Lydi_00240 Lydi_00240   Lydi_00260 Lydi_00260

Lydi_00250 : CDS information

close this sectionLocation

Organism
StrainTP-A0598 (=NBRC 110027)
Entry nameLydicamycin
Contig
Start / Stop / Direction115,220 / 116,272 / + [in whole cluster]
115,220 / 116,272 / + [in contig]
Location115220..116272 [in whole cluster]
115220..116272 [in contig]
TypeCDS
Length1,053 bp (350 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative transcriptional regulator
Product (GenBank)putative AsnC family transcriptional regulator
GeneTPA0598_03_00890
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[26380643] Draft genome sequence of marine-derived Streptomyces sp. TP-A0598, a producer of anti-MRSA antibiotic lydicamycins. (Stand Genomic Sci. , 2015)
comment
Streptomyces sp. TP-A0598におけるputative lydicamycin biosynthetic gene clusterの報告。
このclusterが実際にlydicamycin産生に関わるかどうかの実験的な確認はされていない。

TPA0598_03_00890(344aa): transcriptional regulator

本文中にコメントなし。
Family/Domain
FD
IPR019888
comment
[IPR019888] Transcription regulator AsnC-type (Family)
Molecular Function
GO:0043565 sequence-specific DNA binding
GO:0003700 transcription factor activity, sequence-specific DNA binding

close this sectionSequence

selected fasta
>putative transcriptional regulator [putative AsnC family transcriptional regulator]
MSSETEVPRPEQLDEDDLLLANALQTAPRATWSELGKVLGQDAVTLARRWERLSSKGLAW
VTPALGPGLLYRTCRAFVEIHCEPGSAAQVSAELSHQPHVLTLQHVAGTYDLFAIAFTPD
FASMSDYLLTSLPRQEGVVRVRSHLVTRNFRTGSQWRLGVLNQRQERTLLRTGPEPQGAE
ATAYSTWERELIVALSKDGRLRYSDIATELGVTPRTVQRRLNRLLGNRDLLLRCDVARPL
AGWPTGALLWLNVPDERLEEAGRTLGAFPETRSCAALSGANNLLVTVTLHSVDALHDWAV
QLRQALPYAQIADRSVVLRQDKLCGHLLDVWGRSRGVVPLDIWRPSGLSR
selected fasta
>putative transcriptional regulator [putative AsnC family transcriptional regulator]
GTGAGCAGCGAAACCGAGGTGCCGCGTCCGGAGCAGCTGGACGAGGACGATCTGCTGCTG
GCCAACGCCCTCCAGACCGCGCCCCGCGCGACATGGAGCGAGCTGGGAAAGGTGCTCGGC
CAGGACGCGGTGACACTGGCCCGCCGATGGGAGCGCCTCAGCAGCAAGGGCCTGGCCTGG
GTCACCCCCGCGCTGGGCCCCGGTCTCCTCTACCGGACGTGCCGGGCCTTCGTCGAAATC
CACTGCGAGCCGGGCAGCGCCGCTCAGGTATCGGCCGAGCTGTCCCACCAGCCCCACGTG
CTCACCCTCCAGCATGTCGCCGGCACCTATGACCTGTTCGCGATCGCCTTCACCCCGGAC
TTCGCCTCGATGTCCGACTACCTCCTCACGAGCCTGCCCCGGCAGGAGGGCGTCGTCCGG
GTCCGTTCCCATCTGGTGACCCGCAACTTCCGCACGGGATCGCAATGGCGCCTGGGCGTG
CTGAACCAGCGCCAGGAGCGGACCCTGCTCCGCACCGGGCCGGAACCGCAGGGCGCCGAG
GCCACCGCGTACAGCACCTGGGAGCGCGAACTGATCGTCGCGCTGAGCAAAGACGGCCGG
CTCCGCTACTCCGATATCGCCACCGAGCTGGGCGTCACACCCCGGACCGTGCAGCGCCGG
CTGAACCGGCTGCTGGGCAACCGCGACCTGCTCCTGCGCTGCGATGTCGCCCGCCCCCTC
GCGGGCTGGCCGACCGGCGCCCTGCTGTGGCTCAACGTCCCGGACGAGCGGCTGGAGGAG
GCCGGCCGTACGCTCGGTGCCTTCCCGGAGACCCGCAGCTGCGCGGCGCTGTCCGGCGCG
AACAACCTGCTGGTCACCGTCACCCTGCACTCGGTGGACGCGCTCCACGACTGGGCGGTG
CAGCTGCGCCAGGCGCTGCCGTACGCGCAGATCGCGGACCGTTCCGTGGTGCTGCGCCAG
GACAAGCTGTGCGGTCATCTGCTGGATGTGTGGGGACGAAGCCGTGGCGTCGTCCCCCTC
GACATCTGGCGGCCGAGCGGCCTCAGCCGGTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR011008 Dimeric alpha-beta barrel (Domain)
[72-151] 8.2e-14 SSF54909 [243-327] 6.3e-07 SSF54909
SSF54909   Dimeric alpha+beta barrel
IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain)
[11-58] 0.0003 G3DSA:1.10.10.10 [188-225] 3e-07 G3DSA:1.10.10.10
G3DSA:1.10.10.10   no description
IPR019887 Transcription regulator AsnC-type, C-terminal (Domain)
[78-148] 4.6e-10 PF01037
PF01037   AsnC_trans_reg
[76-150] 1.2e-11 G3DSA:3.30.70.920
G3DSA:3.30.70.920   no description
IPR019888 Transcription regulator AsnC-type (Family)
[13-118] 0.00038 SM00344 [189-289] 0.00021 SM00344
SM00344   helix_turn_helix ASNC type
SignalP No significant hit
TMHMM No significant hit
Lydi_00240 Lydi_00240   Lydi_00260 Lydi_00260
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