BLAST table : FR008_00160

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q6W5Q0_9ACTO
(Q6W5Q0)		 
[query] 1 - 10625 (10625)
[subject] 1 - 10625 (10625)
 0.0 20650   100% FscC fscC Streptomyces sp. FR-008
2
 D6B4Q9_9ACTO
(D6B4Q9)		 
[query] 4793 - 10625 (10625)
[subject] 112 - 5945 (5945)
(8 hsp)		 0.0 10500   98% Polyketide synthase SSHG_00090 Streptomyces albus J1074
3
 D7BRD4_STRBB
(D7BRD4)		 
[query] 35 - 8689 (10625)
[subject] 1063 - 9869 (9950)
(17 hsp)		 0.0 8462   57% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
4
 E0L044_STRVO
(E0L044)		 
[query] 3 - 6945 (10625)
[subject] 4 - 7143 (7224)
(6 hsp)		 0.0 7003   57% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
5
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 32 - 8697 (10625)
[subject] 4892 - 13878 (14130)
(27 hsp)		 0.0 6331   44% Type I modular polyketide synthase mlsB
MUP032c		 Mycobacterium ulcerans (strain Agy99)
6
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 35 - 5304 (10625)
[subject] 1578 - 6819 (6831)
(13 hsp)		 0.0 6245   65% ScnS1 scnS1 Streptomyces chattanoogensis
7
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 35 - 5230 (10625)
[subject] 1562 - 6705 (6797)
(13 hsp)		 0.0 6143   66% PimS1 protein
Polyketide synthase		 pimS1 Streptomyces natalensis
8
 A4X8L0_SALTO
(A4X8L0)		 
[query] 1674 - 8694 (10625)
[subject] 58 - 7134 (7210)
(7 hsp)		 0.0 6029   52% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
9
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 1433 - 6945 (10625)
[subject] 5215 - 10833 (10917)
(16 hsp)		 0.0 6022   61% AmphC amphC Streptomyces nodosus
10
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 1681 - 8693 (10625)
[subject] 18 - 7035 (7110)
(10 hsp)		 0.0 5999   52% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
11
 E8S0C5_MICSL
(E8S0C5)		 
[query] 1329 - 7837 (10625)
[subject] 1117 - 7719 (9937)
(29 hsp)		 0.0 5994   55% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
12
 D9T6W4_MICAI
(D9T6W4)		 
[query] 1329 - 7837 (10625)
[subject] 1117 - 7718 (9936)
(29 hsp)		 0.0 5989   55% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
13
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 1433 - 6945 (10625)
[subject] 5264 - 11012 (11096)
(16 hsp)		 0.0 5707   58% NysC nysC Streptomyces noursei
14
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 1433 - 6945 (10625)
[subject] 5223 - 10788 (10876)
(15 hsp)		 0.0 5609   60% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
15
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 5 - 6955 (10625)
[subject] 6 - 6808 (6872)
(11 hsp)		 0.0 5550   50% Polyketide synthase KijS2 Actinomadura kijaniata
16
 B5L6K9_MICCH
(B5L6K9)		 
[query] 1782 - 8755 (10625)
[subject] 33 - 6996 (7007)
(7 hsp)		 0.0 5460   49% Putative type I polyketide synthase Micromonospora chalcea
17
 Q82QT4_STRAW
(Q82QT4)		 
[query] 1329 - 6941 (10625)
[subject] 2078 - 7657 (7746)
(23 hsp)		 0.0 5232   55% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
18
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 1345 - 8697 (10625)
[subject] 4440 - 12100 (12352)
(26 hsp)		 0.0 5162   43% Type I modular polyketide synthase, MlsB mlsB
MULP_051		 Mycobacterium liflandii 128FXT
19
 Q52V52_9ACTO
(Q52V52)		 
[query] 4 - 5230 (10625)
[subject] 3 - 5345 (5432)
(9 hsp)		 0.0 5076   57% Polyketide synthase type I Streptomyces aizunensis
20
 D9VEY7_9ACTO
(D9VEY7)		 
[query] 3456 - 8692 (10625)
[subject] 55 - 5218 (5260)
(10 hsp)		 0.0 4878   55% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
21
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 3 - 5227 (10625)
[subject] 2 - 5014 (5099)
(8 hsp)		 0.0 4875   56% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
22
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 1787 - 6945 (10625)
[subject] 38 - 5110 (5400)
(9 hsp)		 0.0 4793   56% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
23
 B4VDY6_9ACTO
(B4VDY6)		 
[query] 30 - 4839 (10625)
[subject] 14 - 4847 (4894)
(9 hsp)		 0.0 4691   56% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
24
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 3 - 5242 (10625)
[subject] 2 - 5297 (5588)
(7 hsp)		 0.0 4690   53% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
25
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1 - 5235 (10625)
[subject] 1 - 5106 (5176)
(7 hsp)		 0.0 4678   54% ObsB Saccharopolyspora spinosa
26
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 35 - 5230 (10625)
[subject] 1026 - 6296 (6383)
(16 hsp)		 0.0 4605   51% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
27
 E8WEN5_STRFA
(E8WEN5)		 
[query] 3 - 5230 (10625)
[subject] 2 - 5071 (5156)
(8 hsp)		 0.0 4492   53% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
28
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 3 - 5232 (10625)
[subject] 2 - 5237 (5321)
(7 hsp)		 0.0 4477   52% Polyketide synthase natC Streptomyces sp. CS
29
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 1389 - 6933 (10625)
[subject] 4864 - 10132 (10223)
(17 hsp)		 0.0 4463   50% Polyketide synthase rapB Streptomyces hygroscopicus
30
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 35 - 6966 (10625)
[subject] 1161 - 7508 (7525)
(17 hsp)		 0.0 4458   45% FkbB fkbB Streptomyces hygroscopicus subsp. ascomyceticus
31
 E9KTB5_STRKN
(E9KTB5)		 
[query] 1690 - 8207 (10625)
[subject] 1081 - 7218 (7591)
(16 hsp)		 0.0 4432   45% Polyketide synthase fkbB
Tcs_SK_031		 Streptomyces kanamyceticus
32
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 35 - 5232 (10625)
[subject] 992 - 5972 (6078)
(14 hsp)		 0.0 4396   53% ObsA Saccharopolyspora spinosa
33
 D1XUK5_9ACTO
(D1XUK5)		 
[query] 3530 - 8746 (10625)
[subject] 34 - 5128 (5157)
(8 hsp)		 0.0 4386   52% Short-chain dehydrogenase/reductase SDR SACTEDRAFT_6365 Streptomyces sp. SA3_actE
34
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 1689 - 6946 (10625)
[subject] 921 - 6168 (6241)
(15 hsp)		 0.0 4288   51% Polyketide synthase KijS1 Actinomadura kijaniata
35
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1 - 5230 (10625)
[subject] 1 - 5255 (5339)
(8 hsp)		 0.0 4275   50% Polyketide synthase natB Streptomyces sp. CS
36
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 35 - 6970 (10625)
[subject] 1183 - 7554 (7576)
(12 hsp)		 0.0 4258   44% FK506 polyketide synthase fkbB Streptomyces sp. MA6548
37
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 1681 - 6255 (10625)
[subject] 918 - 5575 (5582)
(16 hsp)		 0.0 4209   51% Polyketide synthase type I becA Streptomyces sp. DSM 21069
38
 F8JUL0_STRCT
(F8JUL0)		 
[query] 1674 - 6255 (10625)
[subject] 920 - 5432 (5950)
(22 hsp)		 0.0 4163   55% Putative polyketide synthase SCAT_3270 Streptomyces cattleya
39
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 1327 - 6584 (10625)
[subject] 3324 - 8581 (10827)
(38 hsp)		 0.0 4100   50% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
40
 C6K7D8_9ACTO
(C6K7D8)		 
[query] 1408 - 6946 (10625)
[subject] 2783 - 7863 (7938)
(19 hsp)		 0.0 3989   48% Polyketide synthase rapA Actinoplanes sp. N902-109
41
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 1341 - 6587 (10625)
[subject] 3686 - 8795 (9528)
(29 hsp)		 0.0 3985   48% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
42
 B5L6K8_MICCH
(B5L6K8)		 
[query] 1690 - 6953 (10625)
[subject] 923 - 6235 (6305)
(15 hsp)		 0.0 3974   47% Putative type I polyketide synthase Micromonospora chalcea
43
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 1341 - 6587 (10625)
[subject] 3802 - 8915 (9648)
(28 hsp)		 0.0 3973   48% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
44
 F4F7F4_VERMA
(F4F7F4)		 
[query] 3434 - 8689 (10625)
[subject] 864 - 5748 (5781)
(22 hsp)		 0.0 3969   48% Modular polyketide synthase VAB18032_16435 Verrucosispora maris (strain AB-18-032)
45
 B1W5P4_STRGG
(B1W5P4)		 
[query] 3521 - 8767 (10625)
[subject] 25 - 4824 (4843)
(12 hsp)		 0.0 3954   48% Putative type-I PKS pks3-2
SGR_6372		 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
46
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 3 - 4407 (10625)
[subject] 6 - 4559 (7026)
(14 hsp)		 0.0 3948   52% Polyketide synthase pldAII Streptomyces platensis
47
 A8M6C7_SALAI
(A8M6C7)		 
[query] 1781 - 6950 (10625)
[subject] 28 - 5186 (5255)
(7 hsp)		 0.0 3909   49% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
48
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 1 - 4400 (10625)
[subject] 1 - 4475 (5214)
(14 hsp)		 0.0 3903   53% Polyketide synthase idmN Streptomyces antibioticus
49
 F8JVX1_STRCT
(F8JVX1)		 
[query] 1685 - 6145 (10625)
[subject] 941 - 5424 (6125)
(21 hsp)		 0.0 3893   52% Putative 6-methylsalicylic acid synthase SCAT_0136 Streptomyces cattleya 2.3.1.165

2.3.1.94
50
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1 - 4407 (10625)
[subject] 1 - 4266 (8301)
(15 hsp)		 0.0 3891   55% Type I polyketide synthase sfaH Streptomyces flaveolus
51
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 1786 - 6948 (10625)
[subject] 36 - 5441 (5532)
(8 hsp)		 0.0 3863   48% Type I polyketide synthase AVES 3 aveA3
SAV942
SAV_942		 Streptomyces avermitilis
52
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1788 - 6945 (10625)
[subject] 35 - 5005 (5060)
(9 hsp)		 0.0 3862   49% Rifamycin polyketide synthase rifB
AMED_0618		 Amycolatopsis mediterranei (strain U-32)
53
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 1788 - 6945 (10625)
[subject] 35 - 5005 (5060)
(9 hsp)		 0.0 3860   49% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
54
 O52789_AMYMD
(O52789)		 
[query] 1788 - 6945 (10625)
[subject] 44 - 5014 (5069)
(9 hsp)		 0.0 3857   49% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
55
 Q52V50_9ACTO
(Q52V50)		 
[query] 1412 - 5244 (10625)
[subject] 3549 - 7436 (7510)
(14 hsp)		 0.0 3804   57% Polyketide synthase type I Streptomyces aizunensis
56
 Q0PCZ9_STRHA
(Q0PCZ9)		 Jump to Halsto_00060 
[query] 4 - 4401 (10625)
[subject] 3 - 4504 (5232)
(12 hsp)		 0.0 3780   52% Type I polyketide synthase hlsF Streptomyces halstedii
57
 A8LUX2_SALAI
(A8LUX2)		 
[query] 1694 - 6118 (10625)
[subject] 905 - 5198 (7279)
(32 hsp)		 0.0 3764   53% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
58
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 5 - 4874 (10625)
[subject] 4 - 4507 (6260)
(19 hsp)		 0.0 3751   49% Polyketide synthase rapC Streptomyces hygroscopicus
59
 B4VB11_9ACTO
(B4VB11)		 
[query] 1472 - 5258 (10625)
[subject] 1 - 3852 (3928)
(9 hsp)		 0.0 3669   57% Polyketide synthase type I SSAG_04921 Streptomyces sp. Mg1
60
 D7F1M0_9ACTO
(D7F1M0)		 
[query] 3 - 4407 (10625)
[subject] 4 - 4402 (5136)
(14 hsp)		 0.0 3645   49% Polyketide synthase tsnAII Streptomyces longisporoflavus
61
 Q0RIF5_FRAAA
(Q0RIF5)		 
[query] 1697 - 6941 (10625)
[subject] 918 - 6353 (6432)
(14 hsp)		 0.0 3640   47% Putative type I polyketide synthase FRAAL4072 Frankia alni (strain ACN14a) 2.3.1.-
62
 F8AWN2_9ACTO
(F8AWN2)		 
[query] 3431 - 7846 (10625)
[subject] 1130 - 5932 (6077)
(30 hsp)		 0.0 3639   49% (Acyl-carrier-protein) S-acetyltransferase., 6-deoxyerythronolide-B synthase FsymDg_1936 Frankia symbiont of Datisca glomerata 2.3.1.38

2.3.1.94
63
 Q52V53_9ACTO
(Q52V53)		 
[query] 3070 - 6957 (10625)
[subject] 1132 - 5138 (5207)
(13 hsp)		 0.0 3635   54% Polyketide synthase type I Streptomyces aizunensis
64
 Q93H87_STRAW
(Q93H87)		 
[query] 1329 - 5231 (10625)
[subject] 2078 - 5960 (6048)
(22 hsp)		 0.0 3605   55% Modular polyketide synthase pteA1 Streptomyces avermitilis
65
 D9VBL5_9ACTO
(D9VBL5)		 
[query] 3436 - 7612 (10625)
[subject] 892 - 4982 (5113)
(24 hsp)		 0.0 3593   52% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
66
 Q52V49_9ACTO
(Q52V49)		 
[query] 4 - 3518 (10625)
[subject] 2 - 3586 (3872)
(7 hsp)		 0.0 3522   57% Polyketide synthase type I Streptomyces aizunensis
67
 D7C2B8_STRBB
(D7C2B8)		 
[query] 1408 - 4870 (10625)
[subject] 3256 - 6726 (7498)
(29 hsp)		 0.0 3522   58% Type I modular polyketide synthase pks3-2
SBI_00651		 Streptomyces bingchenggensis (strain BCW-1)
68
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 1412 - 5230 (10625)
[subject] 3396 - 7192 (7488)
(15 hsp)		 0.0 3493   55% ObsC Saccharopolyspora spinosa
69
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 37 - 4869 (10625)
[subject] 20 - 5038 (16990)
(38 hsp)		 0.0 3487   43% Type I modular polyketide synthase mlsA1
MUP040c		 Mycobacterium ulcerans (strain Agy99)
70
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 1416 - 5230 (10625)
[subject] 1756 - 5626 (5718)
(15 hsp)		 0.0 3472   51% ChlA3 Streptomyces antibioticus
71
 Q0PD02_STRHA
(Q0PD02)		 Jump to Halsto_00030 
[query] 1394 - 5231 (10625)
[subject] 1189 - 5131 (5220)
(14 hsp)		 0.0 3468   53% Type I polyketide synthase hlsC Streptomyces halstedii
72
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 37 - 4869 (10625)
[subject] 20 - 5036 (17019)
(39 hsp)		 0.0 3454   44% Type I modular polyketide synthase, MlsA1 mlsA1
MULP_065		 Mycobacterium liflandii 128FXT
73
 C0Z477_STRVN
(C0Z477)		 
[query] 1689 - 6133 (10625)
[subject] 958 - 5386 (6130)
(16 hsp)		 0.0 3442   50% Type I polyketide synthase, loading module and modules 1-3 ken16 Streptomyces violaceoruber
74
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 1787 - 5227 (10625)
[subject] 33 - 3527 (3612)
(7 hsp)		 0.0 3432   55% LipPks3 lipPks3 Streptomyces aureofaciens
75
 F1D8Z6_9ACTO
(F1D8Z6)		 
[query] 3157 - 8207 (10625)
[subject] 2482 - 7277 (7655)
(15 hsp)		 0.0 3366   46% FkbB Streptomyces sp. MJM7001
76
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 3157 - 8207 (10625)
[subject] 2473 - 7268 (7646)
(15 hsp)		 0.0 3359   46% Polyketide synthase fkbB
Tcs_11604BP_028		 Streptomyces sp. KCTC 11604BP
77
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 1447 - 5230 (10625)
[subject] 1871 - 5740 (5826)
(15 hsp)		 0.0 3323   53% Polyketide synthase modules 1-3 vinP1 Streptomyces halstedii
78
 D7P611_CHOCO
(D7P611)		 
[query] 491 - 4874 (10625)
[subject] 988 - 5468 (6255)
(20 hsp)		 0.0 3316   47% TugA tugA Chondromyces crocatus
79
 C3VLZ4_9ACTO
(C3VLZ4)		 
[query] 3526 - 6956 (10625)
[subject] 34 - 3294 (3365)
(8 hsp)		 0.0 3304   55% Polyketide synthase type I mlaD Streptomyces sp. MP39-85
80
 E0L075_STRVO
(E0L075)		 
[query] 3 - 3136 (10625)
[subject] 2 - 3157 (5786)
(20 hsp)		 0.0 3295   58% Beta-ketoacyl synthase StrviDRAFT_8303 Streptomyces violaceusniger Tu 4113
81
 D9WQL2_9ACTO
(D9WQL2)		 
[query] 3526 - 6939 (10625)
[subject] 34 - 3284 (3284)
(7 hsp)		 0.0 3291   56% Modular polyketide synthase SSOG_07859 Streptomyces himastatinicus ATCC 53653
82
 C3VLW6_9ACTO
(C3VLW6)		 
[query] 3526 - 6956 (10625)
[subject] 34 - 3301 (3372)
(9 hsp)		 0.0 3253   55% Polyketide synthase type I becD Streptomyces sp. DSM 21069
83
 D6EJM4_STRLI
(D6EJM4)		 
[query] 1686 - 5247 (10625)
[subject] 958 - 4533 (4599)
(13 hsp)		 0.0 3247   54% Type I polyketide synthase SSPG_01356 Streptomyces lividans TK24
84
 Q8CJN6_STRCO
(Q8CJN6)		 
[query] 1686 - 5247 (10625)
[subject] 914 - 4491 (4557)
(13 hsp)		 0.0 3247   54% Putative type I polyketide synthase SCO6275 Streptomyces coelicolor
85
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 1782 - 5222 (10625)
[subject] 30 - 3491 (3596)
(6 hsp)		 0.0 3232   55% Polyketide synthase idmM Streptomyces antibioticus
86
 Q76KZ3_STRHA
(Q76KZ3)		 Jump to Vicen_00070 
[query] 1787 - 5237 (10625)
[subject] 33 - 3503 (3808)
(9 hsp)		 0.0 3231   55% Polyketide synthase modules 7-8 vinP4 Streptomyces halstedii
87
 D6C477_9ACTO
(D6C477)		 Jump to Meili_00310 
[query] 1310 - 5230 (10625)
[subject] 1668 - 5730 (5822)
(13 hsp)		 0.0 3220   50% Modular polyketide synthase meiA3 Streptomyces nanchangensis
88
 D9WQ83_9ACTO
(D9WQ83)		 
[query] 3 - 2975 (10625)
[subject] 11 - 3000 (3002)
(7 hsp)		 0.0 3212   59% Modular polyketide synthase SSOG_05757 Streptomyces himastatinicus ATCC 53653
89
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 1 - 4669 (10625)
[subject] 1 - 4568 (5066)
(15 hsp)		 0.0 3206   46% Putative polyketide synthase rubB Streptomyces achromogenes subsp. rubradiris
90
 D7BRE0_STRBB
(D7BRE0)		 
[query] 3529 - 6950 (10625)
[subject] 33 - 3534 (3619)
(9 hsp)		 0.0 3199   56% Modular polyketide synthase SBI_01982 Streptomyces bingchenggensis (strain BCW-1)
91
 Q9EX53_STRCO
(Q9EX53)		 
[query] 1786 - 5231 (10625)
[subject] 32 - 3489 (3576)
(7 hsp)		 0.0 3174   52% Putative type I polyketide synthase SCO6274 Streptomyces coelicolor
92
 D9WQ64_9ACTO
(D9WQ64)		 
[query] 1338 - 4411 (10625)
[subject] 540 - 3654 (3874)
(15 hsp)		 0.0 3172   57% Modular polyketide synthase SSOG_05738 Streptomyces himastatinicus ATCC 53653
93
 Q82QT5_STRAW
(Q82QT5)		 
[query] 1786 - 5239 (10625)
[subject] 32 - 3486 (3564)
(6 hsp)		 0.0 3149   54% Modular polyketide synthase pteA2
SAV418
SAV_418		 Streptomyces avermitilis
94
 A4FH84_SACEN
(A4FH84)		 
[query] 1788 - 5231 (10625)
[subject] 34 - 3401 (3481)
(7 hsp)		 0.0 3144   55% Type I modular polyketide synthase SACE_4140 Saccharopolyspora erythraea (strain NRRL 23338)
95
 Q5VKQ8_SACER
(Q5VKQ8)		 
[query] 1788 - 5231 (10625)
[subject] 34 - 3401 (3481)
(7 hsp)		 0.0 3144   55% Type I PKS pkeAII Saccharopolyspora erythraea
Streptomyces erythraeus
96
 Q93H86_STRAW
(Q93H86)		 
[query] 1795 - 5239 (10625)
[subject] 1 - 3446 (3524)
(7 hsp)		 0.0 3139   54% Modular polyketide synthase pteA2 Streptomyces avermitilis
97
 D9WQ70_9ACTO
(D9WQ70)		 
[query] 3065 - 6121 (10625)
[subject] 1831 - 4983 (5483)
(24 hsp)		 0.0 3135   57% Modular polyketide synthase SSOG_05744 Streptomyces himastatinicus ATCC 53653
98
 E0KFI9_STRVO
(E0KFI9)		 
[query] 1349 - 4411 (10625)
[subject] 2779 - 5934 (8238)
(40 hsp)		 0.0 3122   57% Beta-ketoacyl synthase StrviDRAFT_1372 Streptomyces violaceusniger Tu 4113
99
 D7F1M1_9ACTO
(D7F1M1)		 
[query] 1414 - 5230 (10625)
[subject] 1716 - 5543 (5630)
(15 hsp)		 0.0 3122   48% Polyketide synthase tsnAIII Streptomyces longisporoflavus
100
 D9VEW9_9ACTO
(D9VEW9)		 
[query] 3 - 3509 (10625)
[subject] 36 - 3404 (3487)
(7 hsp)		 0.0 3111   53% Polyketide synthase type I SSMG_05921 Streptomyces sp. AA4
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q6W5Q0_9ACTO
(Q6W5Q0)		 
[query] 1 - 10625 (10625)
[subject] 1 - 10625 (10625)
 0.0 20650   100%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
3
 D7BRD4_STRBB
(D7BRD4)		 
[query] 35 - 8689 (10625)
[subject] 1063 - 9869 (9950)
(17 hsp)		 0.0 8462   57%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
5
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 32 - 8697 (10625)
[subject] 4892 - 13878 (14130)
(27 hsp)		 0.0 6331   44%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
6
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 35 - 5304 (10625)
[subject] 1578 - 6819 (6831)
(13 hsp)		 0.0 6245   65%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
7
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 35 - 5230 (10625)
[subject] 1562 - 6705 (6797)
(13 hsp)		 0.0 6143   66%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
9
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 1433 - 6945 (10625)
[subject] 5215 - 10833 (10917)
(16 hsp)		 0.0 6022   61%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
10
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 1681 - 8693 (10625)
[subject] 18 - 7035 (7110)
(10 hsp)		 0.0 5999   52%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
13
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 1433 - 6945 (10625)
[subject] 5264 - 11012 (11096)
(16 hsp)		 0.0 5707   58%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
14
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 1433 - 6945 (10625)
[subject] 5223 - 10788 (10876)
(15 hsp)		 0.0 5609   60%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
15
 B3TMQ7_9ACTO
(B3TMQ7)		 
[query] 5 - 6955 (10625)
[subject] 6 - 6808 (6872)
(11 hsp)		 0.0 5550   50%
Product
Polyketide synthase
Gene
KijS2
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
16
 B5L6K9_MICCH
(B5L6K9)		 
[query] 1782 - 8755 (10625)
[subject] 33 - 6996 (7007)
(7 hsp)		 0.0 5460   49%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
17
 Q82QT4_STRAW
(Q82QT4)		 
[query] 1329 - 6941 (10625)
[subject] 2078 - 7657 (7746)
(23 hsp)		 0.0 5232   55%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
18
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 1345 - 8697 (10625)
[subject] 4440 - 12100 (12352)
(26 hsp)		 0.0 5162   43%
Product
Type I modular polyketide synthase, MlsB
Gene
mlsB
MULP_051
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
19
 Q52V52_9ACTO
(Q52V52)		 
[query] 4 - 5230 (10625)
[subject] 3 - 5345 (5432)
(9 hsp)		 0.0 5076   57%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
21
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 3 - 5227 (10625)
[subject] 2 - 5014 (5099)
(8 hsp)		 0.0 4875   56%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
22
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 1787 - 6945 (10625)
[subject] 38 - 5110 (5400)
(9 hsp)		 0.0 4793   56%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
24
 Q9ALM2_9PSEU
(Q9ALM2)		 Jump to Spino_00210 
[query] 3 - 5242 (10625)
[subject] 2 - 5297 (5588)
(7 hsp)		 0.0 4690   53%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
25
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 1 - 5235 (10625)
[subject] 1 - 5106 (5176)
(7 hsp)		 0.0 4678   54%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
26
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 35 - 5230 (10625)
[subject] 1026 - 6296 (6383)
(16 hsp)		 0.0 4605   51%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
28
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 3 - 5232 (10625)
[subject] 2 - 5237 (5321)
(7 hsp)		 0.0 4477   52%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
29
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 1389 - 6933 (10625)
[subject] 4864 - 10132 (10223)
(17 hsp)		 0.0 4463   50%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
30
 Q9KIE0_STRHY
(Q9KIE0)		 Jump to Asco_00140 
[query] 35 - 6966 (10625)
[subject] 1161 - 7508 (7525)
(17 hsp)		 0.0 4458   45%
Product
FkbB
Gene
fkbB
Organism
Streptomyces hygroscopicus subsp. ascomyceticus
1uniprot[Pubmed] 10863099 [Medline] 20323220
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.(Gene) [2000]
31
 E9KTB5_STRKN
(E9KTB5)		 
[query] 1690 - 8207 (10625)
[subject] 1081 - 7218 (7591)
(16 hsp)		 0.0 4432   45%
Product
Polyketide synthase
Gene
fkbB
Tcs_SK_031
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
32
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 35 - 5232 (10625)
[subject] 992 - 5972 (6078)
(14 hsp)		 0.0 4396   53%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
34
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 1689 - 6946 (10625)
[subject] 921 - 6168 (6241)
(15 hsp)		 0.0 4288   51%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
35
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 1 - 5230 (10625)
[subject] 1 - 5255 (5339)
(8 hsp)		 0.0 4275   50%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
36
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 35 - 6970 (10625)
[subject] 1183 - 7554 (7576)
(12 hsp)		 0.0 4258   44%
Product
FK506 polyketide synthase
Gene
fkbB
Organism
Streptomyces sp. MA6548
1uniprot[Pubmed] 9780228 [Medline] 98451508
The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.(Eur. J. Biochem.) [1998]
37
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 1681 - 6255 (10625)
[subject] 918 - 5575 (5582)
(16 hsp)		 0.0 4209   51%
Product
Polyketide synthase type I
Gene
becA
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
39
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 1327 - 6584 (10625)
[subject] 3324 - 8581 (10827)
(38 hsp)		 0.0 4100   50%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
41
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 1341 - 6587 (10625)
[subject] 3686 - 8795 (9528)
(29 hsp)		 0.0 3985   48%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
42
 B5L6K8_MICCH
(B5L6K8)		 
[query] 1690 - 6953 (10625)
[subject] 923 - 6235 (6305)
(15 hsp)		 0.0 3974   47%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
43
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 1341 - 6587 (10625)
[subject] 3802 - 8915 (9648)
(28 hsp)		 0.0 3973   48%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
44
 F4F7F4_VERMA
(F4F7F4)		 
[query] 3434 - 8689 (10625)
[subject] 864 - 5748 (5781)
(22 hsp)		 0.0 3969   48%
Product
Modular polyketide synthase
Gene
VAB18032_16435
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
45
 B1W5P4_STRGG
(B1W5P4)		 
[query] 3521 - 8767 (10625)
[subject] 25 - 4824 (4843)
(12 hsp)		 0.0 3954   48%
Product
Putative type-I PKS
Gene
pks3-2
SGR_6372
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
46
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 3 - 4407 (10625)
[subject] 6 - 4559 (7026)
(14 hsp)		 0.0 3948   52%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
48
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 1 - 4400 (10625)
[subject] 1 - 4475 (5214)
(14 hsp)		 0.0 3903   53%
Product
Polyketide synthase
Gene
idmN
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
50
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1 - 4407 (10625)
[subject] 1 - 4266 (8301)
(15 hsp)		 0.0 3891   55%
Product
Type I polyketide synthase
Gene
sfaH
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
51
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 1786 - 6948 (10625)
[subject] 36 - 5441 (5532)
(8 hsp)		 0.0 3863   48%
Product
Type I polyketide synthase AVES 3
Gene
aveA3
SAV942
SAV_942
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
52
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 1788 - 6945 (10625)
[subject] 35 - 5005 (5060)
(9 hsp)		 0.0 3862   49%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
53
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 1788 - 6945 (10625)
[subject] 35 - 5005 (5060)
(9 hsp)		 0.0 3860   49%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
55
 Q52V50_9ACTO
(Q52V50)		 
[query] 1412 - 5244 (10625)
[subject] 3549 - 7436 (7510)
(14 hsp)		 0.0 3804   57%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
58
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 5 - 4874 (10625)
[subject] 4 - 4507 (6260)
(19 hsp)		 0.0 3751   49%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
61
 Q0RIF5_FRAAA
(Q0RIF5)		 
[query] 1697 - 6941 (10625)
[subject] 918 - 6353 (6432)
(14 hsp)		 0.0 3640   47%
Product
Putative type I polyketide synthase
Gene
FRAAL4072
Organism
Frankia alni (strain ACN14a)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
63
 Q52V53_9ACTO
(Q52V53)		 
[query] 3070 - 6957 (10625)
[subject] 1132 - 5138 (5207)
(13 hsp)		 0.0 3635   54%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
64
 Q93H87_STRAW
(Q93H87)		 
[query] 1329 - 5231 (10625)
[subject] 2078 - 5960 (6048)
(22 hsp)		 0.0 3605   55%
Product
Modular polyketide synthase
Gene
pteA1
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
66
 Q52V49_9ACTO
(Q52V49)		 
[query] 4 - 3518 (10625)
[subject] 2 - 3586 (3872)
(7 hsp)		 0.0 3522   57%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
67
 D7C2B8_STRBB
(D7C2B8)		 
[query] 1408 - 4870 (10625)
[subject] 3256 - 6726 (7498)
(29 hsp)		 0.0 3522   58%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
68
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 1412 - 5230 (10625)
[subject] 3396 - 7192 (7488)
(15 hsp)		 0.0 3493   55%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
69
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 37 - 4869 (10625)
[subject] 20 - 5038 (16990)
(38 hsp)		 0.0 3487   43%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
70
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 1416 - 5230 (10625)
[subject] 1756 - 5626 (5718)
(15 hsp)		 0.0 3472   51%
Product
ChlA3
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
72
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 37 - 4869 (10625)
[subject] 20 - 5036 (17019)
(39 hsp)		 0.0 3454   44%
Product
Type I modular polyketide synthase, MlsA1
Gene
mlsA1
MULP_065
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
74
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 1787 - 5227 (10625)
[subject] 33 - 3527 (3612)
(7 hsp)		 0.0 3432   55%
Product
LipPks3
Gene
lipPks3
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
76
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 3157 - 8207 (10625)
[subject] 2473 - 7268 (7646)
(15 hsp)		 0.0 3359   46%
Product
Polyketide synthase
Gene
fkbB
Tcs_11604BP_028
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
77
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 1447 - 5230 (10625)
[subject] 1871 - 5740 (5826)
(15 hsp)		 0.0 3323   53%
Product
Polyketide synthase modules 1-3
Gene
vinP1
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
78
 D7P611_CHOCO
(D7P611)		 
[query] 491 - 4874 (10625)
[subject] 988 - 5468 (6255)
(20 hsp)		 0.0 3316   47%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
79
 C3VLZ4_9ACTO
(C3VLZ4)		 
[query] 3526 - 6956 (10625)
[subject] 34 - 3294 (3365)
(8 hsp)		 0.0 3304   55%
Product
Polyketide synthase type I
Gene
mlaD
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
82
 C3VLW6_9ACTO
(C3VLW6)		 
[query] 3526 - 6956 (10625)
[subject] 34 - 3301 (3372)
(9 hsp)		 0.0 3253   55%
Product
Polyketide synthase type I
Gene
becD
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
84
 Q8CJN6_STRCO
(Q8CJN6)		 
[query] 1686 - 5247 (10625)
[subject] 914 - 4491 (4557)
(13 hsp)		 0.0 3247   54%
Product
Putative type I polyketide synthase
Gene
SCO6275
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
85
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 1782 - 5222 (10625)
[subject] 30 - 3491 (3596)
(6 hsp)		 0.0 3232   55%
Product
Polyketide synthase
Gene
idmM
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
86
 Q76KZ3_STRHA
(Q76KZ3)		 Jump to Vicen_00070 
[query] 1787 - 5237 (10625)
[subject] 33 - 3503 (3808)
(9 hsp)		 0.0 3231   55%
Product
Polyketide synthase modules 7-8
Gene
vinP4
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
87
 D6C477_9ACTO
(D6C477)		 Jump to Meili_00310 
[query] 1310 - 5230 (10625)
[subject] 1668 - 5730 (5822)
(13 hsp)		 0.0 3220   50%
Product
Modular polyketide synthase
Gene
meiA3
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
89
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 1 - 4669 (10625)
[subject] 1 - 4568 (5066)
(15 hsp)		 0.0 3206   46%
Product
Putative polyketide synthase
Gene
rubB
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
90
 D7BRE0_STRBB
(D7BRE0)		 
[query] 3529 - 6950 (10625)
[subject] 33 - 3534 (3619)
(9 hsp)		 0.0 3199   56%
Product
Modular polyketide synthase
Gene
SBI_01982
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
91
 Q9EX53_STRCO
(Q9EX53)		 
[query] 1786 - 5231 (10625)
[subject] 32 - 3489 (3576)
(7 hsp)		 0.0 3174   52%
Product
Putative type I polyketide synthase
Gene
SCO6274
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
93
 Q82QT5_STRAW
(Q82QT5)		 
[query] 1786 - 5239 (10625)
[subject] 32 - 3486 (3564)
(6 hsp)		 0.0 3149   54%
Product
Modular polyketide synthase
Gene
pteA2
SAV418
SAV_418
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
94
 A4FH84_SACEN
(A4FH84)		 
[query] 1788 - 5231 (10625)
[subject] 34 - 3401 (3481)
(7 hsp)		 0.0 3144   55%
Product
Type I modular polyketide synthase
Gene
SACE_4140
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
95
 Q5VKQ8_SACER
(Q5VKQ8)		 
[query] 1788 - 5231 (10625)
[subject] 34 - 3401 (3481)
(7 hsp)		 0.0 3144   55%
Product
Type I PKS
Gene
pkeAII
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15925898
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004]
96
 Q93H86_STRAW
(Q93H86)		 
[query] 1795 - 5239 (10625)
[subject] 1 - 3446 (3524)
(7 hsp)		 0.0 3139   54%
Product
Modular polyketide synthase
Gene
pteA2
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]