Merid_00020
Merid_00030 : CDS information
Location
| Organism | Streptomyces violaceusniger |
|---|---|
| Strain | DSM 4137 |
| Entry name | Meridamycin |
| Contig | DQ885223 |
| Start / Stop / Direction | 29,830 / 51,366 / + [in whole cluster] 29,830 / 51,366 / + [in contig] |
| Location | 29830..51366 [in whole cluster] 29830..51366 [in contig] |
| Type | CDS |
| Length | 21,537 bp (7,178 aa) |
Annotation
| Category | 1.1 PKS |
|---|---|
| Product | polyketide synthase |
| Product (GenBank) | MerB |
| Gene | |
| Gene (GenBank) | merB |
| EC number | |
| Keyword | |
| Note | |
| Note (GenBank) |
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| Reference |
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| Related Reference |
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PKS/NRPS Module
| 4 |  | ethylmalonyl-CoA |
| 5 |  | methylmalonyl-CoA |
| 6 |  | methylmalonyl-CoA |
| 7 | | methylmalonyl-CoA |
Sequence
>polyketide synthase [MerB] MENEEKLRHYLKEVTKDLRQTRQRLEDIEAKSREPIAIIGMSCRFPGGIATPEALWDLVR EGGDAVSDFPTDRGWDTEDLYDPAGGSGKSVTRYGGFLHGIADFDAALFGISPREAIAMD PQQRLMLETSWEAFERAGVHRDAVRGSRTGVFIGTNGQDYATLLSAARDEVQGHLGTGSA ASVLSGRVAYTFGLEGPTVTVDTACSSSLIALHLAVQALRNGECELALAGGVTVMTTTNT FVELSKQGGLAPDGRSKAFAAAADGTGWGEGAGVLLVERLSDAERHGHPVLAVVCGTAAN QDGASNGLTAPNGPAQRRVIRAALSNAQLSTGDVDVVEAHGTGTRLGDPIEAQALLDTYG QDREQPLWLGSVKSNLGHAQAAAGVAGASDGLAMRHGVLPRTLHVDEPTPHVDWSAGAIR LLTERTPWPETDRPRRAGVSAFGVSGTNAHVIVEQAPETEPIEPSRIEPVAVPCVLSGQG EAGLRAFAARLADVATEAHPGDLGWTLATTRSALSHRAVVIGSTPADLRSGLAAVAAGEP APNVVEGVAGPDTGVVLVFPGQGSQWAGMAVELLDTSPAFARRFAECARALEAHLDWSIE DVVRSVPGAPSLDLIEVVQPVLFTMMVSLAELWSSYGITPSAVVGHSQGEIAAACVAGAL SLEDAAKVVVLRSRLFAETLVGNGAIASVALPAEQLATRIEPWGERLAVAGVNGPAAATV AGDPQSLEEFVAACVADGVRARVVPATVASHGPQVEPLRERLLALLADVAPRQSTVPFYS TVTGGLLDTTELDADYWFWNARKPIDFLGALHALFADGHRFFVESSTHPALTMGIQDTAD ASGESVVVTGSLRRGEGGLAQFCSAVARLHVHGVRVDWPAAFGAARRVELPTYPFQRERY WLTPRPGHGDASALGLGALDHPLLGATAVLPESGGCLLTGRLSLATHPWLADHALSGVVL FPGAGFVELVLQAGLWLGCGVVEELTLEGPLVFSERGGVEVQVVVGGVGEGGVGGGGCRS VSVFSCRGGEWVRHAVGVLGVGAGVVSGVEVWPPVGAVRVGVEGVYEGLAERGYVYGPVF QGLRDAWRRGDEVFVEVAVPAEARGDAARCAIHPALLDAALHGVRFGDFVSDDDQAYVPF SWTGVTLNAVGATALRVTLSPAGRDAIALRATDTTGAPVLSARSLALRPLSAQQLDDTRG SRTDALHRVEWVDASGAVAAGGEVASRTEVVRVVSEGADVVGEAYGHVLGVLERVRAWVG DEDLAGERLVVVTRGAVDVGGGVEDVAGAAVWGLVRSAQSENPGRLVLVDTDDVEGVGGV LPGVLALGEEQVVVRSGVVRVPRLGRVRVSGEVSGVFGSGAVLVTGGTGVLGGVVSRHLV VRHGVSRLVLLSRRGAEAEGAAELRAELEGAGAEVVIAACDAADGEALAGVLAGLPEGFA LSGVVHAAGVLDDGLLTSLTRERVEPVLRAKVDAAWNLHELTAGMNLSALVFFSSAAGVL GNAGQSSYAAANGFLDALAAHRRARGLPAVSIAWGFWEERSELTKHLSADDLARAHAVPM PTSQALDLFDAALAADEAMVLAAPLDPRAWSDADNPPAVLRDLVRPRIRRAAEVVDASGS ASALEHRLAAVDRSEWDQVVRELVRNHIAAVLRHASAESVDTSRTFQEIGFDSLTAVELR NRISAATGVRLPATAVFDYPTPRALADHLLAEALGKDIGAAAATPAGAALVADDPIVIVG MSCRYPGGITSPEALWDLVRSGGDAISALPTDRGWDLDGLYDPDPDRPGRSYARSGGFVY DAAEFDAAFFGISPREAAAMDPQQRLLLEASWEAFERAGIPATSVKGERIGVFTGVMHHD YLTRLSITPDGVEGYLGTGAAAGVASGRVAYTFGLEGPAVTVDTACSSSLVALHLAIQAL RLGECSLALAGGVTVMSTPTVFVEFSRQRGLASDGKCKAFAGAADGTGFAEGIGMLLVER LSDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSAVDVDAVEA HGTGTTLGDPIEAQALLATYGQGRDADRPLLLGSIKSNIGHTQAAAGVAGVIKMVMAMGH GVLPQTLHIDEPTPHVDWSTGAVRLLGEHTEWPEAGRPRRAGVSSFGISGTNAHLILEQA PLPTTAERPDDAEPGDAKSGDVRPGDVRPDDVRPRAAGPGAVVPWILSGRDRRALRAQAE RLRAHVASHPDLSVADIGFSLLTSRAVLEHRAVVLGGDHAELSAGLTALAQDEPAPGVVE ALDAAEPGRKVVFVFPGQGSQWAGMALELLESAPVFARRMGECAEALAPLVEWSLPDVLA DERALGRVDVVQPVLWAVMVSLAELWRSYGVAPSAVVGHSQGEIAAACVAGGLSLADGAR VVVLRGKALLALSGRGGMVSVPVPADRLRDRPGVSIAAVNGPSSTVVSGGDEALDAVLVE FPAAKRIPVDYASHSPQIDGIRDELLKALAPIEPRTAAIPFHSTVTGRPIDTAELDADYW YRNLRETVELERVTRAAVEDGHHTFIEISPHPVLTTGLRETLDDADAHGGLVLASLRRDD GGLTRFRTALAEAYAYGVEVDWLSVFPGARRVELPTYAFQRERYWLDAPTAEAPTSAIDA EFWAAVEREDLESLAATLRVDGQPLREVLPALSQWRRERRDVSTIDSWRYKIRWKPLTPP ATCPTGTWLVVVSHAEAEHEWVAGVTGALTRHGAEPLVVVLGEPELDRAALAARLGAALA DTPRVSGVVSLTALDESPHPAYPSVPQGYAMTLLLSQALGDAGVEAPLWCLTQRGVSLGD GGGNRGGAGGRGDEGNGSGNGNSTGSGSGNGPGEGDGDRDVAVSRKQALTWGLGKVIALE QPLRWGGLIDLPEGVAPYAQDYLVGVLAGTSDEDQVAIRPTGLFGRRLAHAPAPERGGAW QPRGTVLVTGGTGALGGHVARWLAAQGAEHVVLTSRRGMAAPGAERLAGELEALGARVTV AACDVGDRDALAALLTEVGPLTAVVHTAAVLDDATLNSLTTEQLQRVLRVKTDGAVHLHE LTRDMELSAFVLFSSLSGTLGAPGQGNYAPGHVFVDTLAEQRRAEGLVATSIAWGLWAGD GMGEGGVGEVARRHGVPEMAPEMAVAAMARAVEQDDTVVTVAEIDWDRHYVAFTATRPSP LLSDLPEVRALIDAGVGQESAEPGHERSEFAERLAGMADADRNRALLDLVRRHVAVVLGH TGPDAIDPGRAFHEIGFDSVTAVELRNRLNRATGLRLPATVTFDQPTPLAMARYLRGELL HDGQDRSAPARPVRTTGAVDDEPIAIVGMSCRFPGDVASPEDLWRLLADGSDAIGEFPEN RGWDTAHLFHPDPDHRGTSSTRAAAFVSGAGEFDAGFFGISPREAVAMDPQQRLLLEVSW EALERAGIDPSTLRGSETGVFTGTNGQDYASLLKADETGDFEGRVGTGNSASVMSGRISY VLGLEGPALTVDTACSSSLVALHLAVRALRSGECSLALAGGASVMTTTGIFVEFSRQRAL AADGRCKAFAAGADGTGWGEGVGMLVVERLSDAERNGHRVLAVVRGSAVNQDGASNGLTA PNGPSQQRVIRQALASAGLSAVDVDVVEAHGTGTTLGDPIEAQALLATYGQGRDVDRPLL LGSIKSNIGHTQAAAGVAGVIKMVMAMGHGVLPQTLHIDEPTPHVDWSTGAVRLLDEQTD WPETARPRRAGVSAFGVSGTNAHVILEQAPAPTAEPELSPERDETRAVPWVVTGASEAGV RAQAARLMAFVDDRPELRPVDIGWSLVSTRAALPHRAVVVGGDRDELVRELEAVAGGSAA IGEARTHSGVVFVFPGQGSQWVGMALELVESSSVFAGRLGECADVLAPLVEWSLWDVLGD EVALSRVDVVQPVLWAVMVSLAELWRSFGVVPSVVVGHSQGEIAAACVAGGLSLEDGARV VALRSRALLALSGRGGMVSVPVPADRLRDRPGLSVAAVNGPVSTVVSGSVEALDAVLEEF PEAKRIPVEYASHSVQVEEIREGLAEALASVRPRTGEVPFYSTVTGRLMDTVELDAEYWY RNLRETVEFRSAVEGLLELGHTVFVEASPHPVLTVGIQDTADATDTTHTDILVTGSLRRD DGGLVRFLSTVGRLFTAGVPVEWQPLFAAAGARRVDLPTYAFQHEWFWLDPVRGASDVGG AGLAGLAHPLVSAVLPLPESDGCVLTGSLSSATHPWLRDHAVLDKVLLPGTGFVELALQA GLHLGCRTLDELTLQAPLVLPAHGDVQIQVAVGGPDDSGRRPVTVYSRPGQDRTWVRHAT GSVSPGGETATVDRTVWPPVDATPVDLTGVYAEMNTRGYAYGPVFQGLRAAWRRGDEVFA EVVLSETAESDAGRCAVHPALLDAALHGAGLGTFVTEPGRPHLPFAWTGVSLHAVGATTL RVVLSPAGPDAISLLAMDGTGAPVLTADSLALRPVSGGTRGGAHNDSLFRVDWTELALAA SDTSDEVAFPVVESLAQLTGPGAPQPVHGAVVFRPFATEASATEAPATEASVAGATDATG AADTTEENPEDVYALTSRVLEVAQAWLADDRFGDARLVVVTRGAVATRPGEDPESLAAAA VWGLIRTAQTENPGRFVLVDTVDEDPSVSSVSSVSSTSSVVSALPAVLATDEPQVAIRAG KALVPRLVRAASSALPVPAETDTWRLEADGQGTLENLVLAPHAEASRPLATHEIRVAVRA AGVNFRDVLLALGMYPDKAGLLGSEAAGTVLEIGSGVAGVAPGDRVMGLFSGAFGPVAIT DHRLVAPIPAGWSFPQAAATPIAFLTAMYALIDLADVRSGESVLVHAAAGGVGMAAVQVA RWLGAEVFATASPAKWDAVRACGVAQQRIASSRSTEFADRLRSDAPGGVDVVLNSLTGEL LNASLGLLRPGGRLIEMGRTDLRDAEEVMARHGVSYRAFELLDAGPDRIGRLLTELLSLF RQGVFTPLPLRVQDVRQASDAFRHLSQARHIGKLALTIPRPLSGGTALITGGTGTLGGLV ARHLVREHGVTELVLVGRRGDTAPGAAELLTELEAAGARVRVVACDVSDREATAALVASL PNLRSVVHTAGVLDDAVIGSLTPERLRTVLRPKADAAWHLHELTRDRDLAEFVLFSSAAG VLGGPGQGNYAAANAFLDALAARRRAQGLPATSLAWGFWEQRSGLTEHLTTDRLARSGVL PLSTDEGLALFDAARATGDTLLVPMRYEPSAPGPEPVPALLRGLVRAPLARALPGPADGV GNGVTEGLTGLAVDERLGVLLDLVRREAAAVLGHGGPQSVTPRRPFKELGFDSLSAVELR NRLRTATGRRLEATLIFDHPTPAALARHLDAELFGATDVAAPVPAPTVAHPADERIAIVG MSCRLPAGVDSPEALWTLLMSGTDAISELPTDRGWSLDALYDQDPSRPGTTYAKTGGFLK NAADFDAGFFTISPREALAADPQQRLWLEACWEAFERAGIDPLALKGTRTGVFAGAASTT YGAGQAAAPDGSEGYLLTGNSTSVISGRVAYTLGLEGPAVTVDTACSSSLVSVHWACESL RRGESTLALAGGVAVMTTPDLLVEFSRQRGLAPDGRCKSFAAAADGTGFAEGAGVLVLER LSDAERNGHQVLAVIRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLASQEVDAVEA HGTGTTLGDPIEAQALLATYGQDRDPDRPLLLGSVKSNIGHTQAAAGAAGLIKMVLALRN GVLPRTLHVDEPSPHVDWSAGAMELLTEQTTWPDRDRPRRAGVSAFGVSGTNAHVILEQA PKPDENGEPDTGRSGLPAVPWVLSGAGAAGLRAQAQRLASFVRENPELDPVDVGWSLVAT RAALSHRAVVVGADRTELLRELDAVQSVGAAEAGRDVVFVFPGQGSQWVGMALELVESSS VFAGRLGECADVLAPLVEWSLWDVLGDEVALSRVDVVQPVLWAVMVSLAELWRSFGVVPS VVVGHSQGEIAAACVAGGLSLEDGARVVALRSKALLALSGRGGMVSVPVSADQLRDRPGL SVAAVNGPVSSVVSGPVEVLDAVLEEFPEAKRIPVDYASHSSQVEEIRGELAEALVSVRP RTGEVPFYSTVTGRLMDTVELDGEYWYRNLRETVEFQSTVEHLMREGHTVFVEASPHPVL TVGIQDTADATVTDIVITGSLRRDEGGVRRFLTSLAEVSVRGVEVNWWTAFDGAGARRVD LPTYAFQRERFWLAPSTGTGDAYGLGLGAVDHPLLGAAVPLPDADGCVLTGALSLAGQPW LADHSVLGMVLLPGTAFVELALQAGARFGCDTLEELTLHEPLVLPEQETVQLQVSVGGPD DLGSRPFTVFSRREGDWTRHAGGTLCVGEHGDPPANPSVWPPADARPVDVAELHMTMAER GYQYGPAFQGLRKAWIRDSEVFLDVALPELVRGDAARCGVHPALLDAALQGIGLGAFVSE PGRAHLPFSWSGVTLHAVGATTVRVTLSPAGPDAVAIRMTDTIGAPVLSIDVLAMRPLAE QRLLEAGGPRGDALFRLDWTELPVPTGATGPRALSWGLLGGHDEPRLTAALTAVGVSPQR HRDLASIDQVPDVLVLPCLPEADDGPAPEATSSTLGRVLEVVREWLGDARYTDTRLVVLT RRAVATSTGDDVEDLAAAAVRGLLRTAQQENPDRLVVIDHDDSDLGVLPAVLATGEPEAA IRAGTVLVPRLVKAAVPDGKTPAWDTGTVLITGGTGTLGGLVARHLVTTHGARDLVLASR GGDTAPGAVELATELEALGASIRVAACDVADRAQLTALLDTIPALRAVVHTAGVVDDGVI GSMTADRVEAVLRPKANAAWHLHELTRRLDLDAFVLFSSATGVLGSAGQGNYAAANAFLD ALAVHRRAQGLPAVSVAWGLWEQRSGLTAHLSEQDMARMTRTGAIPLSDERGLELFDAVC RSGEATLVATPLHLRAVAATGTVPPVLSALAPAPPRRATEAGDGGVALRQSLAELSGAEQ SQAVRELVRGQVAAVLRHPDGSAIDPVRTFQEIGFDSLTAVELRNRLGASTGIRLAATAI FDYPTPATLAEHLLAEIVPETADPVAARLGELDKVAAMISAMGEDDTLREQLSSRMETIV AMWADLHRPERSSRVGRDLESASLDDMFGIIDQELDGS
>polyketide synthase [MerB] GTGGAGAATGAAGAGAAACTTCGTCACTACCTCAAAGAGGTCACGAAGGATCTGCGGCAG ACCCGTCAGCGCCTTGAGGACATCGAGGCGAAGAGCCGCGAGCCCATCGCGATCATCGGC ATGAGCTGCCGTTTCCCCGGTGGCATCGCAACACCGGAAGCGCTGTGGGACCTGGTGCGC GAGGGCGGCGACGCGGTGTCGGACTTCCCGACCGACCGCGGATGGGACACGGAGGACCTC TACGACCCCGCGGGCGGCTCCGGCAAGTCCGTCACCCGCTACGGGGGATTCCTGCACGGC ATCGCCGATTTCGACGCCGCGCTCTTCGGGATCTCCCCCCGCGAGGCCATCGCGATGGAC CCACAGCAGCGGTTGATGCTGGAAACCTCCTGGGAGGCGTTCGAGCGGGCCGGTGTCCAC CGTGACGCGGTGCGGGGCAGCCGGACCGGAGTGTTCATCGGCACCAACGGCCAGGACTAC GCCACGCTGCTCAGCGCTGCCCGCGACGAGGTGCAGGGCCACCTCGGCACGGGCAGCGCG GCGAGCGTGCTCTCGGGACGGGTCGCCTACACCTTCGGTCTCGAAGGGCCGACGGTCACC GTGGACACGGCGTGTTCCTCCTCGCTGATCGCCCTACACCTGGCCGTTCAGGCACTGCGC AACGGGGAGTGCGAGCTGGCGCTGGCGGGCGGTGTCACGGTGATGACGACGACGAACACC TTCGTCGAGCTGTCCAAGCAGGGTGGGCTGGCGCCGGACGGCCGGTCCAAGGCGTTCGCG GCGGCGGCGGACGGCACCGGCTGGGGCGAGGGCGCCGGGGTGCTGCTGGTGGAGCGGCTG TCCGACGCCGAACGCCACGGTCACCCGGTGCTGGCGGTGGTGTGTGGCACCGCCGCCAAC CAGGACGGCGCCTCGAACGGGCTGACCGCGCCCAACGGGCCCGCCCAGCGCCGGGTCATC CGCGCGGCACTGTCCAACGCCCAGCTGTCCACGGGCGATGTCGACGTGGTGGAGGCACAC GGCACCGGCACCAGGCTCGGGGACCCGATCGAGGCACAGGCCCTGCTGGACACCTACGGT CAGGACCGGGAGCAGCCGCTGTGGCTCGGATCGGTCAAGTCGAACCTGGGACACGCCCAG GCCGCCGCGGGCGTCGCCGGGGCATCAGATGGCCTCGCCATGCGGCACGGTGTGCTGCCG CGCACCCTGCACGTGGACGAACCGACCCCGCACGTGGACTGGTCCGCCGGTGCGATACGG CTGCTCACCGAGCGGACCCCGTGGCCGGAGACCGACCGGCCGCGCAGGGCCGGGGTCTCC GCCTTCGGGGTGAGTGGCACCAACGCCCATGTGATCGTGGAGCAGGCACCGGAGACCGAG CCCATCGAGCCGTCCAGGATTGAACCGGTGGCGGTGCCCTGCGTGCTTTCGGGCCAGGGC GAGGCCGGTCTGCGCGCGTTCGCGGCCCGGCTCGCCGACGTGGCCACCGAAGCGCACCCC GGCGACCTCGGATGGACCCTGGCCACCACGCGCTCGGCCCTGTCGCACCGTGCGGTGGTG ATCGGGTCCACACCGGCGGACCTGCGGAGCGGCCTCGCGGCGGTGGCCGCCGGAGAGCCG GCCCCGAACGTGGTGGAGGGAGTGGCCGGTCCCGACACCGGTGTGGTCCTCGTCTTCCCG GGACAGGGCTCGCAGTGGGCCGGTATGGCCGTGGAATTGCTGGACACCTCCCCAGCCTTC GCCCGCCGGTTCGCCGAATGCGCCCGTGCCCTGGAGGCGCACCTCGACTGGTCCATCGAG GACGTGGTGCGCTCCGTGCCCGGTGCGCCCTCGCTCGACCTCATCGAGGTCGTCCAGCCG GTGCTGTTCACCATGATGGTGTCCCTCGCCGAGCTGTGGTCCTCCTACGGGATCACTCCC TCGGCCGTGGTCGGCCACTCCCAGGGTGAGATCGCGGCGGCCTGTGTGGCCGGGGCGCTG TCGCTGGAGGACGCGGCCAAGGTGGTGGTGTTGCGCAGCCGCCTCTTCGCCGAAACGCTG GTGGGCAACGGCGCTATCGCGTCGGTCGCCCTGCCGGCGGAACAACTGGCCACCCGGATC GAGCCGTGGGGCGAGCGCCTCGCGGTGGCCGGGGTGAACGGGCCAGCGGCGGCCACGGTG GCCGGTGACCCGCAGAGCCTCGAGGAATTCGTCGCCGCATGCGTGGCGGACGGCGTACGC GCCCGTGTCGTGCCCGCCACCGTGGCGTCCCACGGCCCGCAGGTGGAACCGCTGCGTGAA CGGCTGCTCGCCCTGCTGGCCGACGTGGCGCCACGCCAGTCCACCGTTCCGTTCTACTCC ACGGTGACCGGCGGGCTTCTGGACACCACGGAACTCGACGCGGACTACTGGTTCTGGAAC GCCCGTAAGCCGATCGACTTCCTCGGCGCGCTCCACGCGCTGTTCGCCGACGGCCACCGC TTCTTCGTGGAGTCGAGCACCCACCCCGCCCTGACCATGGGCATCCAGGACACGGCGGAC GCCTCCGGTGAATCCGTGGTGGTCACCGGCTCGCTACGGCGTGGCGAGGGAGGGCTCGCC CAGTTCTGTTCGGCCGTGGCGAGGCTGCATGTGCACGGCGTACGAGTGGACTGGCCGGCG GCCTTCGGCGCGGCGCGGCGGGTGGAGCTGCCGACCTACCCCTTCCAGCGGGAGCGTTAC TGGCTGACGCCCCGGCCCGGCCACGGTGACGCCTCCGCCCTGGGACTCGGCGCGCTCGAC CACCCCCTGCTGGGGGCCACGGCCGTGCTGCCGGAGTCCGGTGGCTGCCTGCTCACCGGC CGGCTGTCCCTGGCCACCCACCCCTGGCTGGCCGATCACGCCCTCTCCGGTGTGGTGTTG TTTCCGGGGGCGGGGTTTGTGGAGTTGGTGTTGCAGGCGGGGTTGTGGTTGGGGTGTGGG GTGGTTGAGGAGTTGACGTTGGAGGGGCCGTTGGTGTTTTCGGAGCGGGGTGGGGTTGAG GTTCAGGTAGTGGTGGGTGGTGTGGGTGAGGGTGGTGTGGGTGGGGGTGGTTGTCGGTCG GTGTCGGTGTTTTCGTGTCGTGGGGGTGAGTGGGTTCGGCATGCGGTGGGTGTTTTGGGG GTGGGGGCTGGTGTGGTGTCGGGTGTGGAGGTGTGGCCGCCGGTGGGTGCGGTGCGGGTT GGGGTGGAGGGGGTTTATGAGGGGTTGGCGGAGCGGGGGTATGTGTATGGGCCGGTGTTC CAGGGGCTGCGGGATGCGTGGCGTCGGGGGGACGAAGTCTTCGTCGAGGTGGCGGTACCG GCGGAGGCTCGGGGCGATGCGGCGCGTTGTGCGATCCATCCCGCTCTCCTCGACGCCGCG CTGCACGGGGTGCGATTCGGCGACTTCGTATCCGACGACGACCAGGCTTATGTGCCGTTC TCGTGGACCGGCGTCACTCTGAACGCGGTCGGTGCGACGGCGCTGCGCGTCACGCTGTCC CCGGCCGGCCGCGACGCGATCGCCCTCCGGGCCACCGACACCACCGGCGCGCCGGTCCTG TCGGCGCGCTCACTGGCCCTGCGCCCGCTCTCCGCCCAACAGCTGGACGACACGCGGGGG AGCAGGACTGATGCCCTCCATCGGGTGGAGTGGGTGGACGCGTCTGGGGCTGTGGCGGCC GGGGGTGAGGTGGCATCGCGGACCGAGGTGGTGCGAGTGGTCTCCGAGGGTGCGGATGTG GTGGGTGAGGCGTATGGGCATGTGCTTGGGGTGTTGGAGCGGGTGCGGGCGTGGGTGGGG GATGAGGATCTGGCGGGTGAGCGGTTGGTGGTGGTGACGCGGGGTGCTGTTGATGTGGGT GGTGGTGTGGAGGATGTGGCCGGGGCGGCGGTGTGGGGTTTGGTGCGGTCCGCGCAGTCG GAGAATCCGGGGCGTCTGGTGCTGGTGGATACCGATGATGTGGAGGGTGTGGGTGGTGTT CTGCCCGGGGTGTTGGCTCTGGGTGAGGAGCAGGTGGTGGTGCGTTCGGGTGTGGTGCGG GTGCCGCGTCTGGGTCGGGTGCGGGTGTCGGGTGAGGTGTCGGGGGTGTTTGGTTCGGGT GCGGTGTTGGTGACGGGTGGTACGGGTGTGTTGGGTGGTGTGGTGTCGCGGCATCTGGTG GTGCGGCATGGGGTGAGCAGGCTGGTGTTGCTGTCGCGTCGTGGTGCGGAGGCCGAGGGT GCCGCGGAGTTGCGGGCGGAGTTGGAGGGGGCGGGTGCCGAGGTGGTGATCGCGGCGTGT GATGCCGCGGATGGTGAGGCTTTGGCCGGGGTGTTGGCCGGGTTGCCGGAGGGTTTTGCG CTTAGTGGTGTGGTGCATGCGGCGGGTGTGCTGGATGACGGGTTGCTGACGTCGTTGACG CGTGAGCGGGTTGAGCCGGTGTTGCGGGCGAAGGTGGATGCGGCGTGGAATCTGCATGAG CTGACGGCCGGGATGAACCTGTCGGCGCTGGTGTTCTTCTCGTCGGCCGCGGGTGTTTTG GGCAACGCGGGCCAGAGCAGTTATGCGGCGGCGAACGGCTTCCTGGACGCGCTGGCGGCT CATCGGCGGGCGCGGGGGCTGCCCGCGGTGTCGATCGCATGGGGCTTCTGGGAAGAACGC AGCGAACTGACCAAGCACCTGTCGGCCGACGATCTGGCGCGTGCTCACGCGGTGCCGATG CCCACCTCCCAGGCACTGGATCTGTTCGACGCGGCACTCGCCGCAGACGAGGCCATGGTC CTGGCCGCACCGCTGGACCCCCGGGCATGGTCGGACGCGGACAACCCGCCCGCCGTCCTG CGCGACCTGGTCCGGCCGCGGATCCGGCGTGCGGCCGAGGTAGTCGACGCCTCCGGATCG GCCTCCGCGCTCGAACACCGGCTGGCCGCCGTGGACCGTTCCGAGTGGGACCAGGTCGTA CGCGAACTCGTGCGCAATCACATCGCGGCGGTGCTGCGCCATGCCTCCGCGGAGTCGGTC GACACCTCGCGGACCTTCCAGGAAATCGGCTTCGACTCGCTGACCGCGGTGGAACTGCGC AACCGGATCAGCGCGGCAACCGGCGTACGGCTGCCAGCCACCGCCGTGTTCGACTATCCG ACACCGCGAGCGCTCGCCGATCACCTGCTCGCCGAAGCCCTCGGGAAGGACATCGGCGCC GCCGCCGCGACACCTGCCGGAGCGGCCCTCGTCGCCGACGATCCCATCGTCATCGTCGGG ATGAGCTGCCGCTACCCCGGCGGGATCACCTCACCGGAAGCGCTGTGGGACCTGGTGCGC TCGGGCGGCGACGCGATATCCGCCTTGCCCACCGACCGAGGATGGGACCTGGACGGTCTC TACGACCCGGATCCGGACCGCCCCGGTAGGTCGTACGCCCGCAGCGGTGGATTCGTCTAC GACGCGGCCGAGTTCGACGCCGCCTTCTTCGGGATCTCGCCGCGCGAGGCCGCCGCCATG GACCCGCAGCAGCGGCTGCTGCTGGAAGCCTCATGGGAGGCGTTCGAGCGTGCGGGCATC CCCGCCACCTCCGTAAAGGGCGAGCGGATCGGCGTGTTCACCGGGGTGATGCACCACGAT TACCTCACCCGCCTGTCGATCACACCGGACGGTGTCGAGGGCTATCTGGGCACGGGCGCG GCGGCCGGCGTCGCCTCGGGCCGCGTGGCGTACACCTTCGGGCTCGAGGGCCCGGCGGTC ACGGTGGACACGGCCTGCTCGTCGTCGCTGGTGGCCCTGCACCTCGCCATACAGGCGCTG CGCCTCGGCGAGTGCTCGCTCGCGCTGGCCGGTGGTGTGACGGTGATGTCCACCCCCACC GTCTTCGTGGAGTTCTCCCGTCAGCGTGGGCTCGCGTCGGACGGCAAGTGCAAGGCGTTC GCGGGAGCGGCGGACGGCACCGGCTTCGCCGAAGGCATCGGCATGCTGCTGGTCGAACGG CTCTCGGACGCACGGCGCAATGGACACCCCGTCCTGGCGGTGGTGCGGGGTAGTGCGGTG AATCAGGATGGTGCGTCGAATGGTTTGACGGCGCCGAATGGTCCGTCGCAGCAGCGGGTG ATTCGTCAGGCGTTGGCGAGTGCGGGGTTGTCGGCGGTGGATGTGGATGCGGTGGAGGCG CATGGTACGGGTACGACGCTGGGTGATCCGATCGAGGCGCAGGCGTTGTTGGCCACGTAT GGTCAGGGTCGGGATGCGGACCGGCCGTTGTTGCTGGGGTCGATCAAGTCGAATATCGGG CACACTCAGGCTGCCGCCGGTGTCGCCGGTGTGATCAAGATGGTCATGGCCATGGGCCAT GGTGTGCTGCCGCAGACTCTGCATATCGATGAGCCCACTCCACACGTGGACTGGTCCACC GGCGCGGTGCGACTCCTGGGTGAGCACACGGAGTGGCCAGAGGCCGGGCGGCCCCGCCGG GCCGGTGTGTCGTCGTTCGGCATCAGCGGAACGAACGCGCACCTGATCCTTGAGCAGGCC CCGCTGCCGACGACAGCGGAGCGACCCGACGACGCCGAGCCCGGCGATGCGAAGTCCGGT GACGTACGGCCCGGTGACGTACGGCCCGATGATGTGCGGCCCCGTGCGGCCGGGCCCGGT GCCGTGGTGCCCTGGATCCTCTCGGGACGCGACCGGCGCGCCCTGCGCGCACAGGCGGAA CGACTGCGCGCACACGTGGCGAGCCACCCGGACCTGAGTGTGGCGGACATCGGTTTCTCG CTGCTGACCAGCCGCGCGGTGCTGGAACACCGTGCGGTGGTGCTCGGCGGCGACCACGCC GAACTTTCGGCCGGGCTGACGGCCCTGGCACAGGACGAACCCGCACCGGGCGTGGTGGAG GCCCTGGACGCGGCCGAACCGGGACGCAAGGTGGTGTTCGTCTTCCCCGGTCAGGGGTCA CAGTGGGCCGGGATGGCGCTGGAACTGCTGGAGTCCGCACCCGTGTTCGCGCGGCGGATG GGCGAGTGCGCCGAAGCGCTGGCTCCGCTGGTGGAGTGGTCGCTGCCGGACGTGTTGGCG GATGAGCGAGCGCTGGGCCGTGTCGATGTGGTGCAGCCGGTGCTGTGGGCGGTGATGGTG TCACTGGCCGAGCTGTGGCGTTCGTACGGTGTGGCGCCATCGGCGGTGGTGGGCCACTCG CAGGGTGAGATCGCGGCGGCGTGTGTCGCGGGCGGCCTGTCCCTGGCGGACGGGGCACGG GTGGTCGTACTGCGCGGCAAGGCGCTGCTCGCCTTGTCGGGCCGGGGCGGAATGGTGTCC GTTCCGGTGCCTGCCGACCGGCTGCGGGACCGGCCCGGGGTCTCCATCGCGGCGGTGAAC GGCCCGTCCTCGACGGTGGTGTCCGGCGGCGACGAGGCGCTGGACGCGGTGCTGGTGGAG TTCCCGGCGGCCAAGCGCATCCCGGTGGACTACGCCTCCCACTCGCCCCAGATCGACGGC ATCCGGGACGAACTGCTGAAGGCCCTGGCGCCGATCGAGCCGCGCACCGCGGCGATCCCC TTCCACTCCACGGTGACCGGACGGCCCATCGACACCGCCGAGCTGGACGCGGACTACTGG TATCGCAACCTGCGCGAGACCGTTGAGCTCGAGCGGGTCACCCGTGCGGCGGTCGAGGAC GGCCATCACACCTTCATCGAGATCAGCCCCCATCCGGTGCTGACCACGGGCCTGCGCGAA ACGCTCGATGACGCGGACGCGCACGGCGGCCTCGTACTGGCCTCACTGCGCCGGGACGAC GGTGGCCTCACCCGTTTCCGCACCGCCTTGGCCGAGGCGTACGCATACGGTGTCGAGGTC GACTGGCTGTCGGTGTTCCCAGGCGCCCGGCGGGTGGAGCTGCCGACGTACGCCTTCCAG CGCGAACGCTACTGGCTGGACGCCCCCACCGCCGAGGCTCCCACCAGCGCGATCGACGCG GAATTCTGGGCCGCCGTCGAGCGCGAGGACCTCGAGTCGCTCGCCGCGACACTGCGCGTC GACGGGCAGCCGCTGCGCGAAGTGCTGCCCGCCCTGTCCCAGTGGCGGCGCGAACGCCGT GATGTCTCCACCATCGACTCATGGCGATACAAGATCCGGTGGAAGCCGCTCACCCCGCCC GCCACTTGCCCGACCGGCACGTGGCTGGTCGTGGTCTCCCACGCCGAGGCCGAGCACGAG TGGGTCGCGGGCGTGACCGGTGCGCTGACCCGTCACGGTGCCGAGCCGCTCGTGGTCGTT CTCGGCGAGCCCGAACTGGACCGTGCCGCGCTGGCCGCCCGGCTGGGCGCGGCGCTGGCC GACACCCCCAGGGTCAGCGGTGTGGTGTCGCTGACCGCGTTGGACGAAAGCCCGCACCCC GCGTATCCCTCGGTCCCCCAGGGATACGCGATGACGCTGTTGCTCTCGCAGGCGCTCGGG GACGCCGGAGTGGAAGCGCCGCTGTGGTGCCTCACCCAGCGTGGCGTCTCGCTCGGCGAT GGCGGAGGCAACCGGGGAGGCGCTGGCGGACGCGGTGACGAAGGCAACGGCAGCGGTAAT GGGAACAGCACTGGTAGTGGCAGCGGCAATGGTCCCGGCGAGGGCGATGGTGACCGTGAT GTTGCCGTCAGCCGGAAGCAGGCCCTGACCTGGGGTCTCGGCAAGGTGATCGCCCTGGAA CAGCCGCTGCGCTGGGGCGGTTTGATCGACCTGCCGGAGGGTGTGGCCCCGTATGCCCAG GACTACCTGGTCGGTGTGCTGGCCGGCACCTCGGACGAGGATCAGGTGGCGATCCGCCCG ACGGGGCTCTTCGGCCGGAGGCTGGCCCACGCACCGGCCCCCGAGCGAGGCGGGGCCTGG CAACCCCGTGGCACCGTACTGGTCACCGGTGGCACCGGAGCGCTGGGCGGCCATGTCGCC CGGTGGCTGGCCGCCCAGGGCGCTGAACACGTGGTACTGACCAGCCGCCGGGGCATGGCC GCGCCCGGCGCCGAACGGCTGGCCGGGGAGCTGGAGGCGCTCGGCGCCCGGGTGACGGTG GCGGCGTGCGACGTCGGTGACCGGGACGCCCTGGCCGCATTGCTGACCGAGGTCGGCCCG CTGACCGCCGTGGTGCACACCGCGGCGGTCCTCGACGACGCCACCCTGAACTCGCTCACC ACCGAGCAGCTGCAACGAGTGCTGCGCGTGAAGACCGATGGCGCGGTGCATCTGCACGAA CTGACACGCGACATGGAGTTGTCCGCGTTCGTGCTCTTCTCCTCGCTTTCCGGCACTCTC GGCGCACCCGGTCAGGGCAACTACGCACCCGGCCACGTCTTCGTGGACACGTTGGCCGAG CAACGGCGGGCCGAGGGCCTGGTGGCCACCTCCATCGCCTGGGGTCTGTGGGCCGGTGAC GGCATGGGCGAGGGTGGTGTAGGCGAAGTGGCCCGCCGCCATGGCGTACCGGAGATGGCA CCGGAGATGGCGGTCGCCGCCATGGCTCGCGCCGTCGAGCAGGATGACACCGTCGTCACG GTCGCCGAGATCGACTGGGACCGGCACTATGTCGCGTTCACCGCGACCCGCCCCAGCCCG CTGCTGTCCGACCTCCCCGAGGTACGTGCGCTGATCGACGCCGGAGTCGGCCAGGAGAGC GCCGAACCGGGCCACGAGCGCTCGGAGTTCGCGGAGCGACTCGCCGGGATGGCCGACGCC GACCGGAACCGCGCGTTGCTGGATCTGGTACGGCGCCATGTCGCGGTCGTACTCGGACAC ACCGGCCCGGACGCGATCGACCCCGGTCGCGCCTTCCACGAGATCGGCTTCGACTCGGTC ACCGCGGTCGAATTGCGCAACCGGCTCAACCGGGCCACCGGCCTACGGCTGCCGGCCACC GTGACGTTCGACCAACCCACCCCGCTGGCGATGGCGCGGTACCTCCGTGGCGAACTGCTG CACGACGGCCAGGACCGATCGGCCCCGGCCCGCCCGGTCCGCACGACCGGCGCGGTGGAC GACGAGCCCATCGCGATCGTGGGCATGAGCTGCCGCTTCCCCGGGGACGTCGCATCCCCC GAGGACCTGTGGCGCCTGCTCGCCGACGGTTCCGACGCCATCGGCGAGTTCCCCGAGAAC CGGGGCTGGGACACCGCGCACCTCTTCCACCCGGACCCCGACCACCGGGGCACCTCCTCC ACCCGAGCGGCCGCGTTCGTCTCCGGGGCCGGTGAGTTCGACGCCGGATTCTTCGGAATC TCCCCGCGGGAGGCGGTGGCGATGGACCCGCAGCAGCGGCTGCTGCTCGAAGTGTCATGG GAGGCGCTGGAGCGGGCCGGGATCGACCCCTCGACCCTGCGGGGCAGCGAGACCGGCGTG TTCACGGGGACGAACGGCCAGGACTACGCGTCGTTGCTGAAGGCGGACGAGACGGGTGAC TTCGAGGGCCGGGTGGGCACCGGCAACTCGGCATCGGTCATGTCCGGCCGGATCTCCTAC GTCCTCGGCCTCGAAGGCCCCGCGCTGACCGTGGACACGGCGTGCTCGTCGTCACTGGTG GCATTGCACCTGGCGGTGCGGGCCCTGCGGTCGGGCGAGTGCTCACTGGCCCTGGCGGGC GGCGCGAGCGTCATGACGACCACCGGCATCTTCGTGGAGTTCTCCCGTCAGCGGGCGTTG GCGGCCGATGGCCGGTGCAAGGCGTTCGCGGCGGGCGCGGACGGCACCGGCTGGGGCGAG GGCGTCGGCATGCTGGTGGTGGAGCGGTTGTCCGATGCTGAGCGGAACGGTCACCGGGTG TTGGCGGTGGTGCGGGGTAGTGCGGTGAATCAGGATGGTGCGTCGAATGGTTTGACGGCG CCGAATGGTCCGTCGCAGCAGCGGGTGATTCGTCAGGCGTTGGCGAGTGCGGGGTTGTCG GCGGTGGATGTGGATGTGGTGGAGGCGCATGGTACGGGTACGACGCTGGGTGATCCGATC GAGGCGCAGGCGTTGTTGGCCACGTATGGTCAGGGTCGGGATGTGGACCGGCCGTTGTTG CTGGGGTCGATCAAGTCGAATATCGGGCACACTCAGGCCGCTGCCGGTGTCGCCGGTGTG ATCAAGATGGTCATGGCCATGGGCCATGGTGTGCTGCCGCAGACTCTGCACATTGATGAG CCCACTCCACACGTGGACTGGTCCACCGGCGCGGTGCGCCTCCTGGATGAGCAGACCGAT TGGCCGGAGACCGCACGGCCCCGCCGCGCCGGAGTGTCCGCCTTCGGGGTGAGCGGCACC AACGCCCATGTGATTCTGGAGCAGGCCCCCGCGCCGACCGCCGAGCCCGAGCTCTCGCCG GAACGCGATGAAACGAGGGCCGTGCCGTGGGTGGTCACGGGTGCGAGCGAAGCCGGTGTC CGCGCACAAGCCGCACGCCTCATGGCCTTTGTCGACGACCGGCCGGAACTCCGCCCGGTG GATATCGGTTGGTCGCTGGTCTCGACCCGCGCGGCTCTGCCTCATCGTGCGGTGGTGGTG GGCGGGGATCGCGATGAACTCGTTCGTGAGCTGGAGGCCGTGGCCGGTGGCAGCGCCGCG ATCGGCGAGGCCCGCACGCATTCCGGGGTGGTGTTTGTCTTCCCTGGTCAGGGGTCGCAG TGGGTGGGGATGGCGTTGGAGTTGGTGGAGTCGTCTTCGGTGTTTGCGGGGCGGTTGGGT GAGTGTGCGGATGTGTTGGCGCCGTTGGTGGAGTGGTCGTTGTGGGATGTGTTGGGTGAT GAGGTGGCGCTCAGTCGGGTGGATGTGGTGCAGCCGGTGTTGTGGGCGGTGATGGTGTCG TTGGCGGAGTTGTGGCGTTCGTTTGGTGTGGTGCCGTCGGTGGTGGTGGGGCATTCGCAG GGTGAGATTGCGGCGGCGTGTGTGGCGGGTGGTCTTTCTCTGGAGGATGGGGCGCGGGTG GTGGCGTTGCGGAGCAGGGCGTTGCTGGCTCTGTCGGGTCGGGGCGGGATGGTGTCGGTT CCAGTGCCTGCCGACCGGCTTCGTGACCGTCCGGGGTTGTCGGTGGCGGCGGTGAATGGT CCGGTGTCGACGGTGGTGTCCGGGTCGGTTGAGGCGCTGGATGCGGTGTTGGAGGAGTTC CCGGAGGCCAAGCGGATCCCTGTGGAATATGCCTCGCATTCGGTGCAGGTGGAGGAGATC CGGGAGGGGCTGGCGGAGGCGTTGGCGTCGGTCCGGCCGCGTACGGGTGAGGTGCCGTTC TATTCGACGGTGACGGGGCGGCTGATGGATACCGTCGAGTTGGATGCGGAGTACTGGTAT CGGAACTTGCGTGAGACGGTGGAGTTCCGGTCCGCGGTCGAGGGGCTGCTGGAGCTTGGT CATACGGTGTTTGTCGAGGCCAGTCCGCATCCGGTGCTGACCGTCGGCATCCAGGACACC GCCGACGCCACCGACACCACCCACACCGATATCCTCGTCACCGGGTCACTGCGCCGCGAC GATGGCGGCCTGGTCCGCTTCCTCAGCACCGTCGGCCGACTGTTCACCGCGGGTGTGCCC GTCGAGTGGCAGCCGCTGTTCGCCGCGGCCGGGGCGCGAAGGGTCGATCTCCCGACCTAT GCGTTCCAGCATGAGTGGTTCTGGCTGGATCCGGTGCGCGGCGCGAGCGATGTGGGCGGC GCGGGCCTTGCCGGTCTCGCTCACCCCTTGGTGAGCGCGGTGTTGCCCCTGCCCGAATCC GACGGCTGTGTGCTGACCGGCTCGCTCTCCTCGGCCACCCATCCTTGGCTGCGCGATCAC GCCGTGCTGGACAAGGTGTTGCTGCCAGGTACCGGGTTCGTCGAACTGGCTCTTCAGGCC GGGCTGCACCTGGGCTGCCGTACGCTGGATGAGCTGACCCTGCAAGCGCCACTCGTACTG CCCGCGCACGGCGACGTACAGATCCAGGTGGCGGTCGGCGGACCGGACGACAGCGGCCGG CGGCCGGTCACGGTGTACTCCAGGCCGGGCCAGGACCGGACCTGGGTACGGCACGCCACC GGCAGCGTCAGCCCCGGCGGTGAAACGGCCACCGTGGATCGGACGGTATGGCCCCCAGTC GACGCCACACCGGTCGACCTCACCGGTGTCTACGCTGAGATGAACACCCGCGGTTACGCG TATGGGCCCGTTTTCCAAGGGCTGCGGGCCGCATGGCGGCGTGGCGACGAGGTGTTCGCC GAGGTGGTCCTGTCCGAGACGGCCGAGAGCGACGCGGGTCGTTGCGCCGTTCACCCCGCC TTGCTCGACGCCGCACTGCACGGCGCCGGACTGGGCACGTTCGTGACCGAACCGGGCCGA CCGCACCTTCCGTTCGCCTGGACCGGTGTCAGCCTGCACGCCGTCGGTGCCACCACTTTG CGGGTCGTCCTGTCGCCCGCCGGGCCGGACGCCATCTCGCTCCTGGCGATGGACGGTACG GGAGCGCCGGTGCTGACGGCGGACTCTCTGGCGCTGCGCCCGGTGTCCGGGGGCACGCGG GGCGGCGCACACAACGACTCGCTGTTCCGAGTGGACTGGACCGAGCTCGCCTTGGCCGCC TCGGACACCTCGGATGAAGTGGCCTTCCCCGTCGTCGAGTCCTTGGCCCAGCTGACCGGG CCGGGGGCACCCCAGCCCGTACACGGGGCCGTGGTGTTCCGGCCTTTCGCCACAGAGGCT TCCGCCACAGAGGCTCCTGCCACAGAGGCTTCCGTCGCAGGGGCCACAGATGCCACAGGG GCCGCGGATACCACCGAGGAGAACCCGGAGGACGTCTACGCGCTCACCAGCCGTGTCCTC GAGGTCGCGCAGGCGTGGCTGGCGGACGACCGGTTCGGGGACGCCCGCCTCGTCGTGGTG ACGCGGGGCGCGGTCGCGACCAGGCCCGGTGAAGACCCGGAGAGCCTTGCCGCAGCCGCG GTTTGGGGCCTCATCCGCACCGCGCAGACCGAGAACCCCGGCCGCTTTGTGCTCGTGGAC ACGGTGGACGAGGATCCGTCGGTGTCGTCGGTGTCGTCGGTGTCGTCCACGTCATCCGTG GTGTCCGCCTTGCCCGCGGTGCTCGCCACCGATGAGCCGCAGGTGGCGATCCGGGCGGGG AAGGCGCTGGTGCCCAGGCTGGTACGGGCCGCCTCGTCGGCGTTGCCGGTACCGGCGGAG ACGGACACCTGGCGGCTGGAGGCCGACGGCCAGGGCACTCTGGAGAACCTGGTCCTCGCG CCCCACGCGGAGGCGTCCAGGCCACTTGCCACACATGAGATCCGGGTGGCCGTGCGTGCC GCCGGGGTCAACTTCCGTGATGTACTGCTCGCTTTGGGGATGTACCCGGACAAGGCCGGT CTGCTGGGCAGCGAAGCCGCCGGGACGGTTCTGGAGATCGGCTCCGGGGTAGCGGGAGTG GCACCGGGAGACCGGGTGATGGGCCTGTTCTCCGGCGCCTTCGGGCCGGTGGCCATCACC GATCACCGACTGGTGGCCCCGATCCCTGCGGGGTGGTCCTTCCCGCAGGCCGCCGCCACC CCGATCGCCTTCCTCACGGCGATGTACGCCTTGATCGACCTGGCCGATGTGCGGAGCGGC GAATCGGTGCTGGTGCACGCCGCGGCCGGTGGCGTCGGGATGGCGGCAGTGCAGGTGGCG CGCTGGCTGGGCGCCGAGGTGTTCGCAACCGCGAGCCCGGCCAAGTGGGATGCGGTACGC GCATGCGGGGTCGCCCAGCAGCGGATCGCCTCCTCCCGCTCGACGGAATTCGCGGACCGC CTCCGCTCGGACGCACCGGGCGGCGTGGATGTCGTACTCAACTCGCTGACCGGCGAACTC CTCAACGCGTCGCTCGGACTGCTGCGTCCCGGTGGACGCCTGATCGAGATGGGCAGGACC GACCTCCGGGACGCCGAGGAGGTGATGGCGCGCCACGGTGTGTCGTACCGGGCCTTCGAA CTGCTCGACGCCGGTCCCGACCGTATCGGCCGACTGCTCACCGAACTGCTCTCACTGTTC CGGCAGGGCGTGTTCACCCCGCTGCCACTGCGCGTCCAGGACGTACGCCAGGCGAGCGAT GCCTTCCGCCACCTCTCCCAGGCGCGCCACATCGGCAAGCTGGCCCTCACCATCCCGCGA CCGCTCTCCGGCGGCACCGCACTGATCACCGGGGGCACCGGGACACTGGGCGGTCTGGTG GCGCGCCATCTGGTGCGGGAACACGGAGTGACGGAGCTGGTGCTGGTCGGCCGCCGTGGT GACACCGCTCCGGGGGCGGCGGAGCTGCTCACCGAGCTGGAGGCCGCCGGAGCCCGGGTG CGGGTGGTCGCATGCGATGTGTCGGACCGGGAGGCGACCGCCGCACTCGTCGCCTCGCTG CCGAACCTGCGGAGCGTGGTGCACACGGCTGGTGTCCTCGACGACGCCGTGATCGGGTCG CTCACCCCGGAGCGGCTGCGGACGGTACTGCGCCCCAAGGCGGACGCCGCATGGCATCTG CATGAACTGACCCGGGACCGGGACCTGGCCGAGTTCGTGTTGTTCTCCTCGGCGGCCGGA GTACTCGGTGGCCCAGGACAGGGCAACTACGCGGCGGCCAACGCCTTCCTCGACGCGCTG GCCGCGCGCCGCCGGGCACAGGGGCTGCCCGCGACCTCGCTGGCCTGGGGCTTCTGGGAG CAGCGCAGCGGACTGACCGAACATCTGACCACCGACCGGCTCGCCCGGTCCGGCGTGCTG CCGCTGTCCACCGACGAGGGGCTGGCCCTCTTCGACGCCGCCCGCGCGACCGGCGACACC CTGCTGGTGCCGATGCGTTACGAACCGTCCGCACCGGGCCCCGAGCCGGTGCCCGCCCTC CTGCGTGGCCTCGTACGCGCTCCGCTCGCCCGAGCCCTTCCAGGCCCGGCCGATGGTGTC GGCAACGGTGTGACCGAGGGCCTCACCGGGCTGGCGGTGGACGAACGCCTCGGTGTCCTG CTCGACCTGGTCCGCCGGGAGGCGGCGGCCGTGCTCGGCCACGGCGGTCCGCAATCGGTG ACACCGCGGCGGCCGTTCAAGGAACTCGGCTTCGACTCGCTCTCCGCGGTGGAACTGCGC AACCGGCTGCGCACGGCGACCGGCCGACGGCTGGAGGCCACCCTGATCTTCGACCACCCC ACTCCGGCCGCGCTCGCCCGCCACCTCGACGCCGAGCTGTTCGGCGCCACCGATGTGGCG GCGCCCGTACCGGCACCGACGGTCGCGCACCCGGCCGATGAACGGATCGCCATCGTCGGC ATGAGCTGCCGGCTCCCCGCCGGAGTGGACTCCCCGGAGGCGCTGTGGACGTTGCTGATG AGCGGCACGGACGCGATATCGGAGCTGCCCACCGACCGCGGCTGGAGTCTCGACGCGCTC TACGACCAGGACCCGAGCCGGCCCGGCACGACATACGCCAAGACCGGTGGCTTCCTGAAG AACGCGGCGGACTTCGACGCGGGATTCTTCACCATCTCCCCGCGAGAGGCGCTGGCCGCG GATCCCCAGCAACGGCTGTGGCTCGAGGCGTGCTGGGAAGCCTTCGAACGCGCCGGTATC GATCCCCTCGCCCTGAAGGGCACCCGCACCGGGGTGTTCGCGGGTGCCGCTTCGACAACG TACGGCGCGGGCCAGGCCGCCGCTCCGGACGGCTCCGAGGGGTATCTGCTCACCGGGAAC TCCACCTCCGTGATCTCCGGCCGCGTGGCCTACACCCTCGGCCTCGAAGGCCCCGCCGTC ACCGTGGACACCGCATGCTCGTCCTCGCTGGTCAGCGTGCACTGGGCGTGTGAGTCCCTG CGCAGGGGCGAAAGCACACTGGCGCTGGCGGGCGGCGTGGCGGTGATGACGACACCGGAC CTGCTGGTCGAATTCTCCCGCCAGCGCGGACTCGCACCGGACGGGCGGTGCAAGTCGTTC GCCGCCGCCGCTGATGGCACCGGGTTCGCCGAAGGCGCCGGAGTGCTCGTCCTGGAACGG CTCTCCGACGCCGAGCGGAACGGCCACCAGGTGCTGGCGGTGATCCGTGGCTCCGCCGTC AACCAGGATGGCGCTTCCAACGGGCTGACGGCGCCGAACGGTCCCTCGCAGCAGCGGGTG ATCCGGCAGGCGCTGGCGAACGCCGGGCTGGCCTCCCAGGAAGTCGACGCGGTCGAGGCG CACGGTACGGGTACGACGCTGGGTGATCCGATCGAGGCGCAGGCCCTGCTGGCCACCTAC GGCCAGGACCGGGATCCGGATCGGCCACTGCTGCTGGGCTCAGTGAAGTCCAACATCGGA CACACCCAGGCGGCCGCGGGCGCCGCCGGACTCATCAAGATGGTTCTGGCGCTGCGCAAC GGCGTACTGCCACGCACCCTGCACGTCGACGAGCCCTCCCCGCACGTCGACTGGTCCGCC GGGGCCATGGAACTGTTGACCGAGCAGACCACGTGGCCCGACCGGGACCGCCCGCGCCGG GCCGGAGTGTCCGCGTTCGGGGTGAGTGGCACCAACGCCCATGTGATCCTCGAACAGGCC CCGAAGCCGGACGAGAACGGCGAGCCGGACACTGGCCGGTCGGGGTTGCCCGCAGTGCCC TGGGTGCTGTCGGGTGCGGGAGCGGCCGGGCTGCGGGCCCAGGCCCAGCGGCTGGCCTCC TTCGTACGGGAGAACCCCGAGCTCGACCCCGTGGACGTGGGCTGGTCCCTGGTCGCGACC CGCGCTGCCCTGTCGCACCGGGCGGTGGTCGTGGGCGCGGACCGCACGGAACTGCTGCGC GAGCTGGACGCGGTGCAATCCGTGGGCGCCGCCGAGGCGGGGCGCGACGTGGTGTTTGTC TTCCCTGGTCAGGGGTCGCAGTGGGTGGGGATGGCGTTGGAGTTGGTGGAGTCGTCTTCG GTGTTTGCGGGGCGGTTGGGTGAGTGTGCGGATGTGTTGGCGCCGTTGGTGGAGTGGTCG TTGTGGGATGTGTTGGGTGATGAGGTGGCGCTCAGTCGGGTGGATGTGGTGCAGCCGGTG TTGTGGGCGGTGATGGTGTCGTTGGCGGAGTTGTGGCGTTCGTTTGGTGTGGTGCCGTCG GTGGTGGTGGGGCATTCGCAGGGTGAGATTGCGGCGGCGTGTGTGGCGGGTGGTCTTTCT CTGGAGGATGGTGCCCGGGTGGTGGCCTTGCGGAGCAAGGCGTTGCTGGCTCTGTCGGGT CGGGGTGGGATGGTGTCGGTTCCGGTGTCTGCCGACCAGCTTCGCGATCGTCCGGGGTTG TCGGTGGCGGCGGTGAATGGTCCGGTGTCGTCGGTGGTGTCCGGGCCGGTTGAGGTGCTG GATGCGGTGTTGGAGGAGTTCCCGGAGGCCAAGCGGATCCCTGTGGACTACGCCTCGCAT TCCTCGCAGGTGGAGGAGATCCGGGGGGAGCTGGCGGAGGCGTTGGTGTCGGTCCGGCCG CGTACGGGTGAGGTGCCGTTTTATTCGACGGTGACCGGTCGGCTCATGGACACCGTCGAG TTGGATGGGGAGTACTGGTATCGGAACCTGCGTGAGACGGTGGAGTTCCAGAGCACCGTC GAACACCTTATGCGCGAGGGCCATACGGTGTTTGTCGAGGCCAGTCCGCATCCGGTGCTG ACTGTCGGCATCCAGGACACCGCCGACGCCACCGTCACCGACATCGTGATCACCGGTTCG CTCCGCCGGGACGAGGGAGGCGTCCGGCGGTTCCTGACGTCACTGGCCGAGGTGTCCGTC CGTGGTGTCGAGGTCAACTGGTGGACGGCCTTCGACGGCGCCGGCGCTCGGCGAGTCGAC TTGCCCACTTACGCGTTCCAGCGTGAGCGGTTCTGGTTGGCGCCATCGACGGGCACGGGC GACGCGTACGGGCTGGGCCTGGGCGCCGTTGACCATCCGTTGCTGGGCGCGGCGGTGCCC CTCCCGGACGCGGATGGCTGTGTGCTGACCGGTGCGCTGTCGCTGGCCGGGCAGCCATGG CTGGCGGACCACTCCGTCCTCGGCATGGTCCTTCTGCCGGGCACCGCGTTCGTGGAGCTC GCGTTGCAGGCGGGGGCACGGTTCGGCTGCGACACGCTGGAAGAGCTGACGCTGCATGAG CCGCTCGTCCTGCCCGAGCAGGAGACCGTGCAGCTCCAGGTGTCGGTCGGCGGCCCGGAT GACCTCGGTAGCCGCCCCTTCACGGTGTTCTCGCGCCGTGAGGGCGACTGGACACGCCAC GCCGGAGGCACCCTGTGCGTGGGCGAGCATGGCGATCCGCCTGCGAATCCGTCGGTGTGG CCACCGGCCGATGCCCGGCCGGTGGATGTCGCCGAGCTGCACATGACGATGGCCGAGCGG GGCTATCAGTACGGACCCGCCTTCCAGGGCCTGCGGAAGGCTTGGATCCGCGACAGCGAG GTGTTCCTCGACGTCGCGTTGCCCGAGTTGGTGAGGGGCGACGCCGCCCGCTGCGGAGTG CATCCCGCGTTGCTGGACGCGGCCCTGCAAGGCATCGGCCTTGGCGCCTTCGTCAGCGAA CCGGGACGGGCCCATCTCCCCTTCTCCTGGAGCGGGGTGACCCTGCACGCGGTGGGCGCC ACCACCGTGCGGGTGACGCTCAGCCCGGCCGGACCGGACGCGGTGGCCATCCGGATGACG GACACCATCGGGGCGCCCGTGCTGTCGATCGACGTCTTGGCGATGCGCCCGCTCGCGGAG CAGCGGCTGCTTGAGGCGGGCGGCCCCCGTGGCGACGCACTGTTCCGGCTGGACTGGACG GAGCTTCCCGTCCCCACGGGGGCCACCGGCCCGCGGGCCCTGTCCTGGGGCCTGCTGGGC GGCCACGACGAGCCCCGACTCACGGCCGCGCTGACCGCGGTCGGTGTGTCACCACAACGC CACCGGGACCTCGCCTCCATCGACCAGGTGCCCGATGTATTGGTCCTGCCGTGTCTGCCC GAGGCGGATGACGGCCCGGCCCCGGAAGCCACCTCGTCCACTCTCGGCCGAGTGCTGGAA GTGGTGCGGGAGTGGCTCGGGGACGCGCGGTACACCGATACCCGCCTGGTGGTGCTCACC CGCCGTGCGGTGGCCACATCCACCGGTGACGACGTGGAGGATCTGGCGGCGGCCGCCGTA CGGGGGCTCCTGCGCACCGCACAGCAGGAGAACCCCGACCGGCTCGTCGTGATCGACCAT GACGACTCGGACCTTGGGGTACTGCCCGCGGTGCTCGCGACAGGGGAACCCGAAGCGGCC ATCCGGGCGGGTACGGTGCTGGTGCCCAGACTGGTCAAGGCGGCCGTACCGGATGGGAAA ACCCCTGCCTGGGACACGGGCACCGTACTGATCACCGGCGGGACGGGGACACTCGGCGGC CTGGTCGCCCGCCATCTGGTGACCACCCATGGCGCGCGTGACCTGGTGCTGGCCAGCCGC GGAGGTGACACCGCGCCCGGTGCCGTGGAACTGGCCACCGAGCTGGAGGCGCTCGGCGCC AGTATCCGCGTCGCCGCCTGCGATGTGGCCGATCGTGCCCAGCTGACCGCGCTGCTCGAC ACCATTCCGGCGCTGCGCGCCGTCGTCCACACCGCCGGTGTGGTGGACGACGGTGTTATC GGCTCGATGACCGCCGACCGCGTGGAGGCCGTCCTGCGGCCGAAAGCGAACGCGGCGTGG CACCTGCACGAGCTGACCCGCCGACTGGACCTGGACGCGTTCGTACTGTTCTCCTCCGCC ACCGGAGTGCTGGGCAGTGCGGGACAGGGCAACTACGCCGCGGCCAACGCCTTCCTCGAC GCGCTGGCCGTGCACCGGCGGGCCCAGGGGCTCCCCGCGGTGTCGGTGGCATGGGGCCTG TGGGAGCAGCGCAGTGGCCTGACCGCACATCTGTCGGAGCAGGACATGGCCCGTATGACC CGCACGGGCGCCATTCCACTCTCCGACGAGCGCGGTCTCGAACTGTTCGACGCCGTGTGC CGGAGTGGCGAAGCCACGCTCGTGGCCACCCCGTTGCACCTTCGTGCGGTGGCGGCCACC GGTACGGTGCCGCCCGTGCTGAGCGCGCTGGCACCGGCCCCGCCGCGCCGGGCCACCGAG GCCGGTGACGGTGGGGTGGCCCTGCGGCAGAGCCTGGCCGAGCTGTCGGGTGCGGAACAG AGCCAGGCCGTACGGGAGTTGGTACGCGGCCAGGTCGCCGCGGTGCTGCGACACCCGGAC GGGTCGGCGATCGACCCGGTGCGGACCTTCCAGGAAATCGGCTTCGACTCGTTGACCGCG GTGGAGCTGCGCAACCGGCTGGGTGCCAGCACCGGAATCAGGCTGGCCGCGACCGCGATC TTCGACTATCCGACACCTGCCACGCTGGCGGAGCATCTGCTCGCCGAGATCGTGCCGGAG ACCGCCGACCCGGTCGCGGCCCGGCTCGGCGAGCTGGACAAGGTGGCCGCCATGATTTCG GCGATGGGCGAGGACGACACCCTGCGCGAGCAGTTGTCCTCTCGGATGGAGACCATCGTT GCGATGTGGGCCGACCTGCACCGTCCGGAGCGGTCGAGCAGGGTTGGGCGGGACCTCGAA TCGGCCTCGCTCGACGACATGTTCGGAATCATCGACCAGGAACTCGATGGGTCATGA
Feature
| BLASTP Database:UniProtKB:2011_09 |
|
|---|---|
| InterPro Database:interpro:38.0 |
IPR001227 Acyl transferase domain (Domain)
IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site (Conserved_site)
IPR006162 Phosphopantetheine attachment site (PTM)
IPR009081 Acyl carrier protein-like (Domain)
IPR011032 GroES-like (Domain)
IPR013149 Alcohol dehydrogenase, C-terminal (Domain)
IPR013154 Alcohol dehydrogenase GroES-like (Domain)
IPR013968 Polyketide synthase, KR (Domain)
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
IPR014043 Acyl transferase (Domain)
IPR015083 Polyketide synthase, docking (Domain)
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
IPR016038 Thiolase-like, subgroup (Domain)
IPR016039 Thiolase-like (Domain)
IPR016040 NAD(P)-binding domain (Domain)
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
IPR020806 Polyketide synthase, phosphopantetheine-binding domain (Domain)
IPR020807 Polyketide synthase, dehydratase domain (Domain)
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain (Domain)
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
IPR020843 Polyketide synthase, enoylreductase (Domain)
|
| SignalP | No significant hit |
| TMHMM | No significant hit |
![[547-679] G3DSA:3.40.366.10](../../img/X2.gif "[547-679] G3DSA:3.40.366.10"){kind=small}
![[4840-4861] PS01162](../../img/P.gif "[4840-4861] PS01162"){kind=small}
![[1643-1709] 1.3e-13 PF00550](../../img/H.gif "[1643-1709] 1.3e-13 PF00550"){kind=small}
![[1633-1750] 1.89999859865865e-28 SSF47336](../../img/B.gif "[1633-1750] 1.89999859865865e-28 SSF47336"){kind=small}
![[1640-1710] PS50075](../../img/M.gif "[1640-1710] PS50075"){kind=small}
![[558-856] 6.59996953923913e-109 SM00827](../../img/R.gif "[558-856] 6.59996953923913e-109 SM00827"){kind=small}
