遺伝子 : Dimethylglycine N-methyltransferase (SDMT)

遺伝子情報

ID	NRULE_0180
遺伝子ID	SDMT
作成日	2013/03/27
タンパク質名	Protein name Full Dimethylglycine N-methyltransferase EC EC 2.1.1.161
遺伝子名	該当データなし
遺伝子条件	BLASTP; Q7U4Z9; hit=1; score=500; pid=35
参照	Gene Ontology GO GO:0052729, F:dimethylglycine N-methyltransferase activity, IDA:UniProtKB GO:0019286, P:glycine betaine biosynthetic process from glycine, IDA:UniProtKB Phylogenomic databases eggNOG COG0500, - HOGENOM HOG000230375, - KO K13042, - Enzyme and pathway databases UniPathway UPA00530, UER00383 Family and domain databases InterPro IPR013216, Methyltransf_11 Pfam PF08241, Methyltransf_11, 1
配列の特徴	該当データなし
注釈	Function Catalyzes the methylation of dimethylglycine to betaine with S-adenosylmethionine (AdoMet) acting as the methyl donor. It has strict specificity for dimethylglycine as the methyl group acceptors Catalytic activity S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine Pathway Amine and polyamine biosynthesis; betaine biosynthesis via glycine pathway; betaine from glycine: step 3/3 Subunit structure Monomer Sequence similarities Belongs to the methyltransferase superfamily
参考文献	Q7U4Z9 Synechococcus sp. (strain WH8102). 17019606 Identification of glycine betaine as compatible solute in Synechococcus sp. WH8102 and characterization of its N-methyltransferase genes involved in betaine synthesis. (Arch Microbiol. 2006) Q83WC3 Aphanothece halophytica. 12466265 Isolation and functional characterization of N-methyltransferases that catalyze betaine synthesis from glycine in a halotolerant photosynthetic organism Aphanothece halophytica. (J Biol Chem. 2003)

関与する機能

機能名
Betaine biosynthesis (from glycine)

該当CDS

学名	NBRC番号	CDS	タンパク質名
Labrenzia aggregata	16684	SIAM614_20226	putative glycine-sarcosine methyltransferase
Microscilla marina	16560	M23134_00297	dimethylglycine N-methyltransferase
Nitrospina gracilis		NITGR_160023	Methyltransferase type 11
Stackebrandtia nassauensis	102104	Snas_2966	Methyltransferase type 11
Streptomyces mobaraensis	13819	H340_30558	sarcosine/dimethylglycine N-methyltransferase