Ovied_00020 : CDS information

Location

Organism	Streptomyces antibioticus
Strain	ATCC 11891
Entry name	Oviedomycin
Contig	AJ632203
Start / Stop / Direction	1,861 / 1,226 / - [in whole cluster] 1,861 / 1,226 / - [in contig]
Location	complement(1226..1861) [in whole cluster] complement(1226..1861) [in contig]
Type	CDS
Length	636 bp (211 aa)

Annotation

Category	5.2 function unknown
Product	pyridoxamine 5'-phosphate oxidase-like FMN-binding domain protein
Product (GenBank)	putative pyridoxine 5-phosphate oxidase
Gene
Gene (GenBank)
EC number
Keyword
Note	It is supposed that this ORF is not involved in oviedomycin biosynthesis.
Note (GenBank)	ORF2
Reference	ACC Q6ZZX1 PmId [15368568] Genetic organization of the biosynthetic gene cluster for the antitumor angucycline oviedomycin in Streptomyces antibioticus ATCC 11891. (Chembiochem. , 2004) comment oviedomycin生合成gene clusterの報告。 ORF2: predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase このORFは、おそらくoviedomycin生合成に関連しないと述べられている。
Family/Domain	FD IPR011576 comment [IPR011576] Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain (Domain) function; pyridoxamine-phosphate oxidase activity, FMN binding

Sequence

>pyridoxamine 5'-phosphate oxidase-like FMN-binding domain protein [putative pyridoxine 5-phosphate oxidase]
MGRFAHLAYTDSVRRVQEEQGSGLLGVRALAQPDTGPDELGPDEAAFLTTRDGFYLASTG
ETGWPYIQFRGGPAGFVHVLDERRLAWAEVRGNRQYITTGNLRTDGRVALFFMDYARQAR
LKLLGRARTQGLDEDPALTERLDQPRTDGKVERLMIVEVEGFNWNCHQHITPRYTEEELE
TALRPVRARMDALEQENARLRARLAELGEQD

>pyridoxamine 5'-phosphate oxidase-like FMN-binding domain protein [putative pyridoxine 5-phosphate oxidase]
ATGGGACGGTTCGCACACCTCGCCTACACGGACAGCGTGCGCCGCGTCCAGGAGGAGCAG
GGCAGCGGCCTGTTAGGGGTGCGCGCCCTCGCCCAGCCCGACACCGGACCGGACGAACTC
GGCCCCGACGAGGCCGCGTTCCTCACCACCCGGGACGGGTTCTACCTGGCCAGCACGGGC
GAGACCGGCTGGCCCTACATCCAGTTCCGCGGCGGCCCCGCCGGCTTCGTACACGTCCTG
GACGAGCGGCGGCTGGCCTGGGCGGAGGTGCGCGGCAACCGGCAGTACATCACCACCGGG
AACCTGCGGACCGACGGCCGGGTCGCGCTGTTCTTCATGGACTACGCCCGGCAGGCCCGC
CTGAAACTGCTGGGCCGGGCCCGCACCCAGGGACTCGACGAGGACCCCGCGCTCACCGAA
CGGCTCGACCAGCCGCGCACCGACGGCAAGGTGGAGCGCCTGATGATCGTCGAGGTCGAG
GGCTTCAACTGGAACTGCCACCAGCACATCACCCCGCGCTACACCGAGGAGGAGCTGGAG
ACCGCCCTCCGGCCCGTCCGCGCCCGCATGGACGCCCTGGAACAGGAGAACGCCCGCCTG
CGCGCCCGCCTCGCCGAACTCGGCGAGCAGGACTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR009002 FMN-binding split barrel-related (Domain) SSF50475 FMN_binding IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain (Domain) PF01243 Pyridox_oxidase IPR012349 FMN-binding split barrel (Domain) G3DSA:2.30.110.10 PNPOx_FMN_bd
SignalP	No significant hit
TMHMM	No significant hit

Ovied_00010 Ovied_00030