Griseo_00090 : CDS information

Location

Organism	Streptomyces sp.
Strain	JP95
Entry name	Griseorhodin A
Contig	AF509565
Start / Stop / Direction	9,055 / 9,423 / + [in whole cluster] 9,055 / 9,423 / + [in contig]
Location	9055..9423 [in whole cluster] 9055..9423 [in contig]
Type	CDS
Length	369 bp (122 aa)

Annotation

Category	5.4 hypothetical protein
Product	hypothetical protein
Product (GenBank)	GrhI
Gene
Gene (GenBank)	grhI
EC number
Keyword
Note	It is supposed that this ORF is not involved in griseorhodin A biosynthesis.
Note (GenBank)
Reference	ACC Q8KSY3 PmId [12323376] A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A. (Chem Biol. , 2002) [19175308] Cleavage of four carbon-carbon bonds during biosynthesis of the griseorhodin a spiroketal pharmacophore. (J Am Chem Soc. , 2009) comment [PMID:12323376](2002) griseorhodin A生合成gene clusterのクローニング、シークエンス、異種性発現。 GrhI: Unknown DBに似ているタンパクなし。 --- [PMID:19175308](2009) grhI mutantでもgriseorhodin A産生可能。

Sequence

>hypothetical protein [GrhI]
MSDARLVGTWTTELEDDGKSVFGLASFTGDGGVTCYQVNAKNIGLGNWESTGKDSFHYNF
HILAVNPQGEHVGEAHVFVTGEFVSDDRWEGTGGANFYSPAGDLLRGHEGSRVTARKFGI
DK

>hypothetical protein [GrhI]
ATGAGCGACGCCCGGCTTGTCGGAACCTGGACCACCGAGCTGGAGGACGACGGCAAGTCC
GTGTTCGGACTCGCGTCCTTCACGGGTGACGGCGGCGTCACCTGCTACCAGGTCAACGCC
AAGAACATCGGCCTGGGCAACTGGGAGTCCACCGGGAAGGACTCCTTCCACTACAACTTC
CACATCCTCGCCGTGAACCCGCAGGGCGAGCACGTCGGCGAGGCGCACGTCTTCGTCACC
GGCGAGTTCGTCTCCGACGACCGGTGGGAGGGCACCGGCGGCGCCAACTTCTACTCCCCC
GCCGGCGACCTCCTGCGCGGCCACGAGGGCTCCCGGGTCACCGCCCGCAAGTTCGGCATC
GACAAGTAG

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro	No significant hit
SignalP	No significant hit
TMHMM	No significant hit

Griseo_00080 Griseo_00100