BLAST table : Spino_00210

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 Q9ALM2_9PSEU
(Q9ALM2)		 
[query] 1 - 5588 (5588)
[subject] 1 - 5588 (5588)
 0.0 11010   100% Polyketide synthase extender modules 8-10 spnE Saccharopolyspora spinosa
2
 E0L044_STRVO
(E0L044)		 
[query] 2 - 5286 (5588)
[subject] 4 - 5342 (7224)
(2 hsp)		 0.0 5035   54% Beta-ketoacyl synthase StrviDRAFT_8272 Streptomyces violaceusniger Tu 4113
3
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 32 - 5292 (5588)
[subject] 5573 - 10835 (10917)
(7 hsp)		 0.0 4672   52% AmphC amphC Streptomyces nodosus
4
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 34 - 5298 (5588)
[subject] 1578 - 6747 (6831)
(6 hsp)		 0.0 4670   53% ScnS1 scnS1 Streptomyces chattanoogensis
5
 Q82QT4_STRAW
(Q82QT4)		 
[query] 34 - 5286 (5588)
[subject] 2552 - 7657 (7746)
(10 hsp)		 0.0 4663   53% Modular polyketide synthase pteA1
SAV419
SAV_419		 Streptomyces avermitilis
6
 D7BRD4_STRBB
(D7BRD4)		 
[query] 41 - 5290 (5588)
[subject] 4605 - 9869 (9950)
(10 hsp)		 0.0 4662   53% Short-chain dehydrogenase/reductase SDR SBI_01976 Streptomyces bingchenggensis (strain BCW-1)
7
 A4X8L0_SALTO
(A4X8L0)		 
[query] 33 - 5290 (5588)
[subject] 1910 - 7129 (7210)
(4 hsp)		 0.0 4626   52% Beta-ketoacyl synthase Strop_2768 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
8
 Q52V52_9ACTO
(Q52V52)		 
[query] 1 - 5290 (5588)
[subject] 1 - 5349 (5432)
(2 hsp)		 0.0 4595   52% Polyketide synthase type I Streptomyces aizunensis
9
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 34 - 5298 (5588)
[subject] 1562 - 6713 (6797)
(7 hsp)		 0.0 4581   53% PimS1 protein
Polyketide synthase		 pimS1 Streptomyces natalensis
10
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 2 - 5297 (5588)
[subject] 3 - 5242 (10625)
(7 hsp)		 0.0 4576   53% FscC fscC Streptomyces sp. FR-008
11
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 1 - 5580 (5588)
[subject] 6 - 5400 (5400)
 0.0 4527   50% Short-chain dehydrogenase/reductase SDR Amir_2684 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
12
 D9T6W4_MICAI
(D9T6W4)		 
[query] 24 - 5297 (5588)
[subject] 1574 - 6827 (9936)
(14 hsp)		 0.0 4501   51% Beta-ketoacyl synthase Micau_2464 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442)
13
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 1 - 5298 (5588)
[subject] 1 - 5029 (5099)
 0.0 4489   51% Polyketide synthase type I Amycolatopsis orientalis
Nocardia orientalis
14
 E8S0C5_MICSL
(E8S0C5)		 
[query] 24 - 5290 (5588)
[subject] 1574 - 6819 (9937)
(14 hsp)		 0.0 4488   51% Beta-ketoacyl synthase ML5_5898 Micromonospora sp. (strain L5)
15
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 34 - 5292 (5588)
[subject] 5623 - 11014 (11096)
(5 hsp)		 0.0 4487   51% NysC nysC Streptomyces noursei
16
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 32 - 5298 (5588)
[subject] 1880 - 7039 (7110)
(4 hsp)		 0.0 4487   52% Short-chain dehydrogenase/reductase SDR Amir_2695 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
17
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 34 - 5290 (5588)
[subject] 1026 - 6300 (6383)
(6 hsp)		 0.0 4420   49% Polyketide synthase type I mlaA1 Streptomyces sp. MP39-85
18
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 34 - 5290 (5588)
[subject] 5584 - 10788 (10876)
(6 hsp)		 0.0 4410   52% CppC cppC Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
19
 B4VDY6_9ACTO
(B4VDY6)		 
[query] 29 - 4885 (5588)
[subject] 14 - 4843 (4894)
(4 hsp)		 0.0 4400   52% Polyketide synthase type I SSAG_05828 Streptomyces sp. Mg1
20
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 4 - 5294 (5588)
[subject] 5 - 5263 (5339)
 0.0 4390   50% Polyketide synthase natB Streptomyces sp. CS
21
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 34 - 5290 (5588)
[subject] 1022 - 6167 (6241)
(8 hsp)		 0.0 4361   50% Polyketide synthase KijS1 Actinomadura kijaniata
22
 B5L6K9_MICCH
(B5L6K9)		 
[query] 32 - 5283 (5588)
[subject] 1737 - 6926 (7007)
(4 hsp)		 0.0 4305   50% Putative type I polyketide synthase Micromonospora chalcea
23
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 2 - 5296 (5588)
[subject] 3 - 5111 (5176)
(2 hsp)		 0.0 4295   50% ObsB Saccharopolyspora spinosa
24
 D9VEY7_9ACTO
(D9VEY7)		 
[query] 34 - 5298 (5588)
[subject] 126 - 5219 (5260)
(3 hsp)		 0.0 4264   49% Modular polyketide synthase SSMG_05939 Streptomyces sp. AA4
25
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 1 - 5296 (5588)
[subject] 1 - 5247 (5321)
 0.0 4211   50% Polyketide synthase natC Streptomyces sp. CS
26
 E8WEN5_STRFA
(E8WEN5)		 
[query] 1 - 5302 (5588)
[subject] 1 - 5087 (5156)
(3 hsp)		 0.0 4160   49% Beta-ketoacyl synthase Sfla_0979 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
27
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 33 - 5316 (5588)
[subject] 991 - 5995 (6078)
(8 hsp)		 0.0 4140   50% ObsA Saccharopolyspora spinosa
28
 B5L6K8_MICCH
(B5L6K8)		 
[query] 35 - 5338 (5588)
[subject] 1023 - 6259 (6305)
(6 hsp)		 0.0 4130   47% Putative type I polyketide synthase Micromonospora chalcea
29
 A8M6C7_SALAI
(A8M6C7)		 
[query] 2 - 5290 (5588)
[subject] 3 - 5181 (5255)
(2 hsp)		 0.0 4101   49% Beta-ketoacyl synthase Sare_1247 Salinispora arenicola (strain CNS-205)
30
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 3 - 5290 (5588)
[subject] 4 - 5438 (5532)
(3 hsp)		 0.0 4046   48% Type I polyketide synthase AVES 3 aveA3
SAV942
SAV_942		 Streptomyces avermitilis
31
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 2 - 5290 (5588)
[subject] 3 - 5005 (5060)
(3 hsp)		 0.0 4031   48% Rifamycin polyketide synthase rifB
AMED_0618		 Amycolatopsis mediterranei (strain U-32)
32
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 2 - 5290 (5588)
[subject] 3 - 5005 (5060)
(3 hsp)		 0.0 4030   48% RifB rifB Amycolatopsis mediterranei
Nocardia mediterranei
33
 O52789_AMYMD
(O52789)		 
[query] 2 - 5290 (5588)
[subject] 12 - 5014 (5069)
(3 hsp)		 0.0 4026   48% Rifamycin polyketide synthase, type 1 Amycolatopsis mediterranei
Nocardia mediterranei
34
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 34 - 5463 (5588)
[subject] 8493 - 14029 (14130)
(13 hsp)		 0.0 3994   44% Type I modular polyketide synthase mlsB
MUP032c		 Mycobacterium ulcerans (strain Agy99)
35
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 34 - 5463 (5588)
[subject] 6697 - 12251 (12352)
(12 hsp)		 0.0 3990   44% Type I modular polyketide synthase, MlsB mlsB
MULP_051		 Mycobacterium liflandii 128FXT
36
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 34 - 4574 (5588)
[subject] 1027 - 5575 (5582)
(7 hsp)		 0.0 3953   49% Polyketide synthase type I becA Streptomyces sp. DSM 21069
37
 Q0PCZ9_STRHA
(Q0PCZ9)		 Jump to Halsto_00060 
[query] 1 - 4441 (5588)
[subject] 1 - 4503 (5232)
(7 hsp)		 0.0 3949   52% Type I polyketide synthase hlsF Streptomyces halstedii
38
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 32 - 5301 (5588)
[subject] 5252 - 10151 (10223)
(8 hsp)		 0.0 3919   47% Polyketide synthase rapB Streptomyces hygroscopicus
39
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 34 - 4917 (5588)
[subject] 3802 - 8569 (10827)
(15 hsp)		 0.0 3914   50% Type I modular polyketide synthase ttmJ Streptomyces spiroverticillatus
40
 F8JVX1_STRCT
(F8JVX1)		 
[query] 34 - 4439 (5588)
[subject] 1043 - 5399 (6125)
(11 hsp)		 0.0 3788   50% Putative 6-methylsalicylic acid synthase SCAT_0136 Streptomyces cattleya 2.3.1.165

2.3.1.94
41
 F8JUL0_STRCT
(F8JUL0)		 
[query] 34 - 4574 (5588)
[subject] 1030 - 5432 (5950)
(8 hsp)		 0.0 3779   51% Putative polyketide synthase SCAT_3270 Streptomyces cattleya
42
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 1 - 4445 (5588)
[subject] 1 - 4479 (5214)
(5 hsp)		 0.0 3758   51% Polyketide synthase idmN Streptomyces antibioticus
43
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 34 - 4920 (5588)
[subject] 4141 - 8783 (9528)
(14 hsp)		 0.0 3754   48% Type I modular polyketide synthase ttnA Streptomyces griseochromogenes
44
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 34 - 4920 (5588)
[subject] 4257 - 8903 (9648)
(14 hsp)		 0.0 3749   48% Tautomycetin biosynthetic PKS Streptomyces sp. CK4412
45
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 3 - 4464 (5588)
[subject] 7 - 4575 (7026)
(6 hsp)		 0.0 3723   50% Polyketide synthase pldAII Streptomyces platensis
46
 Q0RIF5_FRAAA
(Q0RIF5)		 
[query] 34 - 5287 (5588)
[subject] 1012 - 6354 (6432)
(8 hsp)		 0.0 3714   46% Putative type I polyketide synthase FRAAL4072 Frankia alni (strain ACN14a) 2.3.1.-
47
 D7F1M0_9ACTO
(D7F1M0)		 
[query] 1 - 4452 (5588)
[subject] 3 - 4407 (5136)
(5 hsp)		 0.0 3684   48% Polyketide synthase tsnAII Streptomyces longisporoflavus
48
 D9VBL5_9ACTO
(D9VBL5)		 
[query] 34 - 4215 (5588)
[subject] 982 - 4982 (5113)
(9 hsp)		 0.0 3683   53% Modular polyketide synthase SSMG_01148 Streptomyces sp. AA4
49
 Q52V50_9ACTO
(Q52V50)		 
[query] 1402 - 5290 (5588)
[subject] 3551 - 7427 (7510)
(7 hsp)		 0.0 3636   54% Polyketide synthase type I Streptomyces aizunensis
50
 D7P611_CHOCO
(D7P611)		 
[query] 479 - 4917 (5588)
[subject] 989 - 5460 (6255)
(9 hsp)		 0.0 3594   48% TugA tugA Chondromyces crocatus
51
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1 - 4564 (5588)
[subject] 1 - 4389 (8301)
(8 hsp)		 0.0 3552   51% Type I polyketide synthase sfaH Streptomyces flaveolus
52
 A8LUX2_SALAI
(A8LUX2)		 
[query] 34 - 4440 (5588)
[subject] 991 - 5199 (7279)
(15 hsp)		 0.0 3544   49% Beta-ketoacyl synthase Sare_3156 Salinispora arenicola (strain CNS-205)
53
 Q52V53_9ACTO
(Q52V53)		 
[query] 1309 - 5291 (5588)
[subject] 1119 - 5128 (5207)
(7 hsp)		 0.0 3533   53% Polyketide synthase type I Streptomyces aizunensis
54
 Q52V49_9ACTO
(Q52V49)		 
[query] 1782 - 5578 (5588)
[subject] 33 - 3869 (3872)
(4 hsp)		 0.0 3460   53% Polyketide synthase type I Streptomyces aizunensis
55
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 1 - 4923 (5588)
[subject] 1 - 4503 (6260)
(9 hsp)		 0.0 3459   46% Polyketide synthase rapC Streptomyces hygroscopicus
56
 B4VB11_9ACTO
(B4VB11)		 
[query] 1463 - 5290 (5588)
[subject] 5 - 3842 (3928)
(4 hsp)		 0.0 3439   54% Polyketide synthase type I SSAG_04921 Streptomyces sp. Mg1
57
 E9KTB5_STRKN
(E9KTB5)		 
[query] 34 - 5301 (5588)
[subject] 1171 - 5991 (7591)
(9 hsp)		 0.0 3436   44% Polyketide synthase fkbB
Tcs_SK_031		 Streptomyces kanamyceticus
58
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 3 - 4704 (5588)
[subject] 4 - 4569 (5066)
(6 hsp)		 0.0 3428   47% Putative polyketide synthase rubB Streptomyces achromogenes subsp. rubradiris
59
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 1780 - 4444 (5588)
[subject] 36 - 2675 (4928)
(10 hsp)		 0.0 3389   69% Polyketide synthase extender modules 5-7 spnD Saccharopolyspora spinosa
60
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 1387 - 5581 (5588)
[subject] 3382 - 7488 (7488)
(5 hsp)		 0.0 3367   50% ObsC Saccharopolyspora spinosa
61
 Q93H87_STRAW
(Q93H87)		 
[query] 1186 - 5286 (5588)
[subject] 1938 - 5959 (6048)
(10 hsp)		 0.0 3361   50% Modular polyketide synthase pteA1 Streptomyces avermitilis
62
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 34 - 5300 (5588)
[subject] 1183 - 5987 (7576)
(9 hsp)		 0.0 3335   44% FK506 polyketide synthase fkbB Streptomyces sp. MA6548
63
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 34 - 4922 (5588)
[subject] 18 - 5038 (17019)
(15 hsp)		 0.0 3335   42% Type I modular polyketide synthase, MlsA1 mlsA1
MULP_065		 Mycobacterium liflandii 128FXT
64
 F1D8Z6_9ACTO
(F1D8Z6)		 
[query] 34 - 4750 (5588)
[subject] 2821 - 7236 (7655)
(6 hsp)		 0.0 3333   47% FkbB Streptomyces sp. MJM7001
65
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 34 - 4922 (5588)
[subject] 18 - 5040 (16990)
(15 hsp)		 0.0 3330   42% Type I modular polyketide synthase mlsA1
MUP040c		 Mycobacterium ulcerans (strain Agy99)
66
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 34 - 4750 (5588)
[subject] 2812 - 7227 (7646)
(6 hsp)		 0.0 3329   47% Polyketide synthase fkbB
Tcs_11604BP_028		 Streptomyces sp. KCTC 11604BP
67
 Q0PD02_STRHA
(Q0PD02)		 Jump to Halsto_00030 
[query] 1311 - 5290 (5588)
[subject] 1108 - 5134 (5220)
(5 hsp)		 0.0 3314   50% Type I polyketide synthase hlsC Streptomyces halstedii
68
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 1325 - 5290 (5588)
[subject] 1689 - 5630 (5718)
(6 hsp)		 0.0 3284   49% ChlA3 Streptomyces antibioticus
69
 D6B4Q9_9ACTO
(D6B4Q9)		 
[query] 1306 - 5293 (5588)
[subject] 112 - 4011 (5945)
(6 hsp)		 0.0 3264   51% Polyketide synthase SSHG_00090 Streptomyces albus J1074
70
 D6C477_9ACTO
(D6C477)		 Jump to Meili_00310 
[query] 1399 - 5290 (5588)
[subject] 1784 - 5734 (5822)
(6 hsp)		 0.0 3256   51% Modular polyketide synthase meiA3 Streptomyces nanchangensis
71
 D7C2B8_STRBB
(D7C2B8)		 
[query] 1374 - 4923 (5588)
[subject] 3227 - 6728 (7498)
(15 hsp)		 0.0 3244   53% Type I modular polyketide synthase pks3-2
SBI_00651		 Streptomyces bingchenggensis (strain BCW-1)
72
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 1434 - 5290 (5588)
[subject] 1871 - 5744 (5826)
(7 hsp)		 0.0 3234   51% Polyketide synthase modules 1-3 vinP1 Streptomyces halstedii
73
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 1782 - 5286 (5588)
[subject] 34 - 3530 (3612)
(4 hsp)		 0.0 3226   52% LipPks3 lipPks3 Streptomyces aureofaciens
74
 A4X8M0_SALTO
(A4X8M0)		 
[query] 1782 - 5579 (5588)
[subject] 34 - 3711 (3711)
(3 hsp)		 0.0 3192   51% Beta-ketoacyl synthase Strop_2778 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
75
 C6K7D8_9ACTO
(C6K7D8)		 
[query] 34 - 4744 (5588)
[subject] 3150 - 7394 (7938)
(10 hsp)		 0.0 3182   45% Polyketide synthase rapA Actinoplanes sp. N902-109
76
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 1780 - 5340 (5588)
[subject] 34 - 3546 (3596)
(2 hsp)		 0.0 3146   51% Polyketide synthase idmM Streptomyces antibioticus
77
 E0L075_STRVO
(E0L075)		 
[query] 1782 - 4924 (5588)
[subject] 34 - 3161 (5786)
(11 hsp)		 0.0 3105   55% Beta-ketoacyl synthase StrviDRAFT_8303 Streptomyces violaceusniger Tu 4113
78
 A8J704_9ACTO
(A8J704)		 
[query] 1397 - 5281 (5588)
[subject] 1718 - 5579 (5674)
(6 hsp)		 0.0 3100   49% Modular polyketide synthase nemA3 Streptomyces cyaneogriseus subsp. noncyanogenus
79
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 1 - 3543 (5588)
[subject] 1 - 3511 (3582)
(2 hsp)		 0.0 3098   52% LipPks2 lipPks2 Streptomyces aureofaciens
80
 D7F1M1_9ACTO
(D7F1M1)		 
[query] 1403 - 5297 (5588)
[subject] 1718 - 5554 (5630)
(7 hsp)		 0.0 3075   47% Polyketide synthase tsnAIII Streptomyces longisporoflavus
81
 D6EJM4_STRLI
(D6EJM4)		 
[query] 1691 - 5286 (5588)
[subject] 969 - 4516 (4599)
(6 hsp)		 0.0 3075   51% Type I polyketide synthase SSPG_01356 Streptomyces lividans TK24
82
 E0D206_9ACTO
(E0D206)		 Jump to FD891_00050 
[query] 1782 - 5581 (5588)
[subject] 34 - 3799 (3799)
(2 hsp)		 0.0 3073   49% Polyketide synthase gfsE Streptomyces graminofaciens
83
 Q8CJN6_STRCO
(Q8CJN6)		 
[query] 1691 - 5296 (5588)
[subject] 925 - 4488 (4557)
(6 hsp)		 0.0 3063   51% Putative type I polyketide synthase SCO6275 Streptomyces coelicolor
84
 Q82QT5_STRAW
(Q82QT5)		 
[query] 1780 - 5296 (5588)
[subject] 32 - 3486 (3564)
(2 hsp)		 0.0 3039   52% Modular polyketide synthase pteA2
SAV418
SAV_418		 Streptomyces avermitilis
85
 E8WEN9_STRFA
(E8WEN9)		 
[query] 5 - 3535 (5588)
[subject] 6 - 3420 (3511)
(3 hsp)		 0.0 3028   51% Mycocerosate synthase, 6-deoxyerythronolide-B synthase Sfla_0983 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD) 2.3.1.111

2.3.1.94
86
 Q93H86_STRAW
(Q93H86)		 
[query] 1789 - 5296 (5588)
[subject] 1 - 3446 (3524)
(3 hsp)		 0.0 3027   52% Modular polyketide synthase pteA2 Streptomyces avermitilis
87
 F8QPG1_9ACTO
(F8QPG1)		 
[query] 1 - 3545 (5588)
[subject] 1 - 3547 (3621)
(2 hsp)		 0.0 3024   52% Polyketide synthase natD Streptomyces sp. CS
88
 E0L045_STRVO
(E0L045)		 
[query] 2045 - 5291 (5588)
[subject] 1 - 3274 (3357)
(4 hsp)		 0.0 3011   53% Short-chain dehydrogenase/reductase SDR StrviDRAFT_8273 Streptomyces violaceusniger Tu 4113
89
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 2 - 3536 (5588)
[subject] 5 - 3292 (3373)
(4 hsp)		 0.0 3006   51% Polyketide synthase type I mlaF Streptomyces sp. MP39-85
90
 E0KFI9_STRVO
(E0KFI9)		 
[query] 1306 - 4441 (5588)
[subject] 2750 - 5914 (8238)
(19 hsp)		 0.0 3002   54% Beta-ketoacyl synthase StrviDRAFT_1372 Streptomyces violaceusniger Tu 4113
91
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 2 - 3535 (5588)
[subject] 5 - 3294 (3377)
(4 hsp)		 0.0 3000   51% Polyketide synthase type I becF Streptomyces sp. DSM 21069
92
 Q9EX53_STRCO
(Q9EX53)		 
[query] 1780 - 5298 (5588)
[subject] 32 - 3500 (3576)
(2 hsp)		 0.0 2989   50% Putative type I polyketide synthase SCO6274 Streptomyces coelicolor
93
 D9WQ64_9ACTO
(D9WQ64)		 
[query] 1306 - 4441 (5588)
[subject] 523 - 3637 (3874)
(7 hsp)		 0.0 2987   54% Modular polyketide synthase SSOG_05738 Streptomyces himastatinicus ATCC 53653
94
 A4FH84_SACEN
(A4FH84)		 
[query] 1782 - 5290 (5588)
[subject] 34 - 3404 (3481)
(3 hsp)		 0.0 2981   52% Type I modular polyketide synthase SACE_4140 Saccharopolyspora erythraea (strain NRRL 23338)
95
 Q5VKQ8_SACER
(Q5VKQ8)		 
[query] 1782 - 5290 (5588)
[subject] 34 - 3404 (3481)
(3 hsp)		 0.0 2981   52% Type I PKS pkeAII Saccharopolyspora erythraea
Streptomyces erythraeus
96
 D9WQ83_9ACTO
(D9WQ83)		 
[query] 1782 - 4740 (5588)
[subject] 43 - 2990 (3002)
(3 hsp)		 0.0 2981   56% Modular polyketide synthase SSOG_05757 Streptomyces himastatinicus ATCC 53653
97
 E0KFI7_STRVO
(E0KFI7)		 
[query] 1309 - 4441 (5588)
[subject] 2821 - 5989 (8538)
(12 hsp)		 0.0 2976   53% Beta-ketoacyl synthase StrviDRAFT_1370 Streptomyces violaceusniger Tu 4113
98
 Q1MX73_9ACTO
(Q1MX73)		 Jump to Tetrn_00160 
[query] 1403 - 5291 (5588)
[subject] 1735 - 5576 (5657)
(6 hsp)		 0.0 2967   45% Type I polyketide synthase tmnAIV Streptomyces sp. NRRL 11266
99
 D9WQ70_9ACTO
(D9WQ70)		 
[query] 1309 - 4441 (5588)
[subject] 1819 - 4982 (5483)
(12 hsp)		 0.0 2963   54% Modular polyketide synthase SSOG_05744 Streptomyces himastatinicus ATCC 53653
100
 D9WQL2_9ACTO
(D9WQL2)		 
[query] 1775 - 5284 (5588)
[subject] 31 - 3284 (3284)
(3 hsp)		 0.0 2953   51% Modular polyketide synthase SSOG_07859 Streptomyces himastatinicus ATCC 53653
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
 Q9ALM2_9PSEU
(Q9ALM2)		 
[query] 1 - 5588 (5588)
[subject] 1 - 5588 (5588)
 0.0 11010   100%
Product
Polyketide synthase extender modules 8-10
Gene
spnE
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
3
 Q93NW6_9ACTO
(Q93NW6)		 Jump to Amph_00170 
[query] 32 - 5292 (5588)
[subject] 5573 - 10835 (10917)
(7 hsp)		 0.0 4672   52%
Product
AmphC
Gene
amphC
Organism
Streptomyces nodosus
1uniprot[Pubmed] 11451671 [Medline] 21344785
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.(Chem. Biol.) [2001]
2uniprot[Pubmed] 16079135
Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups.(J. Biol. Chem.) [2005]
[pubmed all]
4
 F1CLC1_9ACTO
(F1CLC1)		 
[query] 34 - 5298 (5588)
[subject] 1578 - 6747 (6831)
(6 hsp)		 0.0 4670   53%
Product
ScnS1
Gene
scnS1
Organism
Streptomyces chattanoogensis
1uniprot[Pubmed] 21330439
The pleitropic regulator AdpAch is required for natamycin biosynthesis and morphological differentiation in Streptomyces chattanoogensis.(Microbiology) [2011]
5
 Q82QT4_STRAW
(Q82QT4)		 
[query] 34 - 5286 (5588)
[subject] 2552 - 7657 (7746)
(10 hsp)		 0.0 4663   53%
Product
Modular polyketide synthase
Gene
pteA1
SAV419
SAV_419
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
6
 D7BRD4_STRBB
(D7BRD4)		 
[query] 41 - 5290 (5588)
[subject] 4605 - 9869 (9950)
(10 hsp)		 0.0 4662   53%
Product
Short-chain dehydrogenase/reductase SDR
Gene
SBI_01976
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
8
 Q52V52_9ACTO
(Q52V52)		 
[query] 1 - 5290 (5588)
[subject] 1 - 5349 (5432)
(2 hsp)		 0.0 4595   52%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
9
 Q9X993_9ACTO
(Q9X993)		 Jump to Pimar_00170 
[query] 34 - 5298 (5588)
[subject] 1562 - 6713 (6797)
(7 hsp)		 0.0 4581   53%
Product
PimS1 protein
Polyketide synthase
Gene
pimS1
Organism
Streptomyces natalensis
1uniprot[Pubmed] 10187796 [Medline] 99214571
The biosynthetic gene cluster for the 26-membered ring polyene macrolide pimaricin. A new polyketide synthase organization encoded by two subclusters separated by functionalization genes.(J. Biol. Chem.) [1999]
2uniprot[Pubmed] 11094342 [Medline] 20547809
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.(Chem. Biol.) [2000]
[pubmed all]
10
 Q6W5Q0_9ACTO
(Q6W5Q0)		 Jump to FR008_00160 
[query] 2 - 5297 (5588)
[subject] 3 - 5242 (10625)
(7 hsp)		 0.0 4576   53%
Product
FscC
Gene
fscC
Organism
Streptomyces sp. FR-008
1uniprot[Pubmed] 14652074
Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex.(Chem. Biol.) [2003]
11
 C6WNV0_ACTMD
(C6WNV0)		 
[query] 1 - 5580 (5588)
[subject] 6 - 5400 (5400)
 0.0 4527   50%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2684
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
13
 A1YAN0_AMYOR
(A1YAN0)		 
[query] 1 - 5298 (5588)
[subject] 1 - 5029 (5099)
 0.0 4489   51%
Product
Polyketide synthase type I
Gene
 
Organism
Amycolatopsis orientalis
Nocardia orientalis
1uniprot[Pubmed] 17136886
Genomic analyses lead to novel secondary metabolites. Part 3. ECO-0501, a novel antibacterial of a new class.(J. Antibiot.) [2006]
15
 Q9L4W3_9ACTO
(Q9L4W3)		 Jump to Nysta_00150 
[query] 34 - 5292 (5588)
[subject] 5623 - 11014 (11096)
(5 hsp)		 0.0 4487   51%
Product
NysC
Gene
nysC
Organism
Streptomyces noursei
1uniprot[Pubmed] 10873841 [Medline] 20334850
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.(Chem. Biol.) [2000]
16
 C6WNW1_ACTMD
(C6WNW1)		 
[query] 32 - 5298 (5588)
[subject] 1880 - 7039 (7110)
(4 hsp)		 0.0 4487   52%
Product
Short-chain dehydrogenase/reductase SDR
Gene
Amir_2695
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
17
 C3VLY1_9ACTO
(C3VLY1)		 
[query] 34 - 5290 (5588)
[subject] 1026 - 6300 (6383)
(6 hsp)		 0.0 4420   49%
Product
Polyketide synthase type I
Gene
mlaA1
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
18
 D2CKM4_PSEAH
(D2CKM4)		 
[query] 34 - 5290 (5588)
[subject] 5584 - 10788 (10876)
(6 hsp)		 0.0 4410   52%
Product
CppC
Gene
cppC
Organism
Pseudonocardia autotrophica
Amycolata autotrophica
Nocardia autotrophica
1uniprot[Pubmed] 19697072
Identification of functionally clustered nystatin-like biosynthetic genes in a rare actinomycetes, Pseudonocardia autotrophica.(J. Ind. Microbiol. Biotechnol.) [2009]
20
 F8QPF9_9ACTO
(F8QPF9)		 
[query] 4 - 5294 (5588)
[subject] 5 - 5263 (5339)
 0.0 4390   50%
Product
Polyketide synthase
Gene
natB
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
21
 B3TMQ8_9ACTO
(B3TMQ8)		 
[query] 34 - 5290 (5588)
[subject] 1022 - 6167 (6241)
(8 hsp)		 0.0 4361   50%
Product
Polyketide synthase
Gene
KijS1
Organism
Actinomadura kijaniata
1uniprot[Pubmed] 17985890
Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars.(J. Am. Chem. Soc.) [2007]
22
 B5L6K9_MICCH
(B5L6K9)		 
[query] 32 - 5283 (5588)
[subject] 1737 - 6926 (7007)
(4 hsp)		 0.0 4305   50%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
23
 Q6JHN7_9PSEU
(Q6JHN7)		 
[query] 2 - 5296 (5588)
[subject] 3 - 5111 (5176)
(2 hsp)		 0.0 4295   50%
Product
ObsB
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
25
 F8QPG0_9ACTO
(F8QPG0)		 
[query] 1 - 5296 (5588)
[subject] 1 - 5247 (5321)
 0.0 4211   50%
Product
Polyketide synthase
Gene
natC
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
27
 Q6JHN8_9PSEU
(Q6JHN8)		 
[query] 33 - 5316 (5588)
[subject] 991 - 5995 (6078)
(8 hsp)		 0.0 4140   50%
Product
ObsA
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
28
 B5L6K8_MICCH
(B5L6K8)		 
[query] 35 - 5338 (5588)
[subject] 1023 - 6259 (6305)
(6 hsp)		 0.0 4130   47%
Product
Putative type I polyketide synthase
Gene
 
Organism
Micromonospora chalcea
1uniprot[Pubmed] 18586939
Cloning and characterization of the tetrocarcin A gene cluster from Micromonospora chalcea NRRL 11289 reveals a highly conserved strategy for tetronate biosynthesis in spirotetronate antibiotics.(J. Bacteriol.) [2008]
30
 Q9S0R4_STRAW
(Q9S0R4)		 Jump to Aver_00080 
[query] 3 - 5290 (5588)
[subject] 4 - 5438 (5532)
(3 hsp)		 0.0 4046   48%
Product
Type I polyketide synthase AVES 3
Gene
aveA3
SAV942
SAV_942
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 10449723 [Medline] 99380548
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis.(Proc. Natl. Acad. Sci. U.S.A.) [1999]
2uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
3uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
31
 D8HZ83_AMYMU
(D8HZ83)		 
[query] 2 - 5290 (5588)
[subject] 3 - 5005 (5060)
(3 hsp)		 0.0 4031   48%
Product
Rifamycin polyketide synthase
Gene
rifB
AMED_0618
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
32
 O52545_AMYMD
(O52545)		 Jump to Rifam_00220 
[query] 2 - 5290 (5588)
[subject] 3 - 5005 (5060)
(3 hsp)		 0.0 4030   48%
Product
RifB
Gene
rifB
Organism
Amycolatopsis mediterranei
Nocardia mediterranei
1uniprot[Pubmed] 9512878 [Medline] 98174059
Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699.(Chem. Biol.) [1998]
2uniprot[Pubmed] 9497318 [Medline] 98165773
3-amino-5-hydroxybenzoic acid synthase, the terminal enzyme in the formation of the precursor of mC7N units in rifamycin and related antibiotics.(J. Biol. Chem.) [1998]
3uniprot[Pubmed] 11278540 [Medline] 21201076
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.(J. Biol. Chem.) [2001]
[pubmed all]
34
 Q6MZ72_MYCUA
(Q6MZ72)		 Jump to MUP_00320 
[query] 34 - 5463 (5588)
[subject] 8493 - 14029 (14130)
(13 hsp)		 0.0 3994   44%
Product
Type I modular polyketide synthase
Gene
mlsB
MUP032c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
2uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
[pubmed all]
35
 B6CLY1_9MYCO
(B6CLY1)		 
[query] 34 - 5463 (5588)
[subject] 6697 - 12251 (12352)
(12 hsp)		 0.0 3990   44%
Product
Type I modular polyketide synthase, MlsB
Gene
mlsB
MULP_051
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
36
 C3VLV4_9ACTO
(C3VLV4)		 
[query] 34 - 4574 (5588)
[subject] 1027 - 5575 (5582)
(7 hsp)		 0.0 3953   49%
Product
Polyketide synthase type I
Gene
becA
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
38
 Q54296_STRHY
(Q54296)		 Jump to Rapam_00110 
[query] 32 - 5301 (5588)
[subject] 5252 - 10151 (10223)
(8 hsp)		 0.0 3919   47%
Product
Polyketide synthase
Gene
rapB
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
39
 C0SMW4_9ACTO
(C0SMW4)		 Jump to Tauto_00110 
[query] 34 - 4917 (5588)
[subject] 3802 - 8569 (10827)
(15 hsp)		 0.0 3914   50%
Product
Type I modular polyketide synthase
Gene
ttmJ
Organism
Streptomyces spiroverticillatus
1uniprot[Pubmed] 16707708
Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus.(J. Bacteriol.) [2006]
2uniprot[Pubmed] 18708355
Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.(J. Biol. Chem.) [2008]
[pubmed all]
42
 C5HV16_STRAT
(C5HV16)		 Jump to Indano_00180 
[query] 1 - 4445 (5588)
[subject] 1 - 4479 (5214)
(5 hsp)		 0.0 3758   51%
Product
Polyketide synthase
Gene
idmN
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
43
 C6ZCS1_9ACTO
(C6ZCS1)		 
[query] 34 - 4920 (5588)
[subject] 4141 - 8783 (9528)
(14 hsp)		 0.0 3754   48%
Product
Type I modular polyketide synthase
Gene
ttnA
Organism
Streptomyces griseochromogenes
1uniprot[Pubmed] 19191560
Characterization of the Tautomycetin Biosynthetic Gene Cluster from Streptomyces griseochromogenes Provides New Insight into Dialkylmaleic Anhydride Biosynthesis.(J. Nat. Prod.) [2009]
44
 A4KCE4_9ACTO
(A4KCE4)		 Jump to Tatmc_00080 
[query] 34 - 4920 (5588)
[subject] 4257 - 8903 (9648)
(14 hsp)		 0.0 3749   48%
Product
Tautomycetin biosynthetic PKS
Gene
 
Organism
Streptomyces sp. CK4412
1uniprot[Pubmed] 17379718
Isolation of the biosynthetic gene cluster for tautomycetin, a linear polyketide T cell-specific immunomodulator from Streptomyces sp. CK4412.(Microbiology) [2007]
45
 B6ZIR3_STRPT
(B6ZIR3)		 Jump to Pladi_00020 
[query] 3 - 4464 (5588)
[subject] 7 - 4575 (7026)
(6 hsp)		 0.0 3723   50%
Product
Polyketide synthase
Gene
pldAII
Organism
Streptomyces platensis
1uniprot[Pubmed] 18997414
Organization of the biosynthetic gene cluster for the polyketide antitumor macrolide, pladienolide, in Streptomyces platensis Mer-11107.(Biosci. Biotechnol. Biochem.) [2008]
46
 Q0RIF5_FRAAA
(Q0RIF5)		 
[query] 34 - 5287 (5588)
[subject] 1012 - 6354 (6432)
(8 hsp)		 0.0 3714   46%
Product
Putative type I polyketide synthase
Gene
FRAAL4072
Organism
Frankia alni (strain ACN14a)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
49
 Q52V50_9ACTO
(Q52V50)		 
[query] 1402 - 5290 (5588)
[subject] 3551 - 7427 (7510)
(7 hsp)		 0.0 3636   54%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
50
 D7P611_CHOCO
(D7P611)		 
[query] 479 - 4917 (5588)
[subject] 989 - 5460 (6255)
(9 hsp)		 0.0 3594   48%
Product
TugA
Gene
tugA
Organism
Chondromyces crocatus
1uniprot[Pubmed] 20416506
Biosynthesis of thuggacins in myxobacteria: comparative cluster analysis reveals basis for natural product structural diversity.(Chem. Biol.) [2010]
51
 D3U9Y8_9ACTO
(D3U9Y8)		 
[query] 1 - 4564 (5588)
[subject] 1 - 4389 (8301)
(8 hsp)		 0.0 3552   51%
Product
Type I polyketide synthase
Gene
sfaH
Organism
Streptomyces flaveolus
1uniprot
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor.(Mol. Biosyst.) [2010]
53
 Q52V53_9ACTO
(Q52V53)		 
[query] 1309 - 5291 (5588)
[subject] 1119 - 5128 (5207)
(7 hsp)		 0.0 3533   53%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
54
 Q52V49_9ACTO
(Q52V49)		 
[query] 1782 - 5578 (5588)
[subject] 33 - 3869 (3872)
(4 hsp)		 0.0 3460   53%
Product
Polyketide synthase type I
Gene
 
Organism
Streptomyces aizunensis
1uniprot[Pubmed] 15844935
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.(J. Nat. Prod.) [2005]
55
 Q54299_STRHY
(Q54299)		 Jump to Rapam_00140 
[query] 1 - 4923 (5588)
[subject] 1 - 4503 (6260)
(9 hsp)		 0.0 3459   46%
Product
Polyketide synthase
Gene
rapC
Organism
Streptomyces hygroscopicus
1uniprot[Pubmed] 7644502 [Medline] 95372374
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.(Proc. Natl. Acad. Sci. U.S.A.) [1995]
2uniprot[Pubmed] 8635730 [Medline] 96186895
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.(Gene) [1996]
3uniprot[Pubmed] 8635756 [Medline] 96186896
Organization of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of the enzymatic domains in the modular polyketide synthase.(Gene) [1996]
[pubmed all]
57
 E9KTB5_STRKN
(E9KTB5)		 
[query] 34 - 5301 (5588)
[subject] 1171 - 5991 (7591)
(9 hsp)		 0.0 3436   44%
Product
Polyketide synthase
Gene
fkbB
Tcs_SK_031
Organism
Streptomyces kanamyceticus
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
58
 Q2PC52_STRAH
(Q2PC52)		 Jump to Rubra_00380 
[query] 3 - 4704 (5588)
[subject] 4 - 4569 (5066)
(6 hsp)		 0.0 3428   47%
Product
Putative polyketide synthase
Gene
rubB
Organism
Streptomyces achromogenes subsp. rubradiris
1uniprot[Pubmed] 9387157 [Medline] 98048398
Identification of a gene cluster of biosynthetic genes of rubradirin substructures in S. achromogenes var. rubradiris NRRL3061.(Mol. Cells) [1997]
2uniprot[Pubmed] 12889805 [Medline] 22771458
Functional identification of rub52 gene involved in the biosynthesis of rubradirin.(Biotechnol. Lett.) [2003]
[pubmed all]
59
 Q9ALM3_9PSEU
(Q9ALM3)		 Jump to Spino_00200 
[query] 1780 - 4444 (5588)
[subject] 36 - 2675 (4928)
(10 hsp)		 0.0 3389   69%
Product
Polyketide synthase extender modules 5-7
Gene
spnD
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 11358695 [Medline] 21257765
Cloning and analysis of the spinosad biosynthetic gene cluster of Saccharopolyspora spinosa.(Chem. Biol.) [2001]
60
 Q6JHN6_9PSEU
(Q6JHN6)		 
[query] 1387 - 5581 (5588)
[subject] 3382 - 7488 (7488)
(5 hsp)		 0.0 3367   50%
Product
ObsC
Gene
 
Organism
Saccharopolyspora spinosa
1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]
61
 Q93H87_STRAW
(Q93H87)		 
[query] 1186 - 5286 (5588)
[subject] 1938 - 5959 (6048)
(10 hsp)		 0.0 3361   50%
Product
Modular polyketide synthase
Gene
pteA1
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
62
 Q9ZGA4_9ACTO
(Q9ZGA4)		 
[query] 34 - 5300 (5588)
[subject] 1183 - 5987 (7576)
(9 hsp)		 0.0 3335   44%
Product
FK506 polyketide synthase
Gene
fkbB
Organism
Streptomyces sp. MA6548
1uniprot[Pubmed] 9780228 [Medline] 98451508
The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506.(Eur. J. Biochem.) [1998]
63
 B6CLY8_9MYCO
(B6CLY8)		 
[query] 34 - 4922 (5588)
[subject] 18 - 5038 (17019)
(15 hsp)		 0.0 3335   42%
Product
Type I modular polyketide synthase, MlsA1
Gene
mlsA1
MULP_065
Organism
Mycobacterium liflandii 128FXT
1uniprot[Pubmed] 18840298
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.(BMC Genomics) [2008]
65
 Q6MZA4_MYCUA
(Q6MZA4)		 Jump to MUP_00400 
[query] 34 - 4922 (5588)
[subject] 18 - 5040 (16990)
(15 hsp)		 0.0 3330   42%
Product
Type I modular polyketide synthase
Gene
mlsA1
MUP040c
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 15758215
Functional analysis and annotation of the virulence plasmid pMUM001 from Mycobacterium ulcerans.(Microbiology) [2005]
2uniprot[Pubmed] 14736915
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
[pubmed all]
66
 E9KTI2_9ACTO
(E9KTI2)		 
[query] 34 - 4750 (5588)
[subject] 2812 - 7227 (7646)
(6 hsp)		 0.0 3329   47%
Product
Polyketide synthase
Gene
fkbB
Tcs_11604BP_028
Organism
Streptomyces sp. KCTC 11604BP
1uniprot[Pubmed] 21175203
Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.(J. Am. Chem. Soc.) [2011]
68
 Q0R4M5_STRAT
(Q0R4M5)		 Jump to Chth_00290 
[query] 1325 - 5290 (5588)
[subject] 1689 - 5630 (5718)
(6 hsp)		 0.0 3284   49%
Product
ChlA3
Gene
 
Organism
Streptomyces antibioticus
1uniprot[Pubmed] 16793515
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.(Chem. Biol.) [2006]
70
 D6C477_9ACTO
(D6C477)		 Jump to Meili_00310 
[query] 1399 - 5290 (5588)
[subject] 1784 - 5734 (5822)
(6 hsp)		 0.0 3256   51%
Product
Modular polyketide synthase
Gene
meiA3
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12811466 [Medline] 22777186
Identification of a gene cluster encoding meilingmycin biosynthesis among multiple polyketide synthase contigs isolated from Streptomyces nanchangensis NS3226.(Arch. Microbiol.) [2003]
2uniprot[Pubmed] 20348291
Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification.(Appl. Environ. Microbiol.) [2010]
[pubmed all]
71
 D7C2B8_STRBB
(D7C2B8)		 
[query] 1374 - 4923 (5588)
[subject] 3227 - 6728 (7498)
(15 hsp)		 0.0 3244   53%
Product
Type I modular polyketide synthase
Gene
pks3-2
SBI_00651
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
72
 Q76KY0_STRHA
(Q76KY0)		 Jump to Vicen_00200 
[query] 1434 - 5290 (5588)
[subject] 1871 - 5744 (5826)
(7 hsp)		 0.0 3234   51%
Product
Polyketide synthase modules 1-3
Gene
vinP1
Organism
Streptomyces halstedii
1uniprot[Pubmed] 15112997
Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.(Chem. Biol.) [2004]
73
 Q30CS0_STRAU
(Q30CS0)		 Jump to Alip_00150 
[query] 1782 - 5286 (5588)
[subject] 34 - 3530 (3612)
(4 hsp)		 0.0 3226   52%
Product
LipPks3
Gene
lipPks3
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
76
 C5HV15_STRAT
(C5HV15)		 Jump to Indano_00170 
[query] 1780 - 5340 (5588)
[subject] 34 - 3546 (3596)
(2 hsp)		 0.0 3146   51%
Product
Polyketide synthase
Gene
idmM
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
79
 Q30CS1_STRAU
(Q30CS1)		 Jump to Alip_00140 
[query] 1 - 3543 (5588)
[subject] 1 - 3511 (3582)
(2 hsp)		 0.0 3098   52%
Product
LipPks2
Gene
lipPks2
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 16723573
Biosynthetic gene cluster for the polyenoyltetramic acid alpha-lipomycin.(Antimicrob. Agents Chemother.) [2006]
82
 E0D206_9ACTO
(E0D206)		 Jump to FD891_00050 
[query] 1782 - 5581 (5588)
[subject] 34 - 3799 (3799)
(2 hsp)		 0.0 3073   49%
Product
Polyketide synthase
Gene
gfsE
Organism
Streptomyces graminofaciens
1uniprot[Pubmed] 20589823
Cloning and characterization of the biosynthetic gene cluster of 16-membered macrolide antibiotic FD-891: involvement of a dual functional cytochrome P450 monooxygenase catalyzing epoxidation and hydroxylation.(Chembiochem) [2010]
83
 Q8CJN6_STRCO
(Q8CJN6)		 
[query] 1691 - 5296 (5588)
[subject] 925 - 4488 (4557)
(6 hsp)		 0.0 3063   51%
Product
Putative type I polyketide synthase
Gene
SCO6275
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
84
 Q82QT5_STRAW
(Q82QT5)		 
[query] 1780 - 5296 (5588)
[subject] 32 - 3486 (3564)
(2 hsp)		 0.0 3039   52%
Product
Modular polyketide synthase
Gene
pteA2
SAV418
SAV_418
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
86
 Q93H86_STRAW
(Q93H86)		 
[query] 1789 - 5296 (5588)
[subject] 1 - 3446 (3524)
(3 hsp)		 0.0 3027   52%
Product
Modular polyketide synthase
Gene
pteA2
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
87
 F8QPG1_9ACTO
(F8QPG1)		 
[query] 1 - 3545 (5588)
[subject] 1 - 3547 (3621)
(2 hsp)		 0.0 3024   52%
Product
Polyketide synthase
Gene
natD
Organism
Streptomyces sp. CS
1uniprot[Pubmed] 21614382
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS.(Mol. Biosyst.) [2011]
89
 C3VLZ7_9ACTO
(C3VLZ7)		 
[query] 2 - 3536 (5588)
[subject] 5 - 3292 (3373)
(4 hsp)		 0.0 3006   51%
Product
Polyketide synthase type I
Gene
mlaF
Organism
Streptomyces sp. MP39-85
1uniprot[Pubmed] 19854930
Insights into the Evolution of Macrolactam Biosynthesis through Cloning and Comparative Analysis of the Biosynthetic Gene Cluster for a Novel Macrocyclic Lactam, ML-449.(Appl. Environ. Microbiol.) [2010]
91
 C3VLW9_9ACTO
(C3VLW9)		 
[query] 2 - 3535 (5588)
[subject] 5 - 3294 (3377)
(4 hsp)		 0.0 3000   51%
Product
Polyketide synthase type I
Gene
becF
Organism
Streptomyces sp. DSM 21069
1uniprot[Pubmed] 19875084
Biosynthesis of macrolactam BE-14106 involves two distinct PKS systems and amino acid processing enzymes for generation of the aminoacyl starter unit.(Chem. Biol.) [2009]
92
 Q9EX53_STRCO
(Q9EX53)		 
[query] 1780 - 5298 (5588)
[subject] 32 - 3500 (3576)
(2 hsp)		 0.0 2989   50%
Product
Putative type I polyketide synthase
Gene
SCO6274
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
94
 A4FH84_SACEN
(A4FH84)		 
[query] 1782 - 5290 (5588)
[subject] 34 - 3404 (3481)
(3 hsp)		 0.0 2981   52%
Product
Type I modular polyketide synthase
Gene
SACE_4140
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
95
 Q5VKQ8_SACER
(Q5VKQ8)		 
[query] 1782 - 5290 (5588)
[subject] 34 - 3404 (3481)
(3 hsp)		 0.0 2981   52%
Product
Type I PKS
Gene
pkeAII
Organism
Saccharopolyspora erythraea
Streptomyces erythraeus
1uniprot[Pubmed] 15925898
A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea.(J. Mol. Microbiol. Biotechnol.) [2004]