Gelda2_00240 : CDS information

Location

Organism	Streptomyces geldanamycininus
Strain	NRRL 3602 (=NBRC 14620)
Entry name	Geldanamycin
Contig	AY952143
Start / Stop / Direction	1,252 / 428 / - [in whole cluster] 1,252 / 428 / - [in contig]
Location	complement(428..1252) [in whole cluster] complement(428..1252) [in contig]
Type	CDS
Length	825 bp (274 aa)

Annotation

Category	4.1 transcriptional regulator
Product	putative MerR family transcriptional regulator
Product (GenBank)	putative transcriptional regulator
Gene
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)	ORF1; similar to Streptomyces hygroscopicus GdnT encoded by GenBank Accession Number AF521894
Reference	ACC Q49BC5 comment gdm PKS clusterから30kb以上離れたところにあるAHBA関連clusterに含まれるORF。 UniProtで登録されている[PMID:16085885]で同定されたという6ORFsにこのORFは含まれない。
Related Reference	ACC Q848A6 NITE Gelda_00220 comment Blast id91%, 1e-142 Streptomyces hygroscopicus 17997_gdnT geldanamycin生合成に関連するAHBA生合成clusterに隣接するORF。関連する論文なし。
Family/Domain	FD IPR000551 comment [IPR000551] Transcription regulator HTH, MerR (Domain)

Sequence

>putative MerR family transcriptional regulator [putative transcriptional regulator]
MFTIGDFARHGRVSVRMLRHYDATGLLRPAHVDPATGYRYYAAAQLSRLNRVIALKELGF
TLQQVRDIVDEKAGTEELRGMLRLRRAELEATVAAVAARLVQVEARLRSIESEGHMPTND
VVIKEIRAVRVAELTATATGFDPRDIGPVITPLYDELFRRLDAAGITPTGPGVAYYEDAP
EGGGAITVHAAVQVSAPLRDGEDLRILDLPPVDRAATIVHRGPMDAVVPTAQALAHWIDG
NGYRSSGYPREVNLECPENREEWVTELQTPVVEV

>putative MerR family transcriptional regulator [putative transcriptional regulator]
ATGTTCACCATCGGAGACTTCGCCCGGCACGGCCGCGTATCGGTCCGGATGCTGCGCCAC
TACGACGCCACCGGACTGCTGCGCCCGGCCCATGTCGACCCCGCCACCGGCTACCGCTAC
TACGCGGCCGCCCAGCTCAGCCGCCTGAACCGGGTCATCGCGCTCAAAGAGCTCGGCTTC
ACCCTCCAGCAGGTGCGGGACATCGTGGACGAGAAGGCCGGCACCGAGGAACTGCGCGGC
ATGCTGCGGTTGCGGCGGGCCGAGCTGGAAGCCACCGTGGCCGCCGTGGCGGCACGGCTG
GTGCAGGTCGAGGCGAGGCTCCGGTCGATCGAAAGCGAAGGACACATGCCCACGAACGAC
GTCGTCATCAAGGAGATCCGGGCAGTGCGGGTGGCGGAGCTCACCGCGACCGCCACCGGC
TTCGACCCCCGGGACATCGGCCCGGTCATCACACCCCTCTACGACGAGCTGTTCCGGCGC
CTCGATGCGGCGGGCATCACCCCGACGGGCCCCGGTGTCGCGTACTACGAGGACGCCCCG
GAAGGCGGCGGCGCCATCACCGTCCACGCCGCCGTCCAGGTCTCCGCCCCGCTCCGGGAC
GGTGAGGACCTCCGGATCCTCGATCTGCCGCCCGTCGACCGGGCCGCGACCATCGTCCAC
CGCGGCCCGATGGACGCCGTGGTGCCCACGGCCCAGGCCCTGGCCCATTGGATCGACGGC
AACGGCTACCGGTCGTCCGGCTACCCCCGGGAGGTCAACCTGGAGTGTCCGGAGAACCGC
GAGGAGTGGGTCACGGAACTCCAGACACCGGTGGTCGAGGTCTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR000551 Transcription regulator HTH, MerR (Domain) PS50937 HTH_MERR_2 SM00422 HTH_MERR IPR009061 DNA binding domain, putative (Domain) SSF46955 Putativ_DNA_bind IPR010499 Bacterial transcription activator, effector binding (Domain) SM00871 AraC_E_bind PF06445 GyrI-like IPR011256 Regulatory factor, effector, bacterial (Domain) SSF55136 Bac_reg_effector
SignalP	No significant hit
TMHMM	No significant hit

first Gelda2_00250