Soraph_00120 Soraph_00120   last last

Soraph_00130 : CDS information

close this sectionLocation

Organism
StrainSo ce26
Entry nameSoraphen
Contig
Start / Stop / Direction65,934 / 66,941 / + [in whole cluster]
65,934 / 66,941 / + [in contig]
Location65934..66941 [in whole cluster]
65934..66941 [in contig]
TypeCDS
Length1,008 bp (335 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category5.4 hypothetical protein
Producthypothetical protein
Product (GenBank)xylanse-arabinofuranosidase bifunctional enzyme
Gene
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)
  • Orf7
Reference
ACC
PmId
[12039053] Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26. (Gene. , 2002)
[15289572] Heterologous production of the antifungal polyketide antibiotic soraphen A of Sorangium cellulosum So ce26 in Streptomyces lividans. (Microbiology. , 2004)
comment
[PMID: 12039053](2002)
Soraphen A biosynthetic gene clusterの報告。
Orf7(335aa): xylanse-arabinofuranosidase bifunctional enzyme

---
[PMID: 15289572](2004)
clusterの境界について検討。
C末側は配列解析(orf5はhypoで、orf6,7が一次代謝遺伝子）と、Sor. cellulosum So ce26 SJ3での遺伝子破壊でsoraphen類似体産生に影響しなかったことから、orf5-7はsor clusterでなはいと述べている。

close this sectionSequence

selected fasta
>hypothetical protein [xylanse-arabinofuranosidase bifunctional enzyme]
MTVGEFPNATPSWTVSAWVRVLTDQPPAEDTLRTVISTENTGGWELNIDYAGEAPGMHFA
FWKGPEISDYHSALCFCLELQRWTHAAGVVDGEALTMSLYIDGRLYSTMPIEKTISPGPT
SLYVGRWPQEGRLLVGDVDDIAIYSRALAAAEVAELSQHAVPAEVEADISTDTTYTLVGV
QSGLCVDVDAAVITADDVVLQLWDCNGGTNQQFRFEAVDGGYYRIRNVQSDKCLDVRSAS
TADGAAIVQYTCHDNANQQWSVTEAGDGAVRITSRLSGRVIDAYGSPPASGTALVQRASS
GGTSQQFKLTPLETGTGTGGTGGTGGTGGTGGTGP
selected fasta
>hypothetical protein [xylanse-arabinofuranosidase bifunctional enzyme]
ATGACGGTCGGCGAGTTCCCGAACGCCACCCCGAGCTGGACCGTCTCGGCGTGGGTTCGT
GTGCTGACCGACCAGCCCCCCGCCGAGGACACCCTGAGGACCGTGATCAGCACCGAGAAC
ACCGGCGGATGGGAGCTCAACATCGACTACGCCGGCGAGGCGCCGGGCATGCACTTCGCG
TTCTGGAAGGGGCCCGAGATCAGCGACTACCACAGCGCTCTATGTTTCTGCCTGGAGCTC
CAGCGGTGGACACACGCCGCCGGGGTCGTCGACGGCGAGGCGCTCACCATGAGCCTCTAC
ATCGACGGGCGCCTCTACAGCACCATGCCCATCGAGAAGACGATCTCGCCCGGCCCGACC
AGCCTCTACGTCGGTCGATGGCCGCAGGAGGGTCGGCTCCTCGTCGGGGACGTCGACGAC
ATCGCGATCTACAGCCGAGCGCTCGCCGCGGCGGAGGTCGCCGAGCTCTCCCAGCACGCC
GTCCCGGCGGAGGTCGAGGCGGACATCTCGACGGACACCACCTACACCCTGGTCGGCGTC
CAGAGCGGGCTCTGCGTGGACGTCGACGCCGCCGTGATCACGGCCGACGATGTCGTCCTG
CAGCTCTGGGATTGCAACGGCGGCACCAACCAGCAGTTCCGCTTCGAGGCGGTGGACGGC
GGGTATTACCGGATCCGCAACGTCCAGAGCGACAAGTGCCTCGACGTCCGCAGCGCGTCG
ACCGCCGACGGCGCCGCCATCGTCCAGTACACCTGCCACGACAACGCCAACCAGCAATGG
TCCGTCACCGAGGCAGGCGACGGCGCCGTCCGCATCACGTCGCGCCTCAGCGGCAGGGTC
ATCGACGCTTACGGCTCCCCGCCCGCCAGCGGCACCGCCCTCGTCCAGAGGGCTTCCAGC
GGCGGCACCAGCCAGCAGTTCAAGCTGACCCCGCTCGAAACTGGCACCGGCACCGGCGGC
ACCGGCGGCACCGGCGGCACCGGCGGCACCGGCGGCACGGGCCCGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR000772 Ricin B lectin domain (Domain)
[172-312] 5.09998762524166e-37 SSF50370
SSF50370   RicinB_like
[173-307] 2.1e-22 PF00652
PF00652   Ricin_B_lectin
[172-310] 1.99999636034521e-23 SM00458
SM00458   RICIN
[171-310] PS50231
PS50231   RICIN_B_LECTIN
IPR008985 Concanavalin A-like lectin/glucanase (Domain)
[9-167] 7.49999605851445e-23 SSF49899
SSF49899   ConA_like_lec_gl
IPR013320 Concanavalin A-like lectin/glucanase, subgroup (Domain)
[6-160] 5.40000000000002e-21 G3DSA:2.60.120.200
G3DSA:2.60.120.200   ConA_like_subgrp
SignalP No significant hit
TMHMM No significant hit
Soraph_00120 Soraph_00120   last last
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