Virg_00080 Virg_00080   Virg_00100 Virg_00100

Virg_00090 : CDS information

close this sectionLocation

Organism
StrainMAFF 10-06014
Entry nameVirginiamycin
Contig
Start / Stop / Direction37,580 / 29,565 / - [in whole cluster]
9,204 / 1,189 / - [in contig]
Locationcomplement(29565..37580) [in whole cluster]
complement(1189..9204) [in contig]
TypeCDS
Length8,016 bp (2,671 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category1.2 NRPS
Productnon-ribosomal peptide synthetase
Product (GenBank)non ribosomal peptide synthetase for virginiamycin S
Gene
Gene (GenBank)visE
EC number
Keyword
  • virginiamycin S
Note
Note (GenBank)
Reference
ACC
PmId
[17350183] Characterization of biosynthetic gene cluster for the production of virginiamycin M, a streptogramin type A antibiotic, in Streptomyces virginiae. (Gene. , 2007)
comment
[PMID:17350183]
virginiamycin M生合成gene clusterの報告。

VisE : NRPS for virginiamycin S

VisE, VisFと相同性を示すpristinamycin I 生合成の遺伝子情報を元に機能を推測すると、VisE(本文中VirEと記載)の2つのNRPS moduleは、virginiamycin S core構造に2，3番目のアミノ酸(L-threonine, L-2-aminobutyric acid)を取り込むと予想している。
Related Reference
ACC
Q54959
PmId
[9006024] ( , )
comment
BLAST id66%
Streptomyces pristinaespiralis_snbC
Pristinamycin I synthase 2

snbCに強く保存されているHHXXXDGXSW motif(or M box)は、epimerizationのcatalytic roleを担っていると以前の研究で提案されており、epimerization domainに保存されているmotifs(K〜Q)も保存されていた。

保存モチーフ(K〜Q)は、Virg_00090でもsnbC同様保存されていた。しかし、pantetheine attachment consensus motifは、snbCではepimerization activityを持つpeptide synthetasesで保存されている配列であったが、Virg_00090はnonepimerization activity typeであった。

close this sectionPKS/NRPS Module

S1 L-threonine
2 L-aminobutyric acid
C39..338
A541..947
PCP1033..1100
C1117..1417
A1607..2008
PCP2091..2157
E2196..2663

close this sectionSequence

selected fasta
>non-ribosomal peptide synthetase [non ribosomal peptide synthetase for virginiamycin S]
MQFDLVDPSGRLRLPPARRAAAAGSTGGEEMSGAKVASMALTDAQLGVWFAQARDPHSTA
FNTGEYVELTGPLDAGRFTAAVRAAVEATESLRLRFHTRADGEVRQRVVPADESAWELRH
VDVSAEPDPEAAADDLIRRQLAAPMAVDGEGPLFDQVLFTLGPGRHRWFQQVHHLLLDGY
GLRLVARRVADAYNGAGTPAEADDLAALVDAESAYRASRGHARDRAYWLTSWADRPEAPT
LGTGPVARGDAPAAAEGGAVPLRRTVFLPAAVQEGLDALARTAQTGWQVAALAAVALYTR
RLTGAGEAVLGLPVTNRRSSRARRTPAMLTNVPPLRVPARPDTDLTGLVTEVRDRVAEVL
RHQGYPYAELRRELGLLAQDRPLHSIVANIMPFDHGLDFEGIEAQVHPVSTGPVEDLKFS
VYERPGGAGLRIDVEADALRHREEEVAAHLARFTALLHSFATADPALPGGRLDVLAPGEH
VQAAGEAFVPEPSTDEPSTDEPSAHEPSTPDRPTTLPALFEAQAARTPQAVAVVDGHRQL
TYRELDARANRLAHLLTARGAGPERTVALALPRSADLVVALLAVVKTGAAYLPLDPDYPA
ERLASMLADAGPSVIVATAATRVVAPDRTALVLLDDEPQAGLPDTAPRTKHDPRHPAYVI
YTSGSTGRPKGVVVTHHNVVRLFTAAQQHFGFGPSDVWTLFHSYAFDFSVWEIWGPLLHG
GRLVVVPYSTSRSPGAFLDLLAEQRVTVLNQTPSAFYQLIEADRERPRPTALPALRHVVF
GGEALDAPRLEGWYERHGHTASLSNMYGITETTVHVTHTALDGPDGAPGSVGAPLADLRA
HVLDGALRPAPPGVTGELYVAGPGLARGYLGLPALTAERFVADPFAPAGDTGARMYRTGD
LVRRRADGTLEYVGRADHQVKIRGFRIELGEIEAALAALPSVAHAAVTAREDTPGDRRLA
AYAVPADGVPADPAAWRRELAAVLPAHQLPASFTPLDAIPLTVNGKLDRAALPAPGPAEA
ASWATQAAAAGPLEELLCRLFARILGVHEVGPRSDFFALGGHSVIANRLLSAARSELGVE
LTIEDLFARPTPAGLARLARGADTARPRLRPAGDPDGPAVLSPAQQRMWVIREVEGRAPT
YNMPLALRLTGALDRGAMQAALGDLIGRHDTLRTICPAGPDGPLPRVLPLDDVPPWLTET
EVAESDLAQALTSAAREPFDLDTQIPLRAHLFTLAPGEHVLLLVLHHIAGDGWSLRPLFG
DLAAAYDARSKGTAPRPEPLPVTYRDFALWQRELLGDESEPASLGARQLDHWHHALAGLP
DQLQLPYDRPRPPVARHRGGSVPLTIGPALHAQLDGLARTGGATVHMVLQAALAALLTRL
GAGTDVPIGCPTAGRDEEALDGLVGFFVNPVVVRADTSGDPAFAELLTRVRTTALAAYTH
QDVPFDRVVERLQPARSAARHPLFQVVLSYQESEARPRLAGLVVRREPVDFGVAKFDLTF
NLVEHRDDAGAPDGIHGDLEFDLDLFDPATAQAVARRLLALLEAVAAGPELPISRFDLVD
DAERAMLRRWNDTAAPVPDTGLAELFTAQARRTPDATALVAGDTELTYAQLDARAGALAA
RLTALGIGPECPVAVLQERSADLVVSLLAVLRAGGFYVPLNHRNPASRMSQIMTMAGARV
LLTDRAAHERHRCHAWAGQAEVVVVDDPAPASAPAPAAVVPGHPDRLAYVMYTSGSTGTP
KGVAITHRDVAVLAADRCWRTGNQQRVLLHSPYSFDTSQYELWVPLLSGGTVVVAPPGDL
DTAALREALTRGRVTGMWLTSGLFNLLAEESPECFRGVREVWTGGDVVSPAAVTRVLAAS
PDTLVVDGYGPTETTTFSTHHFMRAPWTEETTVPIGSPLDNTTCHVLDQRLRPVPPGVTG
ELYIGGARLARGYLGRPDATAERFVADPSGTPGARMYRTGDLVRRRADGILEFLGRADHQ
VKVRGFRIELGEIESVIGRHPTVAQSAVLVREDRPGDKRVTAYVVPAAAAAADAGELRRH
VAASLPDYMVPAAVVLLDRLPLTPNGKLDRRQLPVPEFAPAGDHRAPAGPREELLAGLFA
GVLGLEQVGTHDSFFDLGGDSIMAIQLVGRARRSGLLLSPAQVFEHKTVAALAGVATAAA
DSGPAPGTAPADDRAWGEVPLTPVMHWLRERGGPVEAFSQSLLVRVPAGLGEQRLATALR
ALADQHDMLRAVLSSDPDSGWRLRIEPPGGGSAEAWARRVDTAGHTDDALRTLITTEAAA
ARSRLDPWSGVMGQAVWFDAGQNRSGRLLLTLHHLVVDGVSWRILLPDLEAAWQAATGDT
APRPAPAGTSFRSWARHLAAEAARPARRAELDLWTGRLAAPALPVTDRPLDPARDTSATA
RSLTLTLPAAATEPLLTTVPATFHAKVDDVLLTAFALAVADWRARRGLGDASAVLLDLEG
HGREPGDSGADLSRTVGWFTSLYPVRLDVGPLDRRDALSGGPAAGQAVKRVKEQLRELPD
GGLGHGLLRHLNAETAPLLAALPTPDIGFNYLGRFKEPEGPDAEWTVTPDAESLGEGTDP
RLPMAHGVELNALTLDGPGGPRLTATWSWPQHLLDEGSVRDLGQGWFRALEALTAHAERP
DAGGHTPSDFSLVSLNQAQIDRLEAMWKVAR
selected fasta
>non-ribosomal peptide synthetase [non ribosomal peptide synthetase for virginiamycin S]
ATGCAATTCGATCTCGTCGACCCCAGTGGTCGGCTGCGCCTGCCCCCGGCCCGTCGGGCC
GCGGCGGCCGGCTCGACAGGAGGGGAAGAGATGAGTGGTGCCAAGGTCGCGTCCATGGCC
CTCACCGATGCACAGCTCGGTGTCTGGTTCGCCCAGGCCAGGGACCCGCACAGCACGGCG
TTCAACACCGGCGAGTACGTCGAGCTGACGGGCCCGCTGGACGCCGGGCGGTTCACCGCT
GCCGTGCGCGCCGCGGTCGAGGCCACCGAGTCCCTGCGCCTGCGCTTCCACACCCGCGCC
GACGGCGAAGTGCGCCAGCGGGTCGTCCCCGCGGACGAGTCGGCCTGGGAGCTGCGCCAC
GTCGACGTCAGCGCCGAACCCGACCCCGAGGCCGCCGCCGACGACCTGATCCGCCGGCAG
CTGGCCGCCCCGATGGCGGTCGACGGCGAAGGACCGCTGTTCGACCAGGTCCTGTTCACC
CTCGGCCCCGGCCGCCACCGCTGGTTCCAGCAAGTCCACCACCTGCTGCTCGACGGCTAC
GGGCTGCGCCTGGTGGCCCGGCGCGTCGCCGACGCCTACAACGGCGCGGGCACGCCGGCC
GAGGCCGACGACCTCGCCGCCCTGGTCGACGCCGAGAGTGCTTACCGTGCTTCGCGCGGC
CACGCCCGCGACCGCGCGTACTGGCTCACCTCCTGGGCTGACCGCCCGGAGGCACCCACC
CTGGGCACCGGTCCCGTCGCCCGGGGCGACGCCCCGGCGGCTGCCGAGGGCGGTGCCGTG
CCGCTGCGCCGCACGGTGTTCCTGCCCGCGGCCGTCCAGGAGGGCCTCGACGCGCTCGCC
CGCACCGCGCAGACCGGCTGGCAGGTGGCCGCTCTGGCCGCCGTCGCCCTCTACACCCGG
CGCCTGACCGGCGCCGGGGAGGCCGTACTGGGGCTCCCGGTCACCAACCGGCGCTCGAGC
AGAGCCCGCCGCACCCCCGCCATGCTCACCAACGTGCCGCCGCTGCGGGTGCCCGCCCGG
CCCGACACCGACCTCACCGGCCTGGTCACCGAGGTCCGCGACCGGGTCGCCGAGGTGCTG
CGGCACCAGGGCTACCCGTACGCCGAACTCCGCCGCGAACTGGGGCTGCTGGCGCAGGAC
CGCCCCCTGCACTCGATCGTCGCCAACATCATGCCGTTCGACCACGGCCTGGACTTCGAA
GGCATCGAGGCGCAGGTCCACCCGGTGTCGACCGGCCCCGTCGAGGACCTCAAGTTCTCG
GTGTACGAGCGTCCCGGCGGCGCCGGCCTGCGGATCGATGTCGAAGCCGACGCCCTGCGC
CACCGTGAGGAGGAGGTCGCCGCCCACCTGGCCCGTTTCACCGCCCTGCTGCATTCCTTC
GCCACCGCCGACCCCGCGCTGCCCGGCGGCCGGCTGGACGTCCTCGCCCCGGGCGAGCAC
GTGCAGGCCGCCGGCGAGGCGTTCGTGCCCGAGCCGTCCACCGACGAGCCGTCCACCGAC
GAGCCGTCCGCCCACGAGCCGTCCACCCCGGACCGTCCCACCACGCTGCCCGCCCTGTTC
GAGGCGCAGGCCGCCCGAACCCCGCAGGCCGTCGCCGTCGTCGACGGCCACCGGCAGCTC
ACCTACCGCGAACTCGACGCCAGGGCCAACCGCCTCGCCCACCTGCTCACGGCCCGCGGC
GCCGGCCCCGAGCGTACCGTCGCGCTCGCCCTGCCCCGCTCCGCCGACCTGGTCGTCGCC
CTGCTCGCGGTGGTCAAGACCGGCGCCGCCTACCTGCCGTTGGACCCGGACTACCCGGCC
GAGCGGCTGGCGTCCATGCTGGCCGACGCCGGCCCGTCCGTGATCGTCGCGACGGCCGCC
ACCCGGGTCGTCGCCCCCGACCGCACGGCCCTGGTCCTCCTTGACGACGAGCCGCAGGCC
GGCCTGCCCGACACCGCCCCGCGCACGAAGCACGACCCCCGCCACCCGGCCTACGTCATC
TACACCTCCGGCTCCACCGGCCGGCCCAAGGGCGTGGTCGTCACCCACCACAACGTGGTG
CGGCTGTTCACCGCCGCACAGCAGCACTTCGGCTTCGGCCCGTCGGACGTGTGGACGCTG
TTCCATTCCTACGCCTTCGACTTCTCCGTGTGGGAGATCTGGGGCCCGCTGCTGCACGGC
GGCCGCCTGGTCGTCGTCCCGTACTCCACCAGCCGTTCCCCCGGAGCCTTCCTCGACCTG
CTGGCCGAGCAGCGGGTCACGGTGCTCAACCAGACACCGTCCGCGTTCTACCAGCTGATC
GAGGCCGACCGGGAGCGGCCGCGGCCCACTGCCCTGCCCGCCCTGCGGCACGTCGTCTTC
GGCGGTGAGGCCCTGGATGCGCCCCGGCTGGAGGGCTGGTACGAGCGCCACGGCCACACT
GCGTCGCTGTCCAACATGTACGGGATCACCGAGACCACCGTGCACGTCACCCACACCGCC
CTCGACGGACCGGACGGCGCCCCTGGCTCCGTGGGCGCACCCCTCGCCGACCTCCGCGCC
CACGTGCTGGACGGAGCGCTACGCCCCGCGCCGCCCGGCGTCACCGGCGAGCTGTACGTC
GCGGGCCCCGGCCTCGCCCGCGGCTACCTCGGACTCCCCGCCCTCACCGCCGAGCGGTTC
GTCGCCGACCCCTTCGCGCCCGCCGGCGACACCGGCGCACGCATGTACCGCACCGGCGAC
CTGGTCCGCCGCCGCGCCGACGGCACCCTGGAGTACGTCGGCCGCGCCGACCACCAGGTG
AAGATCCGCGGGTTCCGCATCGAACTCGGCGAGATCGAGGCGGCGCTCGCCGCACTGCCG
TCGGTGGCCCACGCCGCGGTGACCGCCCGCGAGGACACCCCGGGCGACCGGCGGCTCGCG
GCGTACGCCGTCCCGGCCGACGGCGTCCCGGCCGACCCGGCCGCCTGGCGCCGCGAGCTC
GCCGCCGTACTGCCCGCCCACCAGCTGCCGGCCTCGTTCACCCCGCTCGACGCGATCCCG
CTCACCGTCAACGGCAAGCTCGACCGTGCCGCCCTGCCCGCCCCCGGCCCCGCCGAGGCC
GCGTCGTGGGCCACGCAGGCAGCCGCCGCCGGGCCGCTGGAAGAACTGCTGTGCCGCCTG
TTCGCACGCATCCTGGGCGTGCACGAAGTCGGACCGCGGAGCGACTTCTTCGCACTCGGC
GGGCACTCGGTGATCGCCAACCGGCTGCTGTCCGCAGCCCGCAGCGAGCTCGGCGTCGAG
CTGACCATCGAAGACCTCTTCGCCCGGCCCACCCCCGCCGGCCTCGCCCGGCTCGCCCGG
GGCGCCGACACCGCCCGCCCGCGACTGCGGCCCGCCGGCGACCCGGACGGACCGGCCGTC
CTCTCGCCCGCCCAGCAGCGCATGTGGGTGATACGCGAGGTCGAGGGCCGCGCCCCGACG
TACAACATGCCGCTTGCGTTGCGGCTCACCGGCGCACTGGACCGCGGCGCGATGCAAGCC
GCCCTCGGCGACCTGATCGGCCGCCACGACACCCTGCGCACCATCTGCCCGGCCGGACCG
GACGGCCCGCTGCCCCGGGTGCTGCCGCTCGACGACGTCCCGCCGTGGCTGACCGAGACC
GAGGTGGCCGAATCGGATCTGGCGCAGGCCCTCACCTCGGCCGCGCGCGAACCGTTCGAC
CTCGACACGCAGATCCCGCTGCGCGCCCACCTGTTCACCCTGGCCCCCGGCGAGCACGTC
CTGCTGCTGGTTCTGCACCACATCGCCGGGGACGGCTGGTCGCTGCGCCCGCTCTTCGGC
GACCTCGCCGCCGCCTACGACGCCCGCTCCAAGGGCACGGCACCCCGCCCGGAGCCGCTG
CCCGTCACCTACCGGGACTTCGCGCTCTGGCAGCGCGAACTGCTCGGCGACGAGAGCGAG
CCGGCCTCCCTGGGCGCCCGCCAGCTCGACCACTGGCACCACGCGCTGGCCGGCCTGCCC
GACCAGCTCCAGCTCCCCTACGACCGCCCCCGCCCGCCGGTCGCCCGGCACCGCGGCGGC
TCGGTGCCGCTGACCATCGGCCCCGCGCTGCACGCGCAGCTCGACGGGCTCGCCCGCACC
GGCGGCGCCACCGTCCACATGGTCCTCCAAGCCGCCCTGGCCGCACTGCTCACCAGGCTC
GGCGCCGGCACCGACGTCCCCATCGGCTGCCCCACCGCCGGCCGGGACGAGGAGGCCCTC
GACGGGCTCGTCGGCTTCTTCGTCAACCCCGTCGTGGTCCGCGCCGACACCTCCGGCGAC
CCGGCCTTCGCCGAACTCCTCACTCGCGTACGCACCACCGCGCTGGCCGCCTACACCCAC
CAGGACGTGCCCTTCGACCGCGTGGTGGAGCGCCTTCAGCCGGCCCGCTCCGCCGCCCGG
CACCCGCTTTTCCAGGTGGTGCTCTCGTACCAGGAGTCCGAGGCCCGGCCGCGGCTGGCC
GGACTCGTCGTGCGTCGCGAACCGGTCGACTTCGGCGTCGCCAAGTTCGACCTCACCTTC
AACCTGGTCGAGCACCGCGACGACGCGGGTGCCCCCGACGGCATCCACGGCGACCTCGAG
TTCGACCTCGACCTGTTCGACCCCGCGACCGCGCAGGCCGTCGCCCGCCGGCTGCTGGCC
CTGCTGGAGGCCGTCGCCGCCGGCCCCGAACTGCCGATCAGCCGGTTCGACCTGGTCGAT
GACGCCGAGCGGGCCATGCTGCGCCGGTGGAACGACACCGCCGCCCCGGTCCCGGACACC
GGTCTCGCCGAGCTGTTCACCGCCCAGGCGCGCCGCACCCCCGACGCGACGGCCCTGGTG
GCCGGCGACACCGAGCTGACCTACGCCCAGCTCGACGCCCGGGCCGGCGCCCTCGCCGCC
CGGCTCACCGCCCTGGGCATCGGCCCGGAGTGCCCCGTCGCCGTGCTCCAGGAACGTTCC
GCGGACCTGGTGGTGTCCCTCTTGGCCGTACTGCGGGCAGGCGGCTTCTACGTCCCGCTC
AACCACCGGAACCCGGCCTCCCGGATGAGTCAGATCATGACCATGGCCGGGGCCCGGGTC
CTGCTGACCGACCGGGCCGCACACGAAAGGCACCGCTGCCACGCATGGGCCGGGCAGGCC
GAGGTGGTCGTCGTGGACGATCCCGCGCCCGCGTCGGCGCCCGCCCCCGCCGCGGTCGTC
CCGGGCCACCCCGACCGGCTGGCGTACGTGATGTACACCTCCGGCTCCACCGGCACGCCC
AAGGGCGTCGCCATCACCCACCGGGACGTCGCCGTGCTCGCCGCCGACCGCTGCTGGCGC
ACCGGCAACCAGCAGCGGGTACTGCTGCACTCCCCGTACTCGTTCGACACCTCCCAGTAC
GAGCTGTGGGTGCCGCTGCTGTCCGGCGGGACCGTCGTGGTCGCCCCGCCCGGGGACCTC
GACACCGCCGCTCTCCGCGAGGCCCTCACGCGCGGACGGGTCACCGGCATGTGGCTCACC
TCCGGGCTGTTCAACCTGCTCGCCGAGGAGAGCCCCGAATGCTTCCGCGGCGTGCGCGAG
GTGTGGACCGGAGGTGACGTGGTCTCGCCCGCTGCCGTCACCCGGGTCCTGGCCGCCTCC
CCGGACACGCTGGTCGTCGACGGCTACGGCCCGACCGAGACCACGACCTTCTCCACCCAC
CACTTCATGCGCGCCCCGTGGACCGAGGAGACCACCGTCCCGATCGGCAGCCCCCTCGAC
AACACCACCTGCCACGTCCTCGACCAGCGGCTTCGCCCCGTGCCGCCGGGAGTCACCGGC
GAGCTCTACATCGGCGGCGCCCGTCTCGCCCGCGGCTACCTCGGCCGCCCCGACGCCACC
GCCGAACGGTTCGTGGCCGACCCGTCCGGTACGCCCGGCGCACGCATGTACCGCACCGGC
GACCTGGTGCGCCGCCGCGCCGACGGCATCCTGGAGTTCCTCGGCCGCGCCGACCACCAG
GTCAAGGTCCGCGGCTTCCGCATCGAACTCGGCGAGATCGAGTCCGTCATCGGCCGCCAC
CCCACCGTCGCGCAGAGCGCCGTACTCGTACGCGAGGACCGCCCCGGCGACAAGCGGGTC
ACCGCCTACGTGGTGCCCGCCGCGGCAGCCGCGGCCGACGCCGGCGAACTGCGCCGGCAC
GTCGCCGCGTCCCTGCCCGACTACATGGTCCCGGCCGCCGTCGTGCTGCTGGACCGGCTG
CCCCTGACCCCCAACGGCAAGCTCGACCGCCGGCAGCTGCCCGTCCCCGAGTTCGCCCCC
GCAGGCGACCACCGGGCCCCTGCCGGCCCCCGCGAGGAACTGCTCGCCGGCCTGTTCGCC
GGCGTCCTCGGCCTGGAGCAGGTCGGTACCCACGACAGCTTCTTCGACCTGGGCGGCGAC
AGCATCATGGCGATCCAGCTGGTCGGCCGCGCCCGCCGGTCCGGCCTGCTGCTCTCGCCC
GCCCAGGTCTTCGAGCACAAGACCGTCGCCGCCCTGGCCGGCGTCGCCACCGCCGCGGCC
GACAGCGGACCGGCCCCCGGCACCGCACCGGCGGACGACCGGGCCTGGGGCGAGGTACCG
CTCACCCCGGTCATGCACTGGCTGCGCGAACGCGGCGGCCCCGTCGAGGCGTTCAGCCAG
TCCCTGCTCGTCCGGGTGCCGGCCGGGCTCGGCGAGCAGCGCCTGGCCACCGCCCTGCGC
GCCCTCGCCGACCAGCACGACATGCTGCGCGCGGTCCTGTCCTCCGACCCGGACAGCGGT
TGGCGGCTGCGCATCGAACCGCCCGGCGGCGGCAGCGCCGAAGCCTGGGCCCGCAGGGTC
GACACCGCCGGCCACACCGACGACGCACTGCGCACCCTGATCACCACCGAGGCGGCCGCC
GCACGCAGCCGGCTCGACCCCTGGTCGGGCGTGATGGGACAGGCCGTCTGGTTCGACGCC
GGCCAGAACCGGTCCGGACGCCTGCTGCTCACCCTCCACCACCTGGTGGTCGACGGCGTG
TCCTGGCGCATCCTGCTGCCCGACCTGGAGGCCGCCTGGCAGGCAGCGACCGGGGACACC
GCCCCGCGCCCGGCGCCCGCCGGCACCTCCTTCCGCAGCTGGGCCCGGCACCTGGCCGCC
GAGGCCGCCCGTCCCGCCCGCCGCGCCGAACTCGACCTGTGGACCGGCCGCCTGGCCGCG
CCCGCCCTACCCGTCACCGACCGGCCGCTCGACCCCGCCCGGGACACCTCCGCCACCGCA
CGCAGCCTCACCCTGACCCTCCCGGCGGCCGCCACCGAACCCCTGCTCACCACCGTGCCC
GCCACGTTCCACGCCAAGGTCGACGACGTCCTGCTCACCGCCTTCGCGCTGGCCGTCGCC
GATTGGCGGGCCCGCCGCGGTCTCGGCGACGCGTCAGCCGTCCTGCTCGACCTGGAGGGC
CACGGCCGCGAACCGGGCGACAGCGGCGCCGATCTGTCCCGTACCGTCGGCTGGTTCACC
AGCCTCTACCCCGTACGCCTCGACGTCGGCCCGCTCGATCGCCGCGACGCCCTGTCCGGC
GGCCCCGCGGCCGGACAGGCTGTCAAACGGGTCAAGGAACAGCTGCGGGAACTTCCCGAC
GGCGGCCTCGGCCATGGCCTCCTGCGCCACCTGAACGCCGAGACCGCGCCGCTCCTGGCC
GCACTGCCGACGCCCGACATCGGCTTCAACTACCTGGGCCGCTTCAAGGAGCCGGAAGGG
CCGGACGCCGAATGGACCGTCACCCCCGACGCCGAATCCCTCGGTGAGGGCACCGACCCC
CGACTGCCGATGGCCCACGGCGTCGAGCTGAACGCCCTCACTCTGGACGGCCCGGGCGGC
CCCCGCCTGACCGCCACCTGGAGTTGGCCGCAGCACCTGCTCGACGAGGGCTCCGTACGC
GACCTCGGACAGGGCTGGTTCCGCGCCCTCGAAGCCCTCACCGCCCACGCCGAGCGCCCC
GACGCCGGCGGGCACACCCCGTCCGACTTCTCCCTGGTCTCCCTGAACCAGGCCCAGATC
GACCGACTCGAAGCCATGTGGAAGGTTGCCCGATGA
[1] C39..338
[1] A541..947
[1] L-threonine707..815
[1] PCP1033..1100
[2] C1117..1417
[2] A1607..2008
[2] L-aminobutyric acid1776..1877
[2] PCP2091..2157
[2] E2196..2663
[1] C115..1014
[1] A1621..2841
[1] L-threonine2119..2445
[1] PCP3097..3300
[2] C3349..4251
[2] A4819..6024
[2] L-aminobutyric acid5326..5631
[2] PCP6271..6471
[2] E6586..7989

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR000873 AMP-dependent synthetase/ligase (Domain)
[541-947] 5.20000000000001e-126 PF00501 [1607-2008] 1.99999999999999e-111 PF00501
PF00501   AMP-binding
IPR001242 Condensation domain (Domain)
[39-338] 8.20000000000006e-40 PF00668 [1117-1417] 1.80000000000002e-62 PF00668 [2196-2489] 8.00000000000001e-37 PF00668
PF00668   Condensation
IPR006162 Phosphopantetheine attachment site (PTM)
[1058-1073] PS00012 [2116-2131] PS00012
PS00012   PHOSPHOPANTETHEINE
IPR009081 Acyl carrier protein-like (Domain)
[1026-1101] 9.40000000000003e-48 G3DSA:1.10.1200.10 [2083-2158] 9.40000000000003e-48 G3DSA:1.10.1200.10
G3DSA:1.10.1200.10   ACP_like
[1036-1098] 7e-12 PF00550 [2095-2153] 1.3e-11 PF00550
PF00550   PP-binding
[1033-1100] PS50075 [2091-2157] PS50075
PS50075   ACP_DOMAIN
[1026-1133] 7.60000011115812e-20 SSF47336 [2084-2158] 4.40000933643891e-18 SSF47336
SSF47336   ACP_like
IPR010060 Non-ribosomal peptide synthase (Domain)
[2504-2663] 5.49999999999995e-44 TIGR01720
TIGR01720   NRPS-para261
IPR010071 Amino acid adenylation domain (Domain)
[541-947] TIGR01733 [1607-2008] 4.10000000000004e-130 TIGR01733
TIGR01733   AA-adenyl-dom
IPR020845 AMP-binding, conserved site (Conserved_site)
[659-670] PS00455 [1730-1741] PS00455
PS00455   AMP_BINDING
SignalP
[1-22] 0.504 Signal
Bacteria, Gram-positive   
TMHMM No significant hit
Virg_00080 Virg_00080   Virg_00100 Virg_00100
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