Madu_00150 : CDS information

Location

Organism	Actinomadura madurae
Strain	ATCC 39144
Entry name	Maduropeptin
Contig	AY271660
Start / Stop / Direction	24,329 / 23,145 / - [in whole cluster] 24,329 / 23,145 / - [in contig]
Location	complement(23145..24329) [in whole cluster] complement(23145..24329) [in contig]
Type	CDS
Length	1,185 bp (394 aa)

Annotation

Category	5.1 general function
Product	putative oxidoreductase
Product (GenBank)	oxidoreductase
Gene
Gene (GenBank)	mdpD2
EC number
Keyword
Note
Note (GenBank)
Reference	ACC B0BLM4 PmId [17918933] Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis. (J Am Chem Soc. , 2007) comment Maduropeptin生合成遺伝子クラスターの報告 mdpD2: Oxidoreductase 本文中特に記述なし。
Related Reference	ACC Q6PV90 PmId [15357313] Molecular cloning and identification of a novel oxygenase gene specifically induced during the growth of Rhodococcus sp. strain T104 on limonene. (J Microbiol. , 2004) comment Rhodococcus sp. T104 Indole oxygenase limonene degradationとindigo-producing abilityとの関連を見いだし、これに関与する8,842-bp genomic DNA regionの配列解析を行ったところ、そのうちのひとつがindoleからindigo (a blue pigment)を生成する反応に関与するindole oxygenaseであった。

Sequence

>putative oxidoreductase [oxidoreductase]
MVSTSAVPTRKELVARAAELAPVLRSNSAWSEKNRRLHDESVQALADAGLFRMRMPARYG
GYECDTRTLVEVAAELGRADGSAAWVASVYWIPGWMTCLFPDEVQDEVFSTPDVRVCGTL
SPSAIAKPVDGGVVVTGKWGFISGAHHAEWQEIIAILTPEDGEPYPVMGLVPLSELLVVD
DWNTSGLRGTGSISTVARDLFVPQERVLPLPAVLQGQPASARNAGTPIYRVPLLPVASAS
SVGAVLGMAYAARDAFHKRLPGRKITYTGYESQRDATITHLQIAEATMKTDEAEFHAYRL
ADLVDAKAAEGTPWKLEERAQVRADLGAVCRLAKEAVDVLASASGGSSIYEDVPIQRILR
DVQAVNQHALMNPNTNTELYGRVLCGLEPNTLYI

>putative oxidoreductase [oxidoreductase]
ATGGTGTCGACCAGTGCGGTCCCCACCCGGAAAGAACTCGTCGCGCGGGCGGCCGAATTG
GCGCCGGTCCTGCGCTCCAACAGTGCCTGGTCGGAGAAGAACCGGCGGTTGCACGACGAG
TCGGTCCAGGCGCTCGCCGACGCGGGACTGTTCAGAATGCGCATGCCCGCCCGGTACGGG
GGCTACGAGTGCGACACCCGGACGCTGGTCGAGGTGGCCGCCGAACTGGGGCGCGCCGAC
GGCTCCGCCGCGTGGGTGGCGTCGGTGTACTGGATCCCCGGGTGGATGACGTGCCTGTTC
CCCGACGAGGTCCAGGACGAGGTGTTCTCGACCCCCGACGTGCGGGTGTGCGGAACGCTG
AGCCCGAGCGCGATCGCCAAGCCGGTGGACGGCGGCGTCGTCGTCACCGGCAAGTGGGGC
TTCATCAGCGGCGCCCACCACGCCGAGTGGCAGGAGATCATCGCGATCCTGACGCCCGAG
GACGGCGAGCCGTACCCGGTGATGGGGCTGGTCCCCCTGTCGGAGCTGCTGGTCGTGGAC
GACTGGAACACCTCGGGGCTGCGCGGCACGGGCAGCATCAGCACGGTCGCCCGGGACCTG
TTCGTCCCGCAGGAGCGGGTCCTGCCGCTGCCGGCCGTCCTGCAGGGGCAGCCGGCGTCC
GCGCGCAACGCCGGGACGCCGATCTACCGGGTGCCGCTGCTGCCCGTCGCGTCCGCCTCG
TCGGTCGGTGCCGTGCTGGGGATGGCGTACGCGGCCCGCGACGCCTTCCACAAGCGCCTT
CCCGGCCGCAAGATCACCTACACCGGGTACGAGAGCCAGCGCGACGCGACGATCACGCAC
CTGCAGATCGCCGAGGCGACGATGAAGACCGACGAGGCGGAGTTCCACGCCTACCGGCTC
GCGGACCTGGTCGACGCCAAGGCCGCCGAGGGCACGCCCTGGAAGCTGGAGGAACGCGCG
CAGGTCCGGGCGGACCTCGGCGCCGTCTGCCGCCTCGCCAAGGAGGCCGTGGACGTCCTG
GCCTCCGCCAGCGGCGGATCGTCGATCTACGAGGACGTGCCGATCCAGCGGATCCTCCGC
GACGTCCAGGCCGTCAACCAGCACGCCCTGATGAACCCGAACACCAACACCGAGCTCTAC
GGCCGCGTGCTGTGCGGCCTCGAGCCCAACACGCTCTACATCTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain (Domain) G3DSA:2.40.110.10 Acyl_CoA_DH/ox_M IPR006092 Acyl-CoA dehydrogenase, N-terminal (Domain) PF02771 Acyl-CoA_dh_N IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal (Domain) G3DSA:1.20.140.10 AcylCoA_DH_1/2_C SSF47203 AcylCoADH_C_like IPR009100 Acyl-CoA dehydrogenase/oxidase (Domain) SSF56645 AcylCoA_dehyd_NM IPR013107 Acyl-CoA dehydrogenase, type 2, C-terminal (Domain) PF08028 Acyl-CoA_dh_2 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal (Domain) G3DSA:1.10.540.10 AcylCoA_DH/ox_N
SignalP	No significant hit
TMHMM	No significant hit

Madu_00140 Madu_00160