Nanch_00290 Nanch_00290   Nanch_00310 Nanch_00310

Nanch_00300 : CDS information

close this sectionLocation

Organism
StrainNS3226
Entry nameNanchangmycin
Contig
Start / Stop / Direction102,600 / 103,541 / + [in whole cluster]
102,600 / 103,541 / + [in contig]
Location102600..103541 [in whole cluster]
102600..103541 [in contig]
TypeCDS
Length942 bp (313 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative AraC family transcriptional regulator
Product (GenBank)NanR4
Gene
Gene (GenBank)nanR4
EC number
Keyword
Note
Note (GenBank)
  • probable araC family transcription regulator
Reference
ACC
PmId
[12770825] A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin. (Chem Biol. , 2003)
comment
nanchangmycin生合成のためのcomplete gene clusterの報告。
（complete clusterと言っているが、同定されたclusterがNanchangmycin生合成に十分かは確認されていない。）

配列解析からの機能予測
NanR4: Transcription regulator

nanR4は、AraC family activatorsなどと相同性のあるtranscriptional regulatorをコードしている。
Family/Domain
FD
IPR018060
comment
[IPR018060] Helix-turn-helix, AraC domain (Domain)
function; sequence-specific DNA binding transcription factor activity

close this sectionSequence

selected fasta
>putative AraC family transcriptional regulator [NanR4]
MDPLAGLLDGPRARGAFLLRMVMDPPWSVRIEDRAPLCVMTVARGEAWVVPDRGEARRLG
PGDVAVVRGPDPYTVAGDPATEPQAWILPGEVCRTAGGEDLAERMALGVRTWGNSEHGAT
TMLVGTYRMDGEISRRLLDALPPLLVLGRERCDSPLLPWLGEEIVKEEAGQTAVLDRLLD
LLLISVLRAWFARPEARAPAWYRALGDPVVGRALRLLQNNPGHPWTVALLAAETGISRAV
LARRFTELVGEPPMAYLTGWRLDLAADLLREPDATLGAVARRVGYGSSFALSAAFKRVRG
VSPREHRSAASAG
selected fasta
>putative AraC family transcriptional regulator [NanR4]
ATGGATCCACTCGCCGGTCTCCTGGACGGGCCGAGGGCCCGGGGGGCGTTTCTGCTCCGG
ATGGTGATGGACCCGCCCTGGTCGGTACGGATCGAGGACCGGGCCCCGCTGTGCGTGATG
ACCGTGGCGCGCGGTGAGGCGTGGGTGGTCCCGGACCGGGGCGAAGCGCGGCGCCTTGGC
CCGGGGGATGTGGCGGTCGTGCGCGGCCCCGATCCGTACACCGTGGCCGGCGATCCGGCC
ACCGAGCCCCAGGCGTGGATCCTGCCGGGCGAGGTGTGCCGCACCGCCGGGGGCGAGGAT
CTGGCGGAGCGGATGGCGCTGGGCGTACGCACCTGGGGCAACAGCGAACACGGTGCGACG
ACGATGCTGGTCGGCACGTACCGGATGGACGGGGAGATCAGCCGGCGGCTGCTGGACGCG
CTGCCCCCGCTGCTGGTGCTGGGGCGTGAGCGTTGCGATTCGCCGTTGCTGCCGTGGCTC
GGCGAGGAGATCGTCAAGGAGGAGGCGGGCCAGACGGCCGTGCTGGACCGGCTGCTGGAT
CTGCTGCTGATCTCGGTGCTGCGGGCGTGGTTCGCGCGGCCTGAGGCGCGGGCCCCGGCC
TGGTACCGGGCGCTGGGCGACCCGGTGGTCGGCCGCGCGCTGCGGCTGCTGCAGAACAAC
CCGGGCCATCCGTGGACGGTGGCGCTGCTGGCGGCGGAGACCGGGATCTCCCGTGCGGTG
CTGGCCCGCCGGTTCACCGAGCTGGTCGGCGAGCCGCCGATGGCGTATCTGACCGGCTGG
CGGCTGGATCTGGCCGCCGATCTGCTGCGGGAGCCGGACGCCACCCTCGGGGCGGTGGCC
CGGCGGGTCGGCTACGGCAGCTCCTTCGCGCTGAGCGCCGCCTTCAAGCGGGTGCGCGGG
GTCAGCCCGCGGGAGCACCGCTCCGCGGCCAGCGCAGGGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR009057 Homeodomain-like (Domain)
[207-260] 9.7e-16 G3DSA:1.10.10.60 [261-309] 6.90000000000001e-13 G3DSA:1.10.10.60
G3DSA:1.10.10.60   Homeodomain-rel
[206-257] 4.00000300869883e-10 SSF46689 [260-309] 4.30000170645867e-11 SSF46689
SSF46689   Homeodomain_like
IPR018060 DNA binding HTH domain, AraC-type (Domain)
[211-309] PS01124
PS01124   HTH_ARAC_FAMILY_2
[224-307] 5.00000909915354e-30 SM00342
SM00342   HTH_ARAC
IPR018062 HTH domain AraC-type, conserved site (Conserved_site)
[261-303] PS00041
PS00041   HTH_ARAC_FAMILY_1
SignalP No significant hit
TMHMM No significant hit
Nanch_00290 Nanch_00290   Nanch_00310 Nanch_00310
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