Pyrlo_00030 : CDS information

Location

Organism	Actinosporangium vitaminophilum
Strain	ATCC 31673 (=NBRC 14294)
Entry name	Pyrrolomycin
Contig	EF140901
Start / Stop / Direction	3,199 / 2,579 / - [in whole cluster] 3,199 / 2,579 / - [in contig]
Location	complement(2579..3199) [in whole cluster] complement(2579..3199) [in contig]
Type	CDS
Length	621 bp (206 aa)

Annotation

Category	4.1 transcriptional regulator
Product	putative TetR family transcriptional regulator
Product (GenBank)	TetR family regulator
Gene
Gene (GenBank)	pyr3
EC number
Keyword
Note
Note (GenBank)
Reference	ACC A3R4P4 PmId [17158935] Cloning and characterization of the pyrrolomycin biosynthetic gene clusters from Actinosporangium vitaminophilum ATCC 31673 and Streptomyces sp. strain UC 11065. (Antimicrob Agents Chemother. , 2007) comment pyrrolomycin biosynthetic gene clustersに関する文献。 pyr3(206 a.a.): TetR family regulator pyr3自体の機能実験は行われていないが、相同性よりTetR family regulatorと予測している。ただし、pyr3とpyr cluster制御との関連は不明。
Family/Domain	FD IPR001647 comment [IPR001647] Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal (Domain) Function GO:0003677 DNA binding

Sequence

>putative TetR family transcriptional regulator [TetR family regulator]
MPRVSEEHRVARRQQIIDAAHRCIVENGFHQTSMQDVINESGLSAGAVYRYFTGKEELIR
AVAEKASVHFAEAMAKVVSEHPSLSWDQALARLLSGLMSDLDESRAGTARLAVQIWGEAQ
RDPVVAEAALGALVAAQRRMHSLVVQLQDTGRIPKSGDAGQISQALLSFLLGCIVQSMLM
EDVDLEGLAHGLAALPSPVELERAGG

>putative TetR family transcriptional regulator [TetR family regulator]
ATGCCACGAGTAAGCGAGGAGCACCGCGTTGCTCGTCGTCAGCAGATCATTGACGCCGCG
CACCGGTGCATTGTGGAGAACGGCTTCCACCAGACGTCCATGCAGGACGTGATCAACGAA
TCCGGGTTGTCGGCTGGCGCGGTGTACCGCTACTTCACCGGCAAGGAGGAGTTGATCCGG
GCCGTCGCGGAGAAGGCCAGCGTGCATTTCGCCGAGGCGATGGCGAAGGTGGTCAGTGAG
CACCCGTCGCTCTCCTGGGACCAGGCCCTGGCCCGTCTGCTCTCCGGACTCATGTCCGAC
CTGGACGAGAGCCGGGCGGGCACCGCGCGCCTGGCCGTGCAGATATGGGGGGAGGCGCAG
CGCGACCCGGTGGTGGCCGAGGCCGCCCTGGGGGCGCTGGTCGCGGCGCAGCGGCGGATG
CACTCCCTGGTGGTACAGCTCCAGGACACCGGACGGATACCGAAGTCGGGCGACGCCGGG
CAGATCAGTCAGGCGTTGCTGTCCTTCCTGCTCGGCTGCATCGTGCAGTCCATGTTGATG
GAGGACGTTGACCTCGAGGGCCTCGCCCACGGCCTCGCCGCCCTGCCGAGCCCGGTGGAG
CTGGAACGCGCCGGGGGCTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR001647 DNA-binding HTH domain, TetR-type (Domain) PS50977 HTH_TETR_2 PR00455 HTHTETR PF00440 TetR_N IPR009057 Homeodomain-like (Domain) SSF46689 Homeodomain_like IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal (Domain) SSF48498 TetR_like_C IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal (Domain) G3DSA:1.10.357.10 TetR_C IPR023772 DNA-binding HTH domain, TetR-type, conserved site (Conserved_site) PS01081 HTH_TETR_1
SignalP	No significant hit
TMHMM	No significant hit

Pyrlo_00020 Pyrlo_00040