BLAST table : Herb_00190

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q49BD9_STRHY
(Q49BD9)		 
[query] 1 - 3868 (3868)
[subject] 1 - 3868 (3868)
 0.0 7643   100% HbmAIII hbmAIII Streptomyces hygroscopicus
2
 E0KLD7_STRVO
(E0KLD7)		 
[query] 1 - 3868 (3868)
[subject] 1 - 3867 (3867)
 0.0 6977   94% (Acyl-carrier-protein) S-malonyltransferase., 6-deoxyerythronolide-B synthase StrviDRAFT_3410 Streptomyces violaceusniger Tu 4113 2.3.1.39

2.3.1.94
3
 Q1L0T0_STRHY
(Q1L0T0)		 
[query] 1 - 3868 (3868)
[subject] 1 - 3868 (3888)
 0.0 6735   90% GelC Streptomyces hygroscopicus subsp. duamyceticus
4
 Q84G22_STRHY
(Q84G22)		 Jump to Gelda2_00100 
[query] 1 - 3868 (3868)
[subject] 1 - 3876 (3896)
 0.0 6734   90% GdmAIII gdmAIII Streptomyces hygroscopicus
5
 F1CT53_9ACTO
(F1CT53)		 
[query] 1 - 3864 (3868)
[subject] 1 - 3850 (3872)
(2 hsp)		 0.0 6509   88% GdmAIII gdmAIII Streptomyces autolyticus
6
 Q06BM4_STRHY
(Q06BM4)		 Jump to Gelda_00010 
[query] 820 - 3864 (3868)
[subject] 1 - 3031 (3053)
(3 hsp)		 0.0 5096   87% GdmPKS gdmPKS Streptomyces hygroscopicus
7
 B5A9Q1_9PSEU
(B5A9Q1)		 
[query] 4 - 3863 (3868)
[subject] 12 - 3833 (3874)
 0.0 4269   63% MbcAIII mbcAIII Actinosynnema pretiosum subsp. pretiosum
8
 C6W8U9_ACTMD
(C6W8U9)		 
[query] 4 - 3863 (3868)
[subject] 12 - 3833 (3874)
 0.0 4234   63% Short-chain dehydrogenase/reductase SDR Amir_3292 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
9
 Q1L0T2_STRHY
(Q1L0T2)		 
[query] 33 - 3489 (3868)
[subject] 1115 - 4545 (6855)
(9 hsp)		 0.0 3982   63% GelA Streptomyces hygroscopicus subsp. duamyceticus
10
 Q49BE1_STRHY
(Q49BE1)		 Jump to Herb_00170 
[query] 33 - 3489 (3868)
[subject] 1086 - 4515 (6820)
(9 hsp)		 0.0 3977   63% HbmAI hbmAI Streptomyces hygroscopicus
11
 Q84G24_STRHY
(Q84G24)		 Jump to Gelda2_00080 
[query] 33 - 3489 (3868)
[subject] 1101 - 4532 (6842)
(9 hsp)		 0.0 3971   63% GdmAI gdmAI Streptomyces hygroscopicus
12
 F1CT51_9ACTO
(F1CT51)		 
[query] 33 - 3486 (3868)
[subject] 1119 - 4528 (6840)
(9 hsp)		 0.0 3935   62% GdmAI gdmAI Streptomyces autolyticus
13
 Q0R4M3_STRAT
(Q0R4M3)		 Jump to Chth_00310 
[query] 4 - 3863 (3868)
[subject] 2 - 3862 (3936)
 0.0 3454   51% ChlA5 Streptomyces antibioticus
14
 Q52V50_9ACTO
(Q52V50)		 
[query] 29 - 3862 (3868)
[subject] 1828 - 5661 (7510)
(7 hsp)		 0.0 3448   53% Polyketide synthase type I Streptomyces aizunensis
15
 C6W8V1_ACTMD
(C6W8V1)		 
[query] 2 - 3489 (3868)
[subject] 1074 - 4497 (6768)
(9 hsp)		 0.0 3363   57% Acyl transferase Amir_3294 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
16
 B5A9P9_9PSEU
(B5A9P9)		 
[query] 2 - 3489 (3868)
[subject] 1087 - 4504 (6775)
(9 hsp)		 0.0 3363   57% MbcAI mbcAI Actinosynnema pretiosum subsp. pretiosum
17
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 35 - 3862 (3868)
[subject] 1767 - 5486 (7488)
(8 hsp)		 0.0 3332   52% ObsC Saccharopolyspora spinosa
18
 D7C2B8_STRBB
(D7C2B8)		 
[query] 39 - 3867 (3868)
[subject] 1581 - 5365 (7498)
(8 hsp)		 0.0 3292   51% Type I modular polyketide synthase pks3-2
SBI_00651		 Streptomyces bingchenggensis (strain BCW-1)
19
 C0Z473_STRVN
(C0Z473)		 
[query] 20 - 3868 (3868)
[subject] 2 - 3865 (3973)
 0.0 3286   52% Type I polyketide synthase, modules 4-5 ken12 Streptomyces violaceoruber
20
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 35 - 3862 (3868)
[subject] 3501 - 7297 (10917)
(10 hsp)		 0.0 3261   51% AmphC amphC Streptomyces nodosus
21
 A4FH83_SACEN
(A4FH83)		 
[query] 3 - 3862 (3868)
[subject] 2 - 3759 (5359)
(5 hsp)		 0.0 3258   50% Type I modular polyketide synthase SACE_4139 Saccharopolyspora erythraea (strain NRRL 23338)
22
 Q5VKR4_SACER
(Q5VKR4)		 
[query] 3 - 3862 (3868)
[subject] 2 - 3759 (5359)
(5 hsp)		 0.0 3258   50% Type I PKS pkeAIII Saccharopolyspora erythraea
Streptomyces erythraeus
23
 A1YAM7_AMYOR
(A1YAM7)		 
[query] 35 - 3493 (3868)
[subject] 1657 - 4954 (5723)
(7 hsp)		 0.0 3223   54% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
24
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 35 - 3868 (3868)
[subject] 137 - 3953 (5826)
(5 hsp)		 0.0 3207   50% Polyketide synthase modules 1-3 vinP1 Streptomyces halstedii
25
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 30 - 3858 (3868)
[subject] 2062 - 5760 (7576)
(8 hsp)		 0.0 3201   50% Type I modular polyketide synthase ttnB Streptomyces griseochromogenes
26
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 30 - 3858 (3868)
[subject] 2104 - 5806 (7620)
(8 hsp)		 0.0 3196   50% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
27
 E0KRC7_STRVO
(E0KRC7)		 
[query] 35 - 3863 (3868)
[subject] 1731 - 5479 (5559)
(6 hsp)		 0.0 3188   50% Beta-ketoacyl synthase StrviDRAFT_5204 Streptomyces violaceusniger Tu 4113
28
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 35 - 3862 (3868)
[subject] 3277 - 7021 (7102)
(7 hsp)		 0.0 3184   50% Polyketide synthase merB Streptomyces sp. NRRL 30748
29
 D7F1M1_9ACTO
(D7F1M1)		 
[query] 4 - 3862 (3868)
[subject] 3 - 3816 (5630)
(4 hsp)		 0.0 3158   48% Polyketide synthase tsnAIII Streptomyces longisporoflavus
30
 E0L075_STRVO
(E0L075)		 
[query] 35 - 3381 (3868)
[subject] 1801 - 5136 (5786)
(9 hsp)		 0.0 3156   54% Beta-ketoacyl synthase StrviDRAFT_8303 Streptomyces violaceusniger Tu 4113
31
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 3 - 3862 (3868)
[subject] 2 - 3874 (5718)
(3 hsp)		 0.0 3156   49% ChlA3 Streptomyces antibioticus
32
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 35 - 3862 (3868)
[subject] 3322 - 7097 (7178)
(7 hsp)		 0.0 3150   49% MerB merB Streptomyces violaceoniger
33
 D7F1M2_9ACTO
(D7F1M2)		 
[query] 35 - 3862 (3868)
[subject] 2139 - 5941 (6036)
(4 hsp)		 0.0 3133   48% Polyketide synthase tsnAIV Streptomyces longisporoflavus
34
 Q54297_STRHY
(Q54297)		 Jump to Rapam_00120 
[query] 35 - 3863 (3868)
[subject] 4881 - 8488 (8563)
(6 hsp)		 0.0 3117   49% Polyketide synthase rapA Streptomyces hygroscopicus
35
 B5L6M3_MICCH
(B5L6M3)		 
[query] 3 - 3862 (3868)
[subject] 12 - 3873 (3953)
(2 hsp)		 0.0 3101   48% Putative type I polyketide synthase Micromonospora chalcea
36
 Q93NX8_9ACTO
(Q93NX8)		 Jump to Amph_00050 
[query] 35 - 3868 (3868)
[subject] 1798 - 5565 (5644)
(4 hsp)		 0.0 3095   49% AmphJ amphJ Streptomyces nodosus
37
 E8S0C6_MICSL
(E8S0C6)		 
[query] 3 - 3455 (3868)
[subject] 2 - 3423 (7520)
(8 hsp)		 0.0 3056   53% Beta-ketoacyl synthase ML5_5899 Micromonospora sp. (strain L5)
38
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 35 - 3862 (3868)
[subject] 3524 - 7296 (10876)
(12 hsp)		 0.0 3054   51% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
39
 D9T6W3_MICAI
(D9T6W3)		 
[query] 3 - 3455 (3868)
[subject] 2 - 3423 (7520)
(8 hsp)		 0.0 3047   53% Acyl transferase Micau_2463 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
40
 Q6W5P9_9ACTO
(Q6W5P9)		 Jump to FR008_00170 
[query] 8 - 3862 (3868)
[subject] 1570 - 5460 (5541)
(7 hsp)		 0.0 3037   49% FscB fscB Streptomyces sp. FR-008
41
 E0L2P8_STRVO
(E0L2P8)		 
[query] 31 - 2714 (3868)
[subject] 1178 - 3834 (3834)
(4 hsp)		 0.0 3028   62% Beta-ketoacyl synthase StrviDRAFT_9176 Streptomyces violaceusniger Tu 4113
42
 B3TMP1_9ACTO
(B3TMP1)		 
[query] 3 - 3868 (3868)
[subject] 12 - 3852 (3921)
 0.0 3016   49% Polyketide synthase KijS4 Actinomadura kijaniata
43
 Q1MX73_9ACTO
(Q1MX73)		 Jump to Tetrn_00160 
[query] 4 - 3862 (3868)
[subject] 3 - 3842 (5657)
(5 hsp)		 0.0 2997   48% Type I polyketide synthase tmnAIV Streptomyces sp. NRRL 11266
44
 Q1MX72_9ACTO
(Q1MX72)		 Jump to Tetrn_00170 
[query] 35 - 3862 (3868)
[subject] 2102 - 5873 (5963)
(5 hsp)		 0.0 2989   48% Type I polyketide synthase tmnAV Streptomyces sp. NRRL 11266
45
 F8K324_STRCT
(F8K324)		 
[query] 4 - 3863 (3868)
[subject] 3 - 3850 (3931)
(2 hsp)		 0.0 2982   47% Polyketide synthase type I (Modular protein) SCAT_0140 Streptomyces cattleya
46
 D0LQW2_HALO1
(D0LQW2)		 
[query] 9 - 3867 (3868)
[subject] 1 - 3850 (3930)
 0.0 2956   46% KR domain protein Hoch_2956 Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)
47
 A8J704_9ACTO
(A8J704)		 
[query] 1 - 3868 (3868)
[subject] 1 - 3848 (5674)
(3 hsp)		 0.0 2929   47% Modular polyketide synthase nemA3 Streptomyces cyaneogriseus subsp. noncyanogenus
48
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 35 - 3860 (3868)
[subject] 3266 - 6849 (10223)
(11 hsp)		 0.0 2896   47% Polyketide synthase rapB Streptomyces hygroscopicus
49
 C0SMW2_9ACTO
(C0SMW2)		 Jump to Tauto_00090 
[query] 29 - 3849 (3868)
[subject] 1749 - 5460 (5770)
(4 hsp)		 0.0 2894   47% Type I modular polyketide synthase ttmH Streptomyces spiroverticillatus
50
 E3JBU2_FRASU
(E3JBU2)		 
[query] 18 - 3863 (3868)
[subject] 1798 - 5826 (7679)
(7 hsp)		 0.0 2884   47% Acyl transferase FraEuI1c_4253 Frankia sp. (strain EuI1c)
51
 Q93HJ3_STRAW
(Q93HJ3)		 Jump to Oligo_00100 
[query] 3 - 3867 (3868)
[subject] 2 - 3865 (3939)
(2 hsp)		 0.0 2880   47% Modular polyketide synthase olmA3
SAV2897
SAV_2897		 Streptomyces avermitilis
52
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 35 - 3868 (3868)
[subject] 7422 - 11212 (11604)
(17 hsp)		 0.0 2880   46% MerC merC Streptomyces violaceoniger
53
 E0KRC6_STRVO
(E0KRC6)		 
[query] 35 - 3868 (3868)
[subject] 7379 - 11071 (11118)
(19 hsp)		 0.0 2870   47% Beta-ketoacyl synthase StrviDRAFT_5203 Streptomyces violaceusniger Tu 4113
54
 Q9ADL6_SORCE
(Q9ADL6)		 Jump to Soraph_00070 
[query] 31 - 3489 (3868)
[subject] 2089 - 5539 (6315)
(10 hsp)		 0.0 2867   49% Soraphen polyketide synthase A sorA Sorangium cellulosum
Polyangium cellulosum
55
 Q6W5P7_9ACTO
(Q6W5P7)		 Jump to FR008_00190 
[query] 1 - 3456 (3868)
[subject] 1 - 3370 (7771)
(8 hsp)		 0.0 2845   51% FscE fscE Streptomyces sp. FR-008
56
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 35 - 3862 (3868)
[subject] 3622 - 7528 (16990)
(14 hsp)		 0.0 2843   45% Type I modular polyketide synthase mlsA1
MUP040c		 Mycobacterium ulcerans (strain Agy99)
57
 D6B4R4_9ACTO
(D6B4R4)		 
[query] 1 - 3298 (3868)
[subject] 171 - 3390 (3428)
(3 hsp)		 0.0 2804   52% Polyketide synthase SSHG_00095 Streptomyces albus J1074
58
 D9WAY3_9ACTO
(D9WAY3)		 
[query] 153 - 3486 (3868)
[subject] 1 - 3322 (4394)
(4 hsp)		 0.0 2781   50% Polyketide synthase SSOG_00489 Streptomyces himastatinicus ATCC 53653
59
 B6ZK65_STRLS
(B6ZK65)		 Jump to Lasal_00140 
[query] 31 - 3012 (3868)
[subject] 1746 - 4685 (5429)
(8 hsp)		 0.0 2726   53% Putative polyketide synthase lsd12 Streptomyces lasaliensis
60
 B5M9K9_STRLS
(B5M9K9)		 Jump to Lasal2_00170 
[query] 31 - 3012 (3868)
[subject] 1786 - 4725 (5469)
(8 hsp)		 0.0 2726   53% Lasalocid modular polyketide synthase lasAII Streptomyces lasaliensis
61
 B2HF44_MYCMM
(B2HF44)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3401 (4187)
(4 hsp)		 0.0 2721   47% Polyketide synthase, Pks12 pks12
MMAR_3025		 Mycobacterium marinum (strain ATCC BAA-535 / M)
62
 A0PQM7_MYCUA
(A0PQM7)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3405 (4191)
(4 hsp)		 0.0 2720   47% Polyketide synthase, Pks12 pks12
MUL_2266		 Mycobacterium ulcerans (strain Agy99)
63
 Q7VES2_MYCBO
(Q7VES2)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2705   47% Probable polyketide synthase pks12 pks12
Mb2074c		 Mycobacterium bovis
64
 D9W5N6_9ACTO
(D9W5N6)		 
[query] 1 - 3018 (3868)
[subject] 1 - 3033 (3116)
(3 hsp)		 0.0 2704   52% Modular polyketide synthase SSNG_07466 Streptomyces sp. C
65
 D7CC08_STRBB
(D7CC08)		 
[query] 35 - 3012 (3868)
[subject] 1812 - 4775 (5530)
(8 hsp)		 0.0 2696   52% Putative type I polyketide synthase pks5-2
SBI_01382		 Streptomyces bingchenggensis (strain BCW-1)
66
 C1APW8_MYCBT
(C1APW8)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2692   47% Putative polyketide synthase pks12
JTY_2062		 Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)
67
 A5WP27_MYCTF
(A5WP27)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2692   47% Putative uncharacterized protein TBFG_12085 Mycobacterium tuberculosis (strain F11)
68
 A1KK94_MYCBP
(A1KK94)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2692   47% Probable polyketide synthase pks12 pks12
BCG_2067c		 Mycobacterium bovis (strain BCG / Pasteur 1173P2)
69
 Q7D7J7_MYCTU
(Q7D7J7)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2691   47% Polyketide synthase MT2108 Mycobacterium tuberculosis
70
 C6DQ18_MYCTK
(C6DQ18)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3367 (4152)
(4 hsp)		 0.0 2690   47% Putative uncharacterized protein TBMG_01933 Mycobacterium tuberculosis (strain KZN 1435 / MDR)
71
 F8LZU0_9MYCO
(F8LZU0)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2690   47% Putative polyketide synthase pks12 pks12
MAF_20630		 Mycobacterium africanum GM041182
72
 F2GDY9_MYCTU
(F2GDY9)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3367 (4152)
(4 hsp)		 0.0 2690   47% Polyketide synthase pks12 TBSG_01946 Mycobacterium tuberculosis KZN 4207
73
 D6FVS6_MYCTU
(D6FVS6)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2690   47% Polyketide synthase pks12 TBOG_02571 Mycobacterium tuberculosis K85
74
 A2VJF6_MYCTU
(A2VJF6)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2690   47% Putative uncharacterized protein TBCG_02001 Mycobacterium tuberculosis C
75
 A0ACH2_STRAM
(A0ACH2)		 
[query] 21 - 3012 (3868)
[subject] 26 - 2940 (3661)
(6 hsp)		 0.0 2689   53% Putative polyketide synthase B SAMR0466 Streptomyces ambofaciens ATCC 23877
76
 D7ESD7_MYCTU
(D7ESD7)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2687   47% Polyketide synthase TBAG_00970 Mycobacterium tuberculosis 94_M4241A
77
 O53490_MYCTU
(O53490)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2686   47% Probable polyketide synthase pks12 pks12
Rv2048c		 Mycobacterium tuberculosis
78
 A5U473_MYCTA
(A5U473)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2685   47% Polyketide synthase Pks12 pks12
MRA_2063		 Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
79
 Q73Z07_MYCPA
(Q73Z07)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3384 (4170)
(4 hsp)		 0.0 2665   47% Pks12 pks12
MAP_1796c		 Mycobacterium paratuberculosis
80
 A0QFF5_MYCA1
(A0QFF5)		 
[query] 10 - 3483 (3868)
[subject] 11 - 3385 (4171)
(4 hsp)		 0.0 2662   47% Erythronolide synthase, modules 3 and 4 MAV_2450 Mycobacterium avium (strain 104) 2.3.1.94
81
 B1W5P3_STRGG
(B1W5P3)		 
[query] 3 - 3862 (3868)
[subject] 2 - 3440 (3522)
(3 hsp)		 0.0 2659   44% Putative type-I PKS pks3-3
SGR_6371		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
82
 C0SMW3_9ACTO
(C0SMW3)		 Jump to Tauto_00100 
[query] 1 - 3012 (3868)
[subject] 1 - 2953 (5710)
(7 hsp)		 0.0 2655   52% Type I modular polyketide synthase ttmI Streptomyces spiroverticillatus
83
 B5M9L2_STRLS
(B5M9L2)		 Jump to Lasal2_00200 
[query] 1 - 3026 (3868)
[subject] 1 - 3002 (3679)
(5 hsp)		 0.0 2653   52% Lasalocid modular polyketide synthase
Putative polyketide synthase		 lasAV
lsd15		 Streptomyces lasaliensis
84
 Q0ILD2_9ACTO
(Q0ILD2)		 
[query] 288 - 3868 (3868)
[subject] 193 - 3758 (3835)
(2 hsp)		 0.0 2648   47% NlmA3 nlmA3 Streptomyces nanchangensis
85
 A0ACI3_STRAM
(A0ACI3)		 
[query] 3 - 3010 (3868)
[subject] 2 - 2941 (5447)
(8 hsp)		 0.0 2647   52% Putative type I modular polyketide synthase SAMR0477 Streptomyces ambofaciens ATCC 23877
86
 D7C2B7_STRBB
(D7C2B7)		 
[query] 8 - 2621 (3868)
[subject] 7 - 2583 (2716)
(3 hsp)		 0.0 2640   56% Type I modular polyketide synthase pks3-1
SBI_00650		 Streptomyces bingchenggensis (strain BCW-1)
87
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 29 - 3012 (3868)
[subject] 7193 - 10160 (10827)
(15 hsp)		 0.0 2607   51% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
88
 C6K7D8_9ACTO
(C6K7D8)		 
[query] 35 - 3862 (3868)
[subject] 1217 - 4686 (7938)
(7 hsp)		 0.0 2606   45% Polyketide synthase rapA Actinoplanes sp. N902-109
89
 Q9L4X2_9ACTO
(Q9L4X2)		 Jump to Nysta_00060 
[query] 6 - 3010 (3868)
[subject] 12 - 2978 (5435)
(8 hsp)		 0.0 2596   52% NysJ nysJ Streptomyces noursei
90
 Q9KID7_STRHY
(Q9KID7)		 Jump to Asco_00170 
[query] 5 - 3862 (3868)
[subject] 4 - 3425 (6396)
(7 hsp)		 0.0 2595   45% FkbA fkbA Streptomyces hygroscopicus subsp. ascomyceticus
91
 E0D203_9ACTO
(E0D203)		 Jump to FD891_00020 
[query] 4 - 3012 (3868)
[subject] 27 - 3065 (5571)
(7 hsp)		 0.0 2581   51% Polyketide synthase gfsB Streptomyces graminofaciens
92
 A4FDM8_SACEN
(A4FDM8)		 
[query] 10 - 3018 (3868)
[subject] 1042 - 4016 (4132)
(7 hsp)		 0.0 2545   51% Modular polyketide synthase- SACE_2875 Saccharopolyspora erythraea (strain NRRL 23338)
93
 C0Z475_STRVN
(C0Z475)		 
[query] 1 - 3019 (3868)
[subject] 1 - 3015 (3447)
(5 hsp)		 0.0 2539   51% Type I polyketide synthase, modules 7-8 ken14 Streptomyces violaceoruber
94
 D2CKL6_PSEAH
(D2CKL6)		 
[query] 6 - 3010 (3868)
[subject] 13 - 2969 (5425)
(7 hsp)		 0.0 2524   51% CppJ cppJ Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
95
 E9KTB8_STRKN
(E9KTB8)		 
[query] 5 - 3862 (3868)
[subject] 4 - 3453 (6408)
(7 hsp)		 0.0 2522   44% Polyketide synthase fkbA
Tcs_SK_034		 Streptomyces kanamyceticus
96
 C6W8K9_ACTMD
(C6W8K9)		 
[query] 28 - 3862 (3868)
[subject] 980 - 4535 (4575)
(3 hsp)		 0.0 2504   46% Acyl transferase Amir_3197 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
97
 E9KTI5_9ACTO
(E9KTI5)		 
[query] 5 - 3867 (3868)
[subject] 4 - 3455 (6418)
(6 hsp)		 0.0 2483   44% Polyketide synthase fkbA
Tcs_11604BP_031		 Streptomyces sp. KCTC 11604BP
98
 B2HNF5_MYCMM
(B2HNF5)		 
[query] 4 - 3011 (3868)
[subject] 3 - 2991 (5495)
(7 hsp)		 0.0 2477   48% Type I modular polyketide synthase MMAR_3798 Mycobacterium marinum (strain ATCC BAA-535 / M)
99
 F1D8Z9_9ACTO
(F1D8Z9)		 
[query] 5 - 3867 (3868)
[subject] 4 - 3455 (6418)
(6 hsp)		 0.0 2472   44% FkbA Streptomyces sp. MJM7001
100
 P95814_STRSQ
(P95814)		 
[query] 5 - 3862 (3868)
[subject] 4 - 3466 (6420)
(8 hsp)		 0.0 2468   43% FK506 polyketide synthase fkbA Streptomyces sp
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q49BD9_STRHY
(Q49BD9)		 
[query] 1 - 3868 (3868)
[subject] 1 - 3868 (3868)
 0.0 7643   100%
Product
HbmAIII
Gene
hbmAIII
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 16085885
Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005]
3
 Q1L0T0_STRHY
(Q1L0T0)		 
[query] 1 - 3868 (3868)
[subject] 1 - 3868 (3888)
 0.0 6735   90%
Product
GelC
Gene
 
Organism
Streptomyces hygroscopicus subsp. duamyceticus
1uniprot[Pubmed] 18600054
Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008]
4
 Q84G22_STRHY
(Q84G22)		 Jump to Gelda2_00100 
[query] 1 - 3868 (3868)
[subject] 1 - 3876 (3896)
 0.0 6734   90%
Product
GdmAIII
Gene
gdmAIII
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 12586396 [Medline] 22474162
Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003]
5
 F1CT53_9ACTO
(F1CT53)		 
[query] 1 - 3864 (3868)
[subject] 1 - 3850 (3872)
(2 hsp)		 0.0 6509   88%
Product
GdmAIII
Gene
gdmAIII
Organism
Streptomyces autolyticus
1uniprot[Pubmed] 21544574
Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011]
6
 Q06BM4_STRHY
(Q06BM4)		 Jump to Gelda_00010 
[query] 820 - 3864 (3868)
[subject] 1 - 3031 (3053)
(3 hsp)		 0.0 5096   87%
Product
GdmPKS
Gene
gdmPKS
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 18214443
The LuxR family members GdmRI and GdmRII are positive regulators of geldanamycin biosynthesis in Streptomyces hygroscopicus 17997.(Arch. Microbiol.) [2008]
8
 C6W8U9_ACTMD
(C6W8U9)		 
[query] 4 - 3863 (3868)
[subject] 12 - 3833 (3874)
 0.0 4234   63%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_3292
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
9
 Q1L0T2_STRHY
(Q1L0T2)		 
[query] 33 - 3489 (3868)
[subject] 1115 - 4545 (6855)
(9 hsp)		 0.0 3982   63%
Product
GelA
Gene
 
Organism
Streptomyces hygroscopicus subsp. duamyceticus
1uniprot[Pubmed] 18600054
Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427.(J. Microbiol. Biotechnol.) [2008]
10
 Q49BE1_STRHY
(Q49BE1)		 Jump to Herb_00170 
[query] 33 - 3489 (3868)
[subject] 1086 - 4515 (6820)
(9 hsp)		 0.0 3977   63%
Product
HbmAI
Gene
hbmAI
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 16085885
Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.(Appl. Environ. Microbiol.) [2005]
11
 Q84G24_STRHY
(Q84G24)		 Jump to Gelda2_00080 
[query] 33 - 3489 (3868)
[subject] 1101 - 4532 (6842)
(9 hsp)		 0.0 3971   63%
Product
GdmAI
Gene
gdmAI
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 12586396 [Medline] 22474162
Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602.(FEMS Microbiol. Lett.) [2003]
12
 F1CT51_9ACTO
(F1CT51)		 
[query] 33 - 3486 (3868)
[subject] 1119 - 4528 (6840)
(9 hsp)		 0.0 3935   62%
Product
GdmAI
Gene
gdmAI
Organism
Streptomyces autolyticus
1uniprot[Pubmed] 21544574
Streptomyces autolyticus JX-47 Large-Insert Bacterial Artificial Chromosome Library Construction and Identification of Clones Covering Geldanamycin Biosynthesis Gene Cluster.(Curr. Microbiol.) [2011]
13
 Q0R4M3_STRAT
(Q0R4M3)		 Jump to Chth_00310 
[query] 4 - 3863 (3868)
[subject] 2 - 3862 (3936)
 0.0 3454   51%
Product
ChlA5
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
14
 Q52V50_9ACTO
(Q52V50)		 
[query] 29 - 3862 (3868)
[subject] 1828 - 5661 (7510)
(7 hsp)		 0.0 3448   53%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
15
 C6W8V1_ACTMD
(C6W8V1)		 
[query] 2 - 3489 (3868)
[subject] 1074 - 4497 (6768)
(9 hsp)		 0.0 3363   57%
Product
Acyl transferase
Gene
Amir_3294
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
17
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 35 - 3862 (3868)
[subject] 1767 - 5486 (7488)
(8 hsp)		 0.0 3332   52%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
18
 D7C2B8_STRBB
(D7C2B8)		 
[query] 39 - 3867 (3868)
[subject] 1581 - 5365 (7498)
(8 hsp)		 0.0 3292   51%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
20
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 35 - 3862 (3868)
[subject] 3501 - 7297 (10917)
(10 hsp)		 0.0 3261   51%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
21
 A4FH83_SACEN
(A4FH83)		 
[query] 3 - 3862 (3868)
[subject] 2 - 3759 (5359)
(5 hsp)		 0.0 3258   50%
Product
Type I modular polyketide synthase
Gene
SACE_4139
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
22
 Q5VKR4_SACER
(Q5VKR4)		 
[query] 3 - 3862 (3868)
[subject] 2 - 3759 (5359)
(5 hsp)		 0.0 3258   50%
Product
Type I PKS
Gene
pkeAIII
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15925898
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004]
23
 A1YAM7_AMYOR
(A1YAM7)		 
[query] 35 - 3493 (3868)
[subject] 1657 - 4954 (5723)
(7 hsp)		 0.0 3223   54%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
24
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 35 - 3868 (3868)
[subject] 137 - 3953 (5826)
(5 hsp)		 0.0 3207   50%
Product
Polyketide synthase modules 1-3
Gene
vinP1
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
25
 C6ZCS0_9ACTO
(C6ZCS0)		 
[query] 30 - 3858 (3868)
[subject] 2062 - 5760 (7576)
(8 hsp)		 0.0 3201   50%
Product
Type I modular polyketide synthase
Gene
ttnB
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
26
 A4KCE5_9ACTO
(A4KCE5)		 Jump to Tatmc_00090 
[query] 30 - 3858 (3868)
[subject] 2104 - 5806 (7620)
(8 hsp)		 0.0 3196   50%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
2uniprot[Pubmed] 20623733
Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase.(Angew. Chem. Int. Ed.) [2010]
[pubmed all]
28
 Q1WEK8_9ACTO
(Q1WEK8)		 
[query] 35 - 3862 (3868)
[subject] 3277 - 7021 (7102)
(7 hsp)		 0.0 3184   50%
Product
Polyketide synthase
Gene
merB
Organism
Streptomyces sp. NRRL 30748
1uniprot[Pubmed] 16806745
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748.(Gene) [2006]
31
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 3 - 3862 (3868)
[subject] 2 - 3874 (5718)
(3 hsp)		 0.0 3156   49%
Product
ChlA3
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
32
 A0FCL2_STRVO
(A0FCL2)		 Jump to Merid_00030 
[query] 35 - 3862 (3868)
[subject] 3322 - 7097 (7178)
(7 hsp)		 0.0 3150   49%
Product
MerB
Gene
merB
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
34
 Q54297_STRHY
(Q54297)		 Jump to Rapam_00120 
[query] 35 - 3863 (3868)
[subject] 4881 - 8488 (8563)
(6 hsp)		 0.0 3117   49%
Product
Polyketide synthase
Gene
rapA
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
35
 B5L6M3_MICCH
(B5L6M3)		 
[query] 3 - 3862 (3868)
[subject] 12 - 3873 (3953)
(2 hsp)		 0.0 3101   48%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
36
 Q93NX8_9ACTO
(Q93NX8)		 Jump to Amph_00050 
[query] 35 - 3868 (3868)
[subject] 1798 - 5565 (5644)
(4 hsp)		 0.0 3095   49%
Product
AmphJ
Gene
amphJ
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
38
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 35 - 3862 (3868)
[subject] 3524 - 7296 (10876)
(12 hsp)		 0.0 3054   51%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
40
 Q6W5P9_9ACTO
(Q6W5P9)		 Jump to FR008_00170 
[query] 8 - 3862 (3868)
[subject] 1570 - 5460 (5541)
(7 hsp)		 0.0 3037   49%
Product
FscB
Gene
fscB
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
42
 B3TMP1_9ACTO
(B3TMP1)		 
[query] 3 - 3868 (3868)
[subject] 12 - 3852 (3921)
 0.0 3016   49%
Product
Polyketide synthase
Gene
KijS4
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
48
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 35 - 3860 (3868)
[subject] 3266 - 6849 (10223)
(11 hsp)		 0.0 2896   47%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
49
 C0SMW2_9ACTO
(C0SMW2)		 Jump to Tauto_00090 
[query] 29 - 3849 (3868)
[subject] 1749 - 5460 (5770)
(4 hsp)		 0.0 2894   47%
Product
Type I modular polyketide synthase
Gene
ttmH
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
51
 Q93HJ3_STRAW
(Q93HJ3)		 Jump to Oligo_00100 
[query] 3 - 3867 (3868)
[subject] 2 - 3865 (3939)
(2 hsp)		 0.0 2880   47%
Product
Modular polyketide synthase
Gene
olmA3
SAV2897
SAV_2897
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
52
 A0FCL3_STRVO
(A0FCL3)		 Jump to Merid_00040 
[query] 35 - 3868 (3868)
[subject] 7422 - 11212 (11604)
(17 hsp)		 0.0 2880   46%
Product
MerC
Gene
merC
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17159202
Organization of the biosynthetic gene cluster in Streptomyces sp. DSM 4137 for the novel neuroprotectant polyketide meridamycin.(Microbiology) [2006]
54
 Q9ADL6_SORCE
(Q9ADL6)		 Jump to Soraph_00070 
[query] 31 - 3489 (3868)
[subject] 2089 - 5539 (6315)
(10 hsp)		 0.0 2867   49%
Product
Soraphen polyketide synthase A
Gene
sorA
Organism
Sorangium cellulosum
Polyangium cellulosum
1uniprot[Pubmed] 12039053 [Medline] 22035375
Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.(Gene) [2002]
55
 Q6W5P7_9ACTO
(Q6W5P7)		 Jump to FR008_00190 
[query] 1 - 3456 (3868)
[subject] 1 - 3370 (7771)
(8 hsp)		 0.0 2845   51%
Product
FscE
Gene
fscE
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
56
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 35 - 3862 (3868)
[subject] 3622 - 7528 (16990)
(14 hsp)		 0.0 2843   45%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
59
 B6ZK65_STRLS
(B6ZK65)		 Jump to Lasal_00140 
[query] 31 - 3012 (3868)
[subject] 1746 - 4685 (5429)
(8 hsp)		 0.0 2726   53%
Product
Putative polyketide synthase
Gene
lsd12
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]
61
 B2HF44_MYCMM
(B2HF44)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3401 (4187)
(4 hsp)		 0.0 2721   47%
Product
Polyketide synthase, Pks12
Gene
pks12
MMAR_3025
Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
1uniprot[Pubmed] 18403782
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008]
62
 A0PQM7_MYCUA
(A0PQM7)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3405 (4191)
(4 hsp)		 0.0 2720   47%
Product
Polyketide synthase, Pks12
Gene
pks12
MUL_2266
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 17210928
Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer.(Genome Res.) [2007]
63
 Q7VES2_MYCBO
(Q7VES2)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2705   47%
Product
Probable polyketide synthase pks12
Gene
pks12
Mb2074c
Organism
Mycobacterium bovis
1uniprot[Pubmed] 12788972 [Medline] 22709107
The complete genome sequence of Mycobacterium bovis.(Proc. Natl. Acad. Sci. U.S.A.) [2003]
65
 D7CC08_STRBB
(D7CC08)		 
[query] 35 - 3012 (3868)
[subject] 1812 - 4775 (5530)
(8 hsp)		 0.0 2696   52%
Product
Putative type I polyketide synthase
Gene
pks5-2
SBI_01382
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
66
 C1APW8_MYCBT
(C1APW8)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2692   47%
Product
Putative polyketide synthase
Gene
pks12
JTY_2062
Organism
Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)
1uniprot[Pubmed] 19200449
Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guerin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains.(Vaccine) [2009]
68
 A1KK94_MYCBP
(A1KK94)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2692   47%
Product
Probable polyketide synthase pks12
Gene
pks12
BCG_2067c
Organism
Mycobacterium bovis (strain BCG / Pasteur 1173P2)
1uniprot[Pubmed] 17372194
Genome plasticity of BCG and impact on vaccine efficacy.(Proc. Natl. Acad. Sci. U.S.A.) [2007]
69
 Q7D7J7_MYCTU
(Q7D7J7)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2691   47%
Product
Polyketide synthase
Gene
MT2108
Organism
Mycobacterium tuberculosis
1uniprot[Pubmed] 12218036 [Medline] 22206494
Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.(J. Bacteriol.) [2002]
75
 A0ACH2_STRAM
(A0ACH2)		 
[query] 21 - 3012 (3868)
[subject] 26 - 2940 (3661)
(6 hsp)		 0.0 2689   53%
Product
Putative polyketide synthase B
Gene
SAMR0466
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
77
 O53490_MYCTU
(O53490)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3366 (4151)
(4 hsp)		 0.0 2686   47%
Product
Probable polyketide synthase pks12
Gene
pks12
Rv2048c
Organism
Mycobacterium tuberculosis
1uniprot[Pubmed] 9634230 [Medline] 98295987
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.(Nature) [1998]
79
 Q73Z07_MYCPA
(Q73Z07)		 
[query] 10 - 3483 (3868)
[subject] 10 - 3384 (4170)
(4 hsp)		 0.0 2665   47%
Product
Pks12
Gene
pks12
MAP_1796c
Organism
Mycobacterium paratuberculosis
1uniprot[Pubmed] 16116077
The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005]
81
 B1W5P3_STRGG
(B1W5P3)		 
[query] 3 - 3862 (3868)
[subject] 2 - 3440 (3522)
(3 hsp)		 0.0 2659   44%
Product
Putative type-I PKS
Gene
pks3-3
SGR_6371
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
82
 C0SMW3_9ACTO
(C0SMW3)		 Jump to Tauto_00100 
[query] 1 - 3012 (3868)
[subject] 1 - 2953 (5710)
(7 hsp)		 0.0 2655   52%
Product
Type I modular polyketide synthase
Gene
ttmI
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
83
 B5M9L2_STRLS
(B5M9L2)		 Jump to Lasal2_00200 
[query] 1 - 3026 (3868)
[subject] 1 - 3002 (3679)
(5 hsp)		 0.0 2653   52%
Product
Lasalocid modular polyketide synthase
Putative polyketide synthase
Gene
lasAV
lsd15
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]
85
 A0ACI3_STRAM
(A0ACI3)		 
[query] 3 - 3010 (3868)
[subject] 2 - 2941 (5447)
(8 hsp)		 0.0 2647   52%
Product
Putative type I modular polyketide synthase
Gene
SAMR0477
Organism
Streptomyces ambofaciens ATCC 23877
1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]
2uniprot
Multiple biosynthetic and uptake systems mediate siderophore-dependent iron acquisition in Streptomyces coelicolor A3(2) and Streptomyces ambofaciens ATCC 23877.(Microbiology (Mosc.)) [2006]
86
 D7C2B7_STRBB
(D7C2B7)		 
[query] 8 - 2621 (3868)
[subject] 7 - 2583 (2716)
(3 hsp)		 0.0 2640   56%
Product
Type I modular polyketide synthase
Gene
pks3-1
SBI_00650
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
87
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 29 - 3012 (3868)
[subject] 7193 - 10160 (10827)
(15 hsp)		 0.0 2607   51%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
89
 Q9L4X2_9ACTO
(Q9L4X2)		 Jump to Nysta_00060 
[query] 6 - 3010 (3868)
[subject] 12 - 2978 (5435)
(8 hsp)		 0.0 2596   52%
Product
NysJ
Gene
nysJ
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
90
 Q9KID7_STRHY
(Q9KID7)		 Jump to Asco_00170 
[query] 5 - 3862 (3868)
[subject] 4 - 3425 (6396)
(7 hsp)		 0.0 2595   45%
Product
FkbA
Gene
fkbA
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
91
 E0D203_9ACTO
(E0D203)		 Jump to FD891_00020 
[query] 4 - 3012 (3868)
[subject] 27 - 3065 (5571)
(7 hsp)		 0.0 2581   51%
Product
Polyketide synthase
Gene
gfsB
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
92
 A4FDM8_SACEN
(A4FDM8)		 
[query] 10 - 3018 (3868)
[subject] 1042 - 4016 (4132)
(7 hsp)		 0.0 2545   51%
Product
Modular polyketide synthase-
Gene
SACE_2875
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
94
 D2CKL6_PSEAH
(D2CKL6)		 
[query] 6 - 3010 (3868)
[subject] 13 - 2969 (5425)
(7 hsp)		 0.0 2524   51%
Product
CppJ
Gene
cppJ
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
95
 E9KTB8_STRKN
(E9KTB8)		 
[query] 5 - 3862 (3868)
[subject] 4 - 3453 (6408)
(7 hsp)		 0.0 2522   44%
Product
Polyketide synthase
Gene
fkbA
Tcs_SK_034
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
96
 C6W8K9_ACTMD
(C6W8K9)		 
[query] 28 - 3862 (3868)
[subject] 980 - 4535 (4575)
(3 hsp)		 0.0 2504   46%
Product
Acyl transferase
Gene
Amir_3197
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
97
 E9KTI5_9ACTO
(E9KTI5)		 
[query] 5 - 3867 (3868)
[subject] 4 - 3455 (6418)
(6 hsp)		 0.0 2483   44%
Product
Polyketide synthase
Gene
fkbA
Tcs_11604BP_031
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
98
 B2HNF5_MYCMM
(B2HNF5)		 
[query] 4 - 3011 (3868)
[subject] 3 - 2991 (5495)
(7 hsp)		 0.0 2477   48%
Product
Type I modular polyketide synthase
Gene
MMAR_3798
Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
1uniprot[Pubmed] 18403782
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008]
100
 P95814_STRSQ
(P95814)		 
[query] 5 - 3862 (3868)
[subject] 4 - 3466 (6420)
(8 hsp)		 0.0 2468   43%
Product
FK506 polyketide synthase
Gene
fkbA
Organism
Streptomyces sp
1uniprot[Pubmed] 9063448 [Medline] 97217427
Structural organization of a multifunctional polyketide synthase involved in the biosynthesis of the macrolide immunosuppressant FK506.(Eur. J. Biochem.) [1997]