAAGCTCCGGGATTACCTCAAGCTTGCGACGGCCGATCTGCGACGC GCCCGGCGGCGTGTGGGCGAGCTGGAGTCGGCGTCCCAGGAACCGATCGCCATCGTCGGT ATGACCTGCCGCTACCCAGGCGGCGTCAGCAGCCCCGAGGACCTGTGGCGGATGGTGGAG GCCGGCGAGAACGGCGTCACCCCGTTCCCCACCGACCGCGGCTGGGACCTGGAGGCGCTC GCCTCCTCGCCGACCTCCCGGGGCGGATTCCTCCATGACGCGCCCGAGTTCGACGCGGAC TTCTTCGGCATCTCGCCGCGCGAGGCGGTCGCCATGGACCCGCAGCAGCGGGTCGTCCTG GAGTCCGCCTGGGAGGCGTTCGAGCGCGCCGGCATCAACCCCACCTCCGTCAAGGGCAGC CGTACCGGCGTCTTCATCGGCGCCATGGCCCAGGACTACCGGGTCGGTCCCGCCGACGGC GCCGAGGGCTTCCAGCTCACCGGCAACACCGGCAGCGTGCTGTCCGGCCGTATCTCGTAC ACCTTCGGCACGGTCGGTCCCGCGGTCACCGTCGACACCGCCTGTTCCTCCTCCCTGGTC GCCGTCCACCTCGCCACCCAGGCGCTGCGCGCGGGTGAGTGCACCCTCGCCCTCGCGGGC GGCGTCACCGTCATGTCGGGCCCCGGCACCTTCATCGAGATGGGCCGCCAGGGCGGACTG TCCGTCGACGGCCGCTGCCGCTCCTTCGGCGACACCGCCGACGGCACCGGCTGGGCCGAG GGCGTCGGCATCCTCGTCCTGGAGCGGCTGTCCGACGCGATCCGCAACGGCCGCGAGATC CTCGCCGTGGTCCGCGGCACCGCCGTCAACCAGGACGGCGCCTCCAACGGGCTCACCGCC CCCAACGGCCCGTCGCAGCAGGCCGTCATCGAGCAGGCCCTCGTCAACGCCCGGCTCTCC GCGGGCGATATCGACGTCGTCGAGGCGCACGGCACCGGCACCACCCTCGGCGACCCCGTC GAGGCGCAGGCGCTGCTCGCCACCTACGGTCAGCAGCGCGACGAGGACAAGCCGCTGCTG CTCGGCTCGGTGAAGTCCAACATCAGCCACACCCAGGCCGCCGCCGGTGTCGCCGGTGTC ATCAAGATGGTCATGGCGATGCGGCATGGGGTGCTGCCCCGCACCCTCCTCGCCGACGAG CCCACCCGCCACGTCGACTGGTCCCAGGGCGCCGTCCGCGTCCTCACCGAGAACACCGAA TGGCCCGCCACCGGCGCCCCCCGCCGCGCGGCCGTCTCCTCCTTCGGCATCAGCGGCACC AACGCCCACACCATCGTCGAGCAGGCCCCCGAGCCGGAGCCCGCCGACCCCGAGGACGAC GCCCCGAGCACCCCGGCCGCCGTCACCGGCGTGCTGCCCGTGCTGCTCTCCGGCCGGAGC CCCGAGGTGCTGCGCGCCCAGGCCGCCGCCCTGCTCACCACCCTCGGCACCGGCACCCCG CCCGCGCCGGCGGACCTCGCCTACTCGCTCGCCACCACCCGCACCGCTTTCGAGCACCGG GCCGTGCTGCTCGCCTCGGACCTGCCCGAGCTGACCGGGCGGCTCACCGCGATCGCCGAG GGCACCGATCCGGCCGTCCTGGCCGACACCGTCACCGGCACCGCGAGAACCGAGACCCGC CTCGCCGTCCTGTTCACCGGGCAGGGCGCCCAGCGTCTCGGCGCCGGCCGTGAACTGGCC GCCCGCTTCCCGGTGTTCGCCGCCGCCCTGGACGCCGCCCTCGACGCCTTCACCCCCCAC CTGGACGTGCCGCTGCGCAAGGTGCTGTGGGGCGAGGACGCCGACCGCCTGGACCGCACC GAGTACGCACAGCCCGCGCTGTTCGCCGTCGAGGTCGCCCTCTACCGTCTGCTGGAGTCC TTCGAGGTCAAGCCGGACCACCTGGCCGGCCACTCGGTGGGCGAGATCGCCGCCGCGCAT GTCGCCGGAGTGTTCTCCCTCGACGACGCGGCCACCCTGGTCGCCGCCCGCGGCCGTCTC ATGCAGGCGCTGCCCGAGGGCGGCGCCATGGTCGCCGTGCAGGCGAGCGAGGACGAGGTC GCCCCGCTGCTCGCCGGCCACGAGGACCTGGTGTCCCTCGCCGCCGTCAACGGCCCCTCC GCCGTCGTCCTCTCCGGGGACGAGACCACCGTCACCGAGCTGGCGGCCCGCCTGGCCGCC GACGGACGCAAGACGAGCAGGCTGCGTGTCTCGCACGCCTTCCACTCGCCGCTGATGGCC CCGATGCTCGACGAGTTCCGGAACGTCGTCGAGGGCCTCACCCTGCACAGCCCGCTGCTG CCCGTCGTCTCCGACGTCACCGGAGAGCCGGCCACCGTCGCCCAGCTCACCTCCCCCGAC TACTGGGTCGACCATGTCCGTCAGGCCGTCCGCTTCGCCGACGGCATCGACTGGCTCGCC CGGCACGATGTCACCGCCTTCCTCGAACTCGGCCCCGACAGCGTGCTGTCCGCCATGGCG CAGAACTGCCTGGACGCCGCAGGATCCGACGCCCTCACCGTGCCCGCACTGCGCGAGGGC CGCCCCGAGGACCACACCTTCACCGCCGCGCTCGCCGCGCTGCACACCCAGGGCACCGCG CTGCACTGGGACGCCTGCTTCACCGGCACCGGAGCCCGCCGCACCGACCTGCCGACGTAC ACCTTCCAGCGCCGCCGCTACTGGCCGCGCGCCGTCCAGGGCGGCGCCGCCGACCTGCGC TCCGTCGGACTCGGCGCCGCCCACCACCCGCTGCTGTCCGCCGCGGTCTCCCTCGCCGAC TCCGAGGGCGCCCTGCTGACCGGCCGGATCTCCCTGCTCAGCCACCCGTGGCTCGCCGAC CACACCGTCCGCGGCGCCACCCTGCTGCCCGGCACCGCCTTCCTGGAGCTGGCCGTCCGC GCCGGCGACGAGGTCGGCTGCGACCGCGTCGACGAACTGACCCTGGCCGCACCGCTCGTC CTGCCCGAGCAGGGCGGCGTCCAGGTGCAGCTGTGGATCGGCAACCCGGACGCGTCCGGC CGCCGCAGCGTCACCGTCTACGGCCGGCCCGACGCCGACGAGGACGCCCCCTGGACGTCC CACGCCACCGGTGTGCTCTCCGCCTCCCGCACCACCAGCGACTTCGACGCCACCGTCTGG CCCCCGGCCGACGCCGAGACCCTCCCCGTGGACGGCCTCTACGAGCGGCTCGCCGAGGGC GGCTTCGGCTACGGCCCGCTCTTCCAGGGCCTGCGGGCCGCCTGGCGCCGCGGCGACGAG GTGTTCGCCGAGGTCGTGCTGCCCGAGTCCGGCCACACCGACGCCGAGTCCTTCGGACTG CACCCCGCGCTCCTCGACTCCGCCCTGCACGCGGCGTCGTTCGTCGACCTCGACGAGCGC GCCGCCGGCGGACTGCCCTTCTCCTGGGAGGGCGTCAGCCTGCACGCGAGCGGTGCCACC ACCCTGCGGGTGCGGCTGGCCCCGGCCGCCGGTGACGCCGTCGCGATCGCCGTCGCCGAC GACTCCGGACAGCTCGTCCTGTCCGCCGACTCGCTGATCCTGCGCGCCGTCGCGGCCCGC GAGATCGACGCCGCCGCCGCGCTGGTCCGCGACGCGCTGTTCCGCCTCGACTGGGTGCCC GTCACGGCCGTCGCCGCCTCCGGCACCGCCGCGGCACTGGTCGGCGAGGACCCCTTCGGC CTGCGCGCCCTGCCCCAGTTCGGCGACCTCGCCGTCCACCCGGATCTCGCGGATCTGGCC GCCGCCGACGGCGCTGTCCCGGACACCGTGCTGCTGCCGCTCACCGGCACCGGACCCGAC GCCGACCCGGTCACCGCCGCACACCGGGCCGCCACCGAGGCCCTCGCCGCCGTCCGGACC TGGCTCGAGCAGGACGAGCGGTTCGCCGCCTCCCGGCTCGCCCTGGTCACCCGGGGCGCG ACCACCGGCCACGACCCGGCCGCCGCCGCGGTCTGGGGCCTGGTGCGCTCCGCCCAGTCC GAGAACCCCGGCCGCTTCCTCCTCGTCGACCTCGACGCCGACCAGGACACCCCCGCGCTC CCGGCCGCCGCGCTCACCTCCGAGGAGCCGCAGCTCGCCGTGCGCGGCGAGGAGCTCCGC GCCGCCCGTCTGGTCCGCCGTCCCGCTTCCACCGCCGAGGCCGTTCCCGCCTTCGGTGGG GAGGGTGCGGTGTTGGTGACGGGTGGTACCGGTGGTCTGGGTGCGGTGCTGGCGCGTCAT CTGGTGGCCGAGCACGGTGTGCGTGAGCTGGTTCTGGTCAGTCGTCGTGGTGGTGCGGCG GCGGGTGCGGCCGAGCTGGTCGCGGAGCTGGCGGAGTCGGGTGCGCGGGCGACGGTGGTG GCCTGTGATGTGACGGACCGTGCGGCGGTGGCCGAGCTGGTGGCCGCGCATCCGGTGTCG GCGGTGGTGCACTCCGCCGGTGTCCTGGACGACGGCATGGTCGGCACGCTGACCCCCGAA CGCCTCACCACCGTGCTCCGTCCCAAGGTGGACGCGGCCTGGAACCTCCATGAGGCCACC CGCGACCTGGACCTGAAGGCCTTTGTGCTGTTCTCGTCGGTCGCCGGCGTCCTGGGCAGC CCCGGTCAGGCCAACTACGCCGCAGGCAACGCCTTCCTGGACGCCCTCGCGGCCCACCGC CGGGCCGCGGGCCTGCCGGGTCTGTCGCTGGCCTGGGGCCCCTGGGAGCAGACCGGCGGC ATGACCGGCGGCATCTCCGAGGACGACCTGCGCCGCATGGCCCGCGCCGGAACTCCGGCC CTCACCGTCGAGCAGGGCCTCGCCCTCCTCGACGCCGCCCTCGACGGCGACGACGCCGCG CTCGCCCCCGTCCGCCTGGACCTCTCCGTCCTGCGGGCCCAGGGCGAAGTGCCGCCGCTG CTGCGCTCCCTGATCCGCGGCCGCTCCCGCCGTGCCGCCGTCGCCGGGTCCGCCACCGCC GGCGGGCTCGCCCAGCGTCTGGCCCGCCTGGACGCCGAGAGCCGCGACGAACTGGTCCTG GACCTCGTCCGCGGCCAGGTCGCCCTCGTCCTCGGTCACGCCACCGGCGCCGAGATCGAC GCCGGCCGCGCCTTCCGTGAGCTGGGCTTCGACTCCCTCACCGCCGTCGAGCTGCGCAAC CGCCTGAACACGGTCACCGGACTGCGCCTGCCCGCCACCCTGGTCTTCGACTACCCGACG GTCAGCCACCTCGCCTCCTATGTCCTGGACGAGCTTCTCGGCACCGAGGTCGAGGCGGAG GTCGTGCAGCGCGGCACGGCGGCCGTGGCGGACGATCCGATCGTGATCGTGGGCATGGCC TGCCGCTATCCGGGCGGGGTCACCTCGCCGGAGGACCTGTGGCGCCTGGTCACCGAGGGC ACGGACGCCGTCTCCGGCTTCCCCGTCAACCGTGGCTGGGACGTGGAGAACCTCTACCAC CCGGACCCCGACCACCCCGGCACCGCCTACACGCGTTCCGGTGGTTTCCTGCACGAGGCG GGGGAGTTCGACCCCGGCTTCTTCGGTATGAGCCCCCGTGAGGCGCTGGCGACGGACTCG CAGCAGCGTCTGCTCCTCGAGGCGTCCTGGGAGGCGATCGAGCGGGCCGGGATCGATCCG GTCGGTCTGCGGGGCAGTGCGACCGGTGTGTTCGCCGGTGTGATGTACAGCGACTACAGC GCGATGCTGGGAAGCCCCGAGTTCGAGGGCTTCCAGGGCAGCGGCAGCTCTCCGAGTCTC GCCTCGGGCCGCGTCTCCTACACGCTGGGCCTGGAGGGTCCGGCGGTCACGGTGGACACC GCGTGCTCCTCGTCGCTGGTGGCGATGCACTGGGCGATGCAGGCCCTGCGCTCGGGTGAG ATCTCGCTCGCCCTGGCCGGCGGTGTGACCGTGATGTCCACGCCCGCCGTGTTCGTGGAC TTCGCGCGGCAGCGGGGTCTGTCGCCCGACGGCCGCTGCAAGGCGTTCTCGGACTCGGCC GATGGTGTGGGCTGGTCCGAGGGTGTCGGCATGCTGGTGCTGGAGCGGCAGTCCGACGCG ATCCGCAACGGCCACCAGATCCTCGCGGTCGTCCGCGGTTCGGCCGTCAACCAGGACGGC GCCTCCAACGGCCTCACCGCCCCCAACGGCCCGTCCCAGCAGCGCGTCATCCGCCAGGCC CTCGCCAGTGGTGGGCTCTCGGCGGGCGACGTGGATGTCGTCGAGGCGCACGGTACGGGT ACCACCCTGGGTGACCCGATCGAGGCGCAGGCGCTCCTGGCGACCTACGGCCGGGACCGT GACCCGGAGCAGCCGCTGCTGCTGGGTTCGGTGAAGTCCAACATCGGTCACACGCAGGCC GCGGCCGGTGTCGCGGGTGTGATCAAGATGGTCATGTCGATGCGCCACGGTGTACTGCCC CGCACCCTGCACGTGGACGCCCCGTCCTCGCACGTCGACTGGACCGAAGGCGCGGTCGAG CTGCTCACCGAGCAGACCGCCTGGCCCGAGACCGGCCGTCCGCGTCGCGCCGCCGTGTCC TCCTTCGGCATCAGCGGCACCAATGTCCACACCGTCCTGGAGCAGGCGCCGGGCACCACC GTGCCCGCCCCGGCCGCCCCCGAGCGCACCGCCGGCGCCGTCCCGCTGCTGCTGTCCGGC CGCACCCGCGACGCCCTGCGCGCCCAGGCCGCCCGCCTGCTCACCCACCTCCAGAACCAC CCCGAGCCGTCCCTCGCCGACCTCGGCCACTCCCTGGCCACCACCCGCTCCCGCTTCGAG CGCCGCGCCGCGGTGATCGCGCAGGACCGCGAAGGACTGCTCGCCTCCCTCGGCTCCCTC GCCGCCGGCCGCCCCGACCCGGCCGTCGTCGAGGGTGAGGCCGCCGGGCGTGCCCGGGTC GCCGTGATGTTCTCCGGCCAGGGCAGCCAGCGCGCCGCCATGGGCCGCGAACTGTACGAG ACCCAGCCCCGGTTCGCCGCCGCGTTCGACGAGGTGTGCGCCGCCCTCGACCCGCTGCTC GACCGGCCGCTGCGCGAGGTCGTGTTCGCCGCCGAGGGCAGCGAAGAGGCCGCGCTGCTC GACCGCACCGGCTGGACCCAGCCCGCGCTGTTCGCCGTCGAGGTCGCCCTCTACCGACTT GTCGAGAGCTGGGGCGTCCGCGCCGACTTCGTCACCGGTCACTCCATCGGTGAGATCGCC GCCGCGCACATCGCCGGGGTGTTCACCCTCCAGGACGCCGCCCGACTGGTCGCCGCCCGC GCCACCCTCATGGAGGCGCTGCCGTCCGGCGGCGCCATGGTCGCCGTGCAGGCCACCGAG GAAGAGGTCGCCCCGCTGCTCGGCGAGGGCCTGTCCGTCGCCGCCGTCAACGGCCCCACC TCCGTGGTCGTCTCCGGCGACGAGGACCCCGCCGTGGAGCTCGCCGCCGAGTTCTCCGGC CGAGGGCGCCGCACCAAGCGTCTACGGGTGAGCCATGCCTTCCACTCGCCGCACATGGAC GCCATGCTCGACGCGTTCCGCACGGTCGCCGAGACGCTGTCCTACGCCGCCCCCCGCATC CCGCTGGTCTCCGACCTGACGGGCCGCAGGGCCGACGACGCCGAGGTGCGCACCGCCGAC TACTGGGTGCGCCACGTCCGTGAGGCCGTACGGTTCGCCGACTGCGTCCGCACCCTGCGC GACGCCGGCGCCACCCTCTTCCTCGAACTCGGCCCCGACGGACTGCTGACCGCCATGGCC GAGGACACCCTCGGCGACGAGCGTTACGACCACAACACGGCACTCGTCCCGCTGCTGCGC GCCGACCGCCCCGAGGAGAGCGCCGCCGCCACCGCCGCGGCCCGCCTCCAGATCCACGGC GTCGACCTCGACTGGACCGCGTACCTGGCCGGCACCGGCGCCCGCCGCGTCGACCTGCCG ACCTACGCCTTCCAGCACGCCCACTACTGGCCGCAGCTGCCCTCCGCCGCGCCCTCCCCG GCCGGCGACCCGGCCGACCAGAAGCTGTGGGCCGCCGTCGAGCGCGGCGACGCCGCCGAA CTCGCCGCCGTCCTCGGCCTCGACGAGGACAGCCTCACCCCGCTGGACTCCCTGCTGCCC GCGCTGAGCTCCTGGCGCCGCGGCAACCAGGAGAAGGCGCTCCTCGACACGCTGCGCTAC CGCGTCGAGTGGACCCGGCTGAGCAAGCCCGCCGCCCCCGTCCTCGACGGCACCTGGCTG CTGGTCTCCTCCGACGCCACCGCCGACGACGAGACCGAGCTGCTCGACGGCCTGGCCGAG GCGCTCGGCGCGCACGGCGCCCGGGTCCGCCGCCTCGTCCTGGACGCCGACTGCGCCGAC CGGGCCGTGCTCGGCGCCCGCCTCGCCGACACCGAGAACGCCGACAACACCGCCCAGGTG CTGTCCGTGCTGCCGCTCGACGAGCGCCCCACCGACGGCCCCGCCGGCTTCACCCAGGGC CTCGCCCTGACCATCGCCCTCGTCCAGGCCCTCGCCGACACCGGCGCCCACGGCCGGCTG TGGACCGCCACCCGCGGCGCCGTCTCCACCGGACCCGCCGACCCGGTCACCCACCCCGCC CAGGCCACCGCCTGGGGCATGGGCCGCGGTGTCGCCCTGGAGCACCCCCGCCTGTGGGGC GGCCTCGTCGACCTCCCGGCCGACTTCGACCGCGGCGCCGGACAGCGCCTCGCCGAGGTC CTCGCGGTCAAGGACGCCCCCGACGGCGAGGACCAGGTCGCCCTGCGCGCCACCGGTGTG CACGGCCGCCGCCTGGTCCGCCACATCGTCGACGAGCTGCCCTCCGCCGACCAGTTCACC GCCTCCGGAAGCGTCCTGATCACCGGCGGCACCGGCGGCCTCGGCGCCGAGACCGCCCGC TGGCTGGCCCGCTCCGGCGCCGCCCACCTCGTCCTCACCAGCCGCCGCGGCCCCGACGCC CCCGGCGCCGCCGAACTCCGCGCCGAACTGGAGCAGTCGGGCGCAAGCGTCTCGATCGTG GCCTGCGACGTCGCCGACCGTGACGCCCTCGCCGCCGTCCTCGACGGACTGTCCGCCGAC CAGCCCCTCACCGGTGTGGTGCACACCGCGGGCGTCGGCCACTACGGCCCGCTGGACGCG CTGACGCCCGCCGAGTTCGCCGGCCTCACCGCCGCCAAGCTGGCCGGCGCCGCCCACCTC GACAACCTCCTCGGCGACCGCGAACTGGACTTCTTCATCCTGTTCGGCTCCATCGCCGGC GTCTGGGGCAGCGGCGACCAGAGCGCCTACGGCGCTGCCAACGCCTACCTCGACGCCCTC GCCCTGGCCCGCCGCGCCCGCGGCCTCGCCGCGACCTCCATCGCCTGGGGTCCCTGGGGC GGCACCGGCATGGCCGCCGACGACGCCGTCTCCGGCACCCTGCGACGCCAGGGCCTCGGC CTGCTCGACCCCGCGCCCGCCCTCACCGAGATGCGCCGCGCCGTGGTCCGCCAGGACGTC ACCGTCACCGTCGCGGACGTCGACTGGACCCGCTACGCCCCGCTGTTCACCTCCGCCCGG CCCAGCGCCCTCATCAGCGACCTGCCCGAGGTCCGTGCCCTGGCCGCCGAGAACACCCCC GCCGACACCGGCGACGCCTCCGAGATCGTCCAGCGGGTCCGCTCGCTGTCGGAGCCGGAG CAACTGCGCCTGCTCACCGACCTGGTGCGCACCGAGGCCGCGACCGTGCTCGGTCACTCC TCCGCCGGCGCCGTACCGGAGGACCGTGCCTTCCGCGAGATCGGCTTCGACTCGCTGACC GCCGTCGAACTGCGCAAGCACCTCGGCGCCGCCACCGGCCTCTCGCTGCCGAGCACCATG GTGTTCGACTACCCGACCCCGCTGGAGCTGGCCCAGTATCTGCGGGCCGAGATGGTCGGC TCCGTCCTGGAGGTCGCGGGCCCCGTCGCCACCGGCGGTACCGACGACGAACCCATCGCC ATCATCGGCATGAGCTGCCGCTACCCCGGCGGAGTCAGCTCCCCGGAGCAGCTGTGGGAC CTGGTGCTCTCCGGCACCGACGCGATCACCGACTTCCCGGTCAACCGCGGCTGGAACACC GCCGGGCTCTACGACCCCGACCCCGACCACCCTGGCACCACCTACTCCACGCAGGGCGGC TTCCTGCACGAGGCCGACGAGTTCGACCCCATGTTCTTCGGCATCTCGCCCCGCGAGGCG CTGGTCATGGACCCGCAGCAGCGGCTCCTCCTGGAGACCACCTGGGAGGCCTTCGAACGC GCCGGACTCACCCCCGACACCCTCCGCGGCAGCCTGACCGGCACCTTCATCGGCTCCAGC TACCAGGAGTACGGGATGGGCGCCGGCGACGGCGCCGAGGGCCACCTGGTCACCGGCACC AGCCCCAGCGTGCTCTCCGGCCGCCTCGCCTATGTCTTCGGCCTGGAGGGCCCGGCGGTC ACCGTCGACACCGCCTGCTCGTCCTCGCTGGTCGCCCTGCACCTGGCCTGCCAGGCGCTG CGCAACGGCGAGAGCAACCTCGCGGTCGCGGGCGGCGCCACCGTCATGACCACCCCCAAC GCGTTCGTGGCGTTCAGCCGGCAGCGCGCCCTCGCGCAGGACGGCCGGTGCAAGGCGTTC TCCGAGAGCGCCGACGGCATGACCCTCGCCGAAGGTGTCGGCATCGTCCTCGTCGAGCGG CTGTCCGACGCCCGCCGCAACGGCCACCCGGTGCTCGCCGTGATCCGCGGCTCCGCCATC AACCAGGACGGCGCCTCCAACGGCCTCAGCGCCCCCAACGGCCCCTCCCAGCAGCGCGTC ATCCGCCAGGCCCTGGCCAACGCCCGGGTCGCCCCCGGCGAGATCGACCTCCTGGAGGCC CACGGCACCGGCACCCCGCTCGGCGACCCCATCGAGGCGCAGGCCCTGTTCGCCACCTAC GGCCGCACCCGTACCCCCGAGACCGCGCTGCTGCTCGGCTCGGTGAAGTCGAACATCGGG CACTCCCAGTCCGCCGCCGGTGTCGCGAGCATCATCAAGATGGTCATGGCGCTGCGCCAC GGTGTGATGCCCCAGACCCTGCACGCCGACGAGCCCTCCAGCCACGTCGACTGGAGCCCG GGCACCGTACGGCTGCTCGGCGAGAACACCGACTGGCCGCAGACGGGCCGTCCGCGCCGG GCCGCGGTGTCCTCCTTCGGCATCAGCGGTACCAACGCCCACGTCATCCTGGAGCAGGAG ACCGAGGCGCCCGCCGCCGAGGACGAGCAGCTCGCCCCGGCGCCCCTGCCGGTCGCCGCC GGTGTGGTGCCGTGGCTGCTGTCCGCCCGTGGCGCCGCCGCGCTGCGCGAGCAGGCCGAC CGCCTCCTCACCCATCTCGTGACCGCCGACCCGGCGGCCCGCCCGATCGACATCGGTCTG TCCCTGGCCACCTCCCGCGCGCTCTTCGAGCACCGCGCCGTGGTCGTGCCGCCCGCCGGC ACCGACCCGCTGGAGGCGCTGCGCGCCGTCGCCGCAGACGGGCCCTCGGGCGTCGTCGCC CGCGGTGTCGCGGACGTCGCGGGCCGCACCGTCTTCGTCTTCCCCGGCCAGGGCTCCCAG TGGGCGGGCATGGGCGCCCAGCTCCTGGACGAGTCCCCGGTGTTCGCCGAGCGGATCGCC GAATGCGCCGCCGCCCTCGCCGAGTTCACCGACTGGAACCTCATCGACGTCCTGCGGGGC GCCGAGGGCGCCCCGACGCTGGAGCGCGTCGACGTCGTCCAGCCCGCCTCGTTCGCCGTG ATGGTCTCCCTGGCCGCCGTGTGGCGGGCCCAGGGTGTCGAACCCGACGCGGTGGTCGGC CACTCGCAGGGCGAGATCGCCGCCGCGGTGGTCTCCGGCGCCCTGTCGCTGCGCGACGGC GCCCGGGTCGTGACGCTCCGCGCCCAGGCCATCGGCCGCAGCCTCGCCGGGCGCGGCGGC ATGATGTCGGTGGCGCTGCCCGTCGCCGAGGTGGAGGCCCGTCTGGAGGCGTTCGAGGGA CGGGTGTCCGTCGCCGCCGAGAACGGCCCCCGCTCCTCCGTCGTCGCGGGCGAGCCCGAG GCCCTGGACGAACTGCACGCACAGCTCACCGCCGAGGAGATCCGGGCCCGCCGGGTCGCC GTGGACTACGCCTCGCACTCCCCCCATGTCGAGGACCTGCACGACGAGATCCTCGAACTG CTGGCCGAGGTCGCGCCGCGGACGTCCGAGATCCCGTTCTTCTCGACCGTCACCGGCGAC TGGCTCGACACCACCGTCATGGACGCCGGCTACTGGTACCGCAGCCTGCGCGGCCGGGTG CTGTTCGCGGACGCAGTCCGTGACCTGATCGCCGCCGACCACCGTGCCTTCATCGAGGTC AGCTCCCACCCCGTGCTCGCCATGTCCGTCCAGGACATGATCGACGACGCCGGAGTGGCG GGTGTCGCCTCCGGCACCCTGCGCCGCGACAACGGCGGTCTCGACCGCTTCCTGCTGTCC GCCGCCGAGGTGTTCGTCCGCGGTGTCCAGGTCGACTGGGCCGCCGTGTTCGAGGGGACC GGTGCGTCCCGGGTCGACCTGCCCACCTATGCCTTCCAGCACGAGAACCTGTGGGCCATG GCCGCCGCCCCGGAGGCCGTCACCGCGGCCGACCCCGAGGACGCCGCGTTCTGGACCGCC GTCGAGGACGGGGACGTCTCCGCCCTGACCGCGGCCCTCGGCACCGACGAGGACTCCGTC GCCGCCGTGCTGCCCGCGCTGTCCTCCTGGCGCCGGGCCCGCAAGGAGCGCTCCACCGTC GACTCCTGGCGCTACCGCCCGACCTGGAAGCCCGTCACCAAGCTCCCGCAGCGCACCCTG GACGGCACCTGGCTGCTGGTGTCCGCCGACGGCGTCGACGACACCGACGTCGCCGAGGCG CTGGAGACGGGCGGCGCCGAGGTGCGCCGGCTCGTCCTGGACGAGAGCTGCACCGACCGC GCCGTGCTGCGCGAGCGCCTCACCGACGCCGACGGCCTGACCGGCATCGTCTCCGTCCTC GCGGGCGCCGAGCGGACCGGTGCCGTCCCCGGCACCGGGCTCGTCCTCGGGGTCGCCCTC ACCGTCGCCCTCGTCCAGGCGCTCGGCGACGCCGGTATCGACACCCCGCTGTGGGCCCTG ACCCGCGGCGCCGTCTCCACCGGCCGCTCCGACAAGGTCACCGCGCCCGTCCAGGCCCAG GTCACCGGCATCGGCTGGACCGCCGCGCTGGAGTGCCCGGGACGCTGGGGCGGTGTCGTC GACCTGCCCGAGACACTGGACGCCCGCGCGGGCCAGCGGCTCGCGGCCGTCCTCGCCGGC GCGCTCGGCGACGACGACCAGATCGCCCTGCGCTCCTCCGGCGTCTTCACCCGCCGTATC GTCCGCGCCGACGCCGCCCCCGACGGCTCCGCCCGCGACTGGAAGCCGCGCGGCACCACC CTGGTCACCGGCGGCTCCGGCACCCTCGCCCCGCACCTGGCGCGCTGGCTCGCCGAGCAG GGCGCCGAACACCTGGTCCTGGTCAGCCGGCGCGGCCCCGAGGCGCCCGGCGCCGCCGAA CTCCGCGCCGAGCTGGCGGAACGCGGCACCGAGACGACCCTCGCCGCCTGCGACATCACC GACCGTGACGCCGTCGCCGCCCTCCTCGAAAGCCTGAAGGCCGAGGGCCGCACCGTCCGC ACGGTGGTGCACACCGCGGCCACCATCGAACTGCACACCCTCGACGCCACCACCCTCGAC GACTTCGACCGCGTCCTCGCCGCCAAGGTCACCGGCGCGCAGATCCTCGACGAACTCCTC GACGACGAGGAGCTGGACGACTTCGTCCTGTACTCCTCCACCGCCGGCATGTGGGGCAGC GGCGCGCACGCCGCGTATGTCGCGGGCAACGCCTATCTGGCGGCCCTCGCCGAGCACCGG CGCGCCCGCGGCCTGACCGCCCTGTCGCTGTCCTGGGGCATCTGGGCCGACGACCTCCAG CTCGGCCGAGTCGACCCGCAGATGATCCGCCGCAGCGGCCTGGAGTTCATGGACCCGCAG CTCGCGCTGAGCGGCCTCAAGCGGGCCCTCGACGACGACGAGCAGGTCATCGCGGTCGCC GACGTCGACTGGGAGACGTACCACCCCGTCTACACCTCGGCCCGGCCCACCCCGCTGTTC GACGAGGTCCCCGAGGTGCAGCGGCTCACCGCCGCTGCCGAGCAGAGCGCCGGGGACCCC GCCCGGGGCGAGTTCGCCGCCGCGCTGCTGGCCCTGCCCGCCGCCGAACAGCACCGCAAG CTGCTGGAGACCGTCCGCACCGAGGCCGCCTCCGTGCTCGGCCTGTCCTCCGCGGAGGAC CTCACCGACCAGCGCGCCTTCCGCGACGTCGGCTTCGACTCGCTGACCGCCGTCGGGCTG CGCAACCGGCTCGCGTCCGTCACCGGGCTGACGCTGCCGTCCACGATGGTCTTCGACTAC CCGAACCCGGCCGCCCTGGCCGGCTTCCTCCACTCCGAACTGGCCGACGTCCACTCCGCG GGCGCCGTCGCCGTCACCGCCGGCGCGCCCGTCGACGACGACCCGATCGCCATCGTCGGC ATGAGCTGCCGCTACCCCGGCGGCATCACCTCCGCCGAGCAGCTGTGGCGGGTCTCGCTG GAGGAGGTCGACGCGGTCTCCGTCTTCCCGGCCGACCGCGGCTGGGACGCCGAGGCCCTC TACGACCCCGACCCGGACGCCTCCGGCCGCACCTACTCGGTCCAGGGCGGCTTCCTGCGC GACGTCGCCGACTTCGACCCCGGCTTCTTCGGCATCTCGCCCCGCGAGGCCCTGTCGATG GACCCGCAGCAGCGCCTGCTCCTCGAGACGGCCTGGGAGGTCTTCGAGAACGCCGGCCTC GACCCGGTCGCCCAGCGCGGCAGCCGCACCGGCACCTTCATCGGCGCCAGCTACCAGGAC TACGGCGCCGCCGTGCCCGGCAGCGAGGGCTCCGAGGGCCATATGATCACCGGCTCGCTG CCCAGCGTGCTGTCCGGCCGAGTCTCCTACCTCTTCGGCCTCGAGGGCCCGGCCGTCACC CTCGACACCGCCTGCTCGTCCTCGCTGGTCGCGATCCACCTGGCCTGCCAGTCGCTGCGC AACGGCGAGAGCACCCTCGCCCTCGCCGGCGGTGCCAGCATCATGTCCACCCCCATGTCG TTCATCGGCTTCAGCCGGCAGCGGGCCCTCGCCGAGGACGGCCGCTGCAAGGCGTACGCC GAGGGCGCCGACGGCATGACCCTCGCCGAGGGCGTCGGCCTGATCCTGCTGGAGCGGCTC TCCGACGCCCGCCGCAACGGCCACGAGGTCCTCGCCGTCATCCGCGGCTCCGCCGTCAAC CAGGACGGCGCCTCCAACGGACTGACCGCCCCCAACGGCCCCTCCCAGCAGCGCGTCATC CGCCAGGCCCTCGCCAACGCGGGCGTCGAGGCGAACGACATCGACGTCCTGGAGGGCCAC GGCACCGGCACCGCCCTCGGCGACCCGATCGAGGCGCAGGCCCTGTTCGCCACCTACGGC AAGGACCGCGACCCCGAGCGGCCCGTGCTGCTCGGCTCGGTGAAGTCCAACATCGGCCAC ACTCAGATGGCCTCCGGCGTCGCCAGCATCATCAAGCTGGTCCACGCCCTGCGGGAGGGC GTCGCCCCCAAGTCGCTCCACATCGACCAGCCGTCCACCCATGTCGACTGGTCCTCCGGC ACCATCCAGCTGCTCACCGAGCGCACCGAGTGGCCCGAGACCGGCCGTCCGCGCCGCGCC GCCGTGTCGTCCTTCGGACTCAGCGGCACCAATGTCCACACCGTCCTGGAGCAGGCCCCC GCCGCCGACGCCCCGGCCGCCGAGGACACCCCCGCACCGCGGGACGCCTTGGTGCCCGTC CTCGTCTCCGGACGCGGCGAGGCGGCCCTGCGCGCCCAGGCCGGAGCCCTGCTCGACCTG CTGGCCGAGCGCCCCGGCATCCACCCCACCGATCTGGCGTTCTCCCTCGCCACCTCGCGC GCCGCCCTCGAGCACCGTGCCGCGGTCGTCGCCGACGACCACGAGGCACTGGTGCGCGGT CTGACCGCACTGCGCGACGGACTGCCCGGCGCCGGACTCGTCCAGGGCCGCACCGGCCGC GGACGCACCGCCTTCCTGTTCACCGGACAGGGCAGCCAGCGCCTTGGCATGGGCCGCGAA CTCTACGAACGCCACCCGGTGTTCGCCGACGCCCTGGACGCGGTGCTCGCCCGGATCGAC GGCACCACCGAACGCCCCCTGCGCGACGTGCTGTTCGCCGCCGAGGGCTCCCAGGACGCC GCCCTGCTCCACCGCACCGGCTACGCACAGCCCGCGCTGTTCGCCCTCGAAGTGGCGCTG TTCCGGCTGCTGGAGTCGTGGGGCGTGACCCCCGACTACCTGGCCGGGCACTCCGTCGGC GAGATCGCCGCCGCGCATGTCGCCGGCGTCCTCGACCTCGACGACGCGTGCACCCTGGTG GCCGCCCGCGGCCGGCTGATGCAGGCACTGCCCGAGGGCGGCGCGATGGTCGCCCTGGAG GCCGCCGAGGACGAGGTGCTGCCGCACCTGGAGGGCCTCGCCGACCAGGTCTCCGTGGCC GCCGTCAACGGGCCCCGGTCCGTCGTCGTCGCCGGCGAGGAGGAGCCCGTGCTCGCCCTC GCCGCGCACTTCGCCGAACAGGGGCGCCGCACCAAGCGTCTGCGGGTGAGCCATGCCTTC CACTCGCCGCTCATGGACCCGATGCTGGACGACTTCGCCGCCGTGGCCCGTGCTCTCACG TACCACGCGCCGTCGATCCCGTTCGTCTCCAATGTGACCGGCACCCTCGCCGCCCCCGAG CAGGTGTGCACCGCCGACTACTGGGTCTCCCACGTCCGCTCCGCCGTGCGCTTCGCCGAC GGCATCGGCTGGCTGTCCACCCAGGGCGGCGTCCAGACCTTCCTGGAGCTCGGCCCCGAC GGTGTGCTCAGCGGCATGGCCCGCGAGAGCCTCACCGACGCCTCCCGCACGGCGCTGCTG CCCACCCTGCGCGGCGACCGCCCGGAGGAGCAGGCCCTGGTCACCGCCGTCGCCGCGGCC CACGCCCATGGCTTCGACGTCGACTGGACCGCCTGGTTCCAGGGCAGCGGCGCCCGCCGG GTGGCCCTGCCCACCTACGCCTTCCAGCGCGAGCGGTACTGGCCCGACACCACCGCGGCC GGCATCACCGCCCCCGCCCCCGGCTCCGCACTGGACGCCGAGTTCTGGGCCGCGGTGGAA CACGCCGACGTCGCCTCGCTCACCGCCTCCCTCGGCCTGGACGACGCGACCGTCACCGCG ATGGTCCCGGCGCTCACCGCCTGGCGGCAGCGCCGCGGCGAACAGTCCGCGCTCGACTCC TGGCGCTACCGCGTCACCTGGAAGCCGCGCGGCGGCGCCCCCGGCGCCGCACCCACCGGA CGCTGGCTCGTCCTGGTCCCGGCCGAGCACCGCGACGAGGCCACCGCCGCCTGGGCCGCC GATGTCGAGGCCGCCCTCGCCACCGCCACCGTCCGCGTGGAGGTCACCGGCACCGACCGC GCCGCCCTCGCCGCCCGGCTCACCGAGGCCGCCGACGGCGACACCTTCCAGGGTGTGCTG TCGCTGCTGGCGCTGGCGCCCGGTGACGCCGGACACCCCGGCGCCCCGGCCGCGCTCACC CTCACCGCCACCGCCCTCCAGGCGCTCGGCGACGCCCGTATCGACGCCCCGCTGTGGAAC ATCACCCGCGGAGCCGTCGCCGTCGGCCGCTCCGAGCAGGTCACGGCACCCGAACAGGCC GCCGTATGGGGCCTGTTCCGCGCCGCCGCCCTCGAACTGCCCGCCCGCGTCGGCGGCAGC GTCGACCTCCCGGAGGACCTCGACACCCAGGCCGCCCGACGGCTGCGCGGGATCCTGGCC GCCGCCGACGGCGAGGACGCCGTCGCCGTCCGCGCCAGCGGCGTCTTCCTGCGCCGGCTC GCCCACAGCCCCGCCGCCGACACCGTCGGCTCCGCCTTCGACCCGGCGGCCGGCACCGTC CTGATCACCGGCGGCACCGGCGGCATCGGCGGACACCTCGCCCGCCGCCTCGCCCGCGAC GGCGCCGCCCATCTGCTGCTCACCAGCCGCCGCGGCCCCGACGCCCCCGGCGCCGGCGAA CTCCGCGCCGAACTGGAGGAGTCGGGCGCCCGTGTCACGATCGCCGCCTGCGACGCCGCC GACCGCGACGCGCTCGCCGCACTCCTCGCCACGGTGCCCGAGGACGCGCCCCTCACCGCC GTCTTCCACACCGCGGGCGTCGTCGACGACCATGTGGTGGACGAGCTGACCCCGGAGAGC TTCGCCACCGTCCTGCATGCCAAGACGGTCGCCGCCCGCCATCTGCACGACCTCACCGCC GGCCACGACCTCGCCGCGTTCGTCCTGTTCTCCTCGACCGCCGGCCTGATCGGCGCCGCC GGACAGGGCAACTACGCCGCCGCCAACTCCCAGCTCGACGCCCTCGCCGAGCAGCGCCGC GCCCAGGGCCTGCCCGCCCTGTCCGTGGCCTGGGGACCCTGGGCCGGCTCCGGCATGGTC GCCGACGCCGCCGAGATCGCCGCCCGGGTGCGCCGCGGCGGATTCGAACCGCTCGACCCC GCCTCCGGTGTCGCCGCGCTGCTGCGCGCCGTCGACAACGGCGACACCTCCGTCGCCGTC GCCGACATCGACTGGGAACGCTTCCTGCGCGCCTTCGCGTCGGCCCGCCCGCTGCCGCTC GTCGCCGACCTCCCGGAGACGGCGGGCGCCAACGCCCCGGCGGCGGCCGCCGGCACCGGC TCAGGCCTGCGCGAGCAGCTCGCCGGCCTGCCCGCCGAGGAGCGCCACGCACATGTCCTC GATCTGCTGCGTACCCAGGTGGCGGCCGTCCTCGGCCACTCCGACGCCCGCACCGTCGAC GACGACCTGGCCTTCCGGGACCTCGGCTTCGACTCGCTCACCGTCCTGGAGCTGCGCAAC GCGCTCAACGCCCTCACCGGCCTGAGCCTGCCCGCCTCCCTCGTCTACGACCACCCGACG CCGCGCGAGATGGCGGACTTCCTGCTCGCCGAACTCCTCGGCTCGCTCCCGGAGTCCACC CGCCACGCGGTCGCCACCCGGGCCGTCGACGAGGACCCGATCGCGGTCGTCGGCCTCGCC TGCCGCTTCCCCGGCGGCGTGAGCACGCCCGAGGAGCTGTGGCAGCTGCTGGCGGAGGGC CGCGACGGCATCACCGGCTTCCCCGACGACCGCAACTGGGACATCGCGGCCCTCGGCGCC GGCGCCTCCGACACCCTGCACGGCGGATTCCTCGCCCAGGTCGCCGACTTCGACGCCCGC TTCTTCGGCATCTCGCCCCGCGAGGCGCTCGCCATGGACCCGCAGCAGCGACTGCTGCTC GAGACCACCTGGGAGGCCCTGGAGCGGGCCGGCATCGACCCGGCCGCGCTGCGCGGCTCC ACCACCGGTGTGTTCGTCGGCACCAACGGCCAGGACTACCCGAACCTGCTGCGCCGCTCG ACCTCGGACGTCTCCGGCTATGTCGCCACCGGCAACACCGCCAGCGTGATGTCCGGCCGC CTCTCCTACGCCCTCGGCCTGGAGGGCCCCGCAGTCACCATCGACACCGCCTGCTCCTCC TCGCTGGTCGCCCTGCACTGGGCGGGCCACGCGCTGAGCGCCGGCGAGTGCGACCTCGTC GTCGCGGGCGGCGTCTCGGTGATGTCGACCCCCGACTCCTTCGTCGAGTTCAGCACCCAG GGCGGCCTGGCCCCCGACGGCCACTGCAAGCCGTTCTCCGACGACGCCGACGGCACCGCC TGGTCCGAGGGCGTCGGCATCCTGGTCCTGGAGCGGCTCTCCGACGCGATCCGCAACGGC CACGAGGTCCGCGGCATCATCCGCGGCACCGCCGTCAACCAGGACGGCGCCTCCAACGGA CTGACCGCCCCCAACGGCCCGTCCCAGCAGCGCGTCATCCGCCAGGCCCTCGCGGACGCC CGTCTCGCGCCGTCCGAGATCGACGCGGTCGAGGCGCACGGCACCGGCACCACCCTCGGC GACCCGATCGAGGCGCAGGCCCTCCTCAACACCTACGGCCCGGGCCGGGACACCGACCAG CCGCTGCTGCTCGGCACCGTCAAGTCCAACATCGGCCACACCCAGGCCGCCGCGGGCGTC GCCGGCGTCATCAAGATGCTGCTGGCGATGCAGCACGGCACCCTGCCGCGCACCCTGCAC GTCACCAGCCCCACCAGCCATGTCGACTGGAGCAGCGGCGCGGTGTCGCTGCTCACCGAG GAGCGCGACTGGCCCGAGACCGGACGGCCGAGGCGCGCCGGTGTCTCCGCCTTCGGCGTC AGCGGCACCAATGCGCATGTCATCGTGGAGCAGGCTCCCATCGACGAGCCCGTGGTCGAG CCCACCGAGGAGCCCGCCCCCGCCGCCGAGGTCACCACCGTCCCGTGGATCGTCTCCGGC CGCAGCCGCGAGGCGCTCCAGGACCAGGTCGACCGGCTCACCGCGTACGCCGCCGCCCGC CCGGAGCTCTCCCCGCTGGACGTCGGCCGCTCCCTGGCCACCGACCGCACCCTCTTCCCG CACCGCGCCGTGCTGCTGGCCGGCCCCGACGGGGTGCGCGAGGCGGCTCGTTCGGTCGCG TCCCGCACCCGGGGCCGTACCGCCTTCCTGTTCTCCGGCCAGGGCGCCCAGCGCGCCCTG ATGGGCCGCGAACTCTACGAGCGGTACCCGGCGTTCGCCGACGCGCTGGACACGGTCCTC GCGCAGTTCGACACCGCGCTGGACTTCTCGCTGCGGGAGGTCCTGTTCGCCGAGCCGGGC ACGCCCGAGGCCGAGCGGCTGAACGAGACCGGCTGGACCCAGCCCGCGCTGTTCGCCGTC GAGGTCGCCCTCCACCGCCTCGTGGAGTCGTGGGGCCTGACCCCCGACCAGGTCGCCGGT CACTCCATCGGTGAGATCGCCGCCGCGCATGTCGCCGGGGTGTTCTCGCTGGAGGACGCG TGCGCGCTGGTCGCCGCCCGCGCCTCCCTGATGCAGGAGCTGCCGCGGGGCGGTGCGATG CTCGCGGTGCGCGCCACCGAGGAGGAGGTCGCCCCGCATCTGACGGAGCGCGTCTCCGTC GCGGCGGTCAACGGTCCTTCGGCGGTGGTCGTCGCCGGTGACGAGGCCGAAGTCGCCGCG ATCGCCGCGCACTTCGAGGCGCAGGACCGCAAGACCACCCGGCTGCGGGTGAGCCATGCC TTCCACTCGCCGCTCATGGACCCGATGCTCACCGCCTTCGCCCGGGTCGCGGAGTCCCTC ACCTACCACGAGCCCGTCATCCCGCTGGTCTCCACGGTGACCGGCGTACCCGCCGGAGCC GAACTCCTCACCCCCGGCTACTGGGTGCGGCACGTCCGCGAGACCGTACGGTTCGCCGAC GGCGTCCGGGCGCTGCGCGAGGACGGTGTCACCACCTTCGTCGAGATCGGTCCGGACGGA CAGCTCACCGCCGCCGCCCAGCAGACCCTGGACGCGTCCGGCGACGAGGCACCTGCCACC GTCGTCGCGCTCCAGCGCCGCGACCGCTCCGAGGAGACCACCCTCCTGGAGGGCCTGGCC ACCCTGCACACCCAGGGCGCCGGACCCGACTGGACCGCCTGGTTCGCCGGCACCGGCGGA CACCGCGTCGAACTGCCGACGTACGCCTTCCAGCGCGAGCGCTACTGGCCCGAGCCCGCC GCGCCCGGCGCCACCGGCGTCCAGGACCCCGTCGACGCCGCCTTCTGGGCCGCCGTCGAG CGGGAGGACCTGGAGAGCCTCACGGCCTCCCTGGGCCTGGACGGCGACACCGTCACCACG ATGGTGCCCGCGCTGTCCGCCTGGCGCCGCCGCACCGACGCCCGCTCCACCGCCCGCGAC TGGCGCTACCACGAGAGCTGGACCGCGCTCGGCACCCCGGCGCACTCCGCGGGAGCCGGC CGCGTCCTGGCCCTGGTGCCCGCCGAACACGCCGGCACGGACTGGGCGGAGACCCTGGTC GCCGCCCTGGGCGCCGACCCGCTCGTCGTGGACGGGACCTCCGGCTCCCTCGCCCGGGAA CTCGCGGACCTAGTGCCCCAACAGGCGACGTTCGCCCCGTCGCGACGCCCGGCACGCACT CTCGCCGCACCGGCCGAAAGCCCGAGTACGTCCAGTACGGGGACTTCCGGCCGGCACACC GAGAGCACGCACCGGACGCCGCTCCTGGACGGGCAAACGTCACCTGCCGGGACACTGGAC CCGGCCGGCTGGACCGTCGTGGTCTCGCTGCTCGCCGCGGGCACCGGCACCCTGCCGGCC CCCGACGCCGCACCGGCCGCCGTCCTGGAGGCCCTCGAGGCCGCCGGCGTCGACGCCCCG CTGTGGTGCGTCACCCGCGGCGCCGTCTCCGTCGCCGGGGAGGCACCCGCCGCCGTCGGC CAGGCCGCCCTCTGGGGCATGGGCCGGGTCGCCGCCCTTGAGCACCCCGAGCGCTTCGGC GGCCTCGCCGACCTCGCGCCCGACGCCGACGCCGCCACCGCTGCCCTGCTCGCCGCCCAC CTGGCCGAGCCCGGCGGCGAGGACCAGATCGCCGTCCGCGCCACCGGTCTCTTCGGCCGC CGCCTGGTGCGCACCGCCGTCGCCCCCGGCGACTCCGGATGGCGCCCGCACGGCACCGTC CTGGTCGTCGGCGGCACCCGCGCCATGGGCGCCCGCGCCGCCCGCTGGCTCGCCCGCGAG GGCGCCGCCCGCCTGGTGCTGACCACCTCCCCGGCCGACAGTGCCACCGACACCGAGGAG CTGAGGGCCGAACTCGGCCGGCTCGGCGCCGAGGTCACCGTCGCCCCGTACGACGGCGGC GACCGGGACGCGGCCCGCGCCCTCCTGGACGGACTGACCGGCCTCACCGCGGTCGTGTAC GCCGACGACACCCCGGCGGACGGCCCGGCCGCCGCCCTCGCCCCGGTGGACACCCTCGCC GAGGCCGCCACCGGCCGCTCCCTGGACGCGTTCGTGCTCTTCGGCTCCGTCGCCGGGGTC TGGGGCGTGCGCGGCCACACCGACGAGGCCGCGGAAGGCGCCTATGTGGACGCCCTCGCC CGCGCCCTGCGCGCCGAGGGGACGCCCGCGCTGGCCGTCTCCTGGAACGCCTGGGCCGAG CTGACCGACCCGTCGACCACCCGCCATCTGCGGATGAACGGCCTGCCGGTGATGGACGCC GACGCCGCCCTGACCGCCCTCGCCGGTGCCGTCGCCGACGGCTCCGCCGCGGTCACCGTC GCCGACGTCCGCTGGGACACCTTCGCCCCGGCGCACCACGAGACCCGGCCGACCGCACTC TTCGACGGCCTGCCCGAGGCCAGGACCGCCCTCGCCGGCGCGGCCCGCGACCGTGCCGAG GGGGCCACCGCCTCCGACGGCTACGGCCGGTGGCTCCTGGAGCAGCCCGCCGCCGACCGG GACGACATCCTGCTCGCCCTGGTCAGCGAGAAGGCCGCCTTGGTCCTCGGCCACGCGGAC ACCACGCTCGTCGAACCCGACCTGCCCTTCCGGGACCTCGGCTTCGACTCGCTGACCGCC GTGGACCTGCGCAACCAGCTGACCGCCGCCACCGGCATCACACTGCCCGCGACCCTGGTC TTCGACCACCCCAACCCCGCGGCGCTCGCCGCACACCTGCGCACCGAACTCCTCGGCGGC GCCACGGACACCGCCGCCCCGGTGGCCGCGCCCGCCGCCACCGGCGACGACCCGATCGTC ATCGTCGGCATGGCCTGCCGCTTCCCCGGAGGCGTCAACTCGCCCGAGGACCTCTGGCAG CTCGTCCTCGACGAGGTGGACGCCGTCGGCGACTTCCCGGCCGACCGCGGCTGGGACCTC GACGCCCTGGCCGGCGACGGACCGGGCCGCAGCGCCACCGACCAGGGCGGATTCCTCTAC GACGCCACCGACTTCGACCCCGGTCTGTTCGGTGTCTCGCCGCGCGAGGCCATGGTGATG GACCCGCAGCAGCGGATCCTGCTCGAGGCGTCCTGGGAGGCCCTGGAGCGGGCCGGCATC GACCCCGGCACCCTGCGCGGCAGCGGCACCACCGGCGTCTTCGTCGGCGGCGGCTCCGGC GACTACCGGCCGCCGGCCGAGTACGGCCAGTGGCAGACCGCCCAGTCCGCCAGCCTGCTG TCCGGCCGCCTCGCCTACACCTTCGGCATCCAGGGCCCCACGGTGTCCGTCGACACCGCC TGCTCCTCCTCCCTGGTCGCCCTGCACCTGGCCGCCCAGGCCCTGCGCTCCGGCGAGTGC TCGATCGCCCTGGCCGGCGGTGTCACCGTGATGGCCACCCCGGTCGGCTTCGTCGAGTTC AGCGCCCAGGGCGCGCTGTCGCCCGACGGCCGCTGCCGCGCCTTCTCCGAGGACGCCAAC GGCACCGGCTGGTCGGAGGGTGTCGGCATGCTCGTCGTCGAGCGCCTGTCCGACGCCCGC CGCAACGGCCACCGGGTGCTCGCCGTGCTGCGCGGCTCCGCCATCAACCAGGACGGCGCC TCCAACGGACTGACCGCGCCCAGCGGCCCCGCCCAGCAGCGCGTCATCCGCCAGGCCCTC GCCAACGCCCGCCTGGAGGCCGCCGACGTCGACGCCGTCGAGGCGCACGGCACCGGCACC AAGCTCGGCGACCCGATCGAGGCGCAGGCCCTGCTCGCCACCTACGGGCAGGACCGCGAG CGGCCCGTGCTCGTCGGCTCGCTGAAGGCCAACATCGGCCACACGCAGGCCGCGTCCGGT GTCGGCGGCGTCATCAAGATGGTGCTCGCCATGCAGCACGGTCTGCTGCCGCGCTCGCTG TACACCGAGAACCCCTCCTCGCACGTCGACTGGACCGCGGGCAACGCCCGCCTGCTCACC GAGCTGACCCCCTGGCCCGAGTCGGAGCGGGTGCGCCGGGCCGCCGTCTCCTCCTTCGGG GCCAGCGGCACCAACGCCCACCTGATCCTGGAGCAGCCGGAGCCCGTCAGGCAGCCCGTG GAGGGTGCCCGGCCCGCCGAGGACGGCTCGCCCGTCCCGGTCCTGCTGTCCGGCCGCTCG CAGAACGCGCTGCGCGCCCAGGCCCGCAAGCTTCTGGCCCATGTGGCGGGACACCCCGAG GAGACGGTCACCGACCTGGCCCGCACCCTGGCCACCACCCGCGCCGTCTTCGAGCACCGG GCCGCGGTGACCGCCGCCGACCGGGACGCCCTGATCGCCGGACTCACCGCCGTCGCGGAG GGCACCACCGCCGCGCACATCGTCGAGCACCAGGTGGAGCGCACCGGCAAGCACGCCGTG CTCTTCTCCGGACAGGGCTCCCAGCAGCTCGGCATGGGCCGGGACCTGTACGAGCGGTTC CCGGCGTTCGCCGAGGCGTTCGACGCGGTCCTCGCCCGGCTCGACGGCCACCTCGGCGCC TCGCTGCGGGACGTCGTCTGGCACGGCGACCAGGAGACCCTGAACGAGACCGGGCACACC CAGCCCGCGCTGTTCGCCTTCGAGGTCGCCCTGTACCGCCTGGTGGAGTCCTGGGGAGTG ACGCCGGACTTCGTCGCGGGACACTCCGTCGGCGAGATCGCCGCCGCCCATGTCGCGGGC GTCCTCTCCCTGGACGACGCCTGCCGGCTGGTCGCCGCACGGGCCCGCCTGATGCAGGAC CTGCCGCGCGGCGGCGCCATGGTCGCGGTCGAGGCCACCGAGCAGGAGGTCGCCGCCGAA CTCACCGAGGCGGTGTCGATCGCCGCGGTCAACGGCCCCACCTCCGTGGTGCTCGCCGGT GCGGAGGACGCGGTGCTCGCCGTGGCCGCCGTCCTCGCCGAGCGTGGCCGCCGCACCTCC CGCCTCAAGGTCAGCCACGCCTTCCACTCGGTGCTGATGGACCCGATGCTCGCCGAGTTC CGCAAGGTCGCCGAGAGCCTGCGCTACGAGGCACCCCGCATCGCCGTCGTGTCCAACGTG ACCGGCGACGTGGCGGGCGCCGACGAACTGTGCGACGCCGACTACTGGGTGCGCCATGTG CGCGGCACCGTCCGGTTCGCCGACGGCGTCACCGCACTGGCCGGCCGTGGCGTCCGGGTC CTCCTCGAACTCGGCCCCGACGCGGTGCTGTCCGCGCTGGCCGAGCAGAGCGCCCCGGAC ACCGTGAGCATCCCCGCGCAGCGCCGCAACCGCGACGAGGTGGAGACCCTGGTCGCCGCC CTCGGCCGGCTGCACGTACACGCCGCCGGACCCCGCTGGGACGCCTTCTTCGACGCCGCC CCCGGCTCCTGGCTGGACCTGCCGACCTACGCCTTCCAGCGCGGCCGGTTCTGGCCGGAC ACCCTGCCCACCGCCCCGCAGGGCGGCGCGACCGCAGGGGAGGCCGACGGCACCGACAGC GCCTTCTGGGACGCCGTCGCACAGGAGGACTTCGGCTCGCTGGAGTCCGTCCTCGACGTC GAGGGCGACGCCCTGTCCAAGGTGCTGCCGGCGCTGCTCGACTGGCGTCGCCGCACCTCC GAGGAGACCCAGCTCGACAGCTGGCGCCACCGCATCGTCTGGAAGCGGCTGACCGGCGCG GCGATGGCCCACCGCAAGCCGCTCACCGGCACCTGGCTGGCCGTCGTCCCCGAGGGCCTC GGCGAGGACCCGTGGGTGACGACCGCGCTGGACGCCCTGGGCACCCGGGTGGTGCGCGCC GAGGTCGGCGCCGACGGCCGGGAGGCCATGGCCGCCACCCTGCGGGAGGCCGCCGGGGAG GGCACCCGCTTCGGCGGCGTCGTCTCCCTGCTGGCCCTGCGCGAGACCGTGCACGGCGAT GTGCCGGAGGGCGTCGCCCTCACCGGCACGCTGCTCCAGGCGCTCGGCGACGCCGGGATC GAGGCCCCGCTGTGGTGCGTCACCCGCAGCGCCGTGTCCGCCAACCGCTCCGACCGTCCG CGTCGGCCGCTGCAGGCCGCCGTGTGGGGCCTGGGCCGGGTGGCCGCGCTGGAGTACCCG AACCGCTGGGGCGGTCTGGTGGACCTGCCGGAGCGCGCCGACGAACGGGCCGCCGCCGGA CTCGCCGCCGTCCTCGCCGGACTCGACGGGGAGGACCAGGTCGCCGTGCGCGGCTCCGCC GTCCTCGCCCGCCGCCTGGTGCCGGCCCCGGACCGCGGACAGAGCGGCGCCTGGGACCCG ACCGGCACCGTGCTGATCACCGGCGGCACCGGAGCCATCGGCGCCCATGTGGCCCGCCGA CTGGCCAAGGACGGCGTCCAGCACCTGGTGCTGCTGAGCCGCCGCGGAGCCGAGGCGCCC GGCGCCACCGCCCTGCGCGACGAACTCCAGACGCTCGGCGCCGGCGTCACCCTCGCCGCC TGCGACGCCTCCGACCGGGGCCAGCTGGCCGCGGTGCTGGACGCGATCCCGGACGACCGG CCGCTGACCGCGGTGCTGCACGCGGCGGGCGTGCTCGACGACGGCGTCATCGACCGGCTC ACCCCGGAGCGGTACCAGAAGGTGTTCCGCGCGAAGGTGACCTCGGCGCTGCTCCTCGAC GAGCTGACCCGCGACCTCGACCTGGCCGCGTTCGTCCTGTTCTCGTCCGCCTCCTCCGCG GTCGGCAACCCCGGCCAGGCCAACTACGCGGCGGCCAACGCGGTCCTGGACGCCCTCGCC GAGGCCCGCCGGGTGCAGAACCTGCCCGCGACCTCCGTGTCCTGGGGCGCCTGGGGCGGC GGCGGCATGGCCGACGGCCACGGCGCGGACGACGCGGCCCGCCGGGCCGGCGTCGCCGCC ATGGACCCGGACCTCGCCGTGGAGTCGCTGCTGCGGCTGGTCACCGGCAAGGAGCCGACC GCGGTGGTCGCCGAGGTCGACCTCGACCGGTTCGCCTCCGCCTTCGGCGGCGCCCGGCCG AGCGCCCTGCTGCGGGAGTTCCCCGGCTACCGGGAGACCGTCGCCGCCGCGGCGCCGGCG TCCCCGGAGGGCACCCTCGCCGACCGGCTGGCGGGCATGGCGCCGGCCCGCCGCCTGGAC ACCGTCGTGGACCTGGTACGGACCCGTGCCGCGCAGGTCCTCGGCTACCCGGACATCGAC GCCGTCGGAGCCGAACGGTCCTTCCGGGACCTCGGGGTGGACTCGCTGGGCGCGGTCGAG CTGCGCAACCAGCTCGGCGCCGAGACCGGTCTGAGCCTGCCCGCGACGCTGGTCTTCGAC CACCCGACGCCGCTGGCGCTGGGCGAGTTCGTCCTCGCCCGGCTCGCCCCCGAGGAGGCC GGGCCGGCCGTGTCCGACGAGGAGACCGAGATCAGGGCCGTACTGGCCTCCGTCCCGCTC GACCGACTGCGTGAGATCGGGGTCCTGGAGCCGCTGCTCCAGCTCGCCGGACGCGGTGGT GGGGCCGGCGACGACGAAGACGGCGAGTCCGTCGACTCGATGACAGTGGCAGACCTGGTG CGGGCCGCGCTCAACGGCCAGTCCGACCTGTAG
Feature
| BLASTP Database:UniProtKB:2011_09 |
|
|---|---|
| InterPro Database:interpro:38.0 |
IPR001227 Acyl transferase domain (Domain)
IPR002198 Short-chain dehydrogenase/reductase SDR (Family)
IPR006162 Phosphopantetheine attachment site (PTM)
IPR009081 Acyl carrier protein-like (Domain)
IPR013968 Polyketide synthase, KR (Domain)
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
IPR014043 Acyl transferase (Domain)
IPR015083 Polyketide synthase, docking (Domain)
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
IPR016038 Thiolase-like, subgroup (Domain)
IPR016039 Thiolase-like (Domain)
IPR016040 NAD(P)-binding domain (Domain)
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
IPR020806 Polyketide synthase, phosphopantetheine-binding domain (Domain)
IPR020807 Polyketide synthase, dehydratase domain (Domain)
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain (Domain)
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
|
| SignalP | No significant hit |
| TMHMM | No significant hit |
![[553-684] G3DSA:3.40.366.10](../../img/X2.gif "[553-684] G3DSA:3.40.366.10"){kind=small}
![[2943-3109] 2.99999999999998e-58 PF00106](../../img/H.gif "[2943-3109] 2.99999999999998e-58 PF00106"){kind=small}
![[1707-1722] PS00012](../../img/P.gif "[1707-1722] PS00012"){kind=small}
![[1672-1788] 5.69999708783953e-28 SSF47336](../../img/B.gif "[1672-1788] 5.69999708783953e-28 SSF47336"){kind=small}
![[1679-1749] PS50075](../../img/M.gif "[1679-1749] PS50075"){kind=small}
![[564-861] 3.60002015031011e-123 SM00827](../../img/R.gif "[564-861] 3.60002015031011e-123 SM00827"){kind=small}
