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遺伝子 : Streptomycin 3''-adenylyltransferase (ANT3)

遺伝子情報

ID NRULE_0154
遺伝子ID ANT3
作成日 2013/03/06
タンパク質名
Protein name
Full
Streptomycin 3''-adenylyltransferase
EC
EC 2.7.7.47
遺伝子名 aadA, ant
遺伝子条件 PIRSF; PIRSF000819; hit=1
参照
Gene Ontology
GO
GO:0009012, F:aminoglycoside 3''-adenylyltransferase activity, IEA:EC
GO:0005524, F:ATP binding, IEA:UniProtKB-KW
GO:0046677, P:response to antibiotic, IEA:UniProtKB-KW
Phylogenomic databases
KO
K00984, -
Family and domain databases
InterPro
IPR025184, DUF4111
IPR002934, Nucleotidyltransferase
IPR024172, Streptomycin_AdlTfrase
Pfam
PF13427, DUF4111, 1
PF01909, NTP_transf_2, 1
PIRSF
PIRSF000819, Streptomycin_3-adenylyltransf, 1
配列の特徴 該当データなし
注釈
Function
Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
Catalytic activity
ATP + streptomycin = diphosphate + 3''- adenylylstreptomycin
参考文献
P0AG05 Escherichia coli.
2997737
Nucleotide sequence of the transposon Tn7 gene encoding an aminoglycoside-modifying enzyme, 3"(9)-O-nucleotidyltransferase. (Nucleic Acids Res. 1985)
P0A0D2 Staphylococcus aureus.
2993813
Nucleotide sequence of a spectinomycin adenyltransferase AAD(9) determinant from Staphylococcus aureus and its relationship to AAD(3") (9). (Mol Gen Genet. 1985)



関与する機能

機能名
Aminoglycoside resistance (by aminoglycoside O-nucleotidyltransferase)
Streptomycin resistance

該当CDS

データダウンロード
学名 NBRC番号 CDS タンパク質名
Clostridium clariflavum101661Clocl_3451nucleotidyltransferase family protein
Clostridium kluyveri12016CKR_2315hypothetical protein
Limnochorda pilosa110152LIP_2795hypothetical protein
Myroides odoratus14945Myrod_2991DNA polymerase beta domain protein region
Ochrobactrum intermedium15820OINT_1000421Streptomycin 3'-adenylyltransferase
Pseudomonas stutzeri14165PSTAB_2058aminoglycoside resistance protein
Streptomyces ghanaensis15414SSFG_06671nucleotidyltransferase
Streptomyces venezuelae13096SVEN_0221Spectinomycin 9-O-adenylyltransferase
Tetragenococcus halophilus12172TEH_23880hypothetical protein