Herb_00060 Herb_00060   Herb_00080 Herb_00080

Herb_00070 : CDS information

close this sectionLocation

Organism
StrainAM 3672
Entry nameHerbimycin A
Contig
Start / Stop / Direction9,207 / 8,437 / - [in whole cluster]
9,207 / 8,437 / - [in contig]
Locationcomplement(8437..9207) [in whole cluster]
complement(8437..9207) [in contig]
TypeCDS
Length771 bp (256 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.3 transport
Productputative ABC transporter ATP-binding protein
Product (GenBank)unknown
Gene
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)
  • ORF7p; ORF7; similar to FtrE and Streptomyces coelicolor SC00998 permease (Fe)
Reference
ACC
PmId
[16085885] Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption. (Appl Environ Microbiol. , 2005)
comment
herbimycin生合成系gene clusterのクローニングを行い、同じbenzoquinone ansamycin系のgeldanamycin のgene clusterと比較し、一部の遺伝子欠損株を作成してその生合成における関与を調べた文献。

ORF07(771bp):permease (Fe); homolog of FtrE, S. coelicolor SC0998
機能実験、詳細記載無し。
論文のTable 4. では、8437-9240となっており、全長804bpとなっている。
Family/Domain
FD
IPR003593, IPR003439
comment
[IPR003439] ABC transporter-like (Domain)

Function
GO:0005524 ATP binding
GO:0016887 ATPase activity

close this sectionSequence

selected fasta
>putative ABC transporter ATP-binding protein [unknown]
MRIDIEDLRVAYAGRTVVADAHLIAAEGEITGLVGPNGSGKSTLLRTVYRHLKPAAGRVL
LDGSDIRELSPARSARHIAALPQERGGDFELTVREVVAMGRTPYKRAFAGEDAADRDIVA
GALADVGMGDHTDRHFSELSGGERQRVLLARAFAQQTDVLVLDEPTNHLDVRHQVELLAL
LRGRRRTTLVSLHDLNAAASVCDRLHVLHEGRVVASGTPREVLRPPLLAEVFGVRAAVVE
HPLTGDPLIAFDHREL
selected fasta
>putative ABC transporter ATP-binding protein [unknown]
TTGAGGATCGATATCGAGGACCTGCGGGTCGCGTACGCCGGACGTACGGTCGTGGCCGAT
GCCCACCTCATCGCGGCCGAAGGCGAGATCACCGGTCTGGTGGGGCCCAACGGCAGTGGC
AAGTCCACTCTTCTGCGGACCGTGTACCGGCATCTGAAGCCCGCCGCCGGACGTGTGCTG
CTCGACGGCTCCGACATCCGCGAGCTGAGCCCCGCGCGGTCGGCCCGGCACATCGCCGCG
CTCCCACAGGAGCGGGGCGGGGACTTCGAGCTGACCGTACGTGAGGTGGTCGCCATGGGC
CGCACCCCCTACAAGCGGGCGTTCGCCGGGGAGGACGCCGCCGACCGGGACATCGTCGCG
GGTGCTCTCGCGGACGTCGGCATGGGGGACCACACCGACCGCCACTTCAGCGAGCTGTCC
GGCGGCGAGCGGCAACGTGTGTTGCTGGCCCGTGCGTTCGCCCAGCAGACGGACGTCCTG
GTCCTGGACGAGCCGACGAACCACCTCGACGTACGCCACCAGGTCGAACTCCTCGCCCTG
CTGCGCGGCCGACGCCGTACGACCCTGGTGTCGCTGCATGACCTCAACGCCGCCGCCTCC
GTGTGCGACCGGCTGCATGTCCTGCACGAGGGTCGCGTGGTCGCCTCCGGTACACCCCGC
GAGGTGCTGCGACCGCCCCTGCTGGCCGAGGTGTTCGGCGTACGTGCGGCCGTGGTCGAG
CATCCGCTGACCGGGGACCCGCTGATCGCCTTCGACCACCGGGAACTATGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR003439 ABC transporter-like (Domain)
[3-235] PS50893
PS50893   ABC_TRANSPORTER_2
[42-167] 5.90000000000001e-23 PF00005
PF00005   ABC_tran
IPR003593 AAA+ ATPase domain (Domain)
[27-243] 5.20000089003336e-21 SM00382
SM00382   AAA
IPR017871 ABC transporter, conserved site (Conserved_site)
[139-153] PS00211
PS00211   ABC_TRANSPORTER_1
SignalP No significant hit
TMHMM No significant hit
Herb_00060 Herb_00060   Herb_00080 Herb_00080
Page top