BLAST table : Monen_00230

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q846W8_STRCM
(Q846W8)		 
[query] 1 - 140 (140)
[subject] 1 - 140 (140)
 4e-74 280   100% Probable monensin biosynthesis isomerase monBII Streptomyces cinnamonensis
2
 Q27W62_STRVO
(Q27W62)		 Jump to Niger_00130 
[query] 1 - 125 (140)
[subject] 1 - 125 (155)
 2e-36 155   57% NigBIII Streptomyces violaceoniger
3
 E0KCN4_STRVO
(E0KCN4)		 
[query] 1 - 125 (140)
[subject] 1 - 125 (155)
 2e-36 155   56% Putative uncharacterized protein StrviDRAFT_0009 Streptomyces violaceusniger Tu 4113
4
 D7BSM4_STRBB
(D7BSM4)		 
[query] 2 - 136 (140)
[subject] 160 - 291 (313)
(2 hsp)		 2e-21 105   44% Putative ketosteroid isomerase nanI
SBI_08403		 Streptomyces bingchenggensis (strain BCW-1)
5
 Q7WTD9_9ACTO
(Q7WTD9)		 Jump to Nanch_00240 
[query] 2 - 136 (140)
[subject] 160 - 291 (313)
(2 hsp)		 3e-21 105   44% NanI nanI Streptomyces nanchangensis
6
 D7F1M3_9ACTO
(D7F1M3)		 
[query] 1 - 139 (140)
[subject] 1 - 139 (139)
 2e-19 99.4 38% Epoxide hydrolase tsnB Streptomyces longisporoflavus
7
 B6ZK72_STRLS
(B6ZK72)		 Jump to Lasal_00210 
[query] 1 - 122 (140)
[subject] 1 - 127 (282)
(2 hsp)		 4e-17 91.3 42% Epoxide hydrolase lsd19 Streptomyces lasaliensis
8
 D9W5P7_9ACTO
(D9W5P7)		 
[query] 1 - 127 (140)
[subject] 1 - 147 (149)
 1e-16 90.1 32% Predicted protein SSNG_07477 Streptomyces sp. C
9
 B5M9L7_STRLS
(B5M9L7)		 Jump to Lasal2_00250 
[query] 1 - 122 (140)
[subject] 1 - 127 (282)
(2 hsp)		 1e-16 89.7 42% Epoxide hydrolase lasB Streptomyces lasaliensis
10
 D9W5P8_9ACTO
(D9W5P8)		 
[query] 1 - 127 (140)
[subject] 97 - 243 (243)
 1e-16 89.7 36% NigBI SSNG_07478 Streptomyces sp. C
11
 B1W484_STRGG
(B1W484)		 
[query] 1 - 128 (140)
[subject] 1 - 132 (133)
 8e-16 87   36% Putative ketosteroid isomerase SGR_6072 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
12
 Q6F497_STRGR
(Q6F497)		 
[query] 1 - 128 (140)
[subject] 1 - 132 (133)
 8e-16 87   36% Putative ketosteroid isomerase orf2-AdBS4 Streptomyces griseus
13
 Q1MX77_9ACTO
(Q1MX77)		 Jump to Tetrn_00120 
[query] 1 - 123 (140)
[subject] 1 - 128 (141)
 1e-14 83.6 35% Probable epoxide hydrolase tmnB Streptomyces sp. NRRL 11266
14
 Q27W61_STRVO
(Q27W61)		 Jump to Niger_00140 
[query] 1 - 123 (140)
[subject] 1 - 143 (145)
 3e-14 82   30% NigBI Streptomyces violaceoniger
15
 E0KCN5_STRVO
(E0KCN5)		 
[query] 1 - 121 (140)
[subject] 1 - 141 (145)
 3e-14 82   32% Nuclear transport factor 2 StrviDRAFT_0010 Streptomyces violaceusniger Tu 4113
16
 A4FI35_SACEN
(A4FI35)		 
[query] 1 - 121 (140)
[subject] 1 - 123 (124)
 6e-13 77.8 37% Steroid delta-isomerase SACE_4441 Saccharopolyspora erythraea (strain NRRL 23338) 5.3.3.1
17
 Q846W7_STRCM
(Q846W7)		 Jump to Monen_00240 
[query] 3 - 123 (140)
[subject] 2 - 142 (144)
 7e-13 77.4 33% Probable monensin biosynthesis isomerase monBI Streptomyces cinnamonensis
18
 D7CC05_STRBB
(D7CC05)		 
[query] 1 - 125 (140)
[subject] 1 - 148 (150)
 9e-12 73.9 29% Putative uncharacterized protein SBI_01379 Streptomyces bingchenggensis (strain BCW-1)
19
 C5HV18_STRAT
(C5HV18)		 Jump to Indano_00200 
[query] 3 - 122 (140)
[subject] 2422 - 2546 (2547)
 3e-10 68.9 29% Polyketide synthase idmP Streptomyces antibioticus
20
 Q0K3M5_CUPNH
(Q0K3M5)		 
[query] 1 - 121 (140)
[subject] 1 - 122 (125)
 3e-10 68.6 35% Steroid delta-isomerase H16_B0602 Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Ralstonia eutropha		 5.3.3.1
21
 F8GQY7_CUPNE
(F8GQY7)		 
[query] 1 - 121 (140)
[subject] 1 - 122 (125)
 5e-10 68.2 35% Steroid delta-isomerase CNE_2c05470 Cupriavidus necator N-1 5.3.3.1
22
 D9W5P2_9ACTO
(D9W5P2)		 
[query] 1 - 121 (140)
[subject] 43 - 168 (170)
 8e-10 67.4 30% Predicted protein SSNG_07472 Streptomyces sp. C
23
 Q471Q2_CUPPJ
(Q471Q2)		 
[query] 1 - 121 (140)
[subject] 2 - 123 (126)
 1e-09 66.6 34% Nuclear transport factor 2 Reut_A1514 Cupriavidus pinatubonensis (strain JMP134 / LMG 1197)
Alcaligenes eutrophus
Ralstonia eutropha
24
 B2AIK2_CUPTR
(B2AIK2)		 
[query] 8 - 121 (140)
[subject] 2 - 116 (119)
 5e-08 61.2 34% Steroid delta-isomerase RALTA_B0406 Cupriavidus taiwanensis (strain R1 / LMG 19424)
Ralstonia taiwanensis (strain LMG 19424)		 5.3.3.1
25
 SDIS_PSEPU
(P07445)		 
[query] 1 - 126 (140)
[subject] 3 - 130 (131)
 6e-07 57.8 23% Steroid Delta-isomerase
Delta(5)-3-ketosteroid isomerase		 ksi Pseudomonas putida
Arthrobacter siderocapsulatus		 5.3.3.1
26
 A8H4K7_SHEPA
(A8H4K7)		 
[query] 13 - 122 (140)
[subject] 13 - 121 (123)
 1e-06 57   27% Nuclear transport factor 2 Spea_2174 Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)
27
 B0TTY6_SHEHH
(B0TTY6)		 
[query] 13 - 127 (140)
[subject] 13 - 127 (131)
 1e-05 53.1 24% Nuclear transport factor 2 Shal_2145 Shewanella halifaxensis (strain HAW-EB4)
28
 C5NS17_PSERE
(C5NS17)		 
[query] 8 - 122 (140)
[subject] 8 - 124 (129)
 2e-05 52.4 27% 3-ketosteroid-5-isomerase ORF24 Pseudomonas resinovorans
29
 Q8ETH3_OCEIH
(Q8ETH3)		 
[query] 1 - 121 (140)
[subject] 1 - 122 (124)
 3e-05 52.4 27% Steroid delta-isomerase OB0288 Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) 5.3.3.1
30
 A4XEU5_NOVAD
(A4XEU5)		 
[query] 2 - 121 (140)
[subject] 5 - 125 (128)
 0.0003 48.5 31% Nuclear transport factor 2 Saro_3596 Novosphingobium aromaticivorans (strain DSM 12444)
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q846W8_STRCM
(Q846W8)		 
[query] 1 - 140 (140)
[subject] 1 - 140 (140)
 4e-74 280   100%
Product
Probable monensin biosynthesis isomerase
Gene
monBII
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 12940979 [Medline] 22823264
Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003]
2uniprot
The gene cluster for monensin biosynthesis. [1999]
2
 Q27W62_STRVO
(Q27W62)		 Jump to Niger_00130 
[query] 1 - 125 (140)
[subject] 1 - 125 (155)
 2e-36 155   57%
Product
NigBIII
Gene
 
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17584617
Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007]
4
 D7BSM4_STRBB
(D7BSM4)		 
[query] 2 - 136 (140)
[subject] 160 - 291 (313)
(2 hsp)		 2e-21 105   44%
Product
Putative ketosteroid isomerase
Gene
nanI
SBI_08403
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
5
 Q7WTD9_9ACTO
(Q7WTD9)		 Jump to Nanch_00240 
[query] 2 - 136 (140)
[subject] 160 - 291 (313)
(2 hsp)		 3e-21 105   44%
Product
NanI
Gene
nanI
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12770825 [Medline] 22654646
A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003]
7
 B6ZK72_STRLS
(B6ZK72)		 Jump to Lasal_00210 
[query] 1 - 122 (140)
[subject] 1 - 127 (282)
(2 hsp)		 4e-17 91.3 42%
Product
Epoxide hydrolase
Gene
lsd19
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]
11
 B1W484_STRGG
(B1W484)		 
[query] 1 - 128 (140)
[subject] 1 - 132 (133)
 8e-16 87   36%
Product
Putative ketosteroid isomerase
Gene
SGR_6072
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
12
 Q6F497_STRGR
(Q6F497)		 
[query] 1 - 128 (140)
[subject] 1 - 132 (133)
 8e-16 87   36%
Product
Putative ketosteroid isomerase
Gene
orf2-AdBS4
Organism
Streptomyces griseus
1uniprot[Pubmed] 15228534
DNA-binding specificity of AdpA, a transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus.(Mol. Microbiol.) [2004]
14
 Q27W61_STRVO
(Q27W61)		 Jump to Niger_00140 
[query] 1 - 123 (140)
[subject] 1 - 143 (145)
 3e-14 82   30%
Product
NigBI
Gene
 
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17584617
Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007]
16
 A4FI35_SACEN
(A4FI35)		 
[query] 1 - 121 (140)
[subject] 1 - 123 (124)
 6e-13 77.8 37%
Product
Steroid delta-isomerase
Gene
SACE_4441
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
17
 Q846W7_STRCM
(Q846W7)		 Jump to Monen_00240 
[query] 3 - 123 (140)
[subject] 2 - 142 (144)
 7e-13 77.4 33%
Product
Probable monensin biosynthesis isomerase
Gene
monBI
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 12940979 [Medline] 22823264
Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003]
2uniprot
The gene cluster for monensin biosynthesis. [1999]
18
 D7CC05_STRBB
(D7CC05)		 
[query] 1 - 125 (140)
[subject] 1 - 148 (150)
 9e-12 73.9 29%
Product
Putative uncharacterized protein
Gene
SBI_01379
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
19
 C5HV18_STRAT
(C5HV18)		 Jump to Indano_00200 
[query] 3 - 122 (140)
[subject] 2422 - 2546 (2547)
 3e-10 68.9 29%
Product
Polyketide synthase
Gene
idmP
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
20
 Q0K3M5_CUPNH
(Q0K3M5)		 
[query] 1 - 121 (140)
[subject] 1 - 122 (125)
 3e-10 68.6 35%
Product
Steroid delta-isomerase
Gene
H16_B0602
Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Ralstonia eutropha
1uniprot[Pubmed] 16964242
Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia eutropha H16.(Nat. Biotechnol.) [2006]
24
 B2AIK2_CUPTR
(B2AIK2)		 
[query] 8 - 121 (140)
[subject] 2 - 116 (119)
 5e-08 61.2 34%
Product
Steroid delta-isomerase
Gene
RALTA_B0406
Organism
Cupriavidus taiwanensis (strain R1 / LMG 19424)
Ralstonia taiwanensis (strain LMG 19424)
1uniprot[Pubmed] 18490699
Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and comparative genomics of rhizobia.(Genome Res.) [2008]
25
 SDIS_PSEPU
(P07445)		 
[query] 1 - 126 (140)
[subject] 3 - 130 (131)
 6e-07 57.8 23%
Product
Steroid Delta-isomerase
Delta(5)-3-ketosteroid isomerase
Gene
ksi
Organism
Pseudomonas putida
Arthrobacter siderocapsulatus
1uniprot[Pubmed] 7961420 [Medline] 95050228
Cloning, nucleotide sequence, and overexpression of the gene coding for delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.(J. Bacteriol.) [1994]
2uniprot[Pubmed] 3700400 [Medline] 86196068
The amino acid sequence of a delta 5-3-oxosteroid isomerase from Pseudomonas putida biotype B.(J. Biol. Chem.) [1986]
3uniprot[Pubmed] 9369474 [Medline] 98039133
High-resolution crystal structures of delta5-3-ketosteroid isomerase with and without a reaction intermediate analogue.(Biochemistry) [1997]
4uniprot[Pubmed] 10529226
Roles of active site aromatic residues in catalysis by ketosteroid isomerase from Pseudomonas putida biotype B.(Biochemistry) [1999]
5uniprot[Pubmed] 10653633
Asp-99 donates a hydrogen bond not to Tyr-14 but to the steroid directly in the catalytic mechanism of delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.(Biochemistry) [2000]
6uniprot[Pubmed] 11007792
Detection of large pKa perturbations of an inhibitor and a catalytic group at an enzyme active site, a mechanistic basis for catalytic power of many enzymes.(J. Biol. Chem.) [2000]
7uniprot[Pubmed] 11695900
Maintenance of alpha-helical structures by phenyl rings in the active-site tyrosine triad contributes to catalysis and stability of ketosteroid isomerase from Pseudomonas putida biotype B.(Biochemistry) [2001]
8uniprot[Pubmed] 15819891
Small exterior hydrophobic cluster contributes to conformational stability and steroid binding in ketosteroid isomerase from Pseudomonas putida biotype B.(FEBS J.) [2005]
[pubmed all]
29
 Q8ETH3_OCEIH
(Q8ETH3)		 
[query] 1 - 121 (140)
[subject] 1 - 122 (124)
 3e-05 52.4 27%
Product
Steroid delta-isomerase
Gene
OB0288
Organism
Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)
1uniprot[Pubmed] 12235376 [Medline] 22220767
Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments.(Nucleic Acids Res.) [2002]