MUP_00610 : CDS information

Location

Organism	Mycobacterium ulcerans
Strain	Agy99
Entry name	Mycolactone
Contig	BX649209
Start / Stop / Direction	155,574 / 156,482 / + [in whole cluster] 155,574 / 156,482 / + [in contig]
Location	155574..156482 [in whole cluster] 155574..156482 [in contig]
Type	CDS
Length	909 bp (302 aa)

Annotation

Category
Product
Product (GenBank)	probable transposase for the insertion element IS2606 (fragment)
Gene
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)	MUP061, -, len: 302 aa. Probable IS2606 transposase fragment, highly similar to the C-terminus of Q9ZG97 Probable transposase from Mycobacterium ulcerans (444 aa), fasta scores: opt: 1990, E(): 2.8e-132, (98.675% identity in 302 aa overlap); and to the C-terminus of O05912 Hypothetical 48.7 kDa protein (IS1554, transposase) from M. tuberculosis (439 aa), fasta scores: opt: 1544, E(): 6.9e-101, (75.166% identity in 302 aa overlap). The transposase described here may be made by a frame shifting mechanism during translation that fuses MUP060 and MUP061, no sequence errors have been identified to account for this.

Sequence

>[probable transposase for the insertion element IS2606 (fragment)]
MLSLYARGLTTGEISAHFAHIYDAAVSKDTVSRITDCVLEEMTAWHTRPLERVYAAVFID
ALHVKIRDGQVGPRPVYAAVGVDLAGHRDVLGMWAGEGDGESAKYWLAVLTELKNRGVAD
IFFLVCDGLKGLPDSVSAVFPDTVVQTCIIHLIRGTFRYAGRQHHTAIARALKPIYTAVN
AAAAAEALDAFDTEWGHRYPAAIRLWRNAWNEFIPFLDYDTEIRKVICSTNAIEWLNARY
RRAIRARGHFPTEQSALKCLYLVTRSLDPTGTGQKRWTMRWKPALNAFAITFADRMPGSE
TT

>[probable transposase for the insertion element IS2606 (fragment)]
GTGTTGTCGCTGTATGCCCGCGGGTTGACCACCGGGGAGATCAGCGCCCATTTCGCCCAC
ATCTACGACGCGGCGGTGTCCAAGGACACCGTTAGCCGGATCACCGACTGCGTTCTCGAG
GAGATGACCGCCTGGCATACCCGCCCGCTAGAGCGCGTATACGCCGCGGTGTTCATCGAC
GCCCTGCACGTCAAGATCCGCGACGGCCAAGTCGGCCCCCGGCCGGTCTACGCCGCGGTC
GGGGTCGATCTGGCCGGACACCGTGACGTGCTGGGCATGTGGGCCGGTGAAGGTGACGGC
GAATCGGCCAAGTACTGGCTGGCAGTGCTGACGGAGTTGAAAAACCGCGGCGTGGCCGAC
ATCTTCTTCCTGGTCTGTGACGGCCTCAAAGGACTGCCGGACTCGGTGAGCGCGGTCTTC
CCCGACACCGTGGTGCAAACCTGCATCATCCACTTGATCCGCGGCACGTTCCGCTACGCC
GGGCGCCAGCACCACACCGCGATCGCCCGGGCGCTCAAGCCGATCTACACCGCGGTCAAC
GCTGCTGCGGCCGCCGAAGCCTTAGATGCCTTCGACACCGAATGGGGACACCGCTACCCA
GCGGCAATTCGATTGTGGCGCAACGCCTGGAATGAGTTCATCCCATTCCTGGACTACGAC
ACCGAGATAAGGAAGGTGATTTGTTCGACCAATGCCATTGAATGGCTCAACGCCCGCTAC
CGCCGTGCGATCAGGGCGCGTGGTCATTTCCCCACCGAGCAGTCCGCCCTGAAATGCCTA
TACTTGGTCACCCGGTCGCTAGATCCAACCGGAACCGGACAGAAGCGATGGACGATGCGC
TGGAAACCAGCATTGAACGCCTTCGCGATCACCTTCGCCGACCGCATGCCAGGAAGCGAA
ACCACCTAA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR001207 Transposase, mutator type (Family) PF00872 Transposase_mut PS01007 TRANSPOSASE_MUTATOR
SignalP	No significant hit
TMHMM	No significant hit

MUP_00600 MUP_00620