first first   Avil_00020 Avil_00020

Avil_00010 : CDS information

close this sectionLocation

Organism
StrainTü57
Entry nameAvilamycin
Contig
Start / Stop / Direction1,590 / 2,678 / + [in whole cluster]
1,590 / 2,678 / + [in contig]
Location1590..2678 [in whole cluster]
1590..2678 [in contig]
TypeCDS
Length1,089 bp (362 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category5.1 general function
Productputative GTP-binding protein
Product (GenBank)putative GTP binding protein
Gene
Gene (GenBank)aviX1
EC number
Keyword
Note
  • It is supposed that this ORF is not involved in avilamycin biosynthesis.
Note (GenBank)
  • AviX1
Reference
ACC
PmId
[11410376] Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tu57 and production of new antibiotics. (Chem Biol. , 2001)
comment
avilamycin A生合成遺伝子クラスターの報告。

AviX1: GTP-binding protein from M. tuberculosis [Proposed function:Unknown]

avi gene clusterの境界決定のための実験をしていないが、AviRb-AviZ2が生合成遺伝子だと記述している。
Related Reference
ACC
P44681
PmId
comment
Haemophilus influenzae
GTP-dependent nucleic acid-binding protein EngD_engD

YchF(現在EngD)のX線結晶構造解析を行った文献。
YchFの機能として、nucleoprotein complexの一部としてGTP-dependent translation factorとして機能するのではないかと考察している。

close this sectionSequence

selected fasta
>putative GTP-binding protein [putative GTP binding protein]
MSLTIGIVGLPNVGKSTLFNALTKNDVLAANYPFATIEPNVGVVGVPDARLTKLAEIFSS
QRILPATVDFVDIAGIVRGASEGEGLGNKFLANIRESDAICQVIRAFKDENVVHVDGKVS
PKDDIETINTELILADLQTIEKVLPRLQKDSRIKKDLAPKVKAVEEAKEILERGDTLFAH
GIVQGTERNELLHDLHLLTTKPFLYVFNVDEDELIDEDFKNEQRALVAPAEAIFLNAKLE
ADLAELDDDEALELLQSVGQDEPGLATLARVGFNTLGLQTYLTAGPKESRAWTIKKGATA
PEAAGVIHTDFQKGFIKAEVISFTDLVETGSVAEARAKGKARMEGKDYVMQDGDVVEFRF
NV
selected fasta
>putative GTP-binding protein [putative GTP binding protein]
GTGTCGCTCACGATCGGAATCGTCGGTCTGCCGAATGTCGGCAAGTCGACCCTGTTCAAC
GCCCTGACCAAGAACGACGTGCTGGCGGCCAACTACCCGTTCGCCACGATCGAGCCCAAC
GTCGGTGTCGTGGGCGTCCCCGACGCACGCCTCACCAAGTTGGCCGAGATCTTCTCCTCC
CAGCGCATCCTCCCGGCGACCGTCGACTTCGTCGACATCGCCGGCATCGTGCGCGGCGCC
TCCGAGGGGGAGGGCCTGGGCAACAAGTTCCTCGCGAACATCCGTGAGTCCGACGCGATC
TGCCAGGTCATCCGCGCCTTCAAGGACGAGAACGTCGTCCATGTCGACGGCAAGGTCTCG
CCCAAGGACGACATCGAGACGATCAACACCGAGCTGATCCTCGCGGACCTCCAGACGATC
GAGAAGGTCCTGCCCCGCCTCCAGAAGGACTCGCGGATCAAGAAGGACCTCGCGCCGAAG
GTGAAGGCCGTCGAGGAGGCCAAGGAGATCCTGGAGAGGGGCGACACCCTCTTCGCCCAC
GGCATCGTCCAGGGCACCGAGCGCAACGAGCTCCTGCACGACCTGCACCTGCTCACCACC
AAGCCCTTCCTCTACGTCTTCAACGTCGACGAGGACGAGCTGATCGACGAGGACTTCAAG
AACGAGCAGCGCGCCCTGGTCGCCCCCGCCGAGGCCATCTTCCTCAACGCCAAGCTGGAG
GCCGACCTCGCCGAGCTCGACGACGACGAGGCCCTCGAACTCCTCCAGTCCGTCGGCCAG
GACGAGCCCGGCCTCGCCACCCTCGCCCGCGTCGGCTTCAACACCCTCGGCCTGCAGACC
TACCTGACGGCCGGCCCGAAGGAATCCCGCGCCTGGACCATCAAGAAGGGCGCCACCGCC
CCCGAGGCCGCCGGCGTCATCCACACCGACTTCCAGAAGGGCTTCATCAAGGCGGAGGTC
ATCTCCTTCACCGACCTGGTGGAGACCGGCTCCGTCGCCGAGGCCCGCGCGAAGGGGAAG
GCGCGTATGGAGGGCAAGGACTATGTGATGCAGGACGGGGACGTGGTCGAGTTCCGCTTC
AACGTGTAG

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR004396 Conserved hypothetical protein CHP00092 (Family)
[1-362] TIGR00092
TIGR00092   TIGR00092
[1-362] PIRSF006641
PIRSF006641   CHP00092
IPR006073 GTP binding domain (Domain)
[5-25] 3.1999989904635e-34 PR00326 [26-44] 3.1999989904635e-34 PR00326 [70-85] 3.1999989904635e-34 PR00326 [87-105] 3.1999989904635e-34 PR00326
PR00326   GTP1OBG
[5-113] 5.69999999999998e-20 PF01926
PF01926   MMR_HSR1
IPR012675 Beta-grasp domain (Domain)
[267-362] 2.99999999999998e-48 G3DSA:3.10.20.30
G3DSA:3.10.20.30   Ferredoxin_fold
IPR012676 TGS-like (Domain)
[278-362] 4.60000044330862e-36 SSF81271
SSF81271   TGS-like
IPR013029 Domain of unknown function DUF933 (Domain)
[278-361] 4.6e-40 PF06071
PF06071   YchF-GTPase_C
IPR023192 TGS-like domain (Domain)
[119-192] 4.29999999999998e-18 G3DSA:1.10.150.300
G3DSA:1.10.150.300   G3DSA:1.10.150.300
SignalP
[1-29] 0.206 Signal
Eukaryota   
[1-29] 0.382 Signal
Bacteria, Gram-positive   
TMHMM No significant hit
first first   Avil_00020 Avil_00020
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