Nysta_00040
Nysta_00050 : CDS information
Location
| Organism | Streptomyces noursei |
|---|---|
| Strain | ATCC 11455 (=NBRC 15452) |
| Entry name | Nystatin |
| Contig | AF263912 |
| Start / Stop / Direction | 5,930 / 34,363 / + [in whole cluster] 5,930 / 34,363 / + [in contig] |
| Location | 5930..34363 [in whole cluster] 5930..34363 [in contig] |
| Type | CDS |
| Length | 28,434 bp (9,477 aa) |
Annotation
| Category | 1.1 PKS |
|---|---|
| Product | polyketide synthase |
| Product (GenBank) | NysI |
| Gene | |
| Gene (GenBank) | nysI |
| EC number | |
| Keyword | |
| Note | |
| Note (GenBank) |
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| Reference |
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PKS/NRPS Module
| 9 |  | malonyl-CoA |
| 10 |  | malonyl-CoA |
| 11 | | methylmalonyl-CoA |
| 12 | | malonyl-CoA |
| 13 |  | malonyl-CoA |
| 14 | | malonyl-CoA |
Sequence
>polyketide synthase [NysI] MDNEQKLRDYLKLATADLRRTRRRVHKLESAAQEPVAIIGMTCRYPGGVRSPEDLWRMVE AGEHGVTPFPTDRGWDLEALAAAPTASGGFLHDAPDFDADFFGISPREAVAMDPQQRVVL ESAWEAFERAGIDPTSVKGSRTGVFIGAMAQDYRVGPADGAEGFQLTGNTGSVLSGRISY TFGTVGPAVTVDTACSSSLVAVHLATQALRAGECTLALAGGVTIMSGPGTFIEMGRQGGL SADGRCRSFGDTADGTGWAEGVGILVLERLSDAVRNGHEILAVVRGTAVNQDGASNGLTA PNGPSQQQVIQQALVNARLAAGDIDVVEAHGTGTTLGDPVEAQALLATYGQNRPADRPLL LGSVKSNLSHTQAAAGVAGVIKMVMAMRHGTLPRTLHAEEPTHHVDWSQGAVRLLTDTTD WPATGAPRRAAVSSFGISGTNAHTIIEQAPEPQPEDAATAQDDAAGSTPATAPVVPGVVP VLLSGRTPDALRGQAAALRAALDTGRRPDLLDLAHSLATTRAGFEHRAVLLATDHPALTD GLTALADADDPAAAPAWITGTTRAETRLAVLFTGQGAQRLGAGRELAARFPAFATALDAA LDAFTPHLDRPLREVLWGTDAALLDRTAYAQPALFAVEVALYRLIESFGVRPDHLAGHSV GEIVAAHLAGVLSLADAATLVAARGRLMQALPDGGAMIAVQASEADVAPLLAGHEDQVAI AAVNGPSAVVLSGAEATVTALAEQLAADGRKTRRLRVSHAFHSPLMEPMLDAFRAVVEDL TLQPPLLPVVSNLTGKPATVAQLTSADYWVDHVRHAVRFADGIDWLARHDTTAFLELGPD GVLSAMAQDCLDAADADAVTLPALRAGRPEEHTLTTALAGLHVHGATLDWTGCFAGTGAR RTDLPTYAFQRRRYWPKALQSGTADLRSVGLGAAHHPLLSAAVSLADAGGTLLTGRLSRQ THPWLADHTVRGTTLLPGTAFLELAVRAGDEVGCDRVEELTLAAPLLLPEQGGVQVQLWI GNPDVSGRRTVNVHARPDTGDDTPWTAHATGVLTTADASRQLPASSEQGGTPLAGDPHPA LDAAQWPPAGAEPLPLDGHYDRLADGGFGYGPVFQGLRAAWRGGDVVYAEVELPEAGRSD AEAFGLHPALLDAALHAAPFTGLGERGRGGLPFSWEGVSLHAGGATTLRVRLTPVADDAL ALTVADGTGAPVLSVDSLVLRSVATQQLDTAAAVARDALFRLDWTPVQPTATDPGPVALL GADPFGLLTHAGFADAPAYPDLAALAAADGPVPTTVVLSLAGTGDDAADPARSAHRCAAE ALAAVQTWLDHHERFAAARLVFVTRGATVGRDVAAAAVWGLVRSAQSENPGCFALVDLDP DGAVGAAALVAALVSGEPQLAVRGDVLRVARLVRRPLTEVGAGADGTGDGVGDGSGVSFS GEGAVLVTGGTGGLGAVLARHLVAEYGVRDLLLVSRSGERAVGAGELVAELAGVGARVRV VACDVTDRAAVVELVGGHAVSAVVHAAGVLDDGMVGALTGERLSAVLRPKVDAVWHLHEA TRGLDLDAFVVFSSLAGVFGSPGQANYAAANAFLDALMTRRRAEGLPGLSLAWGPWEQSG GMTGTLTDVDAERLARSGVPPLSVAQGLALFDAAVAGTDATCVPVRLDLPVLRARGEVPP LLRSLIRVRARRAAVAGSATAGNLAQRLRRLDEDGRDEMVLDLVRGQVALVLGHATGGDV DAGRAFRDLGFDSLTAVELRNRLNTVTGLRLPATLVFDYPTVRHLATYVLDELLGTDAEV ATVQPAAVAVADDPIVIVGMACRYPGGVSSPEDLWRVLTEGTDAVSGFPTNRGWDVESLY HPDPDHPGTSYTRSGGFLHEAGEFDPGFFGMSPREALATDSQQRLLLESSWEAIERAGID PVSLRGSRTGVFAGVMYSDYSAMLASPEFEGFQGSGSSPSLASGRVAYTLGLEGPAVTVD TACSSSLVAMHWAMQALRSGECGLALAGGVTVMSTPAVFVDFARQRGLSPDGRCKAFADA ADGVGWSEGVGVLVLERQSDAVRNGHEILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQ ALASGGLTAGDVDVVEAHGTGTTLGDPIEAQALLATYGRDREPERPLLLGSVKSNLGHTQ AAAGVAGVIKMVLAMRHGVVPRTLHVDAPSSHVDWSEGAVELLSEQAAWPETGRVRRAGV SSFGISGTNVHVIVEQAPGAKAIAAAGAARRTPGAVPVLLSGRGRSALRGQAARLLGHLQ ARPDAELVDVALSLATTRSRFEQRAAVVAQDRDQLIASLGALAADRPDPAVVEGEAAGRG RTAVLFTGQGSQRAAMGRELHEVQPEFAAAFDAVCAVFDPLLDRPLREVVFAEDGSDEAA LLDETGWTQPALFAVEVALFRLVESWGVRPDFVAGHSIGEIAAAHVAGVLTLEDACRLVA ARATLMQALPTGGAMIAIQATEDEIAAHLDDTVAIAAVNGPQSVVISGDEEAAETIAATF AERGRKTKRLRVSHAFHSPRMDGMLDAFRIVAEGLTYRAPRIPLVSDLTGRRADDAEVCT AEYWVRHVREAVRFADCVRTLRDAGATTFLELGSDGLLTAMAEDTLGDDHDAELVPMLRA GRAEELAAATALARLQVRGVDVDWAAYLAGTGARRTDLPTYAFQHAYYWPQLPTPAAALA AADPADQQLWAAVERGDARELADILGLGEQDLTPLDSLLPALTSWRRGNQEKHLLDTLRY RVEWTRLSKPTAPVLDGTWLLVASDATAADQPALLDGLADALGSHGARVRRLLLDDSCAD RAVLAERLARTADVDAATQVLSVLPLDERDADDCPPLTRGLALTVALVQALADTGAQGRL WTATRGAVSTNPADPVTHPVQAAAWGLGRGVALEHPRLWGGLVDLPQVFDERAGQRLAGI LAVKDAPDGEDQVALRATGVSGRRLVRHTVEALPTAAEFTATGTVLITGGTGGLGAEVAR WLARAGAQHLVLTSRRGPDAPGAAELRAELEGYGPSVSVVACDVADRDALAAVLTALPEE LPLTGVVHTAGVGHYGPLDTLSTAEFAGLTAAKLAGAAHLDALLADRELDFFVLFGSIAG VWGSGNQSAYGAANAYLDALALHRRARGLAATSVAWGPWAEAGMAADDAVSETLRRQGLG LLDPAPAMTELRRAVVRQDVTVTVADVDWQRYAPLFTSARPSALIAGLPEVRALAADERT EQDATGASEVVTRVRALAEPEQLRLLTDLVRTESATVLGHSSADAVPEGRAFRDVGFDSL TAVELRKRLGAATGLSLPSTMVFDYPTPLELAQYLRAEILGAVLEVAGPVATGGADDEPI AIIGMACRFPGGVSSPEQLWDLVASGTDAISEFPVNRGWQTGHLFDPDPDRPGTTYSTQG GFLHEADEFDPTFFGISPREALVMDPQQRLLLETTWESFERAGIRPETLRSTLTGTFVGS SYQEYGLGAGDGTEGHMVTGSSPSVLSGRLSYVFGLEGPAVTVDTACSSSLVALHLACQS LRNGESNLAVAGGATIMTTPNPFIAFSRQRALAKDGRCKAFSDDADGMTLAEGVGVVLVE RLSDAQRNGHPVLAVLRGSAINQDGASNGLTAPNGPSQQRVIRQALANARLAPGDIDALE AHGTGTPLGDPIEAQALFATYGRDRDPESALLLGSVKSNIGHTQSAAGIASVIKMVMALR HSELPPTLHADAPSSHVDWSAGTVRLLTQARAWPETGRPRRAAVSSFGISGTNAHVLLEQ APVADTPAEERPAVAPVPIAAGVVPWVVTARSAAALRGQAERLLAHAETVGTALPAAGPL DIGLSLVSARARFEHRAVVVPPAGTDPLAALRAVATDGPSPVVARGVADVEGRTVFVFPG QGSQWVGMGSQLLDESAVFAERIAECAAALAEFTDWSLVDVLRGVVGAPSLERVDVVQPA SFAVMVSLAALWRSRGVLPDAVVGHSQGEIAAAVVSGALSLRDGARVVALRSQAIGRALA GRGGMMSVALSVDVLEPRLVEFEGRVSVAAVNGPRSVVVAGEPEALDALHARLTADDIRA RRIAVDYASHSHQVEDLHEELLEVLAELAPRTSEVPFFSTVTGDWLDTARMDAGYWFRNL RGRVRFADAVADLLAAEYRAFVEVSSHPVLSMAVQEAIDEAGVPAVAAGTLRRDQGGTDR FLLSAAEVFVRGVDVDWAGLFEGTGASRIDLPTYAFQHEHLWAVPPAPEAVAAADPDDAA FWTAVEDGDVSALTAALGTDEDSVAAVLPALTSWRRARRDRSTVDAWRYRVAWKPLGGTL PHPSLTGTWLLVTADGIDDTDVAGALETYGAEVRRLVLDEECVDRAVLRERLAGAEDVTG IVSVLAAAERTDAVPGTSLVLGTALTVALIQALGDAEIDAPVWALTRGAVSTGRADELTA PVQAQVTGIGWTAALEHPQRWGGTLDLPAALDARAAQRLAAVLSGALGSDDQLAIRPSGV FTRRIVRAEATAGRPAGTWTPRGTTLVTGGSGTLAPHLARWLAQRGAEHLVLISRRGTAA PGAAELVAELAESGTEATVAACDITDRDAVAALLADLKADGRTVRTVVHTAATIELHTLD ATTLADFDRVLHAKVTGAQVLAELLDDEELDDFVLYSSTAGMWGSGAHAAYVAGNAYLAA LAEHRRANGLPALSLSWGIWADDLKLGRVDPQMIRRSGLEFMDPQLALSGLQRALDDNEN VLAVADVDWETYHPVYTSGRPTPLFDEVPEVRRLTAAAEQSAGTVAEGEFAAALRALSDA EQQRTLLETVRTEAASVLGLSSAEDLTDQRAFRDVGFDSLTAVGLRNRLASVTGLTLPST MVFDYPNPAALAAYLHGELAGARSAAAGAAAVPTGAPDADDPIAIVGMSCRYPGGVGSAE DLWRIALDEVDAISGFPADRGWDAEGLYDPDPDRPGRTYSVQGGFLRDVAEFDPGFFGIS PREALSMDPQQRLLLETAWEAFEHAGIDPVGQRGSRTGTFVGASYQDYASGVPNSEGSEG HMITGTLSSVLSGRVSYLFGFEGPAVTLDTACSSSLVAMHLACQSLRNGESSLALAGGVS IMSTPMSFVGFSRQRALAEDGRCKAYADGADGMTLAEGVGLVLLERLSDARANGHQVLAV IRGSAVNQDGASNGLTAPNGPSQQRVIRQALANSAVAPGDIDVLEGHGTGTALGDPIEAQ ALLATYGQDRAPERPLLLGSVKSNIGHTQMASGVASVIKLVRALQEGVVPKSLHIDRPST HVDWSSGAIGLLTERTPWPETGRPRRAAVSSFGISGTNVHTILEQAPADEAPTPADPPRD GLVPVLLSGRGEAALRAQAARLLAFVEERPEAHLTDLAHSLATSRAALERRAAVIAADRD TLTRGLRALSDGRPDPGLVQGTAGRGRTAFLFTGQGSQRPGMGRELHDRYPVFADALDEV LARLDDGPDRPLREVLFAAPDSAEAALLDRTGYAQPALFAVEVALFRLLTSWGLTPDYLA GHSVGELAAAHVAGVLSLDDACTLVAARGRLMQALPEGGAMVALEAAEDEVLPLLEGLTD RVSVAAVNGPRSVVVAGVEEDVLLLADLFAADGRRTKRLRVSHAFHSPLMDAMLDDFAAV ARGLTYHPPTIPFVSNVSGGLATAEQVRTPDYWVGHVRAAVRFADGIDWLATQGDVHTFL ELGPDGVLSAMARESLTDPSRTALLPTLRGDRPEEPALVTAVAAAHAHGARVDWSGYFAD HGARRTTLPTYAFQRERYWPDTTAATSAHTPGSALDAEFWAAVERDDVAALAASLDLDDA TVTAMVPALTAWRRRRGEQTELDSWRYRVTWKPRGGATAPAALTGRWLVLVPHDHQDRQD DATAAWAADVETALGTTTVRLTVTTTDRAALAARITEAAGDQGPFSGVLSLLPLATGDAG HPGAPAALTLTTTAVQALGDAGIDAPLWNVTRGAVAVGRAEQVTAPEQAAVWGLGRAVAL ELPARFGGTLDLPATLDGQAARRLRAVLAATDGEDAVALRPSGVFLRRLAHAPAGPDTAR TAFDPAAGTVLITGGTGGIGGHVARRLARDGATHLLLTSRRGPAAPGADALRAELEELGA RVTLAACDAADRDALAALLAELPDDAPLCAVFHTAGVVEDHVVDALTPENFAAVLRAKTV AAHHLHELTADLDLAAFVLFSSTAGVLGAAGQGNYAAANAHLDALAEHRRSHGLTALSVA WGPWAGSGMVADAAELTDRVRRGGFEPLAPEPAVRALLRAIENDDTTVALADIDWERFQR AFAAVRPLPFVADLPETGRATPATATGAATGLRQQLAELPEHERPAAVLDLLRTQVAAVL GHADPRTVEDDHAFRDLGFDSLTILELRNALNAATGLSLPATLVYDLPTPREMADFLLAE LLGTLPTDTAATVASTASPKLSASFEQGGTPFDDPIAVIGIGCRFPGGVTTPEELWQLLD EGRDGISRFPDDRGWDLAALGAGASDTLEGGFLTGVADFDARFFGISPREALAMDPQQRL LLETTWEALERAGIDPTTLRGSTTGVFVGTNGQDYPTLLRRSASDVAGYVATGNTASVMS GRLSYALGLEGPAVTIDTACSSSLVALHWAGRALRAGECDLVVAGGVSVMASPDSFVEFS TQGGLAPDGRCKAFSDAADGTAWSEGVGILVLERLSAARRNGHQVLGLIRGTAVNQDGAS NGLTAPNGLSQQRVIAQALADARLRPADIDAIEAHGTGTTLGDPIEARALITAYGRDRDA ERPLLLGTVKSNIGHTQAAAGAAGVIKMLMAMRHGTLPRTLHVGTPSSHVDWSGGTVALL DDARPWPRTGQPRRAGVSAFGVSGTNAHVVVEQAPETEAPAAPAAEPAPEATPTVVPWVV SGRSREALQAQLDRLTAHTAAHPARSAADVGRSLATDRTLFPHRAVLLAGPDGVREAARA AAPRTPGRTAFLFSGQGAQHALMGHDLYQRFPVYADALDTVLAQFDTVLDVPLRAALFAA PGTPEAALLDQTGFTQPALFAVEVALFRLAESWRLTPDFVAGHSIGEIAAAHVAGVFSLE DACTLVAARASLMQQLPRDGAMVALEATEDEVAPLLTDGVALAAVNGPRSVVVAGAEDAV RAVADRLAADGRRTRRLTVSHAFHSPLMDPMLTDFARVAEGLTYHEPRIPLVSTLLGAPA GAELRTPDYWVRHVRETVRFADGVRALHDAGAGTFVEIGPDGVLTALTQQTLDTVEAGAP AVVVPLQRRDRAGDLALLEGLATLHTHGTGPSWPAYFEATGGHRTDLPTYAFQRERYWPE LGAPVATAPQDPAAWRYHETWAPLPAPEAAAPAGRALVLVPAGNRDTAWMTAVADALGAD TVTAEPDALAEQLTAAGDTPWRVVVSLLAAASEGLPADGAWPAALLATLDEAGVHAPLWC VTRGAVAVAGEAPTAVGQAALWGLGRVAALDHPDRFGGLADLPADTDAHAAGLLAAHLAA PGTEAEIAVRATGVHARRLVRTPAAADGATWLPTGTVLVVGGTGGTGTMGGRAARWLVRE GARHLVLTAPDGTTTAADTEALTAELAALGARITVVDHDPTAPDGFAALLDGLPDDTPLT AVVYAPEADAAPGTAAELSAALAPVTALGAALTGRPLDAFVLFGSIAGLWGVRGRAAEAA SGAYLDAFARACRDRGTPALAVAWGAWADLVGPSLAAHLRMNGLPVMDADTALTALSRAV ADGSAAEAVADVRWETFAPLHHEARRTALFDALPEARGALAEAARDRADRKTAAGDYGRW LAEQPAADHDAILLALVTEKAATVLGHADHDLLEPDLPFRDLGFDSLTAVDLRNQLTAET GLTLPATLVFDHPNPAALAAHLRAQLLGEASDSAAPVAAPVALGADDDAIVIVGMACRYP GGVTSPEDLWQLVGDEVDAVGDFPTDRGWDLAALAGDGPGRSATAQGGFLYDATDFDPGL FGISPREALVMDPQQRILLETSWEALERAGIDPATLRGSGTTGVFVGGGSGDYRPPEEAG QWQTAQSASLLSGRLAYTFGIQGPTVSVDTACSSSLVALHLAAQALRAGECSIALAGGVT VMATPVGFVEFSAQGALSPDGRCRAFSDDANGTGWSEGVGMLVVERLSDARRNGHRVLAV LRGSAINQDGASNGLTAPSGPAQQRVIRQALANARLRPADIDAVEAHGTGTRLGDPIEAQ ALLATYGQDRERPVLLGSLKSNIGHTQAASGVGGVIKMVLAMQHGELPRSLYAENPSSHV DWTAGRAHLLTARTPWPDSGRPRRAAVSSFGASGTNAHAILEQPPREELPARPADDGAPL PFLLSGRSQNALRAQARRLLARLTAHPDTRAADLAYSLATTRAAFEHRAAITATDHDGLR TGLTAVAEGTTAPHTAEHHLQGTGKRAVLFSGQGSQRLGMGRELHERHPVFAEAFDSVLA RLDDRLDTPLRDVVWGTDEEALHATGNTQPALFAVEVALYRLIESWGVRPDFVAGHSVGE LAAAHVAGVLSLDDACRLVAARAALMQRLPAGGAMIAVEATEDEVTPLLTDGVSLAAVNG PTAVVLSGAGDAVTALGQALAERGHRTTRLRVSHAFHSHLMDPMLADFRTVAEGLEYHPP RIPVVSNLTGDVADAADLCSADYWVRHVRGTVRFADGVRTMADRGVHLFLELGPDAVLSA MARQCAPDAVVVPALRRNRDEDETLVGAVARLHVHGAGPRWDAYFAGRGAQWLDLPTYPF QRGRFWPESLPGAASAAPAAGQPAETDAAFWDAVAQEDFTALESVLDVESDALSKVLPAL MDWRSRQADESQLAGWRHRIVWKRLTGAALAHRKALSGTWLAVVPEGFADDPWVTTTLDG LGTHLVHLEVAEADRAALADAIAARTADGTRFGGVISLLALREELTGAVPEGTALTTTLL QALGDAGVDAPLWCVTRSAVSAGRTDRPHRPLQGAVWGLGRVAALEYPQRWGGLVDLPEE PDERSAAGLAAVLAGLDGEDQVAVRGTAVLARRLVPAPGRKPSRPWHPSGTVLVTGGTGA LGAHVARRLAKDGAQHLVLLSRRGPDAPGAAELRAELDALGTDVTVAACDVADRDQLTAV LDALPADRPLTGVVHTAGVLDDGVLDRLTPERFQEVFRAKVTSALLLDELTRDRELAAFV LFSSASAAVGNPGQANYAAANAVLDALAEQRRVLGLPATSVSWGAWGGGGMADADGADEA ARRAGVGAMDPHLAVEALLRLVAEKEPTAVVAEVALDRFAGAFGGSRPSALLREFPGYRE ALAAQAEQAADGGGLAARLAALPPARRLDTVVDLVRTRAAQVLGYPDTEAVAAERSFRDL GVDSLGAVELRNQLSAATGLNLPATLVFDHPTPLVLGEHILGGLFPDEPAGSDDETEIRA LLASVPLDQLREIGVLEPLLQLAGRGGRAADGDDGESVDSMTVADLVRAALNGQSDL
>polyketide synthase [NysI] ATGGACAACGAACAAAAACTCCGGGATTACCTCAAGCTTGCGACGGCCGACCTTCGACGC ACCCGGCGGCGCGTCCACAAGCTGGAGTCGGCGGCCCAGGAACCGGTGGCCATCATCGGC ATGACCTGTCGCTACCCCGGCGGCGTCCGCAGCCCCGAAGACCTCTGGCGCATGGTCGAG GCCGGCGAGCACGGCGTCACCCCGTTCCCCACCGACCGCGGTTGGGACCTGGAGGCGCTG GCCGCCGCGCCGACCGCCTCCGGCGGATTCCTGCACGACGCACCCGACTTCGACGCGGAC TTCTTCGGCATCTCGCCGCGCGAGGCGGTCGCCATGGACCCGCAACAGCGCGTCGTCCTG GAATCCGCCTGGGAGGCGTTCGAACGCGCCGGCATCGACCCGACGTCCGTGAAGGGCAGC CGCACCGGAGTCTTCATCGGCGCGATGGCCCAGGACTACCGGGTCGGCCCCGCCGACGGC GCCGAGGGCTTCCAACTCACCGGCAACACCGGCAGCGTGCTGTCCGGCCGCATCTCCTAC ACCTTCGGCACGGTCGGCCCCGCCGTCACCGTCGACACCGCCTGCTCCTCCTCCCTCGTC GCCGTCCACCTCGCCACCCAGGCGCTGCGGGCCGGCGAGTGCACCCTCGCCCTCGCCGGC GGCGTCACCATCATGTCCGGCCCCGGCACCTTCATCGAAATGGGCCGCCAGGGCGGGCTC TCCGCCGACGGCCGCTGCCGCTCCTTCGGCGACACCGCCGACGGCACCGGCTGGGCCGAA GGCGTCGGCATCCTCGTCCTGGAACGGCTGTCCGACGCCGTCCGCAACGGCCACGAGATC CTCGCCGTCGTCCGCGGCACCGCCGTCAACCAGGACGGCGCCTCCAACGGCCTGACCGCC CCCAACGGCCCCTCCCAGCAGCAGGTCATCCAGCAGGCCCTGGTCAACGCCCGACTCGCC GCCGGGGACATCGACGTCGTCGAGGCGCACGGCACCGGCACCACCCTCGGCGACCCCGTC GAGGCCCAGGCCCTGCTCGCCACCTACGGGCAGAACCGCCCGGCGGACCGGCCGCTGCTG CTGGGCTCGGTCAAGTCCAACCTCAGCCACACCCAGGCCGCCGCCGGCGTCGCCGGCGTG ATCAAGATGGTCATGGCGATGCGGCACGGCACCCTGCCGCGCACCCTGCACGCCGAGGAG CCCACCCACCACGTCGACTGGTCGCAGGGCGCCGTGCGGCTGCTGACCGACACCACCGAC TGGCCCGCCACCGGGGCGCCGCGCCGCGCCGCCGTCTCCTCCTTCGGCATCAGCGGCACC AACGCCCACACCATCATCGAGCAGGCCCCCGAACCGCAGCCCGAGGACGCCGCGACCGCG CAGGACGACGCCGCCGGCAGCACGCCGGCCACCGCCCCCGTAGTGCCCGGCGTCGTACCG GTCCTGCTCTCCGGCCGCACCCCGGACGCCCTGCGCGGCCAGGCCGCGGCCCTGCGCGCC GCCCTCGACACCGGCCGGCGGCCCGACCTGCTCGACCTCGCACACTCCCTCGCCACCACC CGCGCCGGGTTCGAGCACCGCGCCGTCCTCCTCGCCACCGACCACCCCGCCCTGACCGAC GGCCTCACCGCCCTCGCCGACGCCGACGACCCGGCCGCCGCCCCCGCCTGGATCACCGGC ACCACCCGGGCCGAGACCCGGCTCGCCGTCCTGTTCACCGGCCAGGGCGCCCAACGCCTC GGCGCGGGACGGGAACTCGCCGCCCGTTTCCCGGCGTTCGCCACCGCCCTCGACGCGGCG CTCGACGCCTTCACCCCGCACCTCGACCGCCCCCTGCGCGAGGTCCTGTGGGGCACCGAC GCCGCCCTGCTCGACCGCACCGCATACGCCCAGCCGGCCCTCTTCGCCGTCGAAGTGGCG CTCTACCGGCTGATCGAATCGTTCGGCGTCCGCCCCGACCACCTCGCCGGCCACTCCGTC GGCGAGATCGTCGCCGCGCACCTCGCCGGGGTCCTCTCCCTGGCCGACGCCGCCACCCTC GTCGCCGCCCGCGGTCGCCTGATGCAGGCGCTGCCCGACGGCGGGGCGATGATCGCCGTC CAGGCGTCGGAAGCCGACGTCGCCCCGCTGCTCGCCGGGCACGAGGACCAGGTCGCGATC GCCGCCGTCAACGGCCCCTCCGCCGTCGTCCTGTCCGGCGCCGAAGCCACCGTCACCGCG CTCGCCGAACAGCTCGCCGCCGACGGCCGCAAGACCCGCCGGCTGCGCGTCTCGCACGCC TTCCACTCGCCGCTCATGGAGCCGATGCTCGACGCCTTCCGCGCCGTCGTCGAAGACCTC ACGCTCCAGCCGCCGCTCCTGCCGGTCGTCTCCAACCTGACCGGCAAGCCCGCCACCGTC GCCCAACTCACCTCCGCCGACTACTGGGTCGACCACGTCCGGCACGCCGTCCGCTTCGCC GACGGCATCGACTGGCTCGCCCGGCACGACACCACCGCCTTCCTCGAACTCGGCCCCGAC GGCGTGCTGTCCGCCATGGCCCAGGACTGCCTGGACGCCGCCGACGCAGACGCCGTCACC CTCCCCGCCCTGCGCGCCGGGCGCCCCGAGGAGCACACCCTCACCACCGCCCTCGCCGGT CTGCACGTCCACGGCGCCACCCTGGACTGGACCGGCTGCTTCGCCGGCACCGGCGCCCGC CGCACCGACCTGCCGACCTACGCCTTCCAGCGCCGCCGCTACTGGCCCAAGGCCCTCCAG AGCGGCACCGCCGACCTGCGCTCGGTCGGCCTCGGTGCCGCCCACCACCCGCTGCTCTCC GCCGCCGTCTCCCTCGCCGACGCAGGCGGCACCCTGCTCACCGGCCGCCTCTCCCGGCAG ACCCACCCCTGGCTCGCCGACCACACCGTCCGCGGCACCACCCTGCTGCCCGGTACCGCC TTCCTCGAACTCGCCGTCCGCGCCGGCGACGAGGTCGGCTGCGACCGCGTCGAGGAACTC ACCCTCGCCGCACCGCTCCTGCTGCCCGAACAGGGCGGCGTCCAGGTCCAGTTGTGGATC GGCAACCCCGACGTGTCCGGTCGCCGCACCGTCAACGTCCACGCCCGCCCCGACACCGGC GACGACACCCCCTGGACCGCCCACGCCACCGGCGTCCTCACCACCGCCGACGCCTCCCGC CAGCTCCCGGCTTCGTCCGAGCAGGGCGGCACCCCCCTCGCCGGCGACCCCCACCCCGCC CTCGACGCGGCCCAGTGGCCCCCGGCCGGCGCCGAACCGCTGCCGCTGGACGGCCACTAC GACCGCCTCGCCGACGGCGGCTTCGGCTACGGCCCGGTCTTCCAGGGCCTGCGCGCCGCC TGGCGCGGCGGCGACGTCGTCTACGCCGAGGTCGAGCTGCCCGAGGCCGGCCGGTCCGAC GCCGAGGCGTTCGGCCTCCACCCCGCCCTGCTCGACGCCGCCCTGCACGCCGCGCCCTTC ACCGGCCTCGGCGAACGCGGCCGGGGCGGCCTGCCGTTCTCCTGGGAGGGCGTCTCCCTC CACGCCGGCGGCGCCACCACCCTCCGCGTCCGCCTGACCCCGGTCGCCGACGACGCGCTC GCCCTGACCGTCGCCGACGGCACCGGCGCGCCCGTGCTGTCCGTCGACTCGCTCGTCCTG CGCAGCGTGGCGACCCAACAGCTCGACACGGCCGCCGCCGTCGCCCGTGACGCCCTCTTC CGCCTCGACTGGACCCCCGTCCAGCCGACCGCCACCGACCCCGGGCCCGTCGCCCTCCTC GGCGCCGACCCCTTCGGCCTGCTCACCCACGCCGGATTCGCCGACGCCCCGGCATACCCG GACCTCGCCGCCCTCGCCGCGGCGGACGGCCCGGTCCCGACCACCGTCGTGCTGTCCCTC GCCGGCACCGGGGACGACGCGGCCGACCCGGCCCGGTCCGCACACCGCTGCGCCGCGGAG GCCCTCGCCGCCGTACAGACCTGGCTCGACCACCATGAGCGCTTCGCCGCCGCCCGCCTG GTCTTCGTGACCCGTGGTGCGACGGTCGGGCGTGATGTTGCTGCTGCTGCGGTGTGGGGT CTGGTGCGTTCGGCGCAGTCGGAGAATCCGGGGTGTTTTGCTCTGGTCGATCTGGATCCG GATGGTGCGGTGGGTGCGGCTGCGCTCGTCGCTGCGTTGGTCAGTGGTGAGCCGCAGCTT GCGGTGCGCGGTGATGTGTTGCGGGTCGCGCGTCTGGTGCGGCGGCCGCTCACCGAGGTC GGTGCGGGTGCTGATGGCACCGGGGATGGCGTCGGGGATGGCTCTGGTGTGTCGTTCTCG GGTGAGGGTGCGGTCCTGGTCACTGGTGGTACGGGTGGTCTGGGTGCGGTGTTGGCGCGT CATCTGGTGGCCGAGTATGGGGTGCGGGATCTGCTGTTGGTCAGTCGCAGTGGTGAACGT GCCGTGGGTGCTGGGGAGTTGGTGGCGGAGCTTGCGGGTGTGGGTGCGCGGGTGCGGGTG GTTGCGTGTGATGTGACCGATCGTGCCGCGGTGGTGGAGTTGGTTGGCGGGCATGCGGTG TCCGCGGTGGTTCATGCGGCTGGTGTGCTGGATGACGGCATGGTGGGTGCGTTGACCGGG GAGCGGTTGTCCGCGGTGCTGCGGCCGAAGGTGGATGCTGTCTGGCATCTACATGAGGCG ACCCGCGGCCTGGACCTGGACGCGTTCGTCGTCTTCTCCTCCCTCGCCGGGGTCTTCGGC AGTCCCGGCCAGGCCAACTACGCGGCCGCGAACGCCTTCCTGGACGCGCTGATGACGCGG CGCCGGGCGGAGGGACTGCCCGGCCTGTCACTCGCATGGGGACCGTGGGAGCAGTCGGGC GGAATGACGGGCACCCTGACGGACGTCGACGCCGAACGGCTGGCCCGCTCCGGTGTCCCG CCGCTCTCCGTGGCGCAGGGCCTGGCCCTCTTCGACGCTGCCGTGGCCGGGACCGACGCC ACCTGCGTTCCGGTCCGCCTGGACCTCCCCGTCCTCCGCGCACGGGGTGAAGTGCCGCCG CTGCTGAGGTCGTTGATCCGCGTCCGGGCGCGCCGAGCCGCCGTCGCCGGCTCCGCCACC GCGGGCAACCTCGCCCAGCGCCTGCGCCGCCTGGACGAGGACGGCCGCGACGAGATGGTC CTGGACCTCGTCCGCGGTCAGGTCGCCCTCGTCCTCGGCCACGCGACCGGTGGCGACGTC GACGCCGGCCGTGCCTTCCGCGACCTCGGCTTCGACTCGCTGACCGCCGTCGAACTGCGC AACCGCCTCAACACCGTCACCGGCCTGCGCCTGCCCGCCACCCTGGTCTTCGACTACCCG ACCGTCCGGCACCTCGCCACGTACGTCCTGGACGAGTTGTTGGGCACGGATGCCGAGGTG GCGACCGTGCAGCCGGCCGCGGTTGCGGTGGCGGACGATCCGATCGTCATCGTGGGCATG GCCTGCCGCTACCCCGGTGGCGTCAGCTCCCCCGAGGACCTGTGGCGCGTGCTCACCGAA GGCACCGACGCCGTCTCGGGCTTCCCGACCAACCGTGGTTGGGACGTCGAATCCCTCTAT CACCCGGACCCTGACCACCCGGGTACCTCCTACACGCGCTCGGGTGGGTTCCTGCATGAG GCGGGGGAGTTCGATCCGGGGTTCTTCGGGATGAGTCCGCGGGAGGCGTTGGCGACCGAT TCCCAGCAGCGGTTGTTGTTGGAGTCGTCGTGGGAGGCGATCGAGCGGGCCGGTATTGAT CCGGTGAGTTTGCGGGGTAGTCGGACGGGTGTGTTCGCGGGGGTGATGTACAGCGATTAC AGCGCGATGTTGGCGAGTCCGGAGTTCGAGGGTTTCCAGGGCAGTGGGAGTTCGCCGAGT TTGGCGTCGGGTCGGGTGGCCTACACGTTGGGGTTGGAAGGCCCGGCGGTGACGGTGGAT ACGGCGTGTTCGTCGTCGTTGGTGGCGATGCACTGGGCGATGCAGGCGTTGCGTAGTGGT GAGTGTGGGTTGGCGTTGGCCGGTGGTGTGACGGTGATGTCGACGCCTGCGGTGTTTGTG GACTTTGCTCGGCAGCGGGGTTTGTCGCCGGATGGCCGGTGCAAGGCGTTTGCGGATGCG GCCGATGGTGTGGGCTGGTCCGAGGGCGTCGGCGTGTTGGTCCTGGAGCGGCAGTCGGAC GCGGTGCGCAATGGTCACGAGATTTTGGCTGTGGTGCGGGGTTCGGCGGTCAACCAGGAT GGTGCGTCCAATGGTTTGACGGCGCCCAATGGTCCGTCGCAGCAGCGGGTGATCCGGCAG GCGTTGGCCAGTGGTGGTCTGACGGCCGGTGACGTGGATGTGGTGGAGGCGCATGGTACG GGTACGACGCTCGGTGATCCGATCGAGGCGCAGGCGTTGTTGGCGACGTATGGGCGGGAT CGTGAGCCTGAGCGGCCGTTGTTGTTGGGTTCGGTGAAGTCGAATCTGGGGCATACGCAG GCTGCTGCGGGTGTGGCGGGCGTTATCAAGATGGTGTTGGCGATGCGGCATGGTGTGGTG CCGCGGACGTTGCATGTGGATGCGCCTTCTTCGCATGTGGACTGGTCCGAGGGTGCGGTG GAGCTGCTCAGTGAGCAGGCGGCCTGGCCGGAGACGGGTCGGGTGCGGCGGGCGGGTGTC TCCTCCTTCGGCATCAGCGGTACCAATGTGCATGTCATCGTCGAGCAGGCGCCGGGCGCC AAGGCGATCGCCGCGGCCGGTGCGGCGCGGCGCACGCCGGGTGCCGTGCCGGTGCTGCTC TCGGGGCGTGGCCGGAGTGCCCTGCGGGGCCAGGCCGCCCGCCTGCTCGGACACCTCCAG GCCCGACCCGACGCCGAACTCGTCGATGTCGCACTGTCGTTGGCGACCACCCGGTCCCGC TTCGAGCAGCGGGCCGCCGTCGTGGCGCAGGACCGCGACCAGCTGATCGCCTCGCTGGGG GCGCTGGCCGCCGACCGCCCCGACCCCGCCGTCGTCGAGGGCGAGGCCGCCGGACGCGGC CGGACCGCGGTGCTGTTCACCGGACAGGGCAGCCAGCGGGCCGCCATGGGGCGTGAACTC CACGAGGTGCAGCCGGAGTTCGCCGCGGCGTTCGACGCGGTGTGTGCCGTTTTCGACCCG CTGTTGGACCGGCCGCTGCGCGAGGTGGTGTTCGCCGAGGACGGCAGCGACGAGGCCGCA CTGCTGGACGAGACCGGTTGGACGCAGCCGGCTCTGTTCGCCGTCGAGGTGGCGCTGTTC CGGCTGGTGGAGAGTTGGGGTGTCCGTCCGGACTTCGTGGCCGGCCATTCCATCGGTGAG ATCGCGGCGGCGCACGTCGCCGGGGTGCTGACGTTGGAGGACGCCTGCCGTCTGGTGGCC GCGCGGGCGACGCTGATGCAGGCGCTGCCGACCGGCGGCGCGATGATCGCGATCCAGGCC ACCGAGGACGAGATCGCGGCGCACCTCGACGACACGGTGGCGATCGCCGCCGTCAACGGG CCGCAGTCCGTGGTGATCTCCGGTGACGAGGAGGCCGCCGAAACGATCGCCGCCACGTTC GCCGAACGCGGGCGCAAGACCAAGCGGCTGCGGGTGAGCCATGCCTTCCACTCGCCGCGG ATGGACGGGATGCTGGACGCCTTCCGGATCGTCGCCGAGGGGCTGACCTACCGGGCGCCG CGCATCCCGCTCGTCTCCGACCTCACCGGCCGGCGCGCCGACGATGCGGAGGTGTGCACC GCGGAGTACTGGGTGCGGCACGTCCGAGAGGCCGTGCGGTTCGCCGACTGCGTGCGGACG CTGCGCGACGCCGGGGCCACCACCTTCCTGGAACTGGGCTCCGACGGCCTGCTGACCGCG ATGGCCGAGGACACCCTCGGTGACGACCACGACGCCGAACTGGTGCCGATGCTGCGCGCC GGGCGCGCCGAGGAACTGGCCGCGGCCACCGCCCTGGCCCGCCTCCAGGTGCGCGGCGTG GACGTGGACTGGGCGGCGTACCTCGCCGGCACCGGCGCCCGACGCACCGACCTGCCGACC TACGCCTTCCAGCACGCGTACTACTGGCCGCAGCTGCCGACCCCGGCCGCCGCCCTCGCC GCCGCCGATCCCGCCGACCAGCAGCTGTGGGCCGCTGTGGAGCGCGGCGACGCCCGCGAA CTCGCCGACATCCTCGGCCTGGGCGAACAGGACCTCACGCCGCTGGACTCCCTGCTGCCC GCCCTCACCTCGTGGCGGCGCGGCAACCAGGAGAAGCACCTCCTGGACACCCTGCGCTAC CGCGTGGAGTGGACACGACTGAGCAAGCCGACCGCCCCGGTCCTCGACGGCACCTGGCTG CTGGTCGCCTCCGACGCCACCGCGGCCGACCAGCCAGCCCTCCTCGACGGCCTGGCCGAC GCCCTCGGCTCGCACGGCGCGCGGGTGCGTCGCCTGCTTCTGGACGACTCCTGCGCGGAC CGCGCGGTGCTCGCCGAACGACTGGCGCGGACCGCCGACGTGGACGCCGCGACCCAGGTG CTGTCCGTGCTGCCGCTCGACGAGCGGGACGCCGACGACTGCCCGCCGCTCACCCGCGGA CTGGCGCTGACCGTCGCGCTCGTCCAGGCCCTCGCCGACACCGGCGCCCAGGGCCGGCTG TGGACCGCCACCCGCGGCGCCGTCTCCACCAACCCCGCCGACCCGGTCACCCACCCCGTC CAGGCCGCTGCCTGGGGCCTGGGCCGGGGCGTCGCCCTGGAGCACCCACGGCTGTGGGGC GGCCTGGTCGACCTGCCGCAGGTCTTCGACGAGCGGGCCGGACAGCGGCTCGCCGGGATC CTCGCCGTCAAGGACGCACCGGACGGCGAGGACCAGGTGGCGCTGCGGGCCACCGGAGTC TCCGGCCGCCGGCTCGTCCGCCACACCGTCGAAGCGCTGCCCACGGCCGCGGAGTTCACC GCCACCGGCACTGTCCTGATCACTGGTGGCACCGGTGGCCTGGGCGCCGAGGTCGCCCGG TGGCTGGCCCGCGCCGGCGCCCAGCACCTCGTCCTGACCAGCCGCCGCGGCCCGGACGCG CCGGGCGCCGCCGAACTCCGGGCCGAACTGGAGGGCTACGGGCCGTCGGTGTCCGTCGTC GCCTGCGACGTCGCCGACCGGGACGCGCTCGCCGCCGTCCTCACCGCACTGCCCGAGGAA CTGCCGCTGACCGGTGTCGTGCACACCGCAGGCGTCGGCCACTACGGCCCGCTGGACACC CTGAGCACCGCCGAGTTCGCCGGCCTCACCGCCGCCAAGCTCGCCGGCGCCGCCCACCTC GACGCCCTGCTCGCCGACCGCGAACTGGACTTCTTCGTCCTCTTCGGCTCCATCGCCGGT GTCTGGGGCAGTGGCAACCAGAGCGCCTACGGCGCCGCCAACGCCTACCTCGACGCGCTC GCCCTGCACCGCCGCGCCCGCGGCCTCGCCGCGACCTCCGTCGCCTGGGGCCCGTGGGCC GAGGCCGGCATGGCCGCCGACGATGCCGTTTCCGAGACCCTGCGCCGCCAGGGCCTCGGC CTGCTCGACCCGGCCCCGGCCATGACCGAGCTGCGCCGCGCCGTCGTCCGGCAGGACGTC ACCGTCACCGTCGCCGACGTGGACTGGCAGCGCTACGCACCGCTGTTCACCTCCGCCCGG CCCAGCGCCCTGATCGCCGGCCTGCCCGAGGTCCGCGCCCTCGCCGCCGACGAGCGCACC GAGCAGGACGCCACCGGCGCCTCCGAGGTCGTCACCCGCGTCCGCGCCCTGGCCGAACCC GAGCAACTGCGCCTGCTGACCGACCTCGTCCGCACCGAGTCCGCCACCGTCCTCGGCCAC AGCTCCGCCGACGCCGTGCCCGAGGGCCGCGCCTTCCGCGACGTCGGCTTCGACTCGCTG ACCGCGGTCGAGCTCCGCAAGCGCCTGGGCGCCGCGACCGGGCTGTCCCTGCCCAGCACC ATGGTCTTCGACTACCCGACACCGCTGGAACTCGCCCAGTACCTGCGGGCGGAGATCCTC GGCGCGGTGCTGGAAGTCGCCGGCCCGGTCGCCACCGGCGGCGCCGACGACGAGCCGATC GCCATCATCGGCATGGCCTGCCGCTTCCCCGGCGGCGTCAGCTCCCCGGAACAGCTGTGG GACCTGGTCGCCTCCGGCACCGACGCGATCAGCGAGTTCCCCGTCAACCGCGGCTGGCAG ACCGGGCACCTCTTCGACCCGGACCCCGACCGGCCCGGCACCACCTACTCCACCCAGGGC GGCTTCCTCCACGAGGCCGACGAGTTCGACCCCACCTTCTTCGGCATCTCGCCCCGCGAG GCGCTGGTCATGGACCCGCAGCAGCGGCTCCTGCTGGAGACCACCTGGGAGTCCTTCGAG CGCGCCGGGATCCGCCCGGAAACCCTCCGATCCACCCTGACCGGCACCTTCGTCGGCTCC AGCTACCAGGAGTACGGCCTGGGCGCGGGCGACGGCACCGAGGGCCACATGGTCACCGGC AGCAGCCCCAGTGTGCTCTCCGGCCGACTGTCGTACGTCTTCGGTCTGGAAGGCCCGGCG GTCACCGTCGACACCGCCTGCTCGTCCTCGCTCGTGGCGCTGCACCTGGCCTGCCAGTCG CTGCGCAACGGCGAGAGCAACCTGGCCGTCGCCGGCGGCGCCACGATCATGACGACGCCC AACCCGTTCATCGCGTTCAGCCGGCAGCGCGCCCTCGCCAAGGACGGCCGCTGCAAGGCG TTCTCCGACGACGCGGACGGCATGACGCTCGCCGAGGGCGTCGGCGTCGTCCTCGTCGAG CGGCTCTCCGACGCGCAGCGCAACGGCCACCCGGTCCTGGCCGTCCTCCGCGGCTCCGCC ATCAACCAGGACGGCGCCTCCAACGGCCTGACCGCGCCCAACGGCCCGTCCCAGCAGAGG GTCATCCGCCAGGCCCTCGCCAACGCCCGCCTCGCGCCCGGGGACATCGACGCCCTGGAG GCGCACGGCACCGGCACACCGCTCGGCGACCCCATCGAGGCCCAGGCACTGTTCGCCACC TACGGCCGCGACCGCGACCCCGAGAGCGCGCTGCTGCTCGGCTCGGTGAAGTCCAACATC GGCCACACCCAGTCCGCCGCGGGCATCGCCAGCGTCATCAAGATGGTCATGGCGCTGCGC CACTCCGAACTGCCGCCGACCCTGCACGCCGACGCGCCGTCCTCGCACGTGGACTGGTCG GCCGGGACGGTCCGGCTGCTGACCCAGGCGCGCGCCTGGCCGGAGACCGGTCGCCCGCGC CGGGCCGCGGTGTCCTCGTTCGGCATCAGCGGTACCAACGCCCATGTCCTGCTGGAGCAG GCGCCCGTCGCGGACACCCCGGCCGAGGAGCGGCCCGCCGTGGCGCCGGTCCCGATCGCC GCCGGCGTCGTCCCGTGGGTGGTCACCGCCCGCAGCGCCGCCGCCCTGCGCGGCCAGGCC GAGCGCCTCCTCGCGCACGCCGAAACCGTCGGAACCGCCCTGCCGGCCGCCGGACCGCTC GACATCGGCCTGTCGCTGGTCTCCGCGCGCGCCCGTTTCGAGCACCGTGCCGTCGTCGTC CCGCCCGCGGGCACCGACCCGCTGGCCGCGCTGCGCGCCGTCGCGACGGACGGGCCCTCG CCCGTGGTCGCCCGTGGCGTGGCGGACGTCGAGGGTCGGACGGTGTTCGTGTTCCCCGGT CAGGGTTCGCAGTGGGTGGGGATGGGGTCCCAACTCCTTGATGAGTCGGCGGTGTTCGCG GAGCGGATTGCCGAGTGTGCGGCGGCACTCGCCGAGTTCACCGACTGGTCGCTGGTCGAT GTGCTGCGGGGTGTGGTGGGTGCGCCGTCGTTGGAGCGGGTCGATGTGGTGCAGCCGGCG TCGTTCGCGGTGATGGTGTCGTTGGCTGCGTTGTGGCGTTCCCGTGGTGTGTTGCCGGAT GCGGTGGTGGGGCATTCGCAGGGTGAGATCGCTGCTGCGGTGGTGTCGGGTGCGCTGTCG TTGCGGGACGGGGCGCGGGTGGTGGCGCTGCGGAGTCAGGCCATTGGTCGTGCGTTGGCG GGGCGGGGAGGGATGATGTCCGTCGCGCTGTCGGTGGACGTGCTCGAACCGCGGTTGGTC GAGTTCGAGGGGCGGGTGTCGGTGGCCGCCGTCAACGGCCCGCGCTCCGTCGTGGTCGCC GGCGAGCCCGAGGCGCTGGACGCGCTGCACGCCCGGCTGACCGCCGACGACATCCGGGCC CGCCGGATCGCGGTGGACTACGCCTCGCACTCGCACCAGGTCGAGGACCTGCACGAGGAA CTGCTGGAGGTGCTGGCGGAGCTGGCGCCGCGCACGTCGGAGGTGCCGTTCTTCTCGACC GTGACCGGCGACTGGCTGGACACCGCGCGGATGGACGCCGGCTACTGGTTCCGCAACCTG CGCGGACGGGTGCGGTTCGCGGACGCGGTGGCGGACCTGCTGGCGGCGGAGTACCGCGCA TTCGTCGAGGTCAGCTCGCACCCGGTGCTGTCGATGGCGGTGCAGGAGGCGATCGACGAG GCCGGCGTGCCGGCCGTCGCCGCCGGCACCCTGCGCCGCGACCAGGGCGGCACCGACCGC TTCCTGCTGTCGGCCGCCGAGGTCTTCGTGCGCGGTGTGGACGTGGACTGGGCGGGGCTG TTCGAGGGGACCGGTGCGTCCCGGATCGACCTGCCCACCTACGCCTTCCAACACGAACAC CTGTGGGCCGTCCCGCCCGCCCCGGAGGCCGTCGCCGCCGCCGACCCGGACGACGCGGCC TTCTGGACCGCGGTCGAGGACGGTGACGTCTCCGCGCTGACCGCCGCGCTCGGCACCGAC GAGGACTCCGTCGCCGCCGTGCTGCCCGCCCTGACCTCCTGGCGCCGGGCCCGCCGCGAC CGCTCCACCGTGGACGCCTGGCGCTACCGCGTCGCCTGGAAACCCCTCGGCGGCACCCTG CCGCACCCGTCCCTGACCGGCACCTGGCTGCTGGTCACCGCCGACGGCATCGACGACACC GATGTGGCAGGGGCGTTGGAGACCTACGGCGCCGAGGTGCGCCGGCTGGTCCTGGACGAG GAGTGCGTCGACCGCGCCGTCCTGCGGGAGCGGCTGGCCGGCGCGGAGGACGTGACCGGC ATCGTCTCCGTCCTCGCCGCCGCCGAGCGGACCGACGCGGTACCGGGCACCTCCCTGGTG CTCGGCACCGCCCTGACCGTGGCACTGATCCAGGCCCTCGGCGACGCCGAAATCGACGCT CCCGTATGGGCGTTGACCCGCGGCGCGGTCTCCACCGGCCGGGCCGACGAGCTGACCGCG CCCGTCCAGGCACAGGTCACCGGCATCGGCTGGACCGCGGCGCTGGAGCACCCGCAGCGC TGGGGCGGCACCCTCGACCTGCCCGCCGCCCTCGACGCCCGGGCCGCCCAGCGGCTCGCC GCCGTGCTGTCCGGCGCCCTCGGCAGCGACGACCAGCTGGCCATCCGGCCCTCCGGGGTC TTCACCCGCCGCATCGTGCGGGCCGAGGCCACCGCCGGGCGGCCCGCCGGCACCTGGACG CCGCGCGGCACCACACTGGTCACCGGCGGCTCCGGCACCCTCGCCCCGCACCTCGCCCGC TGGCTGGCCCAACGCGGCGCCGAGCACCTGGTCCTGATCAGCCGGCGCGGCACGGCCGCC CCGGGCGCCGCCGAACTCGTCGCGGAACTGGCCGAGTCGGGCACCGAGGCGACCGTCGCC GCCTGCGACATCACCGACCGCGACGCGGTCGCCGCGCTGCTGGCCGACCTCAAGGCCGAC GGGCGCACCGTCCGCACCGTCGTGCACACCGCCGCCACCATCGAGCTGCACACCCTGGAC GCCACCACCCTGGCGGACTTCGACCGGGTGCTGCACGCCAAGGTCACCGGCGCCCAGGTC CTCGCCGAACTGCTCGACGACGAAGAGCTGGACGACTTCGTCCTGTACTCCTCCACCGCC GGCATGTGGGGCAGCGGCGCCCACGCCGCCTACGTCGCCGGCAACGCCTACCTCGCCGCG CTCGCCGAGCACCGCCGGGCCAACGGACTGCCCGCCCTGTCGCTGTCCTGGGGCATCTGG GCCGACGACCTCAAACTGGGCCGGGTCGATCCCCAGATGATCCGGCGCAGCGGCCTGGAG TTCATGGACCCGCAGCTGGCCCTGAGCGGCCTGCAGCGGGCGCTGGACGACAACGAGAAC GTGCTCGCGGTCGCCGACGTGGACTGGGAGACCTACCACCCCGTCTACACCTCCGGCCGA CCCACCCCGCTCTTCGACGAGGTGCCGGAGGTCCGCCGGCTCACCGCGGCCGCCGAGCAG AGCGCCGGGACCGTCGCCGAGGGCGAGTTCGCCGCCGCGCTGCGCGCCCTGTCCGACGCC GAGCAGCAGCGCACCCTGCTGGAGACCGTCCGCACCGAGGCGGCGTCCGTCCTCGGGCTG TCCTCCGCCGAGGACCTCACCGACCAGCGGGCCTTCCGCGACGTCGGCTTCGACTCGCTG ACCGCCGTCGGCCTGCGCAACCGGCTCGCCTCCGTCACCGGCCTGACGCTGCCCTCGACG ATGGTCTTCGACTACCCCAACCCGGCCGCGCTCGCCGCCTATCTGCACGGCGAGCTGGCC GGCGCCCGGTCCGCCGCCGCCGGCGCCGCCGCCGTCCCGACCGGCGCCCCCGACGCCGAC GACCCGATCGCGATCGTCGGCATGAGCTGCCGCTACCCCGGCGGGGTCGGCTCCGCCGAG GACCTGTGGCGGATCGCCCTGGACGAGGTCGACGCGATCTCCGGCTTCCCCGCCGACCGC GGCTGGGACGCCGAGGGCCTCTACGACCCGGACCCCGACCGGCCCGGCCGCACCTACTCC GTCCAGGGCGGATTCCTGCGCGACGTCGCCGAGTTCGACCCGGGCTTCTTCGGGATCTCG CCGCGCGAGGCGCTGTCGATGGACCCGCAGCAGCGGCTCCTGCTGGAGACCGCCTGGGAG GCGTTCGAGCACGCCGGCATCGACCCGGTCGGCCAGCGCGGCAGCCGCACCGGCACCTTC GTCGGCGCCAGCTACCAGGACTACGCCTCCGGCGTGCCCAACAGCGAGGGCTCCGAAGGC CACATGATCACCGGCACGCTCTCCAGTGTGCTGTCCGGCCGGGTGTCCTACCTCTTCGGC TTCGAGGGCCCCGCCGTCACGCTCGACACCGCCTGCTCCTCCTCCCTGGTCGCCATGCAC CTGGCCTGCCAGTCCCTGCGCAACGGGGAGAGCTCGCTGGCCCTGGCCGGCGGCGTCAGC ATCATGTCCACCCCGATGTCGTTCGTCGGCTTCAGCCGGCAGCGCGCCCTCGCCGAGGAC GGCCGCTGCAAGGCGTACGCGGACGGCGCCGACGGGATGACCCTCGCCGAGGGCGTCGGC CTGGTGCTGCTGGAGCGGCTGTCCGACGCCCGCGCCAACGGGCACCAGGTGCTCGCCGTG ATCCGCGGCTCCGCCGTCAACCAGGACGGCGCCTCCAACGGCCTGACCGCACCCAACGGC CCGTCCCAGCAGCGCGTCATCCGCCAGGCGCTGGCCAACTCCGCGGTGGCGCCCGGCGAC ATCGACGTCCTGGAGGGCCACGGCACCGGTACCGCCCTCGGCGACCCCATCGAGGCGCAG GCCCTGCTCGCCACCTACGGCCAGGACCGCGCCCCCGAACGGCCGCTGCTGCTCGGCTCG GTGAAGTCCAACATCGGCCACACCCAGATGGCATCCGGCGTCGCCAGCGTCATCAAGCTC GTCCGCGCCCTCCAGGAAGGCGTGGTGCCCAAGTCCCTGCACATCGACCGGCCCTCCACC CACGTCGACTGGTCCTCGGGCGCCATCGGGCTGCTCACCGAACGCACCCCGTGGCCCGAG ACCGGCCGGCCGCGCCGCGCCGCCGTCTCCTCCTTCGGCATCAGCGGCACCAACGTCCAC ACCATCCTCGAACAGGCCCCCGCGGACGAGGCGCCCACGCCCGCCGACCCGCCGCGGGAC GGCCTGGTGCCGGTCCTGCTCTCCGGCCGCGGCGAGGCCGCGCTGCGCGCCCAGGCCGCC CGCCTGCTCGCCTTCGTCGAGGAGCGGCCCGAGGCCCACCTCACCGACCTCGCCCACTCC CTCGCCACCTCGCGCGCCGCGCTGGAACGCCGCGCCGCCGTCATCGCCGCCGACCGCGAC ACCCTGACCCGCGGCCTGCGCGCCCTGTCCGACGGCCGGCCCGACCCCGGCCTGGTCCAG GGCACCGCGGGACGCGGCCGGACCGCCTTCCTGTTCACCGGACAGGGCAGCCAGCGCCCC GGCATGGGCCGCGAACTCCACGACCGCTACCCGGTGTTCGCCGACGCGCTGGACGAGGTG CTGGCCCGGCTCGACGACGGACCGGACCGGCCGCTGCGCGAGGTGCTGTTCGCCGCGCCC GACTCCGCCGAGGCCGCGCTCCTGGACCGGACCGGCTACGCCCAGCCCGCGCTGTTCGCC GTCGAGGTCGCGCTGTTCCGCCTGCTGACGTCCTGGGGCCTGACCCCGGACTACCTGGCC GGCCACTCCGTCGGCGAACTCGCCGCCGCGCACGTCGCCGGCGTGCTGTCGCTGGACGAC GCCTGCACTCTGGTCGCCGCCCGCGGCCGGCTCATGCAGGCGCTGCCCGAGGGCGGCGCG ATGGTCGCCCTGGAGGCCGCGGAGGACGAGGTCCTGCCGCTCCTGGAGGGGCTCACCGAC CGGGTGTCCGTCGCCGCCGTCAACGGGCCGCGGTCCGTGGTCGTCGCCGGCGTCGAGGAG GACGTGCTCCTCCTCGCCGACCTCTTCGCCGCCGACGGGCGCCGGACCAAGCGGCTGCGG GTGAGCCATGCCTTCCACTCGCCGCTGATGGACGCCATGCTCGACGACTTCGCCGCCGTC GCCCGCGGGCTGACCTACCACCCGCCGACGATCCCGTTCGTGTCGAACGTCAGCGGCGGC CTGGCCACCGCCGAACAGGTCCGCACGCCCGACTACTGGGTCGGGCACGTCCGCGCCGCG GTCCGCTTCGCCGACGGCATCGACTGGCTCGCCACCCAGGGCGACGTCCACACCTTCCTG GAGCTCGGCCCGGACGGCGTGCTCAGCGCCATGGCCCGGGAGAGCCTCACCGACCCGTCC CGCACGGCACTGCTGCCGACCCTGCGCGGCGACCGGCCCGAGGAACCTGCCCTGGTCACC GCGGTCGCCGCGGCCCACGCGCACGGCGCCCGCGTCGACTGGAGCGGGTACTTCGCCGAC CACGGCGCGCGCCGGACCACGCTGCCGACCTACGCGTTCCAACGCGAGCGGTACTGGCCC GACACCACCGCCGCCACGAGCGCCCACACGCCCGGATCCGCCCTCGACGCCGAGTTCTGG GCCGCCGTCGAGCGGGACGACGTCGCCGCCCTCGCCGCCTCCCTGGACCTGGACGACGCC ACCGTCACCGCGATGGTCCCCGCGCTCACCGCCTGGCGCCGGCGCCGCGGCGAGCAGACC GAACTGGACTCCTGGCGCTACCGCGTCACCTGGAAGCCGCGCGGCGGCGCCACCGCACCC GCCGCCCTCACCGGCCGCTGGCTCGTGCTCGTCCCGCACGACCACCAGGACCGTCAGGAC GACGCGACCGCGGCCTGGGCAGCCGACGTCGAGACCGCCCTGGGCACCACCACCGTCCGG CTGACGGTCACCACCACCGACCGCGCCGCGCTGGCCGCCCGGATCACCGAAGCCGCCGGC GACCAGGGCCCGTTCAGCGGTGTGCTGTCCCTGCTGCCGCTCGCCACCGGCGACGCCGGC CACCCCGGTGCGCCCGCCGCCCTCACCCTCACCACCACCGCCGTCCAGGCCCTCGGCGAC GCCGGCATCGACGCGCCGCTGTGGAACGTCACCCGCGGGGCCGTGGCCGTCGGCCGCGCC GAACAGGTCACCGCGCCCGAACAGGCCGCCGTCTGGGGCCTGGGCCGCGCCGTCGCCCTG GAACTGCCGGCCCGGTTCGGCGGCACCCTCGACCTGCCCGCCACCCTGGACGGCCAGGCC GCCCGCCGGTTGCGCGCGGTGCTCGCGGCTACCGACGGCGAGGACGCGGTGGCCCTGCGG CCCTCCGGCGTCTTCCTCCGCCGCCTGGCCCACGCCCCGGCCGGCCCCGACACCGCCCGC ACCGCCTTCGACCCGGCGGCCGGCACCGTCCTGATCACCGGCGGCACCGGCGGCATCGGC GGCCACGTCGCCCGCCGCCTGGCCCGCGACGGCGCCACCCACCTGCTGCTCACCAGCCGC CGCGGCCCGGCCGCCCCCGGCGCCGACGCGCTCCGCGCCGAACTGGAGGAACTGGGCGCC CGGGTCACCCTCGCCGCCTGCGACGCCGCCGACCGCGACGCGCTGGCCGCGCTCCTCGCC GAACTGCCCGACGACGCCCCGCTGTGCGCGGTGTTCCACACCGCCGGCGTCGTCGAGGAC CACGTCGTGGACGCGCTCACACCGGAGAACTTCGCCGCGGTGCTGCGCGCCAAGACCGTC GCCGCCCACCACCTGCACGAGCTGACCGCCGACCTGGACCTCGCCGCTTTCGTGCTGTTC TCCTCCACGGCCGGCGTCCTCGGCGCCGCCGGACAGGGCAACTACGCCGCGGCCAACGCC CACCTGGACGCCCTCGCCGAACACCGCCGCTCCCACGGCCTGACCGCGCTGTCCGTCGCC TGGGGCCCGTGGGCCGGCTCCGGCATGGTCGCCGACGCCGCCGAACTCACCGACCGGGTA CGGCGCGGCGGCTTCGAACCGCTCGCCCCCGAACCGGCCGTGCGCGCCCTGCTGCGCGCC ATCGAGAACGACGACACCACCGTCGCGCTCGCCGACATCGACTGGGAGCGCTTCCAGCGC GCCTTCGCCGCGGTCCGCCCGCTGCCGTTCGTCGCCGACCTCCCCGAGACCGGCCGGGCC ACCCCCGCGACCGCCACCGGCGCCGCCACCGGCCTGCGGCAGCAACTCGCCGAACTGCCG GAGCACGAGCGCCCGGCAGCGGTCCTGGACCTGCTGCGTACCCAGGTCGCCGCCGTCCTC GGCCACGCCGACCCGCGCACCGTCGAGGACGACCACGCCTTCCGCGACCTGGGCTTCGAC TCGCTGACCATCCTGGAACTGCGCAACGCCCTCAACGCCGCCACCGGCCTGAGCCTGCCC GCCACCCTGGTCTACGACCTGCCCACCCCGCGCGAGATGGCGGACTTCCTGCTCGCCGAA CTCCTCGGCACCCTGCCCACCGACACCGCCGCGACCGTCGCCAGCACGGCCTCCCCCAAG CTCTCAGCTTCGTTCGAGCAGGGCGGTACCCCCTTCGACGACCCGATCGCCGTCATCGGC ATCGGCTGCCGCTTCCCCGGCGGCGTCACCACCCCGGAGGAGCTCTGGCAGCTCCTCGAC GAGGGCCGCGACGGCATCAGCCGCTTCCCCGACGACCGCGGCTGGGACCTCGCCGCGCTG GGCGCCGGCGCCTCCGACACCCTGGAGGGCGGCTTCCTGACCGGCGTCGCCGACTTCGAC GCCCGGTTCTTCGGCATCTCGCCCCGCGAGGCGCTGGCCATGGACCCCCAGCAGCGGCTG CTGCTGGAGACCACCTGGGAGGCGCTGGAGCGGGCCGGCATCGACCCGACCACGCTGCGC GGCTCCACCACCGGCGTCTTCGTCGGCACCAACGGCCAGGACTACCCGACGCTGTTGCGC CGCTCCGCCTCGGACGTGGCCGGCTACGTCGCCACCGGCAACACCGCCAGCGTGATGTCC GGCCGCCTGTCCTACGCGCTCGGCCTCGAAGGCCCGGCCGTCACCATCGACACCGCCTGC TCCTCCTCGCTCGTCGCCCTGCACTGGGCCGGCCGGGCGCTGCGCGCCGGCGAGTGCGAC CTCGTGGTGGCCGGCGGCGTCTCGGTCATGGCCAGCCCGGACTCCTTCGTCGAGTTCTCC ACCCAGGGCGGCCTGGCACCCGACGGGCGCTGCAAGGCGTTCTCCGACGCCGCCGACGGC ACCGCCTGGTCCGAAGGCGTCGGCATCCTCGTCCTGGAACGCCTCTCCGCCGCCCGCCGC AACGGCCACCAGGTCCTCGGCCTGATCCGCGGCACCGCCGTCAACCAGGACGGCGCGTCC AACGGCCTGACCGCGCCCAACGGCCTCTCCCAGCAGCGCGTCATCGCCCAGGCACTCGCC GACGCCCGCCTGCGCCCCGCCGACATCGACGCGATCGAGGCGCACGGCACCGGCACCACC CTCGGCGACCCGATCGAGGCCCGCGCCCTGATCACCGCCTACGGCCGGGACCGGGACGCC GAACGGCCGCTGCTGCTGGGCACCGTCAAGTCCAACATCGGGCACACCCAGGCCGCCGCC GGTGCCGCCGGCGTCATCAAGATGCTGATGGCGATGCGCCACGGCACCCTGCCCAGGACG CTGCACGTGGGCACCCCGTCCAGCCACGTCGACTGGAGCGGCGGCACCGTCGCGCTCCTC GACGACGCGCGGCCCTGGCCACGGACCGGGCAGCCGCGGCGCGCCGGCGTCTCCGCCTTC GGCGTCAGCGGCACCAACGCCCACGTCGTCGTCGAGCAGGCCCCGGAAACCGAAGCCCCC GCCGCCCCGGCCGCCGAGCCGGCGCCGGAGGCCACGCCCACCGTCGTCCCCTGGGTCGTC TCCGGACGCAGCCGGGAAGCGCTCCAGGCGCAGCTGGACCGGCTCACCGCGCACACCGCC GCCCACCCCGCGCGCTCGGCGGCGGACGTCGGCCGCTCGCTGGCCACCGACCGCACGCTC TTCCCGCACCGCGCCGTGCTGCTCGCCGGCCCGGACGGGGTGCGCGAGGCCGCCCGCGCC GCCGCGCCCCGCACCCCCGGCCGCACCGCGTTCCTGTTCTCCGGACAGGGCGCCCAGCAC GCCCTGATGGGCCACGACCTGTACCAGCGCTTCCCGGTCTACGCCGACGCACTGGACACC GTCCTCGCCCAGTTCGACACCGTGCTGGACGTCCCGCTGCGCGCCGCGCTGTTCGCCGCG CCGGGCACCCCCGAGGCCGCGCTCCTGGACCAGACCGGCTTCACCCAGCCCGCGCTGTTC GCCGTCGAGGTCGCACTGTTCCGGCTCGCCGAGTCCTGGCGGCTGACGCCGGACTTCGTC GCCGGCCACTCCATCGGCGAGATCGCCGCCGCGCACGTCGCCGGGGTGTTCTCCCTGGAG GACGCCTGCACGCTGGTCGCCGCCCGCGCCTCCCTCATGCAGCAACTGCCGCGGGACGGT GCGATGGTGGCCCTGGAAGCCACCGAGGACGAGGTCGCGCCGCTGCTCACCGACGGCGTC GCACTCGCCGCGGTCAACGGCCCCCGCTCGGTGGTCGTCGCGGGCGCCGAGGACGCCGTC CGCGCGGTCGCCGACCGGCTCGCCGCCGACGGCCGCCGCACCCGCCGGCTGACGGTCAGC CACGCCTTCCACTCGCCGCTGATGGACCCGATGCTCACCGACTTCGCCCGGGTCGCGGAG GGCCTGACCTACCACGAGCCGCGCATCCCCCTCGTCTCCACCCTCCTCGGCGCCCCGGCC GGCGCCGAACTGCGCACCCCCGACTACTGGGTGCGGCACGTCCGCGAGACCGTGCGGTTC GCCGACGGCGTGCGCGCCCTGCACGACGCCGGCGCCGGCACCTTCGTGGAGATCGGCCCG GACGGCGTGCTCACCGCCCTGACCCAGCAGACCCTCGACACCGTCGAGGCCGGCGCGCCC GCCGTCGTCGTGCCGCTCCAGCGCCGCGACCGCGCCGGCGACCTCGCCCTCCTGGAGGGC CTGGCCACCCTGCACACCCACGGCACCGGCCCGTCCTGGCCCGCCTACTTCGAGGCCACC GGCGGCCACCGGACCGATCTGCCCACCTACGCCTTCCAGCGGGAGCGGTACTGGCCCGAA CTCGGCGCACCCGTCGCCACCGCCCCGCAGGACCCGGCGGCCTGGCGCTACCACGAGACC TGGGCCCCGCTGCCGGCACCCGAGGCGGCCGCGCCGGCCGGCCGCGCCCTGGTCCTCGTC CCGGCCGGGAACCGCGACACCGCGTGGATGACGGCCGTCGCCGACGCGCTCGGCGCCGAC ACCGTCACGGCCGAACCCGACGCCCTGGCCGAGCAGTTGACGGCCGCCGGCGACACACCC TGGCGCGTCGTGGTGTCGCTGCTCGCCGCCGCGTCCGAGGGGCTGCCCGCGGACGGCGCC TGGCCCGCCGCCCTCCTCGCCACCCTGGACGAGGCCGGCGTGCACGCGCCCCTGTGGTGC GTCACCCGCGGCGCCGTCGCGGTCGCGGGGGAGGCCCCGACCGCCGTCGGCCAGGCCGCC CTGTGGGGCCTGGGCCGGGTCGCCGCGCTGGACCACCCGGACCGCTTCGGCGGCCTGGCC GACCTGCCCGCCGACACCGACGCGCACGCCGCCGGGCTGCTCGCCGCGCACCTGGCCGCG CCGGGCACCGAGGCCGAGATCGCGGTCCGCGCCACCGGCGTCCACGCCCGTCGCCTGGTC CGTACGCCGGCCGCCGCCGACGGTGCCACCTGGCTGCCGACCGGCACCGTCCTGGTTGTC GGCGGCACCGGCGGCACCGGCACCATGGGCGGCCGGGCCGCCCGCTGGCTGGTCCGCGAG GGCGCCCGCCACCTCGTCCTGACCGCCCCCGACGGCACCACGACCGCCGCGGACACCGAG GCCCTGACGGCCGAACTGGCCGCGCTCGGCGCCCGGATCACCGTCGTGGACCACGACCCC ACCGCCCCGGACGGCTTCGCCGCGCTCCTCGACGGACTGCCCGACGACACCCCGCTCACC GCGGTCGTGTACGCGCCGGAGGCCGACGCCGCCCCCGGCACCGCGGCCGAGCTGTCCGCC GCACTCGCCCCCGTCACCGCCCTAGGCGCCGCCCTCACCGGCCGGCCGCTGGACGCCTTC GTCCTCTTCGGCTCCATCGCCGGGCTCTGGGGCGTGCGCGGCCGGGCCGCCGAGGCCGCG TCCGGCGCCTACCTCGACGCCTTCGCCCGCGCCTGCCGCGACCGCGGCACCCCGGCACTG GCCGTCGCCTGGGGCGCCTGGGCCGACCTGGTCGGCCCGTCCCTCGCCGCGCACCTGCGG ATGAACGGCCTGCCGGTGATGGACGCGGACACCGCACTGACCGCCCTCAGCCGGGCCGTC GCCGACGGGTCCGCCGCCGAGGCGGTCGCCGACGTCCGCTGGGAGACCTTCGCGCCCCTC CACCACGAGGCCCGCCGCACCGCCCTGTTCGACGCCCTGCCCGAGGCCCGCGGCGCGCTC GCGGAGGCCGCCCGGGACCGCGCCGACCGGAAGACCGCCGCCGGCGACTACGGCCGGTGG CTCGCCGAGCAGCCCGCCGCGGACCACGACGCCATCCTGCTGGCACTGGTCACCGAGAAG GCCGCGACCGTCCTCGGCCACGCCGACCACGACCTGCTCGAACCCGACCTGCCCTTCCGC GACCTGGGCTTCGACTCGCTGACCGCGGTCGACCTGCGCAACCAGCTCACCGCGGAAACC GGCCTCACCCTGCCCGCCACCCTCGTCTTCGACCACCCCAACCCGGCCGCCCTCGCCGCC CACCTGCGCGCCCAACTCCTCGGCGAGGCGAGCGACTCCGCCGCACCGGTGGCCGCCCCC GTCGCCCTCGGTGCCGACGACGACGCGATCGTCATCGTCGGCATGGCCTGCCGCTACCCC GGCGGGGTCACCTCGCCCGAGGACCTGTGGCAGCTGGTCGGCGACGAGGTCGACGCGGTC GGCGACTTCCCGACCGACCGCGGCTGGGACCTGGCCGCGCTCGCCGGCGACGGACCGGGC CGCAGTGCCACCGCCCAGGGCGGATTCCTCTACGACGCCACCGACTTCGACCCCGGCCTG TTCGGCATCTCGCCGCGCGAGGCCCTGGTGATGGACCCGCAGCAGCGGATCCTGCTCGAA ACGTCCTGGGAGGCCCTGGAGCGGGCCGGCATCGACCCGGCGACGCTGCGCGGCAGCGGC ACCACCGGCGTCTTCGTCGGCGGCGGCTCCGGCGACTACCGGCCGCCGGAGGAGGCCGGG CAGTGGCAGACCGCCCAGTCCGCCAGCCTGCTCTCCGGTCGCCTCGCCTACACCTTCGGC ATCCAGGGCCCCACCGTGTCGGTCGACACCGCCTGCTCCTCGTCGCTGGTCGCGCTGCAC CTGGCCGCGCAGGCCCTGCGCGCCGGCGAATGCTCGATCGCGCTGGCCGGCGGCGTCACC GTGATGGCCACCCCGGTGGGCTTCGTCGAGTTCAGCGCCCAGGGCGCCCTGTCGCCGGAC GGCCGCTGCCGCGCCTTCTCCGACGACGCCAACGGCACCGGCTGGTCCGAAGGCGTGGGC ATGCTCGTCGTCGAACGGCTCTCCGACGCCCGCCGCAACGGCCACCGCGTCCTCGCCGTG CTCCGCGGCTCCGCCATCAACCAGGACGGCGCGTCCAACGGCCTGACCGCCCCCAGCGGC CCCGCCCAGCAGCGCGTCATCCGCCAGGCCCTCGCCAACGCCCGACTGCGCCCCGCCGAC ATCGACGCCGTCGAGGCCCACGGCACCGGCACCAGGCTCGGCGACCCCATCGAGGCCCAG GCCCTGCTCGCCACCTACGGCCAGGACCGCGAGCGGCCCGTGCTGCTCGGCTCGCTCAAG TCCAACATCGGCCACACCCAGGCCGCCTCCGGCGTCGGCGGCGTCATCAAGATGGTCCTC GCCATGCAGCACGGCGAACTGCCGCGCTCCCTGTACGCCGAGAACCCCTCGTCGCACGTG GACTGGACCGCCGGCCGCGCCCACCTGCTCACCGCCAGGACCCCGTGGCCCGACTCCGGT CGGCCGCGCCGCGCCGCCGTCTCCTCCTTCGGCGCCAGCGGCACCAACGCCCACGCCATC CTGGAGCAGCCGCCGCGCGAGGAACTCCCCGCGCGCCCCGCGGACGACGGCGCCCCGCTG CCGTTCTTGCTCTCCGGCCGCTCGCAGAACGCCCTGCGCGCCCAGGCCCGCCGACTCCTG GCCCGCCTCACCGCCCACCCCGACACCCGGGCCGCCGACCTGGCGTACTCCCTGGCGACC ACCCGGGCCGCCTTCGAGCACCGGGCCGCGATCACCGCCACCGACCACGACGGCCTCCGC ACCGGCCTGACCGCCGTCGCCGAGGGCACCACCGCCCCGCACACCGCCGAACACCACCTC CAGGGCACCGGAAAGCGCGCCGTGCTCTTCTCCGGCCAGGGCTCCCAGCGCCTGGGCATG GGCCGCGAACTGCACGAGCGCCACCCGGTGTTCGCCGAGGCGTTCGACTCCGTACTGGCC CGCCTCGACGACCGGCTCGACACCCCCCTGCGGGACGTCGTCTGGGGCACCGACGAGGAG GCGCTGCACGCCACCGGGAACACCCAGCCCGCCCTGTTCGCCGTCGAAGTCGCGCTCTAC CGCCTGATCGAATCCTGGGGCGTGCGGCCCGACTTCGTGGCCGGCCACTCCGTCGGCGAG CTCGCCGCGGCCCACGTCGCCGGGGTGCTCTCCCTGGACGACGCCTGCCGCCTGGTCGCC GCCCGCGCCGCCCTCATGCAGCGCCTCCCGGCCGGCGGCGCCATGATCGCCGTCGAGGCC ACCGAGGACGAGGTCACCCCGCTCCTCACCGACGGCGTGTCCCTCGCCGCGGTCAACGGA CCGACCGCCGTGGTCCTCTCCGGCGCGGGCGACGCCGTGACCGCCCTGGGCCAGGCGCTG GCCGAACGGGGCCACCGCACCACCCGGCTGCGGGTCAGCCACGCCTTCCACTCGCACCTC ATGGACCCGATGCTGGCGGACTTCCGCACCGTCGCCGAGGGCCTGGAATACCACCCGCCG CGCATCCCCGTGGTCTCCAACCTCACCGGGGACGTCGCCGACGCGGCCGACCTGTGCTCC GCCGACTACTGGGTGCGCCACGTCCGCGGCACCGTACGGTTCGCCGACGGCGTGCGCACC ATGGCCGACCGCGGCGTGCACCTCTTCCTCGAACTCGGCCCGGACGCCGTGCTGTCGGCC ATGGCCCGCCAGTGCGCACCGGACGCCGTCGTCGTCCCGGCCCTGCGCCGCAACCGCGAC GAGGACGAGACGCTGGTCGGCGCCGTCGCGCGACTGCACGTCCACGGCGCGGGTCCGCGC TGGGACGCGTACTTCGCCGGCCGCGGCGCCCAGTGGCTGGACCTTCCGACGTACCCCTTC CAGCGCGGCCGCTTCTGGCCGGAGTCCCTTCCGGGCGCCGCATCGGCCGCCCCGGCAGCC GGACAGCCGGCCGAGACCGACGCGGCCTTCTGGGACGCCGTCGCACAGGAGGACTTCACC GCATTGGAATCCGTACTCGACGTCGAGAGCGACGCACTGTCCAAGGTGCTGCCGGCCCTG ATGGACTGGCGCAGCCGCCAGGCCGACGAGTCCCAACTGGCAGGCTGGCGCCACCGCATC GTCTGGAAGCGGCTCACCGGCGCCGCCCTGGCACACCGCAAGGCGCTCAGCGGCACCTGG CTCGCGGTGGTCCCCGAGGGCTTCGCCGACGACCCCTGGGTGACCACCACCCTGGACGGC CTCGGTACCCACCTCGTGCATCTGGAGGTCGCGGAGGCCGACCGGGCCGCGCTGGCCGAC GCGATCGCGGCCCGCACCGCCGACGGCACCCGCTTCGGCGGCGTAATCTCCCTGCTGGCC CTGCGCGAGGAGCTCACCGGCGCGGTGCCCGAGGGGACCGCCCTGACCACCACCCTCCTC CAGGCCCTCGGCGACGCCGGCGTCGACGCACCGCTGTGGTGCGTCACCCGCAGCGCCGTC TCCGCCGGCCGCACCGACCGGCCGCACCGACCGCTCCAAGGCGCCGTCTGGGGCCTGGGC CGGGTCGCGGCCCTTGAGTACCCGCAGCGCTGGGGCGGCCTGGTGGACCTGCCGGAGGAG CCCGACGAGCGGTCCGCGGCCGGCCTCGCCGCCGTCCTGGCCGGTCTGGACGGCGAGGAC CAGGTCGCCGTGCGCGGCACCGCGGTGCTCGCCCGCCGCCTGGTGCCGGCTCCCGGCCGC AAGCCGTCCCGGCCCTGGCACCCGTCCGGCACCGTCCTGGTCACCGGCGGCACCGGCGCC CTCGGCGCGCACGTCGCCCGCCGCCTGGCCAAGGACGGCGCCCAGCACCTCGTCCTGCTC AGCCGCCGCGGCCCGGACGCTCCCGGTGCGGCGGAACTGCGCGCGGAACTGGACGCGTTG GGCACCGACGTCACGGTCGCCGCCTGCGACGTCGCCGACCGCGACCAGCTGACGGCCGTC CTGGACGCGCTGCCCGCCGACCGGCCGCTGACCGGTGTGGTGCACACCGCCGGCGTCCTC GACGACGGCGTACTGGACCGGCTCACCCCCGAGCGGTTCCAGGAGGTGTTCCGCGCCAAG GTCACCTCGGCCCTGCTGCTGGACGAGCTGACCCGCGACCGCGAGCTGGCCGCGTTCGTC CTCTTCTCCTCCGCCTCCGCCGCGGTCGGCAACCCGGGCCAGGCCAACTACGCCGCTGCC AACGCCGTCCTGGACGCGCTCGCCGAACAGCGCCGGGTGCTCGGCCTGCCCGCCACCTCG GTCTCCTGGGGTGCCTGGGGAGGCGGCGGCATGGCCGACGCCGACGGCGCGGACGAGGCC GCCCGGCGCGCCGGCGTCGGCGCCATGGACCCGCACCTCGCCGTGGAAGCCCTGCTGCGC CTGGTCGCCGAGAAGGAGCCGACCGCGGTGGTCGCCGAGGTGGCCCTGGACCGGTTCGCC GGCGCCTTCGGCGGCAGCCGACCCAGCGCCCTGCTGCGGGAGTTCCCCGGCTACCGCGAG GCGCTCGCCGCCCAGGCGGAGCAGGCCGCGGACGGCGGCGGGCTGGCCGCCCGACTGGCC GCGCTGCCGCCCGCCCGCCGCCTGGACACCGTTGTGGACCTGGTGCGCACCCGCGCCGCG CAGGTGCTCGGCTACCCCGACACCGAAGCGGTCGCCGCCGAACGGTCCTTCCGCGACCTG GGTGTCGACTCGCTCGGCGCCGTCGAGCTGCGCAACCAACTGAGCGCGGCCACCGGCCTG AACCTGCCGGCGACGCTGGTGTTCGACCACCCGACCCCCCTGGTCCTGGGGGAGCACATC CTCGGCGGGCTCTTCCCGGACGAGCCCGCCGGGTCCGACGACGAGACGGAGATCCGGGCC CTGCTGGCCTCCGTCCCGCTCGACCAACTGCGGGAGATCGGGGTCCTGGAGCCCCTGCTC CAGCTCGCCGGACGCGGCGGCCGGGCCGCGGACGGCGACGACGGCGAGTCCGTCGACTCG ATGACAGTGGCAGACCTGGTGCGGGCCGCGCTCAACGGCCAGTCCGACCTGTAG
Feature
| BLASTP Database:UniProtKB:2011_09 |
|
|---|---|
| InterPro Database:interpro:38.0 |
IPR001227 Acyl transferase domain (Domain)
IPR006162 Phosphopantetheine attachment site (PTM)
IPR009081 Acyl carrier protein-like (Domain)
IPR013968 Polyketide synthase, KR (Domain)
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
IPR014043 Acyl transferase (Domain)
IPR015083 Polyketide synthase, docking (Domain)
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
IPR016038 Thiolase-like, subgroup (Domain)
IPR016039 Thiolase-like (Domain)
IPR016040 NAD(P)-binding domain (Domain)
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
IPR020806 Polyketide synthase, phosphopantetheine-binding domain (Domain)
IPR020807 Polyketide synthase, dehydratase domain (Domain)
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain (Domain)
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
|
| SignalP | No significant hit |
| TMHMM | No significant hit |
![[559-691] G3DSA:3.40.366.10](../../img/X2.gif "[559-691] G3DSA:3.40.366.10"){kind=small}
![[1748-1763] PS00012](../../img/P.gif "[1748-1763] PS00012"){kind=small}
![[1724-1789] 1.2e-10 PF00550](../../img/H.gif "[1724-1789] 1.2e-10 PF00550"){kind=small}
![[1713-1829] 1.50000306971104e-28 SSF47336](../../img/B.gif "[1713-1829] 1.50000306971104e-28 SSF47336"){kind=small}
![[1720-1790] PS50075](../../img/M.gif "[1720-1790] PS50075"){kind=small}
![[571-868] 8.6000633021393e-123 SM00827](../../img/R.gif "[571-868] 8.6000633021393e-123 SM00827"){kind=small}
