Lasal_00040 : CDS information

Location

Organism	Streptomyces lasaliensis
Strain	ATCC 35851
Entry name	Lasalocid
Contig	AB449340
Start / Stop / Direction	3,666 / 2,923 / - [in whole cluster] 3,666 / 2,923 / - [in contig]
Location	complement(2923..3666) [in whole cluster] complement(2923..3666) [in contig]
Type	CDS
Length	744 bp (247 aa)

Annotation

Category	4.1 transcriptional regulator
Product	putative IclR family transcriptional regulator
Product (GenBank)	putative transcriptional regulator
Gene
Gene (GenBank)	lsd2
EC number
Keyword
Note
Note (GenBank)
Reference	ACC B6ZK55 PmId [19129623] Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis. (Biosci Biotechnol Biochem. , 2009) comment GenBank,Uniprotでは、ATCC31180と登録されている。 S. lasaliensis ATCC35851におけるLasalocid生合成gene clusterの報告。 lsd2: regulation homolog: IclR family transcriptional regulator_Frankia sp. CcI3 機能解析はされていない。株違いS. lasaliensis ATCC31180(GenBank,Uniprotでは、NRRL3382Rと登録されている)には、相同配列はない。
Family/Domain	FD IPR005471, IPR014757 comment [IPR005471] Transcription regulator IclR, N-terminal (Domain) [IPR014757] Transcription regulator IclR, C-terminal (Domain)

Sequence

>putative IclR family transcriptional regulator [putative transcriptional regulator]
MRSGGNHMPQSPHRTASESSMGRGVLKGAFALLDELRRQGGEAGLTQIANACGLPKASTH
RLLHQLLMVGAVERHRGRYRVGGQLYRIGQAWQPHPGLRLAARQPLHGLRAATGASVVVT
VLYEDLALTIASVPGEVEPVAPVRDGMGFTLDTAAGQVLTAGPPRRAAGRPETALLEREQ
VMDGVCCAALPVCSPDGRLRAAITAMVPPHRRLQTVAEHTARAGAAITANLGRAARSTAP
LPPVLRH

>putative IclR family transcriptional regulator [putative transcriptional regulator]
ATGCGTTCCGGGGGGAACCACATGCCACAGTCACCGCACCGCACCGCGTCCGAGTCGTCG
ATGGGCCGAGGCGTCCTGAAGGGGGCGTTCGCACTGCTGGACGAGTTACGGCGGCAGGGG
GGCGAAGCGGGACTCACTCAGATCGCCAACGCCTGCGGGCTGCCCAAGGCGAGCACCCAC
CGGCTGCTGCACCAACTGCTCATGGTGGGCGCCGTCGAACGCCACCGCGGCCGCTACCGC
GTGGGCGGCCAGCTCTACCGGATCGGCCAGGCCTGGCAGCCCCATCCCGGACTGCGCCTG
GCCGCCCGCCAGCCCCTGCACGGGCTGCGCGCCGCCACCGGCGCCAGCGTCGTGGTCACC
GTCCTGTACGAGGACCTCGCGCTGACCATCGCCTCCGTGCCCGGCGAGGTCGAGCCGGTC
GCGCCGGTCCGCGACGGCATGGGCTTCACCCTGGACACCGCCGCGGGGCAGGTGCTCACG
GCCGGCCCGCCCCGCCGGGCGGCGGGCCGGCCGGAGACCGCCCTCCTGGAACGCGAGCAG
GTCATGGACGGGGTGTGCTGCGCGGCCCTCCCGGTGTGTTCGCCCGACGGTCGACTCCGC
GCGGCCATCACCGCGATGGTGCCGCCCCACCGACGGCTCCAGACCGTCGCCGAACACACC
GCCCGGGCCGGCGCCGCCATCACCGCCAACCTCGGCAGGGCCGCGAGGAGCACCGCTCCG
TTGCCGCCCGTGCTGCGCCACTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR005471 Transcription regulator IclR, N-terminal (Domain) PS51077 HTH_ICLR PF09339 HTH_IclR IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain) G3DSA:1.10.10.10 Wing_hlx_DNA_bd IPR014757 Transcription regulator IclR, C-terminal (Domain) PS51078 ICLR_ED
SignalP	No significant hit
TMHMM	No significant hit

Lasal_00030 Lasal_00050