| accession | DB | alignment | Evalue | Score | Ident. | link | information | pubmed |
1
|
B0BLN3_9ACTO (B0BLN3) |
|
|
0.0 |
835 |
100% |
|
- Product
- P450 oxidoreductase
- Gene
- mdpU3
- Organism
- Actinomadura madurae
|
1uniprot[Pubmed] 14528002 [Medline] 22922109 Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model.(Proc. Natl. Acad. Sci. U.S.A.) [2003] | 2uniprot[Pubmed] 17918933 Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.(J. Am. Chem. Soc.) [2007] | [pubmed all]
|
3
|
B0BLN1_9ACTO (B0BLN1) |
|
|
1e-110 |
404 |
53% |
|
- Product
- P450 oxidoreductase
- Gene
- mdpU1
- Organism
- Actinomadura madurae
|
1uniprot[Pubmed] 14528002 [Medline] 22922109 Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model.(Proc. Natl. Acad. Sci. U.S.A.) [2003] | 2uniprot[Pubmed] 17918933 Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis.(J. Am. Chem. Soc.) [2007] | [pubmed all]
|
7
|
Q825I8_STRAW (Q825I8) |
|
|
7e-86 |
322 |
46% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- cyp28
SAV7469 SAV_7469
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
8
|
Q595S4_9ACTO (Q595S4) |
|
|
2e-85 |
321 |
46% |
|
- Product
- Cytochrome P450 monooxygenase CYP105D8
- Gene
- cyp233
- Organism
- Streptomyces tubercidicus
|
1uniprot[Pubmed] 16269732 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes.(Appl. Environ. Microbiol.) [2005] | 2uniprot[Pubmed] 16269733 Biocatalytic conversion of avermectin to 4"-oxo-avermectin: heterologous expression of the ema1 cytochrome P450 monooxygenase.(Appl. Environ. Microbiol.) [2005] | [pubmed all]
|
14
|
B1VNS0_STRGG (B1VNS0) |
|
|
7e-83 |
312 |
47% |
|
- Product
- Putative cytochrome P450
- Gene
- SGR_264
- Organism
- Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
|
1uniprot[Pubmed] 18375553 Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008] |
|
15
|
B3XWK3_9ACTO (B3XWK3) |
|
|
3e-82 |
310 |
45% |
|
- Product
- Cytochrome P450 monooxygenase
- Gene
- psmA
- Organism
- Streptomyces sp. A-1544
|
1uniprot[Pubmed] 18640605 Increase in pladienolide D production rate using a Streptomyces strain overexpressing a cytochrome P450 gene.(J. Biosci. Bioeng.) [2008] |
|
16
|
Q9EWS4_STRCO (Q9EWS4) |
|
|
7e-82 |
309 |
45% |
|
- Product
- Putative cytochrome P450
- Gene
- SCO0774
- Organism
- Streptomyces coelicolor
|
1uniprot[Pubmed] 12000953 [Medline] 21996410 Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002] |
|
18
|
O85697_STRLI (O85697) |
|
|
2e-81 |
307 |
45% |
|
- Product
- Putative cytochrome P450 oxidoreductase
- Gene
-
- Organism
- Streptomyces lividans
|
1uniprot[Pubmed] 10627032 [Medline] 20090458 AUD4, a new amplifiable element from Streptomyces lividans.(Microbiology) [1999] |
|
24
|
Q79ZT5_STRAW (Q79ZT5) |
|
|
8e-79 |
299 |
44% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- pteD
SAV412 SAV_412
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
25
|
A8KXU3_FRASN (A8KXU3) |
|
|
8e-79 |
298 |
43% |
|
- Product
- Cytochrome P450
- Gene
- Franean1_3475
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
26
|
Q93H80_STRAW (Q93H80) |
|
|
8e-79 |
298 |
44% |
|
- Product
- Cytochrome P450
- Gene
- pteD
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] | 2uniprot[Pubmed] 20375018 Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis.(J. Biol. Chem.) [2010] | [pubmed all]
|
27
|
CPXH_STRGR (P26911) |
|
|
9e-79 |
298 |
43% |
|
- Product
- Cytochrome P450-SOY
- Gene
- CYP105D1
soyC
- Organism
- Streptomyces griseus
|
1uniprot[Pubmed] 1406253 [Medline] 93023839 Cloning, nucleotide sequence determination and expression of the genes encoding cytochrome P-450soy (soyC) and ferredoxinsoy (soyB) from Streptomyces griseus.(Mol. Microbiol.) [1992] |
|
28
|
F3NES9_9ACTO (F3NES9) |
|
|
2e-78 |
297 |
44% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- SGM_1643
- Organism
- Streptomyces griseoaurantiacus M045
|
1uniprot[Pubmed] 21551298 Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011] |
|
31
|
CPXE_STRGO (P18326) |
|
|
5e-76 |
289 |
42% |
|
- Product
- Cytochrome P450-SU1
CYP105A1 Cytochrome P450-CVA1
- Gene
- CYP105A1
suaC
- Organism
- Streptomyces griseolus
|
1uniprot[Pubmed] 2345149 [Medline] 90264332 Genes for two herbicide-inducible cytochromes P-450 from Streptomyces griseolus.(J. Bacteriol.) [1990] |
|
32
|
Q2L6S5_9ACTO (Q2L6S5) |
|
|
7e-75 |
285 |
43% |
|
- Product
- Cytochrome P450 type compactin 6beta-hydroxylase
- Gene
- boxA
- Organism
- Streptomyces sp. TM-7
|
1uniprot[Pubmed] 16428858 Hydroxylation of testosterone by bacterial cytochromes P450 using the Escherichia coli expression system.(Biosci. Biotechnol. Biochem.) [2006] |
|
34
|
Q8KSY0_9ACTO (Q8KSY0) |
|
|
8e-74 |
282 |
42% |
|
- Product
- Putative cytochrome P450 GrhO3
- Gene
- grhO3
- Organism
- Streptomyces sp. JP95
|
1uniprot[Pubmed] 12323376 [Medline] 22235582 A gene cluster from a marine Streptomyces encoding the biosynthesis of the aromatic spiroketal polyketide griseorhodin A.(Chem. Biol.) [2002] |
|
38
|
Q73ZY2_MYCPA (Q73ZY2) |
|
|
3e-72 |
276 |
41% |
|
- Product
- Putative uncharacterized protein
- Gene
- MAP_1469c
- Organism
- Mycobacterium paratuberculosis
|
1uniprot[Pubmed] 16116077 The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|
40
|
A8KXT8_FRASN (A8KXT8) |
|
|
4e-72 |
276 |
42% |
|
- Product
- Cytochrome P450
- Gene
- Franean1_3470
- Organism
- Frankia sp. (strain EAN1pec)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
41
|
CPS2_STRCC (Q59831) |
|
|
3e-71 |
273 |
42% |
|
- Product
- Cytochrome P450 105A3
Cytochrome P450 sca-2 Cytochrome P450 sca-2
- Gene
- CYP105A3
- Organism
- Streptomyces carbophilus
|
1uniprot[Pubmed] 7557483 [Medline] 96001248 Cloning, characterization and expression of the gene encoding cytochrome P-450sca-2 from Streptomyces carbophilus involved in production of pravastatin, a specific HMG-CoA reductase inhibitor.(Gene) [1995] | 2uniprot[Pubmed] 2509201 [Medline] 90032660 Purification and characterization of cytochrome P-450sca from Streptomyces carbophilus. ML-236B (compactin) induces a cytochrome P-450sca in Streptomyces carbophilus that hydroxylates ML-236B to pravastatin sodium (CS-514), a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase.(Eur. J. Biochem.) [1989] | 3uniprot[Pubmed] 10329788 [Medline] 99263338 Crystallization and preliminary X-ray diffraction analysis of cytochrome P450sca-2 from Streptomyces carbophilus involved in production of pravastatin sodium, a tissue-selective inhibitor of HMG-CoA reductase.(Acta Crystallogr. D) [1999] | [pubmed all]
|
42
|
Q5ENH9_PSEAH (Q5ENH9) |
|
|
4e-71 |
273 |
41% |
|
- Product
- FadC
- Gene
- fadC
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot[Pubmed] 15752735 A gene cluster for the fatty acid catabolism from Pseudonocardia autotrophica BCRC12444.(Biochem. Biophys. Res. Commun.) [2005] |
|
45
|
F4F7G4_VERMA (F4F7G4) |
|
|
1e-70 |
271 |
41% |
|
- Product
- Cytochrome P450
- Gene
- VAB18032_16485
- Organism
- Verrucosispora maris (strain AB-18-032)
|
1uniprot[Pubmed] 21551311 Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011] |
|
48
|
Q8KRU0_PSEAH (Q8KRU0) |
|
|
3e-70 |
270 |
41% |
|
- Product
- PauC
- Gene
- pauC
- Organism
- Pseudonocardia autotrophica
Amycolata autotrophica Nocardia autotrophica
|
1uniprot Molecular cloning and analysis of the gene for P-450 hydroxylase from Pseudonocardia autotrophica IFO12743.(J. Microbiol.) [2002] |
|
52
|
Q0RIE2_FRAAA (Q0RIE2) |
|
|
2e-69 |
268 |
38% |
|
- Product
- Putative cytochrome P450-SU1 (P450-CVA1) (CYP105A1)
- Gene
- FRAAL4085
- Organism
- Frankia alni (strain ACN14a)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
53
|
D3PYH2_STANL (D3PYH2) |
|
|
2e-69 |
268 |
41% |
|
- Product
- Cytochrome P450
- Gene
- Snas_1843
- Organism
- Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
|
1uniprot Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009] |
|
54
|
D2B913_STRRD (D2B913) |
|
|
2e-69 |
267 |
40% |
|
- Product
- Putative cytochrome P450
- Gene
- Sros_7070
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
58
|
Q0RID2_FRAAA (Q0RID2) |
|
|
7e-69 |
266 |
42% |
|
- Product
- Cytochrome P450 (Sca-2)
- Gene
- cytP-450sca-2
FRAAL4096
- Organism
- Frankia alni (strain ACN14a)
|
1uniprot[Pubmed] 17151343 Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007] |
|
61
|
C7MXK5_SACVD (C7MXK5) |
|
|
1e-68 |
265 |
41% |
|
- Product
- Cytochrome P450
- Gene
- Svir_22760
- Organism
- Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
|
1uniprot Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009] |
|
62
|
D8I293_AMYMU (D8I293) |
|
|
1e-68 |
265 |
40% |
|
- Product
- Cytochrome P450
- Gene
- AMED_0875
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
64
|
D2B704_STRRD (D2B704) |
|
|
2e-68 |
264 |
40% |
|
- Product
- Putative cytochrome P450
- Gene
- Sros_4934
- Organism
- Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
|
1uniprot Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010] |
|
65
|
D3Q1N8_STANL (D3Q1N8) |
|
|
3e-68 |
263 |
38% |
|
- Product
- Cytochrome P450
- Gene
- Snas_0166
- Organism
- Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
|
1uniprot Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009] |
|
66
|
Q156A0_AMYOR (Q156A0) |
|
|
6e-68 |
263 |
39% |
|
- Product
- Epothilone b hydroxylase
- Gene
- ebh
- Organism
- Amycolatopsis orientalis
Nocardia orientalis
|
1uniprot[Pubmed] 16972046 Cloning and expression of a cytochrome P450 hydroxylase gene from Amycolatopsis orientalis: hydroxylation of epothilone B for the production of epothilone F.(J. Ind. Microbiol. Biotechnol.) [2007] |
|
68
|
D5SJF4_STRCL (D5SJF4) |
|
|
1e-67 |
261 |
42% |
|
- Product
- Cytochrome P450
- Gene
- SCLAV_p0558
- Organism
- Streptomyces clavuligerus ATCC 27064
|
1uniprot The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010] |
|
70
|
C6WQG7_ACTMD (C6WQG7) |
|
|
1e-67 |
261 |
39% |
|
- Product
- Cytochrome P450
- Gene
- Amir_2894
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
71
|
D8I6M4_AMYMU (D8I6M4) |
|
|
2e-67 |
261 |
38% |
|
- Product
- Cytochrome P450
- Gene
- AMED_7228
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
73
|
A6YRR3_STRVG (A6YRR3) |
|
|
3e-67 |
260 |
38% |
|
- Product
- Cytochrome P450 monooxygenase 105
- Gene
-
- Organism
- Streptomyces virginiae
|
1uniprot[Pubmed] 19376895 Characterization of P450 FcpC, the Enzyme Responsible for Bioconversion of Diosgenone to Isonuatigenone in Streptomyces virginiae IBL-14.(Appl. Environ. Microbiol.) [2009] |
|
74
|
F2RDD2_STRVP (F2RDD2) |
|
|
4e-67 |
259 |
38% |
|
- Product
- Putative cytochrome P450 hydroxylase
- Gene
- SVEN_6138
- Organism
- Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
|
1uniprot[Pubmed] 21463507 Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011] |
|
78
|
Q742Y1_MYCPA (Q742Y1) |
|
|
6e-67 |
259 |
39% |
|
- Product
- Putative uncharacterized protein
- Gene
- MAP_0704
- Organism
- Mycobacterium paratuberculosis
|
1uniprot[Pubmed] 16116077 The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005] |
|
82
|
D8I294_AMYMU (D8I294) |
|
|
2e-66 |
258 |
39% |
|
- Product
- Cytochrome P450
- Gene
- AMED_0876
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
86
|
E4NBF9_KITSK (E4NBF9) |
|
|
6e-66 |
256 |
39% |
|
- Product
- Putative cytochrome P450
- Gene
- KSE_27280
- Organism
- Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
|
1uniprot[Pubmed] 21059706 Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010] |
|
87
|
C6W8T3_ACTMD (C6W8T3) |
|
|
6e-66 |
256 |
38% |
|
- Product
- Cytochrome P450
- Gene
- Amir_3276
- Organism
- Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
|
1uniprot Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009] |
|
88
|
D7C2C0_STRBB (D7C2C0) |
|
|
7e-66 |
256 |
41% |
|
- Product
- Cytochrome P450
- Gene
- cyp11
SBI_00653
- Organism
- Streptomyces bingchenggensis (strain BCW-1)
|
1uniprot[Pubmed] 20581206 Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010] |
|
91
|
A4FHI7_SACEN (A4FHI7) |
|
|
1e-65 |
254 |
39% |
|
- Product
- Cytochrome P450 hydroxylase
- Gene
- pteC
SACE_4243
- Organism
- Saccharopolyspora erythraea (strain NRRL 23338)
|
1uniprot[Pubmed] 17369815 Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007] |
|
92
|
Q82MP9_STRAW (Q82MP9) |
|
|
3e-65 |
254 |
40% |
|
- Product
- Putative cytochrome P450
- Gene
- cyp7
SAV1611 SAV_1611
- Organism
- Streptomyces avermitilis
|
1uniprot[Pubmed] 11572948 [Medline] 21477403 Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001] |
|
93
|
D8I8M5_AMYMU (D8I8M5) |
|
|
3e-65 |
254 |
40% |
|
- Product
- Cytochrome P450
- Gene
- AMED_3577
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
94
|
Q6V1N2_9ACTO (Q6V1N2) |
|
|
3e-65 |
253 |
38% |
|
- Product
- PlmT4
- Gene
- plmT4
- Organism
- Streptomyces sp. HK803
|
1uniprot[Pubmed] 12819191 [Medline] 22841069 Enhancement and selective production of phoslactomycin B, a protein phosphatase IIa inhibitor, through identification and engineering of the corresponding biosynthetic gene cluster.(J. Biol. Chem.) [2003] |
|
95
|
D0U2E9_STRPT (D0U2E9) |
|
|
3e-65 |
253 |
40% |
|
- Product
- Hydroxylase
- Gene
-
- Organism
- Streptomyces platensis subsp. rosaceus
|
1uniprot[Pubmed] 19726666 iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.(J. Biol. Chem.) [2009] |
|
97
|
D8I768_AMYMU (D8I768) |
|
|
4e-65 |
253 |
39% |
|
- Product
- Cytochrome P450
- Gene
- AMED_3473
- Organism
- Amycolatopsis mediterranei (strain U-32)
|
1uniprot[Pubmed] 20567260 Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010] |
|
99
|
D3PXG6_STANL (D3PXG6) |
|
|
5e-65 |
253 |
39% |
|
- Product
- Cytochrome P450
- Gene
- Snas_1731
- Organism
- Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
|
1uniprot Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009] |
|