遺伝子 : Bleomycin resistance protein (BLE)

遺伝子情報

ID	NRULE_0096
遺伝子ID	BLE
作成日	2012/12/07
タンパク質名	Protein name Full Bleomycin resistance protein Short BRP Synonym Full Phleomycin resistance protein
遺伝子名	ble
遺伝子条件	PRINTS; PR00311; hit=1
参照	Gene Ontology GO GO:0008144, F:drug binding, IEA:InterPro GO:0046677, P:response to antibiotic, IEA:UniProtKB-KW Family and domain databases InterPro IPR000335, Bleomycin-R IPR025870, Glyoxalase-like_dom Pfam PF12681, Glyoxalase_2, 1 PRINTS PR00311, BLEOMYCINRST
配列の特徴	該当データなし
注釈	Function Binding protein with a strong affinity to the bleomycin family of antibiotics, which confers resistance to these antibiotics by preventing the bleomycin-induced DNA breakage Sequence similarities Belongs to the bleomycin resistance protein family
参考文献	Q7DJ53 Staphylococcus aureus. 2437604 Plasmid-determined bleomycin resistance in Staphylococcus aureus. (Plasmid. 1987) P17493 Streptoalloteichus hindustanus. 1695734 Cassettes of the Streptoalloteichus hindustanus ble gene for transformation of lower and higher eukaryotes to phleomycin resistance. (Nucleic Acids Res. 1990) Q53793 Streptomyces verticillus. 7530225 Gene organization in the bleomycin-resistance region of the producer organism Streptomyces verticillus. (Gene. 1994)

関与する機能

機能名
Bleomycin resistance

該当CDS

学名	NBRC番号	CDS	タンパク質名
Caulobacter segnis	15250	Cseg_0988	Glyoxalase/bleomycin resistance protein/dioxygenase
Cystobacter fuscus	100088	D187_001341	bleomycin resistance protein
Ktedonobacter racemifer		Krac_1063	Glyoxalase/bleomycin resistance protein/dioxygenase
Streptomyces mobaraensis	13819	H340_17507	Glyoxalase/bleomycin resistance protein/dioxygenase