Calm_00300 : CDS information

Location

Organism	Micromonospora echinospora
Strain	NRRL 15839
Entry name	Calicheamicin
Contig	AF497482
Start / Stop / Direction	34,553 / 33,669 / - [in whole cluster] 34,553 / 33,669 / - [in contig]
Location	complement(33669..34553) [in whole cluster] complement(33669..34553) [in contig]
Type	CDS
Length	885 bp (294 aa)

Annotation

Category	5.1 general function
Product	putative methyltransferase
Product (GenBank)	CalE5
Gene
Gene (GenBank)	calE5
EC number
Keyword
Note
Note (GenBank)
Reference	ACC Q8KNG7 PmId [12183629] The calicheamicin gene cluster and its iterative type I enediyne PKS. (Science. , 2002) comment calicheamicin生合成遺伝子クラスターの報告 polyketide construction or modificationに関与するORFとしている。機能解析はされていない。
Family/Domain	FD IPR013216 comment [IPR013216] Methyltransferase type 11 (Domain)

Sequence

>putative methyltransferase [CalE5]
MAFKAEQRDTWNAVSAGWDYWQDRYERAAAPVTDWLLRAAGLRPGHRVLDVGCGTGEPSV
SAGRLVAPTGRVLGIDLSPEMVDRARRCAAGLGHPIDFAESDVEALDLPAHSFDAVLSRW
GLMFAVDRQRTLTDLHRLLAPGGVLAAAVWGPPEANPMTALGFRTLAAGLPVPPPGRPGP
FSMSDAGRVRADLLAAGFTDVGTESVGYTRDVTPPGVLATVRRQLGADAERAGWDRLAEA
AAAFADADGLLTLPGSALCLRARRPADTSAAPADGGRPEAAGSGPPGAGPGRAG

>putative methyltransferase [CalE5]
GTGGCCTTCAAGGCCGAGCAACGTGACACCTGGAACGCGGTCAGCGCCGGGTGGGACTAC
TGGCAGGACCGCTACGAGCGGGCCGCGGCGCCGGTGACCGACTGGCTGCTGCGCGCCGCC
GGGCTCCGCCCCGGTCACCGGGTGCTCGACGTCGGCTGCGGCACCGGCGAGCCGTCGGTC
AGCGCCGGCCGGCTGGTCGCCCCGACCGGCCGGGTGCTCGGCATCGACCTCTCCCCGGAG
ATGGTCGACCGGGCCCGCCGCTGCGCCGCCGGCCTCGGCCACCCCATCGACTTCGCCGAG
TCCGACGTGGAGGCCCTCGATTTGCCGGCGCACTCCTTCGACGCGGTGCTCAGCCGGTGG
GGGCTGATGTTCGCGGTGGACCGCCAGCGCACCCTCACGGACCTGCACCGCCTCCTGGCG
CCCGGCGGCGTGCTGGCCGCCGCCGTCTGGGGGCCGCCGGAGGCGAACCCGATGACCGCG
CTGGGCTTCCGGACGCTGGCCGCGGGCCTGCCGGTCCCCCCGCCGGGCCGCCCCGGCCCG
TTCAGCATGTCCGACGCCGGCCGCGTCCGCGCCGACCTGCTCGCCGCCGGCTTCACGGAC
GTCGGCACCGAGTCCGTCGGGTACACCCGGGACGTGACGCCGCCCGGTGTCCTCGCCACG
GTGCGGCGGCAGCTCGGCGCCGACGCGGAGCGGGCGGGCTGGGACCGGCTCGCCGAGGCC
GCCGCCGCCTTCGCCGACGCGGACGGCCTGCTCACCCTGCCCGGCTCGGCGCTCTGCCTG
CGCGCGCGCCGGCCCGCCGACACCTCCGCGGCGCCGGCCGACGGTGGCCGACCCGAGGCG
GCCGGATCCGGCCCGCCGGGGGCCGGGCCGGGGAGGGCCGGATGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR013216 Methyltransferase type 11 (Domain) PF08241 Methyltransf_11
SignalP	No significant hit
TMHMM	No significant hit

Calm_00290 Calm_00310