Herb_00170 Herb_00170   Herb_00190 Herb_00190

Herb_00180 : CDS information

close this sectionLocation

Organism
StrainAM 3672
Entry nameHerbimycin A
Contig
Start / Stop / Direction48,197 / 58,492 / + [in whole cluster]
48,197 / 58,492 / + [in contig]
Location48197..58492 [in whole cluster]
48197..58492 [in contig]
TypeCDS
Length10,296 bp (3,431 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category1.1 PKS
Productpolyketide synthase
Product (GenBank)HbmAII
Gene
Gene (GenBank)hbmAII
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[16085885] Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption. (Appl Environ Microbiol. , 2005)
comment
herbimycin生合成系gene clusterのクローニングを行い、同じbenzoquinone ansamycin系のgeldanamycin のgene clusterと比較し、一部の遺伝子欠損株を作成してその生合成における関与を調べた文献。

HbmAII(10,296bp):PKS modules 4 and 5
Module 4 (KS-AT-DH-KR-ACP)
Module 5 (KS-AT-KR-ACP)

hbmAII自体の機能実験は無し。

close this sectionPKS/NRPS Module

4 methylmalonyl-CoA
5 methoxymalonyl-ACP
KS34..409
AT573..893
DH941..1103
KR1430..1610
ACP1716..1786
KS1809..2184
AT2347..2668
KR2971..3149
ACP3253..3323

close this sectionSequence

selected fasta
>polyketide synthase [HbmAII]
MANDEKLLNYLKRVTADLHQTRERLRKAEAATEEPIAIVGMGCRFPGGVTTPNGLWDLVA
DGRDAIAGFPEDRGWNLENLFHADPDSVGTSYVREGGFLADAAEFDAEFFGISPREALAT
DPQQRLLLETAWETLEHAGIDPSSLADSDVGVFTGLANGDYALTVDQVPEGFEGYLGLGG
AGSIASGRISYSLGLLGPAVTLDTGCSSSLVAMHLASYALRSGECSMALAGGVMVMATPG
GFVGFSRQRGLARDGRCKSFGEGADGTNWSEGAGLVLLERLSDARRHGHEVLAVIRGTAV
NQDGASNGITAPNGPSQERVIRQALANAGLTVADVDAVEAHGTGTSLGDPIEAQALLATY
GQNRPEDQPLWLGSIKSNIGHTQAAAGVAGVIKMVQAMRHGVLPKTLHADEPTTKVDWSQ
GAVSLLSEARPWPETGHPRRAGISSFGVSGTNAHVILEQAPPEVAVPEAEASETGTPGLV
ATGGVVPWMLSGKTPAALRAQAERLVSHLESGSDANPVDVGWSLATTRAALDHRAVILAT
DTEDGIATARALAEGRPDPLLVTGQTGTDGKTVFVFPGQGAQWVGMGAQLLNTSPAFATR
LRECADALAPYTDWSLIDVITGAPDAPSLDRVDVVQPATFAVVVSLATLWQSMGIHPDAV
TGHSQGEIAAACVAGHLTLTNAAKIVALRSQIIADHLAGHGGMMSVLASREQVEEALTPW
QGKLWIAAHNSPQATVVAGDIDALHELHAHYTDQDIRARIIPVDYASHTGHVDTIKNELH
QTLADTTTEPGTLPWLSTVDGEWIEPDTLDSGYWYRNLRQTVQFHTAITTLADQGYRTYI
EISPHPVLTTAIQETLEANDTSNTTITGTLRRDDDTPTRLLTNLAHLTTHGTPVNWPTLF
TGTHPTRITLPTYPFQHHHYWLPRNTSTGDIASAGLHDPAHPLLTAAVHLPDTGGTVLTG
RLSLTTHPWLADHTVSGAVLLPGAAMAELAIRAGDETATPTLDELVIEQPLALPDSGFLD
IRVVVGGPDEAGRRDVRIYSRAAEESAQWTVHATGTLAQDTTAPPSPTAAEWPPAGAEPV
AVEGLYEQMAEGGYDYGPTFQGLKAVWTRDGDVGEVFAEAALPEEQTEAAGRFGIHPALL
DAALHASNYCLPGEPGGRMLLPFAWNDIRLHATGATSVRVHARYTEDDGLSEVLVDTAGG
LVASIGSLVLREVDAAQLEALASTSVNDALWTVTWTEHTATTDEIRWGTLGDVSPVLAAA
EAPAFADVTEIATAPATEIAGTEDRPALIVADTTAWQSRDADPITRARELATRALDLLQR
WVTLPELSETRLAVLTRGAMAVHDSAEVTDSAAAAIWGLVRSAQSEHPGRIQLIDADGHS
DHTLRSALSTALTTDQPQLALRDNTLWAPRLTPTTPADTPAQPLPLNPEGTVLVTGGTGT
LGALTARHLITHHGARHLLLISRQGPDAPGATDLTTELTELGATVHITACDTADRDQLAT
TLADIPADHPLTAVIHTAGTLDDGTLTALTPNRLDTVFRPKVDAITHLHHLTHDHDLAAF
VIYSSATGTLGTPGQANYAAANTYADALVHQRHAAGLPATSLAWGLWETTSALTATMNTE
DRRRTHRGGVAALTDDEGLALLDRALTATHHPHLVPIKISPASLRADDTAQPVPPLLRHL
VRRPTRRTAHTPAPADTLSLAQRLAALDQGERLRHLTELVRTEAAAVLGHTTIDSIGPDQ
PFRDVGFDSLTAVELRNRLNAATGLRLPATVVFDYPTPAITAGYLRDELFGPAEAAPAAV
AGPGADADDPVVVVGMACRLPGRVTDPDGLWRLVADGEDGIGAFPTDRGWDLDTLFDPDP
DRVGATYVREGGFVAGATEFDADFFGISPREAVAMDPQQRLLLETAWETFEQAGIAPRSV
QGSDTGVFAGVIYHDYGTNAGELPEGSETYLSTGKSGSVVSGRVAYALGLTGPAVTVDTA
CSSSLVAIHWAAKAVREGECSMALAGGVTVMSTPDGFVSFSHQRGLAPDGRSKSFGEGAD
GTTFSEGVGLVLLERLSEARRNGHEVLAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQAL
SSAGLSATDIDAVEAHGTGTALGDPIEAQALLATYGQDRPADQPLWLGSLKSNIGHTQAA
AGIAGVIKMIQAMRHGMLPRTLHADEPTTKVDWTSGAVSLLTEARPWPETGHPRRAGISS
FGVSGTNAHLILEQAPEEAATAPETTEPEAPGLVATGGAVPWVLSAKSPTALRAQAERLI
AHLHAHPETDPVDMGWSLATSRAALEHRAVVLATDLDQATAALTALSEGQPHPSLITGET
GSDGKTVFVFPGQGAQWAGMGAQLLDTSPVFATRLHECAEALAPYTDWSLIDVITGAPDA
PSLDRVDVLQPTTFAIMVSLAALWQANGIHPDAVIGHSQGEIAAACVAGHLTLTNAAKIV
TLRSQTIAHHLTGHGAMMSVLASPTWVQETLAPWHGHLWIAAVNGPASVSVSGDPDALAE
FGTTLSKAKVYRWQLPGVDFAGHSGHVDTIKDQLHNVLDGITATPGHTAWMSTVDADWAN
PTHIDPDYWYRNLRDTVRFEEATRALLTHGHRVFIEVSTHPVLTTAIQETTETLPEVRAT
ITGTLRRDDGAADRVLAGLGGLFAAGVPVDWGALFAGTGARRVPLPTYAFQHRHYWLEPA
RTPTRAETADGSLWAAIEDGDTQSLARDLEVDAAALGTVLPALASWRRRSREDSLTDAWR
YRIGWTRVAAADPQMSGRWLVLVPAVRAGSARVRAVLDGLAARGAEVVAAEVSETGREAL
GDQVKSADGGAGVVSLLSWDDRADTEYGTVSTGTAATLAAAQALRDHGITAPLWCVTSGG
VAVAGETADPVQSAVWGFGAVLGLDHPDTFGGLIDLPAEREGDGEALPDGLFAALSSPEG
EDQLAVRADGLFARRMVRDRDGSGSLWKPRGTVLVTGGTGGLGSHVARWLATSGADHVVL
LSRQGGDAPGAAELVADLAGVQVTLAACDVTDREAVAAVLAEAERTHPLTAVVHTAGAGL
PSAPVTEVTAEEFAAVTGAKVRGALVLDQLVGDRQLDAFVLFSSGAGVWGSGGQAPYAAG
NAFLDGLAARRRAHGLAATSVAWGGWGGGLGMIDADGGDQWRRIGILPMDPAPALRAMAR
AVGSGLPNAIVADVDWARFVPGYTMARERPLLRQLPEVAEILAADARGGGASRREVLLGS
LAELTGPEQEVFLTDLVRREAAAVLGHADGDAVEPERAFKDTGFDSLTAVELRNRINAAT
GLQLSPTVVFDYPKPTTLARRLRTELVPAVNGDANGGMDGDGTADGGAVGAEGRERQIRR
VLASVPLRRFHELGVLDALVRLADSAAGDPSGLRDLGDLDTAAEAETSALAELDADELVS
RAMRGTTFGNH
selected fasta
>polyketide synthase [HbmAII]
ATGGCGAATGACGAAAAGCTCCTCAACTACCTCAAGCGGGTTACCGCCGACCTGCACCAG
ACGCGGGAACGGTTGCGCAAGGCCGAGGCGGCGACGGAGGAGCCGATCGCCATCGTCGGC
ATGGGCTGCCGCTTCCCGGGCGGCGTGACCACCCCAAACGGGCTGTGGGATCTGGTGGCC
GACGGCCGGGACGCGATCGCCGGGTTTCCGGAGGACCGCGGCTGGAACCTGGAGAACCTC
TTCCACGCCGACCCTGACTCCGTCGGCACCTCCTATGTGCGCGAGGGCGGTTTCCTCGCC
GACGCGGCGGAGTTCGACGCCGAGTTCTTCGGCATCTCCCCGCGTGAGGCGCTGGCCACC
GACCCGCAGCAGCGGCTGCTGCTGGAGACCGCGTGGGAGACCCTCGAGCACGCGGGAATC
GACCCGAGTTCGCTGGCGGACAGCGACGTCGGCGTGTTCACCGGCCTGGCCAACGGTGAC
TACGCGCTGACCGTGGACCAGGTGCCGGAGGGGTTCGAGGGATATCTGGGTCTCGGTGGC
GCGGGCAGCATCGCGTCCGGCCGCATCTCGTACTCGCTCGGTCTGCTCGGCCCGGCGGTC
ACTCTGGACACCGGGTGCTCCTCGTCCCTCGTGGCGATGCACTTGGCCAGTTATGCGCTC
CGGTCCGGGGAGTGCTCCATGGCGCTCGCCGGTGGCGTGATGGTGATGGCCACCCCCGGC
GGCTTCGTCGGATTCTCCCGGCAGCGGGGGCTGGCGCGCGACGGGCGCTGCAAGTCCTTC
GGTGAGGGCGCGGATGGCACCAACTGGTCCGAGGGCGCCGGTCTTGTGCTGCTGGAACGA
CTGTCCGATGCCCGCCGCCATGGGCATGAGGTGCTCGCGGTCATCCGTGGCACCGCCGTC
AATCAGGACGGCGCTTCCAACGGCATCACCGCGCCCAACGGCCCGTCCCAGGAACGGGTG
ATCCGCCAGGCACTGGCGAACGCCGGGCTGACGGTGGCCGATGTGGACGCGGTCGAGGCG
CACGGCACCGGCACGAGTCTCGGCGACCCCATCGAGGCCCAGGCGCTCCTGGCCACCTAC
GGCCAGAACCGCCCGGAGGATCAGCCGCTGTGGCTGGGCTCCATCAAGTCCAACATCGGC
CATACCCAGGCCGCCGCGGGTGTCGCGGGCGTCATCAAGATGGTGCAGGCCATGCGGCAT
GGCGTACTGCCCAAGACACTCCACGCCGACGAGCCCACCACCAAGGTGGACTGGTCGCAG
GGTGCGGTGTCGCTGCTGTCCGAGGCCCGGCCCTGGCCGGAGACCGGACACCCCCGCCGC
GCCGGAATCTCCTCCTTCGGCGTCAGCGGGACGAATGCCCATGTGATCCTGGAGCAGGCG
CCGCCTGAGGTGGCCGTGCCCGAAGCAGAGGCCAGCGAGACGGGCACTCCTGGGCTGGTG
GCCACGGGCGGCGTGGTGCCGTGGATGCTGTCGGGTAAGACTCCTGCGGCGCTGCGGGCT
CAGGCCGAGCGTCTGGTCAGCCACCTGGAGTCCGGGAGCGACGCCAACCCGGTCGATGTG
GGCTGGTCGCTGGCCACCACCCGGGCGGCTCTGGATCACCGCGCGGTCATCCTCGCCACG
GATACCGAGGACGGCATCGCCACCGCCCGCGCTTTGGCGGAGGGACGGCCCGACCCGCTC
CTGGTCACCGGGCAGACCGGAACAGACGGCAAGACCGTGTTCGTCTTCCCCGGCCAGGGA
GCCCAGTGGGTGGGCATGGGGGCACAACTCCTCAACACCTCCCCCGCCTTCGCCACCCGG
CTACGCGAGTGTGCCGACGCGCTGGCCCCGTATACCGACTGGTCGCTCATCGACGTCATC
ACCGGCGCACCCGATGCCCCTTCGCTCGACCGTGTCGACGTCGTACAGCCCGCCACCTTC
GCCGTCGTCGTCTCCCTCGCCACCCTCTGGCAATCCATGGGTATCCACCCCGACGCCGTC
ACCGGCCACTCCCAAGGCGAAATCGCCGCAGCCTGCGTCGCCGGACACCTCACCCTCACC
AACGCCGCCAAAATCGTCGCCCTGCGCAGCCAGATCATCGCCGACCACCTCGCCGGACAC
GGCGGCATGATGTCCGTCCTCGCCTCGCGGGAACAGGTCGAGGAAGCCCTCACCCCGTGG
CAGGGCAAGCTCTGGATCGCCGCGCACAACAGCCCCCAGGCGACCGTCGTCGCAGGCGAC
ATCGACGCTCTGCACGAACTCCACGCCCACTACACCGACCAGGACATCCGAGCCCGCATC
ATCCCCGTCGACTACGCCTCCCACACCGGACACGTCGACACCATCAAGAACGAACTCCAC
CAAACCCTGGCCGACACCACCACCGAGCCCGGCACCCTCCCCTGGCTCTCCACCGTCGAC
GGGGAGTGGATCGAACCCGACACGCTCGACAGCGGCTACTGGTACCGGAACCTGCGCCAA
ACGGTGCAGTTCCACACCGCCATCACCACCCTCGCCGACCAGGGCTACCGCACCTACATC
GAAATCAGCCCCCACCCCGTCCTCACCACCGCCATCCAAGAAACCCTCGAAGCCAACGAC
ACCTCCAACACCACCATCACCGGAACCCTCCGCCGCGACGACGACACCCCCACCCGCCTC
CTCACCAACCTCGCCCACCTCACCACCCACGGAACACCCGTCAACTGGCCCACCCTCTTC
ACCGGCACACACCCCACCCGCATCACCCTCCCCACCTACCCCTTCCAACACCACCACTAC
TGGCTCCCCCGCAACACCAGCACAGGCGACATCGCCTCAGCCGGTCTCCACGACCCCGCG
CACCCGCTTCTCACCGCCGCCGTCCACCTCCCCGACACCGGTGGCACCGTCCTCACCGGG
CGGCTCTCCCTGACCACCCACCCCTGGCTGGCCGACCACACCGTGTCCGGTGCCGTCCTC
CTCCCCGGCGCCGCGATGGCCGAACTCGCCATCCGGGCCGGAGACGAGACCGCCACCCCC
ACCCTGGATGAGCTGGTCATCGAGCAGCCACTGGCGCTACCGGACAGTGGCTTCCTGGAC
ATCCGGGTGGTCGTGGGCGGCCCTGACGAGGCCGGGCGTCGGGACGTACGCATCTACTCC
CGCGCCGCAGAAGAATCAGCGCAGTGGACGGTGCACGCCACCGGCACGCTGGCCCAGGAC
ACCACGGCTCCTCCGTCGCCCACCGCCGCCGAATGGCCACCCGCCGGTGCCGAGCCGGTG
GCCGTCGAGGGCCTGTACGAGCAGATGGCCGAGGGGGGCTACGACTACGGACCGACGTTC
CAGGGCCTGAAGGCGGTATGGACCCGCGACGGCGACGTGGGCGAGGTGTTCGCGGAGGCC
GCGCTGCCGGAGGAGCAGACGGAGGCCGCCGGCCGGTTCGGCATCCACCCGGCACTGCTG
GACGCCGCGTTGCACGCGAGCAACTACTGCCTGCCCGGGGAGCCCGGCGGCCGTATGCTG
CTGCCGTTCGCGTGGAACGACATACGCCTGCACGCCACCGGTGCCACTTCGGTGCGCGTA
CACGCCCGTTACACCGAGGACGACGGCCTCTCCGAGGTCCTGGTCGACACGGCCGGAGGG
CTGGTCGCGTCGATCGGTTCGCTGGTTCTGCGGGAGGTCGACGCGGCGCAGCTCGAAGCG
CTGGCCTCCACCTCGGTGAACGACGCGCTGTGGACGGTCACTTGGACCGAACACACCGCC
ACCACGGACGAGATCCGGTGGGGCACCCTAGGGGACGTCTCACCCGTCCTCGCCGCCGCC
GAAGCCCCGGCCTTCGCCGATGTCACAGAGATCGCCACCGCGCCCGCCACGGAGATCGCC
GGGACCGAGGACCGGCCCGCGCTGATCGTCGCCGACACGACAGCATGGCAGTCGCGGGAC
GCCGACCCCATCACGCGGGCGCGCGAACTGGCCACGCGGGCGCTGGACCTGTTGCAGCGG
TGGGTGACGCTGCCTGAGCTGTCGGAAACACGGCTGGCGGTCCTCACCCGCGGTGCGATG
GCCGTACACGACTCGGCCGAGGTCACCGACTCCGCCGCGGCGGCGATCTGGGGTCTGGTC
CGCTCGGCCCAGTCCGAACACCCCGGCCGCATCCAGCTCATCGACGCCGACGGCCACTCG
GACCACACACTGCGCAGCGCACTGTCCACCGCACTCACCACCGACCAGCCCCAACTGGCC
CTCCGCGACAACACGCTCTGGGCGCCCCGGCTCACCCCGACAACACCCGCCGACACACCC
GCCCAGCCGCTCCCTCTCAACCCCGAGGGCACCGTTCTCGTCACCGGCGGCACCGGCACC
CTCGGCGCTCTCACCGCCCGCCATCTCATCACCCACCACGGCGCCCGGCACCTGCTCCTG
ATCAGCCGCCAGGGGCCCGACGCCCCCGGCGCCACCGACCTCACCACCGAACTCACCGAA
CTCGGCGCCACCGTCCACATCACCGCATGCGACACCGCCGACCGCGACCAACTCGCCACC
ACCCTCGCCGACATCCCGGCCGACCACCCCCTCACCGCCGTCATCCACACCGCCGGAACC
CTCGACGACGGCACCCTCACCGCACTCACCCCGAACCGCCTCGACACCGTCTTCCGCCCC
AAGGTCGACGCCATCACCCACCTCCACCACCTCACCCACGACCACGACCTGGCCGCCTTC
GTCATCTACTCCTCCGCCACCGGCACCCTCGGCACCCCCGGTCAGGCCAACTACGCCGCC
GCCAACACCTACGCCGACGCCCTCGTCCACCAACGCCACGCCGCCGGGCTCCCCGCCACC
TCCCTCGCCTGGGGGCTATGGGAAACCACCAGCGCCCTCACCGCCACCATGAACACCGAG
GACCGCCGACGCACCCACCGTGGCGGTGTGGCCGCCCTGACCGACGACGAGGGGCTCGCC
CTCCTCGATAGGGCCCTCACCGCCACCCACCACCCCCACCTCGTCCCGATCAAGATCAGC
CCGGCCTCCCTTCGGGCCGATGACACGGCGCAGCCCGTTCCGCCGCTGCTCCGCCACCTC
GTACGGCGCCCCACGCGCCGTACGGCCCACACACCGGCCCCCGCCGACACCCTGTCGCTC
GCCCAACGGCTCGCCGCCCTCGACCAGGGCGAACGGCTACGGCACCTCACGGAGCTCGTC
CGCACCGAGGCGGCGGCCGTACTCGGACATACGACGATCGACAGCATCGGGCCGGACCAG
CCCTTCCGCGACGTCGGGTTCGACTCCCTCACGGCGGTGGAACTGCGCAACCGCCTCAAT
GCGGCCACGGGACTGCGGCTCCCCGCGACCGTGGTGTTCGACTACCCGACCCCGGCGATC
ACGGCCGGGTATCTGCGGGACGAGCTGTTCGGCCCGGCGGAGGCGGCCCCGGCCGCCGTC
GCCGGGCCGGGGGCCGACGCGGACGATCCCGTGGTCGTCGTCGGCATGGCCTGCCGGCTC
CCCGGACGGGTGACCGACCCGGACGGGCTGTGGCGGCTGGTGGCCGACGGGGAGGACGGC
ATCGGGGCGTTCCCCACCGACCGCGGTTGGGATCTGGACACGCTCTTCGACCCCGACCCG
GACCGGGTGGGCGCGACCTACGTCCGCGAGGGCGGGTTCGTGGCGGGGGCCACCGAGTTC
GACGCGGACTTCTTCGGCATCTCCCCGCGTGAGGCCGTGGCGATGGACCCGCAGCAACGG
CTGCTGCTGGAGACCGCGTGGGAGACCTTCGAGCAGGCCGGTATCGCCCCACGGTCGGTG
CAGGGCAGCGACACCGGTGTGTTCGCCGGGGTCATCTACCACGACTACGGGACGAACGCC
GGTGAGCTGCCCGAGGGCTCGGAGACCTATCTGAGCACGGGCAAATCGGGGAGCGTGGTG
TCCGGGCGGGTGGCCTACGCGCTGGGCCTGACCGGTCCCGCGGTGACGGTCGACACGGCG
TGCTCCTCCTCGCTGGTGGCCATCCACTGGGCGGCCAAGGCGGTGCGGGAGGGCGAGTGC
TCGATGGCCCTGGCCGGGGGCGTGACGGTGATGTCGACCCCGGATGGGTTCGTGAGCTTC
TCGCACCAGCGCGGGCTCGCCCCCGACGGCCGCAGCAAGTCCTTCGGCGAGGGCGCCGAC
GGCACCACCTTCAGCGAGGGCGTCGGGCTCGTGCTGCTGGAGCGGCTCTCCGAGGCGCGG
CGCAACGGTCACGAGGTGCTGGCCGTGGTCCGCGGTACGGCGGTCAACCAGGACGGCGCC
AGCAACGGCCTCACCGCCCCCAACGGCCCCTCCCAGCAACGGGTGATCCGCCAGGCCCTG
TCCAGTGCCGGACTGTCGGCGACCGACATCGACGCCGTCGAAGCCCACGGCACCGGCACC
GCCCTCGGCGACCCCATAGAAGCACAAGCGCTGCTGGCCACCTACGGCCAGGACCGCCCC
GCCGACCAGCCCCTCTGGCTGGGCTCACTGAAGTCCAACATCGGCCACACCCAGGCCGCC
GCGGGCATCGCGGGCGTCATCAAGATGATCCAGGCCATGCGGCACGGCATGCTGCCCAGG
ACACTCCACGCCGACGAGCCCACCACCAAGGTCGACTGGACGTCGGGCGCGGTGTCCCTG
CTCACCGAGGCCAGGCCCTGGCCGGAGACCGGACACCCCCGCCGCGCCGGAATCTCCTCC
TTCGGCGTCAGCGGCACCAACGCCCATCTCATCCTCGAACAGGCCCCGGAGGAGGCGGCC
ACCGCACCAGAGACCACGGAGCCGGAGGCTCCCGGGCTGGTGGCCACGGGCGGCGCGGTG
CCGTGGGTGCTGTCCGCCAAGAGCCCAACGGCCCTGCGGGCGCAGGCCGAACGCCTGATC
GCCCACCTTCACGCCCACCCCGAGACCGACCCGGTGGACATGGGCTGGTCGCTGGCCACC
AGCCGCGCCGCCCTGGAACACCGGGCGGTCGTCCTCGCCACCGATCTCGACCAGGCGACC
GCCGCCCTCACCGCCCTCAGCGAAGGGCAGCCGCACCCCAGCCTGATCACCGGGGAGACC
GGCAGTGATGGCAAGACCGTGTTCGTGTTCCCCGGCCAGGGCGCCCAATGGGCAGGCATG
GGAGCCCAACTCCTCGACACCTCACCCGTCTTCGCCACCCGCCTCCACGAATGCGCCGAA
GCTCTCGCCCCCTACACCGACTGGTCACTCATCGACGTCATCACCGGCGCGCCTGATGCC
CCTTCGCTCGACCGCGTCGACGTCCTCCAGCCCACCACCTTCGCCATCATGGTCTCCCTC
GCCGCACTCTGGCAGGCCAACGGCATCCACCCCGACGCCGTCATCGGCCACTCCCAAGGC
GAAATCGCCGCAGCCTGCGTCGCCGGACACCTCACCCTCACCAACGCCGCCAAAATCGTC
ACCCTCCGCAGCCAGACCATCGCCCACCACCTCACCGGACACGGCGCCATGATGTCCGTC
CTCGCATCCCCCACCTGGGTCCAGGAAACACTCGCACCCTGGCACGGACACCTATGGATC
GCCGCCGTCAACGGCCCCGCATCCGTCTCCGTATCCGGAGACCCCGACGCACTCGCCGAA
TTCGGCACCACCCTCTCCAAAGCCAAGGTCTACCGCTGGCAACTCCCCGGCGTCGACTTC
GCCGGACACTCCGGACACGTCGACACCATCAAAGACCAGTTGCACAACGTACTCGACGGC
ATCACCGCCACACCCGGCCACACCGCCTGGATGTCCACCGTCGACGCCGACTGGGCCAAC
CCCACACACATCGACCCCGACTACTGGTACCGCAACCTCCGCGACACCGTCCGCTTCGAA
GAAGCCACCCGAGCCCTCCTCACCCACGGCCACCGCGTCTTCATCGAAGTCAGCACCCAC
CCCGTCCTGACCACCGCCATCCAAGAGACCACCGAAACCCTCCCCGAAGTCCGGGCCACC
ATCACCGGGACGCTGCGCCGCGACGACGGCGCCGCGGACCGCGTTCTCGCGGGGCTGGGC
GGGCTGTTCGCGGCCGGGGTGCCGGTGGACTGGGGCGCTCTGTTCGCCGGTACCGGGGCC
CGCCGGGTGCCGCTGCCCACGTACGCCTTCCAGCACCGGCACTACTGGCTGGAGCCCGCC
AGGACCCCGACGCGGGCCGAGACCGCCGACGGCTCCCTGTGGGCGGCCATCGAGGACGGC
GACACGCAGTCCCTCGCACGGGATCTCGAGGTGGACGCGGCGGCCCTCGGCACGGTGCTG
CCCGCGCTGGCCTCATGGCGTCGGCGCAGCCGGGAGGATTCCCTCACGGACGCATGGCGG
TACCGGATCGGCTGGACCCGGGTGGCCGCGGCCGATCCACAGATGTCGGGCCGGTGGCTG
GTGCTGGTCCCGGCCGTGCGGGCGGGCTCGGCGCGGGTCCGAGCGGTGCTGGACGGGCTG
GCCGCGCGGGGCGCCGAGGTGGTGGCCGCCGAGGTCTCCGAGACCGGCCGGGAGGCGCTG
GGCGACCAGGTCAAGTCGGCGGACGGCGGTGCCGGGGTGGTGTCCCTGCTCTCGTGGGAC
GACCGCGCCGACACCGAGTACGGCACCGTGTCCACGGGCACCGCGGCCACGCTCGCGGCG
GCGCAGGCGTTGCGGGACCACGGCATCACCGCCCCGCTGTGGTGCGTCACCAGTGGCGGG
GTCGCGGTGGCCGGTGAGACGGCCGACCCGGTGCAGTCGGCGGTGTGGGGATTCGGCGCC
GTGCTCGGGCTCGACCACCCGGACACCTTCGGCGGCCTGATCGACCTGCCGGCCGAAAGG
GAGGGTGACGGCGAGGCGCTGCCGGACGGGCTGTTCGCGGCGCTGTCGTCTCCGGAGGGG
GAGGACCAGCTCGCGGTGCGCGCCGACGGGCTGTTCGCACGCCGGATGGTGCGCGACCGG
GACGGCTCCGGCAGCCTCTGGAAGCCACGCGGCACCGTGCTGGTCACGGGCGGCACCGGC
GGGCTCGGCTCGCATGTGGCGCGCTGGCTCGCCACGAGCGGGGCGGACCATGTGGTGCTG
CTCAGCAGGCAGGGCGGTGACGCGCCGGGCGCGGCCGAACTGGTGGCGGACCTGGCGGGG
GTGCAGGTCACGCTCGCCGCCTGTGATGTGACCGACCGGGAGGCCGTGGCCGCGGTGCTG
GCGGAGGCGGAGCGGACCCATCCGCTGACCGCGGTGGTGCACACCGCCGGTGCCGGGCTG
CCCTCGGCTCCGGTCACCGAGGTGACCGCCGAGGAGTTCGCCGCCGTGACGGGGGCGAAG
GTGCGCGGGGCGCTGGTGCTGGACCAGCTCGTCGGCGATCGGCAGCTCGACGCGTTCGTG
CTGTTCTCCTCCGGCGCCGGTGTCTGGGGCAGTGGCGGGCAGGCCCCGTACGCGGCGGGC
AACGCCTTCCTGGACGGGCTGGCGGCCCGGCGGCGGGCCCACGGGCTGGCGGCCACATCG
GTGGCGTGGGGCGGCTGGGGCGGCGGGCTCGGCATGATCGACGCCGACGGCGGCGATCAG
TGGCGCCGTATCGGCATCCTGCCGATGGATCCGGCGCCCGCGTTGCGTGCGATGGCGCGG
GCAGTGGGCAGTGGTCTGCCGAATGCGATTGTCGCGGACGTCGACTGGGCGCGGTTCGTG
CCGGGATACACGATGGCCCGGGAGCGGCCGCTGCTGCGGCAGTTGCCCGAGGTCGCCGAG
ATCCTGGCGGCGGACGCGCGGGGCGGGGGCGCATCGCGGCGGGAGGTGCTTCTGGGCAGC
CTGGCCGAGCTGACCGGCCCGGAGCAGGAGGTGTTCCTGACCGATCTGGTGCGGCGTGAG
GCGGCGGCCGTGCTCGGGCATGCGGACGGGGACGCGGTGGAGCCGGAGCGTGCGTTCAAG
GACACCGGGTTCGACTCGCTGACCGCGGTGGAGCTGCGCAACCGGATCAACGCGGCCACC
GGGCTCCAGCTCTCCCCCACGGTGGTGTTCGACTATCCGAAGCCGACCACGCTGGCGAGG
AGGCTGCGTACGGAGCTGGTCCCCGCCGTGAATGGGGACGCGAACGGGGGCATGGACGGG
GACGGGACCGCGGATGGCGGGGCCGTCGGCGCGGAGGGCCGCGAGCGGCAGATCCGGCGG
GTGCTGGCCTCGGTGCCGTTACGCCGCTTCCACGAGCTGGGGGTGCTGGACGCGCTGGTG
CGCCTCGCGGACTCCGCGGCCGGTGACCCGAGCGGTCTGCGCGACCTGGGCGACCTGGAC
ACCGCCGCGGAGGCGGAGACCTCCGCGCTCGCGGAGCTGGATGCCGACGAGCTGGTGAGC
CGGGCGATGCGCGGCACGACCTTCGGAAACCACTGA
[4] KS34..409
[4] AT573..893
[4] methylmalonyl-CoA765..769
[4] DH941..1103
[4] KR1430..1610
[4] ACP1716..1786
[5] KS1809..2184
[5] AT2347..2668
[5] methoxymalonyl-ACP2540..2544
[5] KR2971..3149
[5] ACP3253..3323
[4] KS100..1227
[4] AT1717..2679
[4] methylmalonyl-CoA2293..2307
[4] DH2821..3309
[4] KR4288..4830
[4] ACP5146..5358
[5] KS5425..6552
[5] AT7039..8004
[5] methoxymalonyl-ACP7618..7632
[5] KR8911..9447
[5] ACP9757..9969

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR001227 Acyl transferase domain (Domain)
[565-696] G3DSA:3.40.366.10 [765-883] G3DSA:3.40.366.10 [2335-2470] G3DSA:3.40.366.10 [2540-2656] G3DSA:3.40.366.10
G3DSA:3.40.366.10   Ac_transferase_reg
IPR006162 Phosphopantetheine attachment site (PTM)
[1744-1759] PS00012 [3281-3296] PS00012
PS00012   PHOSPHOPANTETHEINE
IPR009081 Acyl carrier protein-like (Domain)
[1716-1786] PS50075 [3253-3323] PS50075
PS50075   ACP_DOMAIN
[1719-1780] 3.7e-13 PF00550 [3256-3322] 9.40000000000003e-11 PF00550
PF00550   PP-binding
[1715-1789] 4.30000000000003e-44 G3DSA:1.10.1200.10 [3253-3326] 4.30000000000003e-44 G3DSA:1.10.1200.10
G3DSA:1.10.1200.10   ACP_like
[1709-1825] 9.00000407957274e-28 SSF47336 [3245-3340] 1.20000117458134e-19 SSF47336
SSF47336   ACP_like
IPR013968 Polyketide synthase, KR (Domain)
[1430-1609] 1.70000000000001e-60 PF08659 [2971-3148] 3.7e-58 PF08659
PF08659   KR
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
[34-284] 3.99999999999998e-92 PF00109 [1809-2059] 3.49999999999995e-91 PF00109
PF00109   ketoacyl-synt
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
[292-409] 1e-49 PF02801 [2067-2184] 1.99999999999999e-48 PF02801
PF02801   Ketoacyl-synt_C
IPR014043 Acyl transferase (Domain)
[573-893] 2.90000000000003e-103 PF00698 [2347-2668] 3.60000000000002e-98 PF00698
PF00698   Acyl_transf_1
IPR015083 Polyketide synthase, docking (Domain)
[1-26] 2.1e-13 PF08990
PF08990   Docking
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
[571-874] 2.7000136937899e-67 SSF52151 [2345-2649] 1.20000117458134e-63 SSF52151
SSF52151   Acyl_Trfase/lysoPlipase
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
[699-764] 7.49999605851445e-19 SSF55048 [2473-2539] 2.39999798157265e-13 SSF55048
SSF55048   Malonyl_transacylase_ACP-bd
IPR016038 Thiolase-like, subgroup (Domain)
[33-295] G3DSA:3.40.47.10 [296-463] G3DSA:3.40.47.10 [1808-2070] G3DSA:3.40.47.10 [2071-2239] G3DSA:3.40.47.10
G3DSA:3.40.47.10   Thiolase-like_subgr
IPR016039 Thiolase-like (Domain)
[26-408] 2.1000026783403e-102 SSF53901 [1801-2237] 6.90004508941104e-101 SSF53901
SSF53901   Thiolase-like
IPR016040 NAD(P)-binding domain (Domain)
[1430-1640] 2.39999999999997e-71 G3DSA:3.40.50.720 [2971-3150] 2.39999999999997e-71 G3DSA:3.40.50.720
G3DSA:3.40.50.720   NAD(P)-bd
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
[197-213] PS00606 [1972-1988] PS00606
PS00606   B_KETOACYL_SYNTHASE
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
[575-874] 1.50000965748778e-122 SM00827 [2349-2649] 2.0000139277205e-112 SM00827
SM00827   PKS_AT
IPR020806 Polyketide synthase, phosphopantetheine-binding domain (Domain)
[1717-1789] 8.20001307135067e-36 SM00823 [3254-3326] 3.49999466863949e-33 SM00823
SM00823   PKS_PP
IPR020807 Polyketide synthase, dehydratase domain (Domain)
[941-1103] 2.39999798157263e-84 SM00826
SM00826   PKS_DH
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain (Domain)
[36-462] SM00825 [1811-2237] SM00825
SM00825   PKS_KS
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
[1430-1610] 1.40000506907309e-56 SM00822 [2971-3149] 1.40000506907309e-49 SM00822
SM00822   PKS_KR
SignalP
[1-30] 0.159 Signal
Bacteria, Gram-positive   
TMHMM No significant hit
Herb_00170 Herb_00170   Herb_00190 Herb_00190
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