Herb_00180 Herb_00180   Herb_00200 Herb_00200

Herb_00190 : CDS information

close this sectionLocation

Organism
StrainAM 3672
Entry nameHerbimycin A
Contig
Start / Stop / Direction58,519 / 70,125 / + [in whole cluster]
58,519 / 70,125 / + [in contig]
Location58519..70125 [in whole cluster]
58519..70125 [in contig]
TypeCDS
Length11,607 bp (3,868 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category1.1 PKS
Productpolyketide synthase
Product (GenBank)HbmAIII
Gene
Gene (GenBank)hbmAIII
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[16085885] Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption. (Appl Environ Microbiol. , 2005)
comment
herbimycin生合成系gene clusterのクローニングを行い、同じbenzoquinone ansamycin系のgeldanamycin のgene clusterと比較し、一部の遺伝子欠損株を作成してその生合成における関与を調べた文献。

HbmAIII(11,607bp):PKS modules 6 and 7
Module 6 (KS-AT-DH-ER-KR-ACP)
Module 7 (KS-AT-DH-KR-ACP)

hbmAIII自体の機能実験は無し。

close this sectionPKS/NRPS Module

6 malonyl-CoA
7 methylmalonyl-CoA
KS35..410
AT584..907
DH954..1122
ER1431..1731
KR1741..1921
ACP2023..2093
KS2120..2495
AT2664..2982
DH3029..3193
KR3503..3683
ACP3789..3859

close this sectionSequence

selected fasta
>polyketide synthase [HbmAIII]
MAASREDLVKALRTSLMDAERLRRENDRLIAESTEPVAIVAMACRLPGGVTDPESLWKLV
DEGRDAIGPFPTDRGWDLETLFDADPDAVGKSYVREAGFLEGAGGFDAAFFGISPREALS
LDPQQRLLLETAWETFERAGMDPRSVEGRDIAVFAGGSGQGYGGGPGDAPKGLEGYLGVG
ASGSVISGRVSYTLGLTGPAVTVDTACSSSLVAAHLAVQALRSGECSMALAGGVAVMGQP
TAFVEFSRQRGLAPDGRCKSFGEGADGTTWSEGVGLVLLERLSDARRNGHDVLAVIRGTA
VNQDGASNGLTAPNGPSQERVIRQALSNAGLTVADVDAVEAHGTGTALGDPIEAQAVLAT
YGRKRPADQPLWLGSLKSNIGHAQAAAGIASVIKTVMALRHGRLPKTLHAEQPTSQVNWT
SGAVSLLTEARAWPETGHARRAGISSFGVSGTNAHVILEQAPEEAEATGENTAGQEPSVR
SAESADPGPVATGQVVPWVLSGHTREALRAQAARLLTQVRETPADGLRDVGWSLATTRTR
LDHRAVVLCADAEQAVAGLEAVASGASARSAVSGSVAAGKVAVLFTGQGSQRAGMGRELH
GGYPVFARAFDAVCAQFGDLPDGDDKVSLAEVVFAEEGSARAALLDRTEFTQPALFALEV
ALFRLVESWGVRPAYVLGHSIGEVAAAHVAGVLSLPDACTLVRARGRLMQRLTATGAMVA
VEAAEDEVAPLLAGKEHKVSIAAVNGPTSVVVSGDEDVVTAVAETLARQGRKTKRLVVSH
AFHSPHMDGMLDAFREVASRLTYAPPRIPVVSNLTGTVAEPGELCSPEYWVRHARGAVRF
LDGVRTLADQGVRTHLELGPDGVLTAMGQDCLPEADAAFVPSLRPGVQEPHAVLAGLAGL
YVRGVRVDWDAMFAGSGARRVALPTYAFQHEHYWLERAAGSGDVGAVGLGEAGHPLLGAV
VQLPETGGVQLSGRLSVRAQPWLGEHVISGAVLVPGTAMVELAVRAGDETGTPVLEELVI
GQPMVLPGDTALSVQVVVGADEGGRRTVRIYSRTDGGSDWTEHATGTLAAQGPAPLDGGA
YGAGDGAAVQWPPAEAEPIPVEDFYRSLVDAGYAYGPAFRGLVAAWRRDGEIFGDVALPE
ASVAEAERFGIHPALLDAALHAGSFCLPSDPARQVTLLPFAWNNVRLHAGGASAVRVHVR
PVGDDAFSVRLTDGSGQTVASVDSLTLRAVDPAQLEIGTADDALWTVRWSETSLPDGAIS
WAALGDPATGGAGAMGDTGSAGGALPDVLVADTRAWAEDLTGPPTARARRLTGRLLAEIQ
RWVADDAMAGTRLAVVTRGAVAVRDDAEVTDPAATAVWGLVRSAQAEHPGRVALVDADGV
CEELPAGVWSGEEPQLAVRGGAVWVPRLARVEPGLRVPAQASWHLDSAEYGTLDHLALLP
DEAEPAPLEAGQVRIEVRAAGLNFRDVLVALGMYPGRSVIGTEGSGVVTEVGPGVAELAV
GDRVMGLFSGSFGPLATADAHTVIRMPDGWSFGTAAGVPVAYLTALYALQDLGSVQPGET
VLVHAAAGGVGMAAVQLAQHFGATVLGTAHPSKHHALHRLGVPAERLASSRDLGYAAAFP
TADVVLNSLTGEHIDASLGLLNPGGRFLEMGKTDLREPGEVGARHPEVTYRAFDLGGEAP
AERVRELLHQLVELFEAGRIEPLPVRQWDITRAPEAFRWMSQGRHTGKIVLTLPRALDPD
GTVLVTGGTGTLGATVARHLVTQHGARRLLLVSRRGPDAPGATDLTTELTELGATVHITA
CDTADRDQLATTLADIPADHPLTAVVHTAGTLDDGILTALTPDRLDTVFRPKVDAITHLH
DLTRDQDLAAFVVYSSAAGVLGGPGQGNYSAANAYLDGLAQWRRAHGLPATSLAWGMWAQ
TSGMTAGLGSGDLHRVRRGGIVGLSTAEALDLFDRSVASGLSLLVPLRFDLAALGAEAAE
PPPLLRGLVRPARRTARPVPKAGEGGLVERLAGLSAAEQERLLVELIREQAASVLGFPTV
DPIGPEQAFRDMGFDSLTAVELRNRLNTATGLRLPATLVFDHPTPLATAELLRDELGGRA
VEATPRPARRDRSAPDAAEDPVVVVGMGCRLPGDVRTPEDLWRLVAAGTDAIGPFPQDRG
WDLAGLFDSDPDALGKSYVREGGFLTDAGGFDATFFGISPREALSMDPQQRVLLETAWET
LERSGIVPTSLRGQEVGVFVGASGQGYGTGPGAAPEGLEGYLGVGGATSVASGRLSYTFG
LTGPAVTVDTACSSSLVALHLAAQALRSGECTMALAGGVAVMGQPGAFVEFSRQRGLASD
GRCKSFGEGADGTNWSEGAGLVLLERLSDARRNGHEVLAVIRGTAVNQDGASNGLTAPNG
PSQQRVIRQALSNAGLTVADVDAVEAHGTGTALGDPIEAQALLATYGQDRPGDEPVWLGS
LKSNIGHTQAAAGISSVIKMVLAMRQGTLPRSLHADEPTTQVDWTSGAVSLLTEARPWPE
TGHLRRAGISSFGVSGTNAHVVLEQAPEAAAPQADEADDIPGLVATGGIAPWVLSAKTPT
ALRAQAQRLLDHLESGVDGRPLDIGWSLATTRTLHDHRAIILTDTDTDTRAEGGEATAAL
TALVTGQPHPRLTTGYATTQGKTVFVFPGQGSQWVGMGAQLLDTSPVFAARLRECADALA
PYTDWSLMDVITGAPDAPSLDRVDVVQPATFAVVVSLATLWQSMGIHPDAVTGHSQGEIA
AACVAGHLTLTNAAKIVALRSQIIADHLAGHGGMMSLATPADTIDLTNWHGKLWIAAHNG
PNATVIAGDAEALHQLHAHYTDQGIRARIIPVDYASHTGHVDTIKNELHQTLADTTTEPG
TLPWLSTVDGEWIEPNTLDSTYWYRNLRQTVQFHTAITTLADQGYRTYIEISPHPVLTTA
IQETLETHNTPNAIVTGTLRRDDDTPTRLLTNLAHLTTHGTPVNWPTLFTGTHPTRITLP
TYPFEQETFWLDRSGPGDVRAVGLEDTGHPLVGAVVSVPDTDGVLLTGRLSLTTHPWLAD
HAVSGTVLLPGTAMVELAVRAGDEAEARVLEELIISRPMAVPDEGTLHVQVLVGGEEGDE
GGRRKVGVYSRPEGIRQWTEHATGTLLTGGTATAAATTAHPWPPEGAEPVALEGFYEQLA
EAGYEYGPAFRGLSAVWKRDDEVFAEVAVPEDQTAVAGRFGIHPALLDATLHAGNFCFES
GGDRPTMLPFAWTDVRLHAVGATAVRVRATASGTDGLCVQITDPHGLPVATIGSLQLRET
TPEQLRALSATSGGNALWAVEWAECGLDDTTEAQWATLGESQLLDSPLHYADVSQVVAAG
EQPAALVADVSAWAPENTGPPIDRAHALCARVLDLLRQWVDRPEPADTRLVILTRGAMAV
HDTAEVTDAAAAAVWGLVRSAQSEHPGRIQLIDIDEHSHRTLPTALTTTDQPQLALRDAT
AYTPHLAPAPTPTPGPLTLAPEGTVLITGGTGTLGALTARHLITHHKARNLLLVSRQGPD
APGADRLSEELTQLGARIRIAACDVADRDQLATVLATIPADQPLTAVIHTAGALDDALLT
DLTPERLGTVFRPKVDALTHLHDLTRDHDLAAFVIYSSATGALGTPGQANYAAANTYADA
LAQQRHAAGLPATSLAWGLWETTSALTAGMSTTHQQRTRHSGVIPLTDADGMRLLDTALT
THQPHLIPLKLDRTALRNSAASHTLPPLLRTLAQSHHRPTAHTTPRTAAAPPLPEQLAAL
DPAQRLQHLTAFVRAEAAAVLGHATSDAVGPDDPLFEIGFDSLTAVELRNRLNAATGLQL
PAALLFDHPTPAMAAEHLQEQLALKDAS
selected fasta
>polyketide synthase [HbmAIII]
ATGGCTGCGTCCCGGGAAGACCTGGTCAAGGCGCTGCGTACCTCGCTGATGGACGCCGAG
CGGCTGAGGCGGGAGAACGACCGGCTGATCGCCGAGTCCACCGAACCGGTGGCGATCGTG
GCGATGGCGTGCCGGCTGCCGGGCGGGGTGACCGACCCGGAGTCGCTGTGGAAGCTGGTG
GACGAGGGGCGGGACGCGATCGGGCCGTTCCCCACGGATCGCGGCTGGGACCTGGAGACG
CTGTTCGACGCCGATCCGGACGCCGTGGGCAAGTCCTACGTACGCGAGGCGGGATTTCTG
GAGGGGGCGGGCGGGTTCGACGCCGCGTTCTTCGGCATCTCGCCGCGCGAGGCCCTGTCG
CTGGACCCGCAGCAGCGGCTGCTGCTGGAGACCGCGTGGGAGACCTTCGAGCGGGCGGGG
ATGGATCCGCGGTCGGTGGAGGGCCGGGACATCGCGGTGTTCGCCGGGGGCAGCGGCCAG
GGGTACGGCGGCGGTCCGGGTGACGCGCCCAAGGGCCTGGAGGGTTATCTGGGGGTCGGG
GCTTCCGGCAGTGTCATCTCCGGGCGTGTGTCGTACACGCTCGGGCTGACCGGGCCCGCC
GTCACCGTGGACACCGCCTGCTCGTCCTCGCTGGTGGCCGCCCATCTCGCCGTACAGGCC
CTGCGGTCGGGCGAATGCTCCATGGCGCTGGCCGGTGGTGTCGCCGTGATGGGCCAGCCC
ACCGCCTTCGTCGAGTTCTCCCGGCAGCGTGGCCTGGCGCCCGACGGGCGCTGCAAGTCC
TTCGGCGAGGGCGCCGACGGCACCACCTGGTCCGAAGGTGTCGGGCTCGTGTTGCTGGAG
CGGCTGTCCGACGCCCGCCGCAACGGCCACGACGTGCTGGCCGTGATCCGGGGCACCGCG
GTCAACCAGGACGGCGCCTCCAATGGCCTCACCGCGCCCAACGGCCCCTCCCAGGAGCGG
GTGATCCGGCAGGCCCTGTCCAACGCCGGGCTGACGGTGGCCGACGTGGACGCGGTCGAG
GCTCACGGCACCGGCACCGCCCTCGGCGACCCCATCGAAGCCCAGGCCGTTCTCGCCACC
TACGGCCGGAAACGCCCCGCCGACCAGCCCCTCTGGCTCGGCTCCCTCAAGTCCAACATC
GGCCACGCACAGGCCGCCGCGGGCATCGCCAGTGTCATCAAGACCGTCATGGCCTTACGC
CACGGCCGGCTGCCGAAGACCCTCCACGCCGAACAGCCCACCTCCCAGGTGAACTGGACG
TCGGGCGCGGTGTCCCTGCTCACCGAGGCGCGGGCGTGGCCGGAGACCGGACACGCCCGC
CGCGCCGGGATCTCCTCCTTCGGCGTCAGCGGAACGAACGCCCACGTCATCCTGGAACAG
GCCCCCGAGGAAGCCGAGGCGACCGGGGAGAACACGGCCGGTCAGGAACCGTCCGTACGC
TCGGCGGAGTCCGCCGACCCCGGTCCGGTGGCCACCGGCCAGGTGGTGCCGTGGGTGCTC
TCGGGCCATACGCGGGAGGCGCTGCGTGCCCAGGCCGCCCGGCTGCTGACCCAGGTACGG
GAGACGCCCGCCGACGGCCTCCGGGACGTGGGCTGGTCACTGGCCACCACCCGGACCCGG
CTGGACCACCGCGCGGTCGTGCTGTGCGCCGATGCCGAGCAGGCCGTCGCGGGGCTGGAG
GCGGTGGCCTCGGGCGCGTCCGCCCGGTCGGCGGTCAGCGGGTCCGTGGCCGCCGGAAAG
GTGGCGGTGCTGTTCACCGGGCAGGGCAGCCAGCGAGCCGGAATGGGCCGTGAACTGCAC
GGCGGCTACCCGGTGTTCGCGCGGGCCTTCGACGCCGTGTGCGCCCAGTTCGGCGACCTG
CCCGACGGGGACGACAAGGTCTCGCTCGCCGAAGTGGTCTTCGCCGAGGAGGGGTCGGCG
AGGGCAGCGCTGCTGGACCGGACCGAGTTCACCCAGCCCGCGCTGTTCGCGCTGGAAGTG
GCGCTGTTCCGGCTCGTGGAGTCGTGGGGAGTGCGCCCCGCGTATGTGCTGGGCCACTCG
ATCGGCGAAGTGGCCGCGGCCCATGTGGCCGGGGTCCTGTCCCTGCCGGACGCCTGCACA
TTGGTACGGGCGCGCGGGCGGCTGATGCAGCGACTCACCGCGACCGGGGCGATGGTCGCG
GTGGAGGCGGCCGAGGACGAGGTGGCGCCGCTGCTCGCGGGGAAGGAGCACAAGGTCTCC
ATCGCCGCGGTCAACGGCCCGACCTCCGTGGTCGTCTCCGGTGACGAGGACGTGGTCACG
GCGGTGGCGGAGACGCTGGCGCGGCAGGGCCGCAAGACCAAGCGGCTCGTGGTCTCGCAC
GCCTTCCACTCCCCGCACATGGACGGGATGCTGGACGCGTTCCGCGAGGTGGCGTCCCGG
CTGACCTACGCGCCGCCACGGATACCCGTGGTGTCGAACCTCACCGGCACGGTCGCCGAA
CCCGGGGAGCTGTGCTCCCCCGAGTACTGGGTACGGCATGCGCGGGGCGCGGTGCGGTTC
CTCGACGGTGTCCGCACACTGGCCGATCAGGGCGTGCGCACCCATCTGGAACTCGGCCCG
GACGGGGTGCTGACCGCGATGGGGCAGGACTGTCTGCCCGAGGCGGACGCGGCGTTCGTG
CCGTCCCTGCGTCCGGGTGTCCAGGAGCCCCACGCGGTGCTGGCCGGGCTCGCCGGGCTG
TACGTACGGGGTGTACGGGTGGACTGGGACGCGATGTTCGCCGGGTCCGGCGCCCGGCGC
GTCGCCCTTCCCACGTACGCCTTCCAGCACGAGCACTACTGGCTGGAGCGGGCCGCCGGA
TCCGGTGACGTGGGCGCGGTGGGGCTCGGGGAGGCGGGCCATCCGCTGCTGGGCGCGGTG
GTGCAGCTCCCGGAGACGGGCGGGGTGCAGCTCAGCGGGCGGCTGTCGGTACGGGCCCAG
CCCTGGCTGGGCGAACACGTCATCTCCGGGGCGGTGCTGGTGCCCGGCACGGCCATGGTG
GAACTGGCCGTCCGCGCCGGGGACGAGACCGGCACCCCGGTGCTGGAGGAGCTGGTGATC
GGGCAGCCGATGGTGCTGCCCGGCGACACCGCCCTGAGCGTCCAGGTCGTCGTGGGCGCG
GACGAGGGCGGGCGGCGTACGGTGCGGATCTACTCCCGTACCGACGGGGGCAGCGACTGG
ACCGAGCACGCCACCGGCACACTCGCGGCGCAGGGCCCGGCACCGCTGGACGGGGGCGCG
TACGGAGCCGGGGACGGGGCCGCCGTCCAGTGGCCGCCCGCGGAAGCCGAGCCGATCCCG
GTGGAGGACTTCTACCGCTCGCTCGTCGACGCCGGATACGCGTACGGTCCGGCGTTCCGT
GGGCTCGTCGCCGCGTGGCGCCGGGACGGTGAGATCTTCGGCGATGTGGCGCTGCCGGAG
GCGTCCGTCGCGGAGGCCGAACGGTTCGGCATCCACCCGGCGCTGCTGGACGCCGCGCTG
CACGCGGGCAGCTTCTGCCTGCCCTCGGACCCGGCGCGACAGGTGACCTTGCTGCCGTTC
GCCTGGAACAACGTGCGTCTGCACGCGGGCGGCGCGTCCGCGGTCCGGGTGCATGTCCGC
CCGGTCGGCGACGACGCCTTCTCGGTACGTCTGACCGACGGCTCGGGCCAGACGGTGGCC
TCCGTGGACTCGCTCACCCTGCGCGCGGTGGATCCGGCCCAACTGGAGATCGGTACGGCC
GACGACGCGCTGTGGACGGTCCGTTGGAGCGAGACCTCCCTGCCGGACGGCGCGATCTCC
TGGGCCGCGCTGGGCGATCCGGCCACCGGTGGCGCCGGGGCCATGGGAGACACCGGAAGC
GCGGGAGGCGCCCTTCCCGACGTCCTCGTGGCCGATACGCGCGCCTGGGCCGAAGACCTC
ACCGGGCCGCCGACCGCGCGGGCCCGCCGGCTCACCGGCCGCCTGCTGGCGGAGATCCAG
CGGTGGGTCGCCGACGACGCGATGGCCGGGACCCGGCTGGCCGTGGTCACCCGCGGTGCG
GTCGCGGTGCGCGACGACGCCGAGGTCACCGACCCGGCCGCCACCGCGGTCTGGGGCCTG
GTCCGCTCGGCCCAGGCCGAACACCCGGGGCGGGTGGCCCTGGTGGATGCCGACGGGGTG
TGCGAGGAGCTGCCCGCCGGGGTGTGGTCCGGGGAGGAGCCCCAACTGGCGGTGCGCGGT
GGCGCCGTGTGGGTGCCGCGCCTGGCCCGGGTCGAGCCCGGTCTGCGCGTGCCCGCGCAG
GCGTCGTGGCATCTGGACTCGGCCGAGTACGGCACTCTGGACCATCTGGCGCTGCTGCCC
GACGAGGCCGAGCCCGCACCGCTGGAAGCGGGTCAGGTGCGGATCGAGGTCCGCGCCGCC
GGGCTCAACTTCCGGGATGTCCTGGTGGCTCTCGGCATGTATCCGGGCCGGTCGGTGATC
GGCACGGAGGGCTCCGGTGTGGTGACCGAGGTCGGTCCGGGCGTCGCGGAGCTGGCCGTG
GGCGACCGGGTGATGGGCCTGTTCTCCGGCTCGTTCGGGCCGCTGGCCACCGCCGACGCG
CATACGGTGATCCGGATGCCGGATGGCTGGTCGTTCGGCACGGCGGCCGGGGTGCCGGTG
GCCTATCTGACGGCGCTGTACGCGTTGCAGGACCTCGGGAGCGTTCAGCCGGGCGAGACG
GTCCTGGTGCACGCCGCCGCGGGCGGTGTGGGCATGGCCGCCGTCCAGCTCGCACAGCAC
TTCGGCGCCACCGTCCTGGGCACCGCCCACCCCTCCAAGCACCACGCACTCCACCGGCTT
GGCGTGCCCGCCGAACGGCTCGCCTCCAGCCGCGACCTCGGCTACGCCGCCGCCTTCCCC
ACCGCCGACGTCGTGCTCAACTCCCTCACCGGCGAGCACATCGACGCCTCTCTCGGACTT
CTCAATCCCGGCGGCCGGTTCCTGGAGATGGGCAAGACCGACCTGCGGGAGCCCGGCGAG
GTCGGGGCACGGCATCCGGAGGTCACCTACCGGGCGTTCGACCTCGGCGGGGAGGCCCCC
GCGGAGCGGGTGCGGGAGTTGCTGCACCAGTTGGTGGAGCTGTTCGAGGCGGGCCGGATA
GAGCCGCTTCCGGTGCGGCAGTGGGACATCACCCGCGCCCCCGAGGCGTTCCGCTGGATG
AGCCAGGGGCGGCACACCGGCAAGATCGTGCTCACCCTCCCCCGCGCCCTGGACCCGGAC
GGCACCGTCCTGGTCACCGGCGGCACCGGAACCCTCGGCGCCACCGTCGCCCGCCACCTC
GTCACCCAGCACGGCGCACGCCGACTACTGCTGGTCAGCCGCCGGGGACCGGACGCACCC
GGCGCCACCGACCTCACCACCGAACTCACCGAACTCGGCGCCACCGTCCACATCACCGCA
TGCGACACCGCCGACCGCGACCAACTCGCCACCACCCTCGCCGACATCCCGGCCGACCAC
CCCCTCACCGCCGTGGTCCACACGGCCGGGACGCTCGACGACGGCATCCTCACCGCACTC
ACCCCGGACCGCCTCGACACCGTCTTCCGCCCCAAGGTCGACGCCATCACCCACCTCCAC
GACCTCACCCGCGACCAGGACCTGGCCGCGTTCGTGGTGTACTCGTCCGCCGCCGGAGTC
CTCGGCGGACCCGGCCAGGGCAACTACTCCGCCGCCAACGCCTATCTGGACGGCCTCGCA
CAGTGGCGGCGTGCGCACGGGCTCCCCGCCACCTCGCTGGCGTGGGGCATGTGGGCGCAG
ACCAGTGGCATGACGGCCGGGCTCGGCTCAGGGGATCTGCACCGGGTGCGGCGTGGCGGC
ATCGTCGGGCTGTCCACGGCGGAGGCGCTGGACCTGTTCGACCGGTCGGTGGCGTCCGGG
CTGTCCCTGCTGGTGCCGTTGCGGTTCGACCTCGCCGCCCTCGGTGCGGAGGCCGCGGAA
CCGCCGCCGCTGCTGCGGGGGCTGGTCCGGCCGGCCCGGCGTACGGCCCGGCCGGTGCCG
AAGGCCGGTGAGGGCGGCCTCGTCGAGCGGCTGGCCGGTCTTTCGGCGGCCGAACAGGAG
CGTCTGCTGGTCGAGTTGATCCGCGAACAGGCCGCTTCCGTGCTCGGGTTCCCGACCGTC
GACCCGATCGGGCCGGAGCAGGCATTCCGCGATATGGGGTTCGACTCGCTGACCGCGGTG
GAGCTGCGCAACCGCCTCAACACGGCCACCGGACTACGGCTCCCGGCGACGCTGGTCTTC
GACCACCCGACCCCCTTGGCCACCGCCGAGCTCCTACGGGACGAACTGGGCGGGCGCGCG
GTCGAGGCCACGCCCCGCCCGGCCCGGCGCGACCGGTCGGCTCCGGACGCGGCCGAGGAT
CCGGTCGTCGTGGTCGGCATGGGCTGCCGCCTGCCCGGCGACGTCCGCACCCCCGAGGAC
CTGTGGCGGCTGGTCGCCGCCGGAACCGACGCGATCGGGCCGTTCCCGCAGGACCGGGGC
TGGGACCTGGCCGGGCTCTTCGACTCCGACCCGGACGCCCTGGGCAAGTCCTACGTCCGC
GAGGGCGGCTTTCTCACCGACGCGGGCGGCTTCGACGCCACGTTCTTCGGCATCTCCCCG
CGCGAGGCCCTGTCGATGGACCCGCAGCAGCGTGTCCTGCTGGAGACCGCGTGGGAGACC
CTGGAACGCTCCGGGATCGTTCCCACGTCACTGCGCGGACAGGAGGTCGGGGTCTTCGTC
GGGGCCAGCGGCCAGGGGTACGGCACCGGTCCTGGCGCGGCTCCGGAAGGCTTGGAGGGC
TATCTGGGGGTGGGCGGCGCGACGAGTGTGGCGTCGGGCCGGTTGTCGTACACCTTCGGC
CTGACCGGTCCGGCGGTCACGGTGGACACGGCGTGCTCCTCCTCCCTGGTGGCCCTCCAC
CTCGCGGCACAAGCTCTGCGCTCCGGCGAATGCACGATGGCACTCGCGGGCGGTGTCGCG
GTGATGGGCCAGCCCGGCGCATTCGTCGAGTTCTCCCGCCAGCGCGGTCTCGCGTCCGAC
GGCCGCTGCAAGTCCTTCGGCGAGGGCGCCGACGGCACCAACTGGTCGGAGGGCGCGGGT
CTGGTGCTGCTGGAACGACTGTCCGACGCCCGCCGCAACGGCCATGAGGTGCTGGCCGTG
ATCCGTGGCACCGCGGTGAACCAGGACGGGGCGAGCAACGGCCTCACCGCTCCGAACGGG
CCCTCCCAGCAGCGAGTGATCCGGCAGGCCCTGTCCAATGCCGGGCTCACAGTGGCCGAC
GTGGACGCGGTCGAGGCACACGGCACCGGCACCGCCCTCGGCGACCCCATCGAGGCACAG
GCACTGCTCGCCACCTACGGCCAGGACCGCCCGGGGGACGAACCCGTGTGGCTCGGCTCG
CTGAAGTCCAACATCGGCCACACCCAAGCGGCCGCAGGCATATCCAGCGTCATCAAGATG
GTCCTGGCGATGCGGCAGGGCACGCTTCCCCGGTCCCTGCACGCCGACGAACCCACCACC
CAGGTGGACTGGACGTCGGGCGCGGTGTCCCTGCTGACCGAGGCACGGCCCTGGCCGGAG
ACCGGACACCTCCGCCGCGCCGGGATCTCCTCCTTCGGCGTCAGCGGGACAAACGCACAT
GTGGTCCTGGAGCAGGCCCCGGAAGCGGCCGCACCGCAGGCGGACGAGGCCGACGACATC
CCTGGTCTGGTCGCCACCGGCGGGATCGCGCCCTGGGTCCTGTCGGCCAAGACCCCCACG
GCCCTGCGGGCTCAGGCCCAACGCCTCCTGGACCACCTGGAATCCGGGGTGGACGGCCGC
CCCCTCGACATCGGCTGGTCCCTGGCCACCACCCGCACCCTCCACGACCATCGCGCCATA
ATCCTCACCGACACCGACACCGACACGCGCGCCGAGGGCGGTGAGGCCACGGCCGCCCTG
ACCGCCCTCGTGACCGGACAGCCGCATCCCCGCCTCACGACGGGCTACGCCACCACCCAG
GGCAAGACCGTGTTCGTTTTCCCGGGGCAGGGGTCGCAGTGGGTGGGGATGGGGGCACAG
CTCCTGGACACTTCGCCCGTCTTCGCGGCCCGGTTGCGCGAGTGTGCCGACGCGCTGGCC
CCGTATACCGACTGGTCCCTGATGGACGTCATCACCGGCGCACCCGATGCCCCTTCGCTC
GACCGTGTCGACGTCGTACAGCCCGCCACCTTCGCCGTCGTCGTCTCCCTCGCCACCCTC
TGGCAATCCATGGGTATCCACCCCGACGCCGTCACCGGCCACTCCCAAGGCGAAATCGCC
GCAGCCTGCGTCGCCGGACACCTCACCCTCACCAACGCCGCCAAAATCGTCGCCCTGCGC
AGCCAGATCATCGCCGACCACCTCGCCGGACACGGCGGCATGATGTCCCTCGCCACCCCC
GCCGACACCATCGACCTCACCAACTGGCACGGCAAACTCTGGATCGCCGCACACAACGGC
CCCAACGCCACCGTCATCGCAGGCGACGCCGAAGCCCTGCACCAACTCCACGCCCACTAC
ACCGACCAAGGCATCCGAGCCCGCATCATCCCCGTCGACTACGCCTCCCACACCGGACAC
GTCGACACCATCAAGAACGAACTCCACCAAACCCTGGCCGACACCACCACCGAGCCCGGC
ACCCTCCCCTGGCTCTCCACCGTCGACGGGGAGTGGATCGAACCCAACACCCTCGACAGC
ACCTACTGGTACCGCAATCTCCGCCAGACCGTGCAGTTCCACACCGCCATCACCACCCTC
GCCGACCAGGGCTACCGCACCTACATCGAAATCAGCCCCCACCCCGTCCTCACCACCGCC
ATCCAAGAAACCCTCGAAACACACAACACCCCCAACGCGATCGTCACCGGAACCCTCCGC
CGCGACGACGACACCCCCACCCGCCTCCTCACCAACCTCGCCCACCTCACCACCCACGGA
ACACCCGTCAACTGGCCCACCCTCTTCACCGGCACACACCCCACCCGCATCACCCTCCCC
ACCTACCCCTTCGAGCAGGAGACGTTCTGGCTGGACCGCAGCGGCCCGGGTGATGTCCGT
GCCGTCGGCCTGGAGGACACCGGCCATCCGCTGGTCGGGGCCGTGGTGAGTGTGCCCGAC
ACCGACGGTGTGCTGCTCACCGGGCGGCTCTCCCTGACCACCCACCCCTGGCTGGCCGAC
CATGCCGTCTCCGGCACCGTCTTGCTTCCCGGTACGGCGATGGTGGAGCTGGCGGTGCGA
GCCGGAGACGAGGCGGAGGCCCGCGTACTGGAGGAATTGATCATCAGTCGGCCGATGGCG
GTGCCGGACGAGGGAACCTTGCACGTCCAAGTGCTGGTCGGCGGCGAGGAAGGCGACGAA
GGCGGACGCCGCAAGGTGGGGGTCTACTCCCGCCCCGAGGGCATACGGCAGTGGACCGAG
CACGCCACCGGCACACTGCTGACCGGGGGAACCGCCACCGCGGCGGCCACGACAGCGCAT
CCGTGGCCGCCCGAGGGGGCCGAACCCGTCGCCCTCGAGGGGTTCTACGAGCAACTGGCC
GAGGCGGGGTACGAGTACGGCCCGGCGTTCCGGGGCCTGAGCGCGGTGTGGAAGCGGGAC
GACGAGGTGTTCGCCGAGGTGGCCGTGCCGGAGGACCAGACCGCGGTCGCCGGACGGTTC
GGCATCCATCCGGCGCTGCTGGACGCCACTCTGCATGCCGGGAACTTCTGCTTCGAGTCC
GGCGGCGACCGGCCCACGATGCTGCCGTTCGCCTGGACCGACGTGCGGCTCCATGCCGTG
GGCGCCACCGCTGTACGGGTGCGGGCGACGGCGTCCGGCACGGACGGGCTGTGTGTGCAG
ATCACCGATCCGCACGGACTGCCGGTCGCCACCATTGGCTCGCTCCAGCTCCGGGAGACC
ACACCCGAGCAGTTGCGGGCCCTCTCCGCCACCTCAGGTGGCAATGCCTTGTGGGCGGTC
GAATGGGCCGAATGCGGGCTCGACGACACGACGGAAGCACAGTGGGCCACACTCGGAGAG
AGCCAACTCCTGGACTCCCCACTTCACTATGCCGATGTTTCCCAGGTCGTGGCGGCCGGG
GAACAGCCCGCGGCACTCGTCGCCGACGTGTCCGCATGGGCTCCCGAGAACACCGGGCCG
CCCATCGACCGCGCCCACGCGCTCTGTGCCCGAGTCCTCGATCTGCTGCGGCAATGGGTG
GACCGGCCCGAGCCGGCGGACACCCGGCTGGTGATCCTGACCCGCGGTGCCATGGCGGTC
CACGACACCGCCGAGGTCACGGATGCGGCCGCCGCCGCGGTCTGGGGCCTGGTCCGCTCG
GCCCAGTCCGAACACCCGGGCCGGATCCAGCTCATCGACATCGACGAGCACTCCCACCGC
ACCCTGCCGACAGCACTCACCACCACCGACCAACCCCAACTCGCCCTCCGCGACGCCACC
GCCTACACCCCCCACCTGGCCCCCGCGCCCACCCCAACACCCGGGCCCCTCACCCTCGCG
CCCGAGGGAACCGTCCTCATCACCGGCGGCACCGGCACCCTCGGCGCCCTCACCGCCCGC
CACCTCATCACCCACCACAAGGCACGCAACCTCCTTCTGGTCAGCCGCCAGGGTCCGGAC
GCCCCCGGCGCGGACCGGCTGAGCGAGGAGCTGACCCAGCTCGGTGCCCGTATCCGCATC
GCCGCCTGCGATGTCGCCGACCGCGACCAGCTCGCCACCGTCCTCGCCACCATCCCCGCA
GACCAGCCGCTGACCGCCGTCATCCACACCGCCGGCGCCCTCGACGACGCCCTGCTCACC
GACCTCACCCCGGAACGCCTGGGCACCGTCTTCCGCCCCAAGGTCGACGCCCTCACCCAT
CTCCACGACCTCACCCGCGACCATGACCTCGCGGCCTTCGTCATCTACTCCTCCGCCACC
GGTGCGCTCGGCACCCCCGGTCAGGCCAACTACGCGGCGGCCAACACCTACGCCGACGCG
CTCGCCCAGCAGCGCCACGCCGCCGGGCTCCCCGCCACCTCACTCGCCTGGGGCCTGTGG
GAAACCACCAGCGCCCTCACGGCCGGGATGTCCACCACCCATCAGCAGCGCACCCGCCAC
AGCGGTGTCATTCCCCTGACCGACGCCGACGGCATGCGCCTCCTCGACACCGCGCTCACC
ACCCACCAGCCCCACCTGATCCCCCTCAAGCTCGATCGCACCGCCCTCCGGAACAGCGCC
GCCTCCCACACCCTCCCGCCCCTGCTCCGCACCCTGGCGCAAAGCCACCACCGCCCCACC
GCCCACACCACCCCCCGGACCGCCGCCGCCCCGCCCCTCCCCGAGCAACTCGCCGCCCTC
GATCCGGCCCAGCGGCTCCAGCACCTCACCGCATTCGTCCGCGCCGAAGCCGCGGCCGTG
CTCGGACACGCCACTTCGGACGCGGTGGGACCGGACGATCCGCTCTTCGAGATCGGGTTC
GACTCCCTGACCGCGGTGGAACTGCGCAACCGGCTCAACGCGGCCACGGGCCTCCAGCTC
CCGGCGGCGTTGCTGTTCGACCACCCCACCCCGGCGATGGCCGCCGAACACCTCCAGGAA
CAGCTCGCGCTGAAAGACGCCTCCTGA
[6] KS35..410
[6] AT584..907
[6] malonyl-CoA780..784
[6] DH954..1122
[6] ER1431..1731
[6] KR1741..1921
[6] ACP2023..2093
[7] KS2120..2495
[7] AT2664..2982
[7] methylmalonyl-CoA2854..2858
[7] DH3029..3193
[7] KR3503..3683
[7] ACP3789..3859
[6] KS103..1230
[6] AT1750..2721
[6] malonyl-CoA2338..2352
[6] DH2860..3366
[6] ER4291..5193
[6] KR5221..5763
[6] ACP6067..6279
[7] KS6358..7485
[7] AT7990..8946
[7] methylmalonyl-CoA8560..8574
[7] DH9085..9579
[7] KR10507..11049
[7] ACP11365..11577

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR001227 Acyl transferase domain (Domain)
[578-712] G3DSA:3.40.366.10 [780-894] G3DSA:3.40.366.10 [2656-2787] G3DSA:3.40.366.10 [2854-2972] G3DSA:3.40.366.10
G3DSA:3.40.366.10   Ac_transferase_reg
IPR002198 Short-chain dehydrogenase/reductase SDR (Family)
[1741-1908] 1.80000000000002e-63 PF00106
PF00106   adh_short
IPR006162 Phosphopantetheine attachment site (PTM)
[2051-2066] PS00012 [3817-3832] PS00012
PS00012   PHOSPHOPANTETHEINE
IPR009081 Acyl carrier protein-like (Domain)
[2026-2091] 4.2e-13 PF00550 [3793-3858] 1.3e-14 PF00550
PF00550   PP-binding
[2023-2093] PS50075 [3789-3859] PS50075
PS50075   ACP_DOMAIN
[2023-2097] 2.4e-44 G3DSA:1.10.1200.10 [3788-3862] 2.4e-44 G3DSA:1.10.1200.10
G3DSA:1.10.1200.10   ACP_like
[2016-2136] 1.10000150671642e-25 SSF47336 [3782-3862] 7.00000734129907e-23 SSF47336
SSF47336   ACP_like
IPR011032 GroES-like (Domain)
[1425-1576] 4.90001027782408e-33 SSF50129
SSF50129   GroES_like
IPR013154 Alcohol dehydrogenase GroES-like (Domain)
[1451-1506] 1e-08 PF08240
PF08240   ADH_N
IPR013968 Polyketide synthase, KR (Domain)
[3503-3682] 3.40000000000004e-60 PF08659
PF08659   KR
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
[35-285] 6.29999999999998e-92 PF00109 [2120-2370] 3.60000000000002e-92 PF00109
PF00109   ketoacyl-synt
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
[293-410] 2.1e-47 PF02801 [2378-2495] 1.40000000000001e-47 PF02801
PF02801   Ketoacyl-synt_C
IPR014043 Acyl transferase (Domain)
[584-907] 1.29999999999998e-64 PF00698 [2664-2982] 8.19999999999987e-103 PF00698
PF00698   Acyl_transf_1
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
[580-890] 3.89999861795218e-73 SSF52151 [2662-2952] 3.49999466863949e-67 SSF52151
SSF52151   Acyl_Trfase/lysoPlipase
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
[714-779] 2.800005042611e-17 SSF55048 [2790-2853] 5.09999882439978e-15 SSF55048
SSF55048   Malonyl_transacylase_ACP-bd
IPR016038 Thiolase-like, subgroup (Domain)
[37-297] G3DSA:3.40.47.10 [298-465] 1.39999999999997e-127 G3DSA:3.40.47.10 [2122-2382] G3DSA:3.40.47.10 [2383-2548] 1.39999999999997e-127 G3DSA:3.40.47.10
G3DSA:3.40.47.10   Thiolase-like_subgr
IPR016039 Thiolase-like (Domain)
[27-463] 1.79999754022378e-100 SSF53901 [2112-2548] 4.10001399699315e-101 SSF53901
SSF53901   Thiolase-like
IPR016040 NAD(P)-binding domain (Domain)
[1521-1706] 6.19999999999995e-47 G3DSA:3.40.50.720 [1741-1928] 1e-72 G3DSA:3.40.50.720 [3503-3709] 2.39999999999997e-69 G3DSA:3.40.50.720
G3DSA:3.40.50.720   NAD(P)-bd
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
[2283-2299] PS00606
PS00606   B_KETOACYL_SYNTHASE
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
[584-887] 1.59998835313644e-129 SM00827 [2666-2963] 5.39997012872478e-119 SM00827
SM00827   PKS_AT
IPR020806 Polyketide synthase, phosphopantetheine-binding domain (Domain)
[2024-2096] 9.10000425645573e-34 SM00823 [3790-3862] 1.10000150671643e-34 SM00823
SM00823   PKS_PP
IPR020807 Polyketide synthase, dehydratase domain (Domain)
[954-1122] 9.40003071030835e-77 SM00826 [3029-3193] 2.39999798157263e-79 SM00826
SM00826   PKS_DH
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain (Domain)
[37-463] SM00825 [2122-2548] SM00825
SM00825   PKS_KS
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
[1741-1921] 1.49999648196323e-59 SM00822 [3503-3683] 4.19999771339582e-60 SM00822
SM00822   PKS_KR
IPR020843 Polyketide synthase, enoylreductase (Domain)
[1431-1731] SM00829
SM00829   PKS_ER
SignalP No significant hit
TMHMM No significant hit
Herb_00180 Herb_00180   Herb_00200 Herb_00200
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