Borre_00330 Borre_00330   Borre_00350 Borre_00350

Borre_00340 : CDS information

close this sectionLocation

Organism
StrainTü4055
Entry nameBorrelidin
Contig
Start / Stop / Direction63,076 / 62,885 / - [in whole cluster]
63,076 / 62,885 / - [in contig]
Locationcomplement(62885..63076) [in whole cluster]
complement(62885..63076) [in contig]
TypeCDS
Length192 bp (63 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category5.2 function unknown
Productputative acetyltransferase(fragment)
Product (GenBank)hypothetical protein
Gene
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)
  • ORFB13a
Reference
ACC
PmId
[15112998] Biosynthesis of the angiogenesis inhibitor borrelidin by Streptomyces parvulus Tu4055: cluster analysis and assignment of functions. (Chem Biol. , 2004)
comment
Borrelidin生合成gene clusterのクローニング。
orfB13: closest similar to putative acetyltransferase

borrelidin生合成に必要な機能や役割をもつタンパクに類似性がない、またはputative functionsがborrelidin生合成のために必要かわからないもの。

---
論文では163aaのorfB13であるが、UniProtでは2つのfragmentsに分かれている。
nt.position 62885でのG deletionによるframeshift.
N-term> Q70HY3: orfB13a(63aa)
C-term> Q70HY4: orfB13b(99aa)
Family/Domain
FD
IPR000182
comment
[IPR000182] GCN5-related N-acetyltransferase (Domain)
function; N-acetyltransferase activity

frameshiftを考慮した全長でhitする。

close this sectionSequence

selected fasta
>putative acetyltransferase(fragment) [hypothetical protein]
MLPVQSSSASVRGEIVIRRAVARDAKRLSRLVRGSRAYEGPYAAMVSDYRVGPDYIENHQ
VFVA
selected fasta
>putative acetyltransferase(fragment) [hypothetical protein]
CTGCTCCCCGTGCAATCGAGTTCCGCGTCCGTACGGGGCGAGATCGTCATCCGCCGGGCG
GTCGCCCGGGACGCCAAGCGGCTCTCGCGTCTCGTACGCGGCTCACGAGCCTACGAGGGC
CCGTACGCGGCGATGGTCTCCGACTACCGCGTCGGGCCCGACTACATCGAGAACCACCAG
GTCTTCGTAGCG

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro No significant hit
SignalP No significant hit
TMHMM No significant hit
Borre_00330 Borre_00330   Borre_00350 Borre_00350
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