Oxtet_00150 : CDS information

Location

Organism	Streptomyces rimosus
Strain	ATCC 10970 (=NBRC 12907)
Entry name	Oxytetracycline
Contig	DQ143963
Start / Stop / Direction	15,734 / 16,795 / + [in whole cluster] 15,734 / 16,795 / + [in contig]
Location	15734..16795 [in whole cluster] 15734..16795 [in contig]
Type	CDS
Length	1,062 bp (353 aa)

Annotation

Category	5.4 hypothetical protein
Product	hypothetical protein
Product (GenBank)	OxyO
Gene	oxyO otcD5
Gene (GenBank)	oxyO
EC number
Keyword
Note
Note (GenBank)
Reference	ACC Q3S8Q1 PmId [16597959] Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase. (Appl Environ Microbiol. , 2006) comment oxytetracycline gene clusterのシークエンス、配列解析。 resistance genes otrAとotrBの間に全21genesを同定。わかりやすくするため、gene namesがotc → oxyに変更され、振り直されている。 oxyO (otcD5): Unknown 詳細記載なし。

Sequence

>hypothetical protein [OxyO]
MRNRRSQQLHRVVRRASRAGNGPPPAGSVPPRPELGWARLIELTSVLLASVVAVLSLWFS
NRQVGNQLRIAQGELSTTREGQITERYTAAVGQLGEDSVDVRLGGIYALQRNMEDLPRDH
PTIADVLAAYIRTHAGTPPKGGKRVPPDVLAALDVISGRNSAHDGSFVPDLRSTHLPGVE
LGWDRSSPVAADHKRAQLRGAILRDCDLRDARLSGADLRGARLARADLADADLREADLRE
ATPARANLRDADLSDANVRKADLRFADLRGVDLWGTDLRGAVLYRAKLAGLELSEAHLDG
ADLRGADLTDAAVARSQVLASRIDAETRLPPDIARDPEVRARIAQAEAEDDGF

>hypothetical protein [OxyO]
ATGCGAAACCGGCGGAGTCAGCAGTTGCACCGCGTGGTCCGGCGCGCTTCCCGGGCCGGG
AACGGCCCGCCACCGGCCGGCAGCGTCCCTCCGCGTCCGGAGCTGGGCTGGGCCCGTCTG
ATCGAGCTGACTTCGGTACTGCTCGCCTCGGTCGTCGCCGTGCTGAGCCTCTGGTTCTCC
AACCGCCAGGTGGGCAACCAGTTGCGGATCGCCCAGGGCGAGCTGAGCACCACCAGGGAA
GGTCAGATCACCGAGCGGTACACCGCGGCCGTGGGCCAGCTGGGCGAGGATTCGGTGGAC
GTGCGCCTGGGCGGCATCTACGCCCTGCAGCGCAACATGGAGGACCTCCCCCGCGACCAC
CCCACCATCGCCGACGTCCTGGCCGCCTATATCCGCACCCACGCCGGCACCCCGCCGAAA
GGCGGCAAACGGGTGCCACCCGATGTCCTGGCCGCGCTCGACGTGATCAGCGGCCGGAAC
TCCGCCCATGACGGCTCCTTCGTTCCCGACCTCCGCTCCACCCACCTGCCCGGCGTCGAA
CTGGGGTGGGACCGTTCGTCTCCCGTCGCCGCCGACCACAAGCGGGCCCAGTTGCGCGGA
GCGATCCTCCGTGACTGCGACCTGAGGGACGCGCGTCTGAGCGGCGCGGACCTGCGAGGC
GCGAGGCTCGCACGCGCCGATCTGGCCGACGCGGATCTGCGCGAGGCGGACCTCCGGGAA
GCCACTCCGGCGCGGGCGAACCTGCGCGACGCGGACTTGTCCGACGCCAACGTGCGCAAG
GCGGACCTGAGGTTCGCGGATCTTCGCGGCGTGGACCTGTGGGGCACCGATCTGCGCGGC
GCGGTCCTGTACCGGGCGAAACTGGCCGGCCTGGAGCTCAGCGAGGCGCACCTGGACGGA
GCCGACCTCCGCGGTGCTGATCTCACGGACGCGGCGGTGGCACGGAGCCAGGTCCTCGCG
AGCCGCATCGACGCGGAGACCAGGCTCCCACCGGACATCGCCCGCGATCCGGAGGTGCGG
GCCCGGATCGCTCAGGCCGAGGCGGAGGACGATGGTTTCTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR001646 Pentapeptide repeat (Repeat) PF00805 Pentapeptide
SignalP	No significant hit
TMHMM	No significant hit

Oxtet_00140 Oxtet_00160