BLAST table : Monen_00240

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
Q846W7_STRCM
(Q846W7)
[query] 1 - 144 (144)
[subject] 1 - 144 (144)
1e-76 289   100% Probable monensin biosynthesis isomerase monBI Streptomyces cinnamonensis
2
Q27W61_STRVO
(Q27W61)
Jump to Niger_00140
[query] 1 - 144 (144)
[subject] 2 - 145 (145)
6e-37 157   52% NigBI Streptomyces violaceoniger
3
E0KCN5_STRVO
(E0KCN5)
[query] 1 - 144 (144)
[subject] 2 - 145 (145)
2e-36 155   51% Nuclear transport factor 2 StrviDRAFT_0010 Streptomyces violaceusniger Tu 4113
4
Q7WTD9_9ACTO
(Q7WTD9)
Jump to Nanch_00240
[query] 1 - 140 (144)
[subject] 2 - 141 (313)
9e-32 140   50% NanI nanI Streptomyces nanchangensis
5
D7BSM4_STRBB
(D7BSM4)
[query] 1 - 140 (144)
[subject] 2 - 141 (313)
2e-31 139   50% Putative ketosteroid isomerase nanI
SBI_08403
Streptomyces bingchenggensis (strain BCW-1)
6
D9W5P7_9ACTO
(D9W5P7)
[query] 1 - 143 (144)
[subject] 2 - 144 (149)
8e-26 120   42% Predicted protein SSNG_07477 Streptomyces sp. C
7
D9W5P8_9ACTO
(D9W5P8)
[query] 1 - 140 (144)
[subject] 98 - 237 (243)
1e-25 119   43% NigBI SSNG_07478 Streptomyces sp. C
8
B6ZK72_STRLS
(B6ZK72)
Jump to Lasal_00210
[query] 2 - 143 (144)
[subject] 135 - 278 (282)
(2 hsp)
5e-24 114   45% Epoxide hydrolase lsd19 Streptomyces lasaliensis
9
B5M9L7_STRLS
(B5M9L7)
Jump to Lasal2_00250
[query] 2 - 143 (144)
[subject] 135 - 278 (282)
(2 hsp)
5e-24 114   45% Epoxide hydrolase lasB Streptomyces lasaliensis
10
E0KCN4_STRVO
(E0KCN4)
[query] 2 - 142 (144)
[subject] 3 - 123 (155)
4e-15 84.7 33% Putative uncharacterized protein StrviDRAFT_0009 Streptomyces violaceusniger Tu 4113
11
D7CC05_STRBB
(D7CC05)
[query] 2 - 143 (144)
[subject] 3 - 147 (150)
1e-14 83.6 34% Putative uncharacterized protein SBI_01379 Streptomyces bingchenggensis (strain BCW-1)
12
Q27W62_STRVO
(Q27W62)
Jump to Niger_00130
[query] 2 - 142 (144)
[subject] 3 - 123 (155)
2e-14 82.8 32% NigBIII Streptomyces violaceoniger
13
D7F1M3_9ACTO
(D7F1M3)
[query] 2 - 142 (144)
[subject] 3 - 128 (139)
1e-13 80.1 34% Epoxide hydrolase tsnB Streptomyces longisporoflavus
14
B1W484_STRGG
(B1W484)
[query] 1 - 144 (144)
[subject] 2 - 132 (133)
4e-13 78.2 30% Putative ketosteroid isomerase SGR_6072 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
15
Q6F497_STRGR
(Q6F497)
[query] 1 - 144 (144)
[subject] 2 - 132 (133)
4e-13 78.2 30% Putative ketosteroid isomerase orf2-AdBS4 Streptomyces griseus
16
Q846W8_STRCM
(Q846W8)
Jump to Monen_00230
[query] 2 - 142 (144)
[subject] 3 - 123 (140)
1e-11 73.6 31% Probable monensin biosynthesis isomerase monBII Streptomyces cinnamonensis
17
C5HV18_STRAT
(C5HV18)
Jump to Indano_00200
[query] 1 - 140 (144)
[subject] 2421 - 2545 (2547)
1e-11 73.2 31% Polyketide synthase idmP Streptomyces antibioticus
18
D9W5P2_9ACTO
(D9W5P2)
[query] 1 - 142 (144)
[subject] 44 - 170 (170)
3e-11 72   29% Predicted protein SSNG_07472 Streptomyces sp. C
19
Q1MX77_9ACTO
(Q1MX77)
Jump to Tetrn_00120
[query] 1 - 142 (144)
[subject] 2 - 128 (141)
4e-11 71.6 32% Probable epoxide hydrolase tmnB Streptomyces sp. NRRL 11266
20
A4FI35_SACEN
(A4FI35)
[query] 2 - 140 (144)
[subject] 3 - 123 (124)
8e-10 67   31% Steroid delta-isomerase SACE_4441 Saccharopolyspora erythraea (strain NRRL 23338) 5.3.3.1
21
F6EPH3_9MYCO
(F6EPH3)
[query] 12 - 142 (144)
[subject] 13 - 122 (123)
1e-06 57   29% Putative 3-ketosteroid 5-isomerase AS9A_0954 Amycolicicoccus subflavus DQS3-9A1
22
Q471Q2_CUPPJ
(Q471Q2)
[query] 6 - 140 (144)
[subject] 8 - 123 (126)
2e-06 56.2 32% Nuclear transport factor 2 Reut_A1514 Cupriavidus pinatubonensis (strain JMP134 / LMG 1197)
Alcaligenes eutrophus
Ralstonia eutropha
23
SDIS_PSEPU
(P07445)
[query] 17 - 142 (144)
[subject] 20 - 127 (131)
4e-06 55.1 29% Steroid Delta-isomerase
Delta(5)-3-ketosteroid isomerase
ksi Pseudomonas putida
Arthrobacter siderocapsulatus
5.3.3.1
24
A4XEU5_NOVAD
(A4XEU5)
[query] 16 - 140 (144)
[subject] 20 - 125 (128)
4e-06 55.1 31% Nuclear transport factor 2 Saro_3596 Novosphingobium aromaticivorans (strain DSM 12444)
25
F8GQY7_CUPNE
(F8GQY7)
[query] 5 - 143 (144)
[subject] 6 - 125 (125)
4e-06 55.1 32% Steroid delta-isomerase CNE_2c05470 Cupriavidus necator N-1 5.3.3.1
26
Q0K3M5_CUPNH
(Q0K3M5)
[query] 5 - 143 (144)
[subject] 6 - 125 (125)
7e-06 54.3 30% Steroid delta-isomerase H16_B0602 Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Ralstonia eutropha
5.3.3.1
27
C5NS17_PSERE
(C5NS17)
[query] 17 - 141 (144)
[subject] 18 - 124 (129)
1e-05 53.1 29% 3-ketosteroid-5-isomerase ORF24 Pseudomonas resinovorans
28
Q6SH72_9BACT
(Q6SH72)
[query] 1 - 140 (144)
[subject] 1 - 121 (125)
3e-05 52   28% Steroid delta-isomerase ksi
MBMO_EBAC000-63A02.25
uncultured marine bacterium 442 5.3.3.1
29
A0Z4P3_9GAMM
(A0Z4P3)
[query] 1 - 140 (144)
[subject] 1 - 121 (125)
3e-05 52   28% Nuclear transport factor 2 MGP2080_10543 marine gamma proteobacterium HTCC2080
30
B2AIK2_CUPTR
(B2AIK2)
[query] 7 - 140 (144)
[subject] 2 - 116 (119)
9e-05 50.4 31% Steroid delta-isomerase RALTA_B0406 Cupriavidus taiwanensis (strain R1 / LMG 19424)
Ralstonia taiwanensis (strain LMG 19424)
5.3.3.1
31
B7X4V2_COMTE
(B7X4V2)
[query] 17 - 54 (144)
[subject] 18 - 55 (125)
0.0001 50.1 58% Steroid Delta-isomerase CtesDRAFT_PD3678 Comamonas testosteroni KF-1 5.3.3.1
32
D0J389_COMT2
(D0J389)
[query] 17 - 70 (144)
[subject] 12 - 65 (119)
0.0002 48.9 48% Putative uncharacterized protein CtCNB1_1323 Comamonas testosteroni (strain CNB-2)
33
E0D2V1_COMTE
(E0D2V1)
[query] 17 - 54 (144)
[subject] 18 - 55 (125)
0.0003 48.5 58% 3-ketosteroiod isomerase Comamonas testosteroni
Pseudomonas testosteroni
34
Q73X32_MYCPA
(Q73X32)
[query] 17 - 143 (144)
[subject] 18 - 123 (123)
0.0003 48.5 29% Putative uncharacterized protein MAP_2478 Mycobacterium paratuberculosis
35
F7P514_MYCPA
(F7P514)
[query] 17 - 143 (144)
[subject] 18 - 123 (123)
0.0003 48.5 29% NTF2 domain-containing protein MAPs_35910 Mycobacterium avium subsp. paratuberculosis S397
36
A5VBH5_SPHWW
(A5VBH5)
[query] 9 - 79 (144)
[subject] 9 - 82 (122)
0.0004 48.5 39% Nuclear transport factor 2 Swit_3295 Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
37
D8DDX1_COMTE
(D8DDX1)
[query] 17 - 70 (144)
[subject] 12 - 65 (119)
0.0005 47.8 48% Putative uncharacterized protein CTS44_25169 Comamonas testosteroni S44
38
Q5Z059_NOCFA
(Q5Z059)
[query] 17 - 136 (144)
[subject] 16 - 116 (126)
0.0006 47.8 26% Putative 3-ketosteroid-5-isomerase NFA_13370 Nocardia farcinica
39
SDIS_COMTE
(P00947)
[query] 17 - 54 (144)
[subject] 18 - 55 (125)
0.0008 47.4 55% Steroid Delta-isomerase
Delta(5)-3-ketosteroid isomerase
ksi Comamonas testosteroni
Pseudomonas testosteroni
5.3.3.1
40
A0QCP8_MYCA1
(A0QCP8)
[query] 17 - 143 (144)
[subject] 18 - 123 (123)
0.0009 47.4 29% Steroid delta-isomerase MAV_1444 Mycobacterium avium (strain 104) 5.3.3.1
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
Q846W7_STRCM
(Q846W7)
[query] 1 - 144 (144)
[subject] 1 - 144 (144)
1e-76 289   100%
Product
Probable monensin biosynthesis isomerase
Gene
monBI
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 12940979 [Medline] 22823264
Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003]
2uniprot
The gene cluster for monensin biosynthesis. [1999]
2
Q27W61_STRVO
(Q27W61)
Jump to Niger_00140
[query] 1 - 144 (144)
[subject] 2 - 145 (145)
6e-37 157   52%
Product
NigBI
Gene
 
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17584617
Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007]
4
Q7WTD9_9ACTO
(Q7WTD9)
Jump to Nanch_00240
[query] 1 - 140 (144)
[subject] 2 - 141 (313)
9e-32 140   50%
Product
NanI
Gene
nanI
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12770825 [Medline] 22654646
A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003]
5
D7BSM4_STRBB
(D7BSM4)
[query] 1 - 140 (144)
[subject] 2 - 141 (313)
2e-31 139   50%
Product
Putative ketosteroid isomerase
Gene
nanI
SBI_08403
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
8
B6ZK72_STRLS
(B6ZK72)
Jump to Lasal_00210
[query] 2 - 143 (144)
[subject] 135 - 278 (282)
(2 hsp)
5e-24 114   45%
Product
Epoxide hydrolase
Gene
lsd19
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]
11
D7CC05_STRBB
(D7CC05)
[query] 2 - 143 (144)
[subject] 3 - 147 (150)
1e-14 83.6 34%
Product
Putative uncharacterized protein
Gene
SBI_01379
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
12
Q27W62_STRVO
(Q27W62)
Jump to Niger_00130
[query] 2 - 142 (144)
[subject] 3 - 123 (155)
2e-14 82.8 32%
Product
NigBIII
Gene
 
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17584617
Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007]
14
B1W484_STRGG
(B1W484)
[query] 1 - 144 (144)
[subject] 2 - 132 (133)
4e-13 78.2 30%
Product
Putative ketosteroid isomerase
Gene
SGR_6072
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
15
Q6F497_STRGR
(Q6F497)
[query] 1 - 144 (144)
[subject] 2 - 132 (133)
4e-13 78.2 30%
Product
Putative ketosteroid isomerase
Gene
orf2-AdBS4
Organism
Streptomyces griseus
1uniprot[Pubmed] 15228534
DNA-binding specificity of AdpA, a transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus.(Mol. Microbiol.) [2004]
16
Q846W8_STRCM
(Q846W8)
Jump to Monen_00230
[query] 2 - 142 (144)
[subject] 3 - 123 (140)
1e-11 73.6 31%
Product
Probable monensin biosynthesis isomerase
Gene
monBII
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 12940979 [Medline] 22823264
Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003]
2uniprot
The gene cluster for monensin biosynthesis. [1999]
17
C5HV18_STRAT
(C5HV18)
Jump to Indano_00200
[query] 1 - 140 (144)
[subject] 2421 - 2545 (2547)
1e-11 73.2 31%
Product
Polyketide synthase
Gene
idmP
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
20
A4FI35_SACEN
(A4FI35)
[query] 2 - 140 (144)
[subject] 3 - 123 (124)
8e-10 67   31%
Product
Steroid delta-isomerase
Gene
SACE_4441
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
23
SDIS_PSEPU
(P07445)
[query] 17 - 142 (144)
[subject] 20 - 127 (131)
4e-06 55.1 29%
Product
Steroid Delta-isomerase
Delta(5)-3-ketosteroid isomerase
Gene
ksi
Organism
Pseudomonas putida
Arthrobacter siderocapsulatus
1uniprot[Pubmed] 7961420 [Medline] 95050228
Cloning, nucleotide sequence, and overexpression of the gene coding for delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.(J. Bacteriol.) [1994]
2uniprot[Pubmed] 3700400 [Medline] 86196068
The amino acid sequence of a delta 5-3-oxosteroid isomerase from Pseudomonas putida biotype B.(J. Biol. Chem.) [1986]
3uniprot[Pubmed] 9369474 [Medline] 98039133
High-resolution crystal structures of delta5-3-ketosteroid isomerase with and without a reaction intermediate analogue.(Biochemistry) [1997]
4uniprot[Pubmed] 10529226
Roles of active site aromatic residues in catalysis by ketosteroid isomerase from Pseudomonas putida biotype B.(Biochemistry) [1999]
5uniprot[Pubmed] 10653633
Asp-99 donates a hydrogen bond not to Tyr-14 but to the steroid directly in the catalytic mechanism of delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.(Biochemistry) [2000]
6uniprot[Pubmed] 11007792
Detection of large pKa perturbations of an inhibitor and a catalytic group at an enzyme active site, a mechanistic basis for catalytic power of many enzymes.(J. Biol. Chem.) [2000]
7uniprot[Pubmed] 11695900
Maintenance of alpha-helical structures by phenyl rings in the active-site tyrosine triad contributes to catalysis and stability of ketosteroid isomerase from Pseudomonas putida biotype B.(Biochemistry) [2001]
8uniprot[Pubmed] 15819891
Small exterior hydrophobic cluster contributes to conformational stability and steroid binding in ketosteroid isomerase from Pseudomonas putida biotype B.(FEBS J.) [2005]
[pubmed all]
26
Q0K3M5_CUPNH
(Q0K3M5)
[query] 5 - 143 (144)
[subject] 6 - 125 (125)
7e-06 54.3 30%
Product
Steroid delta-isomerase
Gene
H16_B0602
Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Ralstonia eutropha
1uniprot[Pubmed] 16964242
Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia eutropha H16.(Nat. Biotechnol.) [2006]
29
A0Z4P3_9GAMM
(A0Z4P3)
[query] 1 - 140 (144)
[subject] 1 - 121 (125)
3e-05 52   28%
Product
Nuclear transport factor 2
Gene
MGP2080_10543
Organism
marine gamma proteobacterium HTCC2080
1uniprot[Pubmed] 20472793
Genome sequences of strains HTCC2148 and HTCC2080, belonging to the OM60/NOR5 clade of the Gammaproteobacteria.(J. Bacteriol.) [2010]
30
B2AIK2_CUPTR
(B2AIK2)
[query] 7 - 140 (144)
[subject] 2 - 116 (119)
9e-05 50.4 31%
Product
Steroid delta-isomerase
Gene
RALTA_B0406
Organism
Cupriavidus taiwanensis (strain R1 / LMG 19424)
Ralstonia taiwanensis (strain LMG 19424)
1uniprot[Pubmed] 18490699
Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and comparative genomics of rhizobia.(Genome Res.) [2008]
31
B7X4V2_COMTE
(B7X4V2)
[query] 17 - 54 (144)
[subject] 18 - 55 (125)
0.0001 50.1 58%
Product
Steroid Delta-isomerase
Gene
CtesDRAFT_PD3678
Organism
Comamonas testosteroni KF-1
1uniprot[Pubmed] 15240283
Mineralization of individual congeners of linear alkylbenzenesulfonate by defined pairs of heterotrophic bacteria.(Appl. Environ. Microbiol.) [2004]
32
D0J389_COMT2
(D0J389)
[query] 17 - 70 (144)
[subject] 12 - 65 (119)
0.0002 48.9 48%
Product
Putative uncharacterized protein
Gene
CtCNB1_1323
Organism
Comamonas testosteroni (strain CNB-2)
1uniprot[Pubmed] 19734336
The complete genome of Comamonas testosteroni reveals its genetic adaptations to changing environments.(Appl. Environ. Microbiol.) [2009]
34
Q73X32_MYCPA
(Q73X32)
[query] 17 - 143 (144)
[subject] 18 - 123 (123)
0.0003 48.5 29%
Product
Putative uncharacterized protein
Gene
MAP_2478
Organism
Mycobacterium paratuberculosis
1uniprot[Pubmed] 16116077
The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005]
38
Q5Z059_NOCFA
(Q5Z059)
[query] 17 - 136 (144)
[subject] 16 - 116 (126)
0.0006 47.8 26%
Product
Putative 3-ketosteroid-5-isomerase
Gene
NFA_13370
Organism
Nocardia farcinica
1uniprot[Pubmed] 15466710
The complete genomic sequence of Nocardia farcinica IFM 10152.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
39
SDIS_COMTE
(P00947)
[query] 17 - 54 (144)
[subject] 18 - 55 (125)
0.0008 47.4 55%
Product
Steroid Delta-isomerase
Delta(5)-3-ketosteroid isomerase
Gene
ksi
Organism
Comamonas testosteroni
Pseudomonas testosteroni
1uniprot[Pubmed] 3224818 [Medline] 89137982
Nucleotide sequence of the gene for the delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni.(Gene) [1988]
2uniprot[Pubmed] 3480517 [Medline] 88097394
Isolation and sequencing of the gene encoding delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni: overexpression of the protein.(Proc. Natl. Acad. Sci. U.S.A.) [1987]
3uniprot[Pubmed] 5135313 [Medline] 72085988
The amino acid sequence of delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni.(J. Biol. Chem.) [1971]
4uniprot[Pubmed] 4753764 [Medline] 74032505
Molecular weight determination and structural studies of Pseudomonas testosteroni delta 5 leads to 4-3-oxosteroid isomerase (EC 5.3.3.1).(FEBS Lett.) [1973]
5uniprot[Pubmed] 9369474 [Medline] 98039133
High-resolution crystal structures of delta5-3-ketosteroid isomerase with and without a reaction intermediate analogue.(Biochemistry) [1997]
6uniprot[Pubmed] 9103200 [Medline] 97258944
Solution structure of 3-oxo-delta5-steroid isomerase.(Science) [1997]
7uniprot[Pubmed] 9778345
Solution structure of delta 5-3-ketosteroid isomerase complexed with the steroid 19-nortestosterone hemisuccinate.(Biochemistry) [1998]
8uniprot[Pubmed] 10551849 [Medline] 20020257
Crystal structure of delta(5)-3-ketosteroid isomerase from Pseudomonas testosteroni in complex with equilenin settles the correct hydrogen bonding scheme for transition state stabilization.(J. Biol. Chem.) [1999]
9uniprot[Pubmed] 12852789
The conserved cis-Pro39 residue plays a crucial role in the proper positioning of the catalytic base Asp38 in ketosteroid isomerase from Comamonas testosteroni.(Biochem. J.) [2003]
10uniprot[Pubmed] 12734184
Origin of the different pH activity profile in two homologous ketosteroid isomerases.(J. Biol. Chem.) [2003]
[pubmed all]