Function : Vancomycin resistance (via D-Ala-D-Lac precursor)
Function Description
ID | NFUNC_0089![]() |
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Created | 2014-07-28 |
Description | Resistance to vancomycin is due to the presence of operons that encode enzymes (1) for synthesis of low-affinity precursors, in which the C-terminal D-alanine residue is replaced by D-lactate, thus modifying the vancomyin-binding target; and (2) for elimination of the high-affinity precursors that are normally produced by the host, thus removing the vancomycin-binding target. |
Comment | Not assigned |
Cross Reference |
Wikipedia Vancomycin MetaCyc vancomycin resistance I PMID 16323116 PMID 24220108 |
Function Constitution
Potential Functional Microbe
