遺伝子 : Coenzyme PQQ synthesis protein F (PQQF)

遺伝子情報

ID	NRULE_0095
遺伝子ID	PQQF
作成日	2012/12/13
タンパク質名	Protein name Full Coenzyme PQQ synthesis protein F EC EC 3.4.24.- Synonym Full Pyrroloquinoline quinone biosynthesis protein F
遺伝子名	pqqF
遺伝子条件	TIGRFAMs; TIGR02110; hit=1
参照	Gene Ontology GO GO:0008234, F:cysteine-type peptidase activity, IEA:InterPro GO:0004222, F:metalloendopeptidase activity, IEA:InterPro GO:0008270, F:zinc ion binding, IEA:InterPro GO:0006508, P:proteolysis, IEA:UniProtKB-KW GO:0018189, P:pyrroloquinoline quinone biosynthetic process, IEA:UniProtKB-KW Phylogenomic databases KO K01422, - Enzyme and pathway databases UniPathway UPA00539, - Family and domain databases InterPro IPR011249, Metalloenz_metal-bd IPR011237, Pept_M16_core IPR011765, Pept_M16_N IPR001431, Pept_M16_Zn_BS IPR011844, Pept_M16A_PQQ_synth_PqqF IPR007863, Peptidase_M16_C Pfam PF00675, Peptidase_M16, 1 PF05193, Peptidase_M16_C, 1 TIGRFAMs TIGR02110, PQQ_syn_pqqF, 1 PROSITE PS00143, INSULINASE, 1
配列の特徴	P27508 Klebsiella pneumoniae. ACT_SITE 52 Proton acceptor (By similarity). METAL 49 Zinc (By similarity). METAL 53 Zinc (By similarity). METAL 130 Zinc (By similarity). Q9I2D2 Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228). ACT_SITE 58 Proton acceptor (By similarity). METAL 55 Zinc (By similarity). METAL 59 Zinc (By similarity). METAL 136 Zinc (By similarity).
注釈	Function Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. It is thought that this protein is a protease that cleaves peptides bond in a small peptide (gene pqqA), providing the glutamate and tyrosine residues which are necessary for the synthesis of PQQ Cofactor Binds 1 zinc ion per subunit (By similarity) Pathway Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis Sequence similarities Belongs to the peptidase M16 family
参考文献	P27508 Klebsiella pneumoniae. 1313537 Nucleotide sequence and structure of the Klebsiella pneumoniae pqq operon. (Mol Gen Genet. 1992) Q9I2D2 Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228). 10984043 Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. (Nature. 2000)

関与する機能

機能名
Pyrroloquinoline quinone biosynthesis

該当CDS

学名	NBRC番号	CDS	タンパク質名
Cystobacter fuscus	100088	D187_002726	hypothetical protein
Enterobacter aerogenes	13534	EAE_19580	coenzyme PQQ biosynthesis protein PqqF
Enterobacter hormaechei	105718	HMPREF9086_0393	coenzyme PQQ synthesis protein F
Klebsiella pneumoniae	14438	KPR_2415
Klebsiella pneumoniae subsp. rhinoscleromatis	105682	HMPREF0484_4545	coenzyme PQQ biosynthesis protein PqqF
Pseudomonas putida	100650	PP_0381	coenzyme PQQ synthesis protein F
Pseudomonas stutzeri	14165	PSTAB_1875	pyrroloquinoline quinone biosynthesis protein F
Rahnella aquatilis	105701	Rahaq2_4820	coenzyme PQQ biosynthesis probable peptidase PqqF