Function : Vancomycin resistance (via D-Ala-D-Lac precursor)
Function Description
| ID | NFUNC_0089 |
|---|---|
| Created | 2014-07-28 |
| Description | Resistance to vancomycin is due to the presence of operons that encode enzymes (1) for synthesis of low-affinity precursors, in which the C-terminal D-alanine residue is replaced by D-lactate, thus modifying the vancomyin-binding target; and (2) for elimination of the high-affinity precursors that are normally produced by the host, thus removing the vancomycin-binding target. |
| Comment | Not assigned |
| Cross Reference |
Wikipedia Vancomycin MetaCyc vancomycin resistance I PMID 16323116 PMID 24220108 |
Function Constitution
Potential Functional Microbe
