BLAST table : Rifam_00550

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 O52569_AMYMD
(O52569)		 
[query] 1 - 422 (422)
[subject] 1 - 422 (422)
 0.0 855   100% Putative cytochrome P450 monooxygenase Amycolatopsis mediterranei
Nocardia mediterranei
2
 D8HZB4_AMYMU
(D8HZB4)		 
[query] 1 - 422 (422)
[subject] 3 - 424 (424)
 0.0 852   100% Cytochrome P450 AMED_0649 Amycolatopsis mediterranei (strain U-32)
3
 A8M6D9_SALAI
(A8M6D9)		 
[query] 12 - 422 (422)
[subject] 12 - 422 (422)
 0.0 691   80% Cytochrome P450 Sare_1259 Salinispora arenicola (strain CNS-205)
4
 D8HZA2_AMYMU
(D8HZA2)		 
[query] 1 - 422 (422)
[subject] 1 - 417 (421)
 1e-168 594   67% Cytochrome P450 AMED_0637 Amycolatopsis mediterranei (strain U-32)
5
 O52561_AMYMD
(O52561)		 Jump to Rifam_00410 
[query] 1 - 422 (422)
[subject] 1 - 417 (421)
 1e-168 594   67% Putative cytochrome P450 monooxygenase Amycolatopsis mediterranei
Nocardia mediterranei
6
 F4CKU2_9PSEU
(F4CKU2)		 
[query] 12 - 422 (422)
[subject] 3 - 413 (413)
 1e-104 382   50% Linalool 8-monooxygenase Psed_1700 Pseudonocardia dioxanivorans CB1190 1.14.99.28
7
 D6Y2H2_THEBD
(D6Y2H2)		 
[query] 11 - 422 (422)
[subject] 9 - 422 (423)
 1e-87 328   46% Cytochrome P450 Tbis_2110 Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 / R51)
8
 Q595U3_9ACTO
(Q595U3)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 9e-87 325   43% Cytochrome P450 monooxygenase CYP107Z9 ema12 Streptomyces tubercidicus
9
 Q595V0_9ACTO
(Q595V0)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (432)
 1e-84 318   42% Cytochrome P450 monooxygenase CYP107Z6 ema5 Streptomyces sp. I-1525
10
 Q595U4_STRRY
(Q595U4)		 
[query] 13 - 421 (422)
[subject] 61 - 471 (475)
 6e-84 316   43% Cytochrome P450 monooxygenase CYP107Z1 ema11 Streptomyces rimosus subsp. paromomycinus
11
 Q595T8_9ACTO
(Q595T8)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 6e-84 316   42% Cytochrome P450 monooxygenase CYP107Z7 ema17 Streptomyces tubercidicus
12
 Q595T9_9ACTO
(Q595T9)		 
[query] 14 - 422 (422)
[subject] 22 - 430 (430)
 7e-84 315   43% Cytochrome P450 monooxygenase CYP107Z4 ema16 Streptomyces lydicus
13
 Q595V2_STRRY
(Q595V2)		 
[query] 13 - 398 (422)
[subject] 56 - 440 (470)
 2e-83 314   44% Cytochrome P450 monooxygenase CYP107Z2v2 ema3 Streptomyces rimosus subsp. paromomycinus
14
 Q595U7_9ACTO
(Q595U7)		 
[query] 13 - 398 (422)
[subject] 61 - 445 (475)
 5e-83 313   44% Cytochrome P450 monooxygenase CYP107Z2v1 ema8 Streptomyces albofaciens
15
 Q595U9_9ACTO
(Q595U9)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 5e-83 313   42% Cytochrome P450 monooxygenase CYP107Z5v2 Ema6 Streptomyces saraceticus
16
 Q595U2_STRPT
(Q595U2)		 
[query] 13 - 421 (422)
[subject] 21 - 429 (430)
 5e-83 313   41% Cytochrome P450 monooxygenase CYP107Z8 ema13 Streptomyces platensis
17
 Q595U0_9ACTO
(Q595U0)		 
[query] 13 - 421 (422)
[subject] 21 - 429 (430)
 1e-82 311   42% Cytochrome P450 monooxygenase CYP107Z5v1 em15 Streptomyces lydicus
18
 Q595V1_9ACTO
(Q595V1)		 
[query] 13 - 421 (422)
[subject] 21 - 429 (430)
 2e-82 311   42% Cytochrome P450 monooxygenase CYP107Z5v3 ema4 Streptomyces lydicus
19
 Q595U5_STRKA
(Q595U5)		 
[query] 13 - 421 (422)
[subject] 21 - 429 (430)
 2e-82 311   42% Cytochrome P450 monooxygenase CYP107Z5v3 ema10 Streptomyces kasugaensis
20
 Q60005_STRTH
(Q60005)		 
[query] 12 - 421 (422)
[subject] 4 - 411 (411)
 2e-80 304   42% Putative cytochrome P-450 protein Streptomyces thermotolerans
21
 Q595U8_9ACTO
(Q595U8)		 
[query] 13 - 421 (422)
[subject] 21 - 428 (429)
 4e-80 303   41% Cytochrome P450 monooxygenase CYP107Z3 ema7 Streptomyces sp. IHS-0435
22
 Q595V6_9ACTO
(Q595V6)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 3e-79 300   40% Cytochrome P450 monooxygenase CYP107Z12 ema1 Streptomyces tubercidicus
23
 Q595U6_STRPT
(Q595U6)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 4e-79 300   40% Cytochrome P450 monooxygenase CYP107Z11 ema9 Streptomyces platensis
24
 Q595V3_9ACTO
(Q595V3)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 2e-77 294   40% Cytochrome P450 monooxygenase CYP107Z10 ema2 Streptomyces tubercidicus
25
 Q595U1_STRPT
(Q595U1)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 2e-77 294   40% Cytochrome P450 monooxygenase CYP107Z10 ema14 Streptomyces platensis
26
 A8M6V8_SALAI
(A8M6V8)		 
[query] 16 - 421 (422)
[subject] 18 - 420 (420)
 4e-73 280   39% Cytochrome P450 Sare_4557 Salinispora arenicola (strain CNS-205)
27
 D7AYD4_NOCDD
(D7AYD4)		 
[query] 1 - 421 (422)
[subject] 1 - 421 (421)
 5e-72 276   39% Cytochrome P450 Ndas_0674 Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
28
 CPXJ_SACEN
(Q00441)		 
[query] 13 - 421 (422)
[subject] 6 - 402 (404)
 9e-71 272   40% 6-deoxyerythronolide B hydroxylase
CYPCVIIA1
Cytochrome P450 107A1
Cytochrome P450eryF
Erythomycin A biosynthesis hydrolase		 eryF
CYP107A1
SACE_0730		 Saccharopolyspora erythraea (strain NRRL 23338) 1.14.-.-
29
 A4FLS3_SACEN
(A4FLS3)		 
[query] 15 - 420 (422)
[subject] 12 - 402 (405)
 2e-69 267   41% Cytochrome P450-like enzyme cypA
SACE_5814		 Saccharopolyspora erythraea (strain NRRL 23338) 1.14.-.-
30
 CPXK_SACEN
(P33271)		 
[query] 15 - 420 (422)
[subject] 12 - 402 (405)
 2e-69 267   41% Cytochrome P450 107B1
Cytochrome P450CVIIB1		 CYP107B1 Saccharopolyspora erythraea (strain NRRL 23338) 1.14.-.-
31
 E8U935_DEIML
(E8U935)		 
[query] 14 - 405 (422)
[subject] 9 - 389 (405)
 3e-68 263   39% Peroxidase Deima_1929 Deinococcus maricopensis (strain DSM 21211 / LMG 22137 / NRRL B-23946 / LB-34) 1.11.1.7
32
 D8HTB4_AMYMU
(D8HTB4)		 
[query] 20 - 421 (422)
[subject] 9 - 403 (403)
 2e-67 261   42% Cytochrome P450 AMED_2213 Amycolatopsis mediterranei (strain U-32)
33
 D5E3H2_BACMQ
(D5E3H2)		 
[query] 13 - 405 (422)
[subject] 8 - 395 (410)
 7e-67 259   39% Cytochrome P450 BMQ_pBM50008 Bacillus megaterium (strain ATCC 12872 / QMB1551) 1.14.-.-
34
 C3BML3_9BACI
(C3BML3)		 
[query] 13 - 419 (422)
[subject] 8 - 408 (410)
 1e-66 258   39% Cytochrome p450 bpmyx0001_29010 Bacillus pseudomycoides DSM 12442
35
 C3B5N1_BACMY
(C3B5N1)		 
[query] 13 - 419 (422)
[subject] 8 - 408 (410)
 2e-66 258   39% Cytochrome p450 bmyco0003_27790 Bacillus mycoides Rock3-17
36
 C3AN98_BACMY
(C3AN98)		 
[query] 13 - 419 (422)
[subject] 8 - 408 (410)
 2e-66 258   39% Cytochrome p450 bmyco0002_26430 Bacillus mycoides
37
 D2S469_GEOOG
(D2S469)		 
[query] 21 - 421 (422)
[subject] 24 - 411 (412)
 2e-66 257   43% Cytochrome P450 Gobs_2385 Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20)
38
 B5H2T5_STRCL
(B5H2T5)		 
[query] 5 - 420 (422)
[subject] 9 - 420 (421)
 2e-65 254   37% Cytochrome P450 monooxygenase CYP107Z4 SSCG_05864 Streptomyces clavuligerus ATCC 27064
39
 D5SJQ5_STRCL
(D5SJQ5)		 
[query] 5 - 420 (422)
[subject] 54 - 465 (466)
 2e-65 254   37% Cytochrome P450 monooxygenase SCLAV_p0661 Streptomyces clavuligerus ATCC 27064
40
 D1GLU0_9ACTO
(D1GLU0)		 Jump to Strply_00120 
[query] 18 - 422 (422)
[subject] 15 - 410 (413)
 5e-65 253   40% Cytochrome P450 slgO2 Streptomyces lydicus
41
 F3N9Q4_9ACTO
(F3N9Q4)		 
[query] 18 - 402 (422)
[subject] 8 - 373 (399)
 9e-65 252   42% Putative cytochrome P450 SGM_0088 Streptomyces griseoaurantiacus M045
42
 E4NIK6_KITSK
(E4NIK6)		 
[query] 2 - 403 (422)
[subject] 19 - 407 (428)
 2e-64 251   39% Putative cytochrome P450 KSE_70460 Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
43
 D8HWS8_AMYMU
(D8HWS8)		 
[query] 12 - 410 (422)
[subject] 5 - 385 (391)
 3e-64 250   41% Cytochrome P450 AMED_4704 Amycolatopsis mediterranei (strain U-32)
44
 F8JYE6_STRCT
(F8JYE6)		 
[query] 44 - 403 (422)
[subject] 40 - 391 (407)
 2e-63 248   40% 6-deoxyerythronolide B hydroxylase eryF
SCAT_3583		 Streptomyces cattleya 1.14.-.-
45
 B5UYM7_BACCE
(B5UYM7)		 
[query] 13 - 405 (422)
[subject] 8 - 395 (410)
 1e-62 245   37% Cytochrome P450 BCAH1134_C0629 Bacillus cereus AH1134 1.14.-.-
46
 Q83X67_STRRO
(Q83X67)		 
[query] 49 - 413 (422)
[subject] 42 - 394 (404)
 1e-62 245   40% P450 hydroxylase LkmK lkmK Streptomyces rochei
Streptomyces parvullus
47
 C3HA20_BACTU
(C3HA20)		 
[query] 13 - 405 (422)
[subject] 8 - 395 (410)
 1e-62 245   37% Cytochrome p450 bthur0011_53340 Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
48
 B4VB56_9ACTO
(B4VB56)		 
[query] 11 - 421 (422)
[subject] 7 - 402 (406)
 2e-62 244   38% Cytochrome P450 107B1 SSAG_05045 Streptomyces sp. Mg1
49
 Q737F3_BACC1
(Q737F3)		 
[query] 13 - 405 (422)
[subject] 8 - 395 (410)
 2e-62 244   37% Cytochrome p450 cypA
BCE_2696		 Bacillus cereus (strain ATCC 10987)
50
 E0L254_STRVO
(E0L254)		 
[query] 5 - 422 (422)
[subject] 12 - 415 (419)
 4e-62 243   39% Cytochrome P450 StrviDRAFT_8982 Streptomyces violaceusniger Tu 4113
51
 D6TVR9_9CHLR
(D6TVR9)		 
[query] 8 - 405 (422)
[subject] 15 - 399 (415)
 6e-62 243   37% Cytochrome P450 Krac_5329 Ktedonobacter racemifer DSM 44963
52
 D7C4A9_STRBB
(D7C4A9)		 
[query] 17 - 405 (422)
[subject] 13 - 392 (418)
 6e-62 243   39% Cytochrome P450 hydroxylase cyp14
SBI_00810		 Streptomyces bingchenggensis (strain BCW-1)
53
 A8M8D4_SALAI
(A8M8D4)		 
[query] 14 - 421 (422)
[subject] 11 - 406 (408)
 2e-61 241   39% Cytochrome P450 Sare_3149 Salinispora arenicola (strain CNS-205)
54
 D9T183_MICAI
(D9T183)		 
[query] 1 - 412 (422)
[subject] 1 - 401 (412)
 2e-61 241   38% Cytochrome P450 Micau_3886 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
55
 Q5Y9H2_9ACTO
(Q5Y9H2)		 
[query] 13 - 394 (422)
[subject] 9 - 378 (406)
 3e-61 241   41% Cytochrome P450 oxidoreductase eryF Aeromicrobium erythreum
56
 A4F8W1_SACEN
(A4F8W1)		 
[query] 10 - 422 (422)
[subject] 2 - 391 (391)
 3e-61 240   38% Putative cytochrome P450 cyp23
SACE_1158		 Saccharopolyspora erythraea (strain NRRL 23338) 1.14.-.-
57
 D2S3S0_GEOOG
(D2S3S0)		 
[query] 1 - 421 (422)
[subject] 1 - 416 (426)
 4e-61 240   38% Cytochrome P450 Gobs_0142 Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20)
58
 F8AZ18_9ACTO
(F8AZ18)		 
[query] 13 - 406 (422)
[subject] 12 - 392 (411)
 4e-61 240   39% Peroxidase FsymDg_2207 Frankia symbiont of Datisca glomerata 1.11.1.7
59
 D8HNZ6_AMYMU
(D8HNZ6)		 
[query] 8 - 393 (422)
[subject] 2 - 376 (402)
 4e-61 240   39% Cytochrome P450 AMED_3960 Amycolatopsis mediterranei (strain U-32)
60
 Q83X78_STRRO
(Q83X78)		 
[query] 4 - 422 (422)
[subject] 7 - 405 (406)
 5e-61 239   37% P450 hydroxylase LkmF lkmF Streptomyces rochei
Streptomyces parvullus
61
 F4CJI8_9PSEU
(F4CJI8)		 
[query] 14 - 422 (422)
[subject] 18 - 402 (420)
 7e-61 239   40% Linalool 8-monooxygenase Psed_2740 Pseudonocardia dioxanivorans CB1190 1.14.99.28
62
 F4CLB6_9PSEU
(F4CLB6)		 
[query] 49 - 405 (422)
[subject] 42 - 390 (406)
 1e-60 239   40% Peroxidase Psed_3788 Pseudonocardia dioxanivorans CB1190 1.11.1.7
63
 E0KQX0_STRVO
(E0KQX0)		 
[query] 5 - 422 (422)
[subject] 2 - 408 (408)
 1e-60 238   37% Cytochrome P450 StrviDRAFT_5047 Streptomyces violaceusniger Tu 4113
64
 F2QB25_STRPT
(F2QB25)		 
[query] 15 - 405 (422)
[subject] 10 - 386 (402)
 2e-60 238   39% Cytochrome P450 monooxygenase p450 Streptomyces platensis 1.14.14.1
65
 E7M9R0_9BACL
(E7M9R0)		 
[query] 11 - 405 (422)
[subject] 9 - 388 (405)
 2e-60 238   35% Cytochrome P450-like protein PL1_2073 Paenibacillus larvae subsp. larvae B-3650
66
 A9AVB8_HERA2
(A9AVB8)		 
[query] 6 - 405 (422)
[subject] 9 - 395 (411)
 3e-60 237   37% Cytochrome P450 Haur_1966 Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785)
67
 F8K4L4_STRCT
(F8K4L4)		 
[query] 17 - 405 (422)
[subject] 31 - 399 (415)
 4e-60 237   38% Cytochrome P450 107B1 CYP107B
SCAT_2817		 Streptomyces cattleya 1.14.-.-
68
 Q09DE5_STIAD
(Q09DE5)		 
[query] 13 - 405 (422)
[subject] 9 - 387 (403)
 5e-60 236   39% Cytochrome P450
Cytochrome P450 107B1		 STAUR_1562
STIAU_1539		 Stigmatella aurantiaca (strain DW4/3-1) 1.14.-.-
69
 A9AXU5_HERA2
(A9AXU5)		 
[query] 13 - 405 (422)
[subject] 8 - 389 (405)
 7e-60 236   36% Cytochrome P450 Haur_2271 Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785)
70
 D9VGH4_9ACTO
(D9VGH4)		 
[query] 26 - 410 (422)
[subject] 24 - 393 (409)
 8e-60 236   38% RubU protein SSMG_01749 Streptomyces sp. AA4
71
 D9XPH0_9ACTO
(D9XPH0)		 
[query] 3 - 422 (422)
[subject] 2 - 405 (409)
 8e-60 236   37% Cytochrome P450 107B1 SSRG_06286 Streptomyces griseoflavus Tu4000
72
 A4F9M3_SACEN
(A4F9M3)		 
[query] 22 - 405 (422)
[subject] 18 - 379 (398)
 1e-59 235   39% Cytochrome P450-like enzyme cypA
SACE_1426		 Saccharopolyspora erythraea (strain NRRL 23338) 1.14.-.-
73
 B5H3V7_STRCL
(B5H3V7)		 
[query] 16 - 421 (422)
[subject] 19 - 413 (418)
 1e-59 235   38% Cytochrome P450 monooxygenase 107L14
Putative cytochrome P450		 SCLAV_5564
SSCG_06256		 Streptomyces clavuligerus ATCC 27064
74
 F8FJS9_9BACL
(F8FJS9)		 
[query] 9 - 412 (422)
[subject] 16 - 405 (416)
 1e-59 235   35% Cytochrome P450 KNP414_04885 Paenibacillus mucilaginosus KNP414
75
 B4VGK8_9ACTO
(B4VGK8)		 
[query] 22 - 419 (422)
[subject] 19 - 400 (402)
 1e-59 235   40% Cytochrome P450 SSAG_06886 Streptomyces sp. Mg1
76
 Q70AS4_STRPE
(Q70AS4)		 
[query] 49 - 422 (422)
[subject] 43 - 410 (413)
 1e-59 235   40% Putative cytochrome P450 cyp0749 Streptomyces peucetius 1.14.14.1
77
 B5HBZ5_STRPR
(B5HBZ5)		 
[query] 12 - 420 (422)
[subject] 7 - 400 (401)
 1e-59 235   37% Cytochrome P450 monooxygenase 107L14 SSDG_02678 Streptomyces pristinaespiralis ATCC 25486
78
 E8RXZ4_MICSL
(E8RXZ4)		 
[query] 1 - 412 (422)
[subject] 1 - 401 (412)
 2e-59 234   37% Cytochrome P450 ML5_4531 Micromonospora sp. (strain L5)
79
 B9J5W9_BACCQ
(B9J5W9)		 
[query] 13 - 405 (422)
[subject] 28 - 415 (430)
 4e-59 233   35% Cytochrome p450 BCQ_PI030 Bacillus cereus (strain Q1)
80
 C2ZZR4_BACCE
(C2ZZR4)		 
[query] 13 - 405 (422)
[subject] 28 - 415 (430)
 4e-59 233   35% Cytochrome p450 bcere0030_59720 Bacillus cereus AH1273
81
 C2ZGU2_BACCE
(C2ZGU2)		 
[query] 13 - 405 (422)
[subject] 28 - 415 (430)
 4e-59 233   35% Cytochrome p450 bcere0029_54800 Bacillus cereus AH1272
82
 C6WEG8_ACTMD
(C6WEG8)		 
[query] 8 - 406 (422)
[subject] 2 - 387 (403)
 6e-59 233   40% Cytochrome P450 Amir_3894 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
83
 D6U4A2_9CHLR
(D6U4A2)		 
[query] 12 - 405 (422)
[subject] 7 - 390 (406)
 6e-59 233   36% Cytochrome P450 Krac_2047 Ktedonobacter racemifer DSM 44963
84
 D6TKE0_9CHLR
(D6TKE0)		 
[query] 13 - 421 (422)
[subject] 8 - 407 (407)
 1e-58 232   35% Cytochrome P450 Krac_7531 Ktedonobacter racemifer DSM 44963
85
 D9VW13_9ACTO
(D9VW13)		 
[query] 17 - 384 (422)
[subject] 40 - 393 (399)
 1e-58 232   40% Cytochrome P450 107B1 SSNG_06468 Streptomyces sp. C
86
 A4X790_SALTO
(A4X790)		 
[query] 1 - 421 (422)
[subject] 4 - 398 (400)
 1e-58 232   37% Cytochrome P450 Strop_2290 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
87
 O87605_9ACTO
(O87605)		 Jump to Pikro_00170 
[query] 4 - 420 (422)
[subject] 9 - 404 (416)
 1e-58 231   37% Cytochrome P450 hydroxylase PiKC
Cytochrome P450 monooxygenase		 picK
pikC		 Streptomyces venezuelae
88
 Q82A10_STRAW
(Q82A10)		 
[query] 19 - 397 (422)
[subject] 7 - 366 (388)
 1e-58 231   38% Cytochrome P450 hydroxylase cyp23
SAV6249
SAV_6249		 Streptomyces avermitilis
89
 D9WIF6_9ACTO
(D9WIF6)		 
[query] 7 - 419 (422)
[subject] 16 - 419 (423)
 2e-58 231   39% Cytochrome P450 107B1 (P450CVIIB1) SSOG_05228 Streptomyces himastatinicus ATCC 53653
90
 F8K3Y0_STRCT
(F8K3Y0)		 
[query] 49 - 420 (422)
[subject] 44 - 403 (404)
 6e-58 229   41% Cytochrome P450 107B1 CYP107B
SCAT_3588		 Streptomyces cattleya 1.14.-.-
91
 D2AWQ3_STRRD
(D2AWQ3)		 
[query] 7 - 421 (422)
[subject] 11 - 411 (411)
 6e-58 229   38% Putative uncharacterized protein Sros_6100 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
92
 F2R6D7_STRVP
(F2R6D7)		 
[query] 1 - 422 (422)
[subject] 1 - 419 (425)
 7e-58 229   36% Putative cytochrome P450 hydroxylase SVEN_2902 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
93
 E3E222_BACA1
(E3E222)		 
[query] 16 - 422 (422)
[subject] 10 - 404 (413)
 8e-58 229   37% Cytochrome P450 of bacillaene metabolism BATR1942_06420 Bacillus atrophaeus (strain 1942)
94
 Q2BDN6_9BACI
(Q2BDN6)		 
[query] 14 - 421 (422)
[subject] 15 - 401 (402)
 1e-57 229   35% Cytochrome P450 B14911_27175 Bacillus sp. NRRL B-14911
95
 A6YRR5_STRVG
(A6YRR5)		 
[query] 12 - 420 (422)
[subject] 8 - 401 (402)
 1e-57 229   36% Cytochrome P450 monooxygenase 107L14 Streptomyces virginiae
96
 D9VLT4_9ACTO
(D9VLT4)		 
[query] 12 - 420 (422)
[subject] 8 - 401 (402)
 1e-57 228   36% Cytochrome P450 monooxygenase 107L14 SSNG_00342 Streptomyces sp. C
97
 B5HEW4_STRPR
(B5HEW4)		 
[query] 12 - 420 (422)
[subject] 6 - 400 (401)
 1e-57 228   37% Cytochrome P450 hydroxylase SSDG_03651 Streptomyces pristinaespiralis ATCC 25486
98
 C7PSG7_CHIPD
(C7PSG7)		 
[query] 12 - 396 (422)
[subject] 20 - 394 (420)
 1e-57 228   34% Cytochrome P450 Cpin_5300 Chitinophaga pinensis (strain ATCC 43595 / DSM 2588 / NCIB 11800 / UQM 2034)
99
 B6ZIR6_STRPT
(B6ZIR6)		 Jump to Pladi_00050 
[query] 14 - 405 (422)
[subject] 7 - 383 (399)
 1e-57 228   37% Cytochrome P450 pldB Streptomyces platensis
100
 E0TV47_BACPZ
(E0TV47)		 
[query] 14 - 422 (422)
[subject] 5 - 404 (405)
 2e-57 228   36% Cytochrome P450 of bacillaene metabolism pksS
BSUW23_08860		 Bacillus subtilis subsp. spizizenii (strain ATCC 23059 / NRRL B-14472 / W23)
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 O52569_AMYMD
(O52569)		 
[query] 1 - 422 (422)
[subject] 1 - 422 (422)
 0.0 855   100%
Product
Putative cytochrome P450 monooxygenase
Gene
 
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
2
 D8HZB4_AMYMU
(D8HZB4)		 
[query] 1 - 422 (422)
[subject] 3 - 424 (424)
 0.0 852   100%
Product
Cytochrome P450
Gene
AMED_0649
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
4
 D8HZA2_AMYMU
(D8HZA2)		 
[query] 1 - 422 (422)
[subject] 1 - 417 (421)
 1e-168 594   67%
Product
Cytochrome P450
Gene
AMED_0637
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
5
 O52561_AMYMD
(O52561)		 Jump to Rifam_00410 
[query] 1 - 422 (422)
[subject] 1 - 417 (421)
 1e-168 594   67%
Product
Putative cytochrome P450 monooxygenase
Gene
 
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
8
 Q595U3_9ACTO
(Q595U3)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 9e-87 325   43%
Product
Cytochrome P450 monooxygenase CYP107Z9
Gene
ema12
Organism
Streptomyces tubercidicus
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
9
 Q595V0_9ACTO
(Q595V0)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (432)
 1e-84 318   42%
Product
Cytochrome P450 monooxygenase CYP107Z6
Gene
ema5
Organism
Streptomyces sp. I-1525
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
10
 Q595U4_STRRY
(Q595U4)		 
[query] 13 - 421 (422)
[subject] 61 - 471 (475)
 6e-84 316   43%
Product
Cytochrome P450 monooxygenase CYP107Z1
Gene
ema11
Organism
Streptomyces rimosus subsp. paromomycinus
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
11
 Q595T8_9ACTO
(Q595T8)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 6e-84 316   42%
Product
Cytochrome P450 monooxygenase CYP107Z7
Gene
ema17
Organism
Streptomyces tubercidicus
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
12
 Q595T9_9ACTO
(Q595T9)		 
[query] 14 - 422 (422)
[subject] 22 - 430 (430)
 7e-84 315   43%
Product
Cytochrome P450 monooxygenase CYP107Z4
Gene
ema16
Organism
Streptomyces lydicus
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
13
 Q595V2_STRRY
(Q595V2)		 
[query] 13 - 398 (422)
[subject] 56 - 440 (470)
 2e-83 314   44%
Product
Cytochrome P450 monooxygenase CYP107Z2v2
Gene
ema3
Organism
Streptomyces rimosus subsp. paromomycinus
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
14
 Q595U7_9ACTO
(Q595U7)		 
[query] 13 - 398 (422)
[subject] 61 - 445 (475)
 5e-83 313   44%
Product
Cytochrome P450 monooxygenase CYP107Z2v1
Gene
ema8
Organism
Streptomyces albofaciens
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
15
 Q595U9_9ACTO
(Q595U9)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 5e-83 313   42%
Product
Cytochrome P450 monooxygenase CYP107Z5v2
Gene
Ema6
Organism
Streptomyces saraceticus
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
16
 Q595U2_STRPT
(Q595U2)		 
[query] 13 - 421 (422)
[subject] 21 - 429 (430)
 5e-83 313   41%
Product
Cytochrome P450 monooxygenase CYP107Z8
Gene
ema13
Organism
Streptomyces platensis
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
17
 Q595U0_9ACTO
(Q595U0)		 
[query] 13 - 421 (422)
[subject] 21 - 429 (430)
 1e-82 311   42%
Product
Cytochrome P450 monooxygenase CYP107Z5v1
Gene
em15
Organism
Streptomyces lydicus
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
18
 Q595V1_9ACTO
(Q595V1)		 
[query] 13 - 421 (422)
[subject] 21 - 429 (430)
 2e-82 311   42%
Product
Cytochrome P450 monooxygenase CYP107Z5v3
Gene
ema4
Organism
Streptomyces lydicus
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
19
 Q595U5_STRKA
(Q595U5)		 
[query] 13 - 421 (422)
[subject] 21 - 429 (430)
 2e-82 311   42%
Product
Cytochrome P450 monooxygenase CYP107Z5v3
Gene
ema10
Organism
Streptomyces kasugaensis
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
20
 Q60005_STRTH
(Q60005)		 
[query] 12 - 421 (422)
[subject] 4 - 411 (411)
 2e-80 304   42%
Product
Putative cytochrome P-450 protein
Gene
 
Organism
Streptomyces thermotolerans
1uniprot[Pubmed] 8074537 [Medline] 94354673
Cloning of the macrolide antibiotic biosynthesis gene acyA, which encodes 3-O-acyltransferase, from Streptomyces thermotolerans and its use for direct fermentative production of a hybrid macrolide antibiotic.(Appl. Environ. Microbiol.) [1994]
2uniprot[Pubmed] 7772821 [Medline] 95290751
Nucleotide sequence analysis of the carbomycin biosynthetic genes including the 3-O-acyltransferase gene from Streptomyces thermotolerans.(Biosci. Biotechnol. Biochem.) [1995]
[pubmed all]
21
 Q595U8_9ACTO
(Q595U8)		 
[query] 13 - 421 (422)
[subject] 21 - 428 (429)
 4e-80 303   41%
Product
Cytochrome P450 monooxygenase CYP107Z3
Gene
ema7
Organism
Streptomyces sp. IHS-0435
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
22
 Q595V6_9ACTO
(Q595V6)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 3e-79 300   40%
Product
Cytochrome P450 monooxygenase CYP107Z12
Gene
ema1
Organism
Streptomyces tubercidicus
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
23
 Q595U6_STRPT
(Q595U6)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 4e-79 300   40%
Product
Cytochrome P450 monooxygenase CYP107Z11
Gene
ema9
Organism
Streptomyces platensis
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
24
 Q595V3_9ACTO
(Q595V3)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 2e-77 294   40%
Product
Cytochrome P450 monooxygenase CYP107Z10
Gene
ema2
Organism
Streptomyces tubercidicus
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
25
 Q595U1_STRPT
(Q595U1)		 
[query] 13 - 422 (422)
[subject] 21 - 430 (430)
 2e-77 294   40%
Product
Cytochrome P450 monooxygenase CYP107Z10
Gene
ema14
Organism
Streptomyces platensis
1uniprot[Pubmed] 16269732
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005]
2uniprot[Pubmed] 16269733
Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005]
[pubmed all]
27
 D7AYD4_NOCDD
(D7AYD4)		 
[query] 1 - 421 (422)
[subject] 1 - 421 (421)
 5e-72 276   39%
Product
Cytochrome P450
Gene
Ndas_0674
Organism
Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]
28
 CPXJ_SACEN
(Q00441)		 
[query] 13 - 421 (422)
[subject] 6 - 402 (404)
 9e-71 272   40%
Product
6-deoxyerythronolide B hydroxylase
CYPCVIIA1
Cytochrome P450 107A1
Cytochrome P450eryF
Erythomycin A biosynthesis hydrolase
Gene
eryF
CYP107A1
SACE_0730
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 1840640 [Medline] 92079886
Cloning and sequence analysis of genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea: sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases.(Mol. Gen. Genet.) [1991]
2uniprot[Pubmed] 2011746 [Medline] 91188269
An erythromycin derivative produced by targeted gene disruption in Saccharopolyspora erythraea.(Science) [1991]
3uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
4uniprot[Pubmed] 7749919 [Medline] 95269057
Structure of cytochrome P450eryF involved in erythromycin biosynthesis.(Nat. Struct. Biol.) [1995]
5uniprot[Pubmed] 10716705 [Medline] 20202586
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity.(Proc. Natl. Acad. Sci. U.S.A.) [2000]
6uniprot[Pubmed] 11469860 [Medline] 21363699
Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF.(J. Mol. Biol.) [2001]
[pubmed all]
29
 A4FLS3_SACEN
(A4FLS3)		 
[query] 15 - 420 (422)
[subject] 12 - 402 (405)
 2e-69 267   41%
Product
Cytochrome P450-like enzyme
Gene
cypA
SACE_5814
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
30
 CPXK_SACEN
(P33271)		 
[query] 15 - 420 (422)
[subject] 12 - 402 (405)
 2e-69 267   41%
Product
Cytochrome P450 107B1
Cytochrome P450CVIIB1
Gene
CYP107B1
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 1732208 [Medline] 92121109
Characterization of Saccharopolyspora erythraea cytochrome P-450 genes and enzymes, including 6-deoxyerythronolide B hydroxylase.(J. Bacteriol.) [1992]
32
 D8HTB4_AMYMU
(D8HTB4)		 
[query] 20 - 421 (422)
[subject] 9 - 403 (403)
 2e-67 261   42%
Product
Cytochrome P450
Gene
AMED_2213
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
39
 D5SJQ5_STRCL
(D5SJQ5)		 
[query] 5 - 420 (422)
[subject] 54 - 465 (466)
 2e-65 254   37%
Product
Cytochrome P450 monooxygenase
Gene
SCLAV_p0661
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot
The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
40
 D1GLU0_9ACTO
(D1GLU0)		 Jump to Strply_00120 
[query] 18 - 422 (422)
[subject] 15 - 410 (413)
 5e-65 253   40%
Product
Cytochrome P450
Gene
slgO2
Organism
Streptomyces lydicus
1uniprot
Deciphering biosynthesis of the RNA polymerase inhibitor streptolydigin and generation of glycosylated derivatives.(Chem. Biol.) [2009]
41
 F3N9Q4_9ACTO
(F3N9Q4)		 
[query] 18 - 402 (422)
[subject] 8 - 373 (399)
 9e-65 252   42%
Product
Putative cytochrome P450
Gene
SGM_0088
Organism
Streptomyces griseoaurantiacus M045
1uniprot[Pubmed] 21551298
Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011]
42
 E4NIK6_KITSK
(E4NIK6)		 
[query] 2 - 403 (422)
[subject] 19 - 407 (428)
 2e-64 251   39%
Product
Putative cytochrome P450
Gene
KSE_70460
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
43
 D8HWS8_AMYMU
(D8HWS8)		 
[query] 12 - 410 (422)
[subject] 5 - 385 (391)
 3e-64 250   41%
Product
Cytochrome P450
Gene
AMED_4704
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
46
 Q83X67_STRRO
(Q83X67)		 
[query] 49 - 413 (422)
[subject] 42 - 394 (404)
 1e-62 245   40%
Product
P450 hydroxylase LkmK
Gene
lkmK
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
49
 Q737F3_BACC1
(Q737F3)		 
[query] 13 - 405 (422)
[subject] 8 - 395 (410)
 2e-62 244   37%
Product
Cytochrome p450
Gene
cypA
BCE_2696
Organism
Bacillus cereus (strain ATCC 10987)
1uniprot[Pubmed] 14960714
The genome sequence of Bacillus cereus ATCC 10987 reveals metabolic adaptations and a large plasmid related to Bacillus anthracis pXO1.(Nucleic Acids Res.) [2004]
52
 D7C4A9_STRBB
(D7C4A9)		 
[query] 17 - 405 (422)
[subject] 13 - 392 (418)
 6e-62 243   39%
Product
Cytochrome P450 hydroxylase
Gene
cyp14
SBI_00810
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
55
 Q5Y9H2_9ACTO
(Q5Y9H2)		 
[query] 13 - 394 (422)
[subject] 9 - 378 (406)
 3e-61 241   41%
Product
Cytochrome P450 oxidoreductase
Gene
eryF
Organism
Aeromicrobium erythreum
1uniprot[Pubmed] 15257441
The erythromycin biosynthetic gene cluster of Aeromicrobium erythreum.(J. Ind. Microbiol. Biotechnol.) [2004]
56
 A4F8W1_SACEN
(A4F8W1)		 
[query] 10 - 422 (422)
[subject] 2 - 391 (391)
 3e-61 240   38%
Product
Putative cytochrome P450
Gene
cyp23
SACE_1158
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
59
 D8HNZ6_AMYMU
(D8HNZ6)		 
[query] 8 - 393 (422)
[subject] 2 - 376 (402)
 4e-61 240   39%
Product
Cytochrome P450
Gene
AMED_3960
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
60
 Q83X78_STRRO
(Q83X78)		 
[query] 4 - 422 (422)
[subject] 7 - 405 (406)
 5e-61 239   37%
Product
P450 hydroxylase LkmF
Gene
lkmF
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
64
 F2QB25_STRPT
(F2QB25)		 
[query] 15 - 405 (422)
[subject] 10 - 386 (402)
 2e-60 238   39%
Product
Cytochrome P450 monooxygenase
Gene
p450
Organism
Streptomyces platensis
1uniprot
A new cytochrome P450 belonging to the 107L subfamily is responsible for the efficient hydroxylation of the drug terfenadine by Streptomyces platensis.(Arch. Biochem. Biophys.) [2011]
72
 A4F9M3_SACEN
(A4F9M3)		 
[query] 22 - 405 (422)
[subject] 18 - 379 (398)
 1e-59 235   39%
Product
Cytochrome P450-like enzyme
Gene
cypA
SACE_1426
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
73
 B5H3V7_STRCL
(B5H3V7)		 
[query] 16 - 421 (422)
[subject] 19 - 413 (418)
 1e-59 235   38%
Product
Cytochrome P450 monooxygenase 107L14
Putative cytochrome P450
Gene
SCLAV_5564
SSCG_06256
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
76
 Q70AS4_STRPE
(Q70AS4)		 
[query] 49 - 422 (422)
[subject] 43 - 410 (413)
 1e-59 235   40%
Product
Putative cytochrome P450
Gene
cyp0749
Organism
Streptomyces peucetius
1uniprot[Pubmed] 15111132
Genome analyses of Streptomyces peucetius ATCC 27952 for the identification and comparison of cytochrome P450 complement with other Streptomyces.(Arch. Biochem. Biophys.) [2004]
79
 B9J5W9_BACCQ
(B9J5W9)		 
[query] 13 - 405 (422)
[subject] 28 - 415 (430)
 4e-59 233   35%
Product
Cytochrome p450
Gene
BCQ_PI030
Organism
Bacillus cereus (strain Q1)
1uniprot[Pubmed] 19060151
Complete genome sequence of the extremophilic Bacillus cereus strain Q1 with industrial applications.(J. Bacteriol.) [2009]
82
 C6WEG8_ACTMD
(C6WEG8)		 
[query] 8 - 406 (422)
[subject] 2 - 387 (403)
 6e-59 233   40%
Product
Cytochrome P450
Gene
Amir_3894
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
87
 O87605_9ACTO
(O87605)		 Jump to Pikro_00170 
[query] 4 - 420 (422)
[subject] 9 - 404 (416)
 1e-58 231   37%
Product
Cytochrome P450 hydroxylase PiKC
Cytochrome P450 monooxygenase
Gene
picK
pikC
Organism
Streptomyces venezuelae
1uniprot[Pubmed] 9831532 [Medline] 99051447
Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae.(Chem. Biol.) [1998]
2uniprot[Pubmed] 16825192
The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae.(J. Biol. Chem.) [2006]
3uniprot[Pubmed] 19124459
Analysis of transient and catalytic desosamine-binding pockets in cytochrome P-450 PikC from Streptomyces venezuelae.(J. Biol. Chem.) [2009]
4uniprot[Pubmed] 19833867
Selective oxidation of carbolide C-H bonds by an engineered macrolide P450 mono-oxygenase.(Proc. Natl. Acad. Sci. U.S.A.) [2009]
5uniprot[Pubmed] 9770448 [Medline] 98445333
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.(Proc. Natl. Acad. Sci. U.S.A.) [1998]
6uniprot[Pubmed] 9778370 [Medline] 98453342
Characterization of the macrolide P-450 hydroxylase from Streptomyces venezuelae which converts narbomycin to picromycin.(Biochemistry) [1998]
[pubmed all]
88
 Q82A10_STRAW
(Q82A10)		 
[query] 19 - 397 (422)
[subject] 7 - 366 (388)
 1e-58 231   38%
Product
Cytochrome P450 hydroxylase
Gene
cyp23
SAV6249
SAV_6249
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
91
 D2AWQ3_STRRD
(D2AWQ3)		 
[query] 7 - 421 (422)
[subject] 11 - 411 (411)
 6e-58 229   38%
Product
Putative uncharacterized protein
Gene
Sros_6100
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
92
 F2R6D7_STRVP
(F2R6D7)		 
[query] 1 - 422 (422)
[subject] 1 - 419 (425)
 7e-58 229   36%
Product
Putative cytochrome P450 hydroxylase
Gene
SVEN_2902
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
99
 B6ZIR6_STRPT
(B6ZIR6)		 Jump to Pladi_00050 
[query] 14 - 405 (422)
[subject] 7 - 383 (399)
 1e-57 228   37%
Product
Cytochrome P450
Gene
pldB
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]