BLAST table : Salino3_00220

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
 D9W5P2_9ACTO
(D9W5P2)		 
[query] 1 - 128 (128)
[subject] 43 - 170 (170)
 2e-50 201   75% Predicted protein SSNG_07472 Streptomyces sp. C
2
 C5HV18_STRAT
(C5HV18)		 Jump to Indano_00200 
[query] 3 - 127 (128)
[subject] 2422 - 2546 (2547)
 2e-20 102   42% Polyketide synthase idmP Streptomyces antibioticus
3
 B1W484_STRGG
(B1W484)		 
[query] 1 - 126 (128)
[subject] 1 - 128 (133)
 1e-19 100   43% Putative ketosteroid isomerase SGR_6072 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
4
 Q6F497_STRGR
(Q6F497)		 
[query] 1 - 126 (128)
[subject] 1 - 128 (133)
 1e-19 100   43% Putative ketosteroid isomerase orf2-AdBS4 Streptomyces griseus
5
 B6ZK72_STRLS
(B6ZK72)		 Jump to Lasal_00210 
[query] 3 - 128 (128)
[subject] 135 - 277 (282)
(2 hsp)		 4e-15 85.1 33% Epoxide hydrolase lsd19 Streptomyces lasaliensis
6
 B5M9L7_STRLS
(B5M9L7)		 Jump to Lasal2_00250 
[query] 3 - 128 (128)
[subject] 135 - 277 (282)
(2 hsp)		 4e-15 84.7 33% Epoxide hydrolase lasB Streptomyces lasaliensis
7
 E0KCN5_STRVO
(E0KCN5)		 
[query] 1 - 128 (128)
[subject] 1 - 143 (145)
 1e-14 83.6 32% Nuclear transport factor 2 StrviDRAFT_0010 Streptomyces violaceusniger Tu 4113
8
 Q27W61_STRVO
(Q27W61)		 Jump to Niger_00140 
[query] 1 - 128 (128)
[subject] 1 - 143 (145)
 2e-14 82.4 32% NigBI Streptomyces violaceoniger
9
 D7F1M3_9ACTO
(D7F1M3)		 
[query] 1 - 128 (128)
[subject] 1 - 128 (139)
 4e-14 81.6 34% Epoxide hydrolase tsnB Streptomyces longisporoflavus
10
 D9W5P8_9ACTO
(D9W5P8)		 
[query] 1 - 126 (128)
[subject] 97 - 237 (243)
 2e-13 79.3 30% NigBI SSNG_07478 Streptomyces sp. C
11
 D9W5P7_9ACTO
(D9W5P7)		 
[query] 1 - 128 (128)
[subject] 1 - 143 (149)
 5e-12 74.3 29% Predicted protein SSNG_07477 Streptomyces sp. C
12
 Q1MX77_9ACTO
(Q1MX77)		 Jump to Tetrn_00120 
[query] 1 - 128 (128)
[subject] 1 - 128 (141)
 7e-12 73.9 34% Probable epoxide hydrolase tmnB Streptomyces sp. NRRL 11266
13
 Q6SH72_9BACT
(Q6SH72)		 
[query] 1 - 127 (128)
[subject] 1 - 122 (125)
 1e-11 73.6 34% Steroid delta-isomerase ksi
MBMO_EBAC000-63A02.25		 uncultured marine bacterium 442 5.3.3.1
14
 A0Z4P3_9GAMM
(A0Z4P3)		 
[query] 1 - 127 (128)
[subject] 1 - 122 (125)
 1e-11 73.6 34% Nuclear transport factor 2 MGP2080_10543 marine gamma proteobacterium HTCC2080
15
 Q27W62_STRVO
(Q27W62)		 Jump to Niger_00130 
[query] 1 - 128 (128)
[subject] 1 - 123 (155)
 1e-11 73.2 31% NigBIII Streptomyces violaceoniger
16
 E0KCN4_STRVO
(E0KCN4)		 
[query] 1 - 128 (128)
[subject] 1 - 123 (155)
 2e-11 72.8 31% Putative uncharacterized protein StrviDRAFT_0009 Streptomyces violaceusniger Tu 4113
17
 F6EPH3_9MYCO
(F6EPH3)		 
[query] 1 - 128 (128)
[subject] 1 - 122 (123)
 3e-11 72   33% Putative 3-ketosteroid 5-isomerase AS9A_0954 Amycolicicoccus subflavus DQS3-9A1
18
 B0TTY6_SHEHH
(B0TTY6)		 
[query] 1 - 122 (128)
[subject] 1 - 116 (131)
 1e-10 69.7 33% Nuclear transport factor 2 Shal_2145 Shewanella halifaxensis (strain HAW-EB4)
19
 Q471Q2_CUPPJ
(Q471Q2)		 
[query] 1 - 126 (128)
[subject] 2 - 123 (126)
 2e-10 69.7 29% Nuclear transport factor 2 Reut_A1514 Cupriavidus pinatubonensis (strain JMP134 / LMG 1197)
Alcaligenes eutrophus
Ralstonia eutropha
20
 A8H4K7_SHEPA
(A8H4K7)		 
[query] 1 - 122 (128)
[subject] 1 - 116 (123)
 6e-10 67.8 32% Nuclear transport factor 2 Spea_2174 Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)
21
 SDIS_COMTE
(P00947)		 
[query] 1 - 126 (128)
[subject] 1 - 121 (125)
 1e-09 66.6 30% Steroid Delta-isomerase
Delta(5)-3-ketosteroid isomerase		 ksi Comamonas testosteroni
Pseudomonas testosteroni		 5.3.3.1
22
 A4FI35_SACEN
(A4FI35)		 
[query] 1 - 126 (128)
[subject] 1 - 123 (124)
 2e-09 66.2 33% Steroid delta-isomerase SACE_4441 Saccharopolyspora erythraea (strain NRRL 23338) 5.3.3.1
23
 Q846W7_STRCM
(Q846W7)		 Jump to Monen_00240 
[query] 3 - 128 (128)
[subject] 2 - 142 (144)
 3e-09 65.1 26% Probable monensin biosynthesis isomerase monBI Streptomyces cinnamonensis
24
 D7BSM4_STRBB
(D7BSM4)		 
[query] 1 - 126 (128)
[subject] 1 - 141 (313)
(2 hsp)		 4e-09 64.7 28% Putative ketosteroid isomerase nanI
SBI_08403		 Streptomyces bingchenggensis (strain BCW-1)
25
 E0D2V1_COMTE
(E0D2V1)		 
[query] 1 - 126 (128)
[subject] 1 - 121 (125)
 6e-09 64.3 30% 3-ketosteroiod isomerase Comamonas testosteroni
Pseudomonas testosteroni
26
 D8DDX1_COMTE
(D8DDX1)		 
[query] 10 - 126 (128)
[subject] 4 - 115 (119)
 7e-09 63.9 32% Putative uncharacterized protein CTS44_25169 Comamonas testosteroni S44
27
 SDIS_NOCSI
(P77816)		 
[query] 8 - 126 (128)
[subject] 6 - 118 (123)
 8e-09 63.9 33% Steroid Delta-isomerase
Delta(5)-3-ketosteroid isomerase		 ksdI Nocardioides simplex
Arthrobacter simplex		 5.3.3.1
28
 A0QCP8_MYCA1
(A0QCP8)		 
[query] 1 - 128 (128)
[subject] 1 - 122 (123)
 1e-08 63.2 31% Steroid delta-isomerase MAV_1444 Mycobacterium avium (strain 104) 5.3.3.1
29
 Q7WTD9_9ACTO
(Q7WTD9)		 Jump to Nanch_00240 
[query] 1 - 126 (128)
[subject] 1 - 141 (313)
(2 hsp)		 1e-08 63.2 29% NanI nanI Streptomyces nanchangensis
30
 B7X4V2_COMTE
(B7X4V2)		 
[query] 1 - 126 (128)
[subject] 1 - 121 (125)
 2e-08 63.2 29% Steroid Delta-isomerase CtesDRAFT_PD3678 Comamonas testosteroni KF-1 5.3.3.1
31
 D0J389_COMT2
(D0J389)		 
[query] 10 - 126 (128)
[subject] 4 - 115 (119)
 2e-08 62.8 32% Putative uncharacterized protein CtCNB1_1323 Comamonas testosteroni (strain CNB-2)
32
 Q73X32_MYCPA
(Q73X32)		 
[query] 1 - 128 (128)
[subject] 1 - 122 (123)
 2e-08 62.4 30% Putative uncharacterized protein MAP_2478 Mycobacterium paratuberculosis
33
 F7P514_MYCPA
(F7P514)		 
[query] 1 - 128 (128)
[subject] 1 - 122 (123)
 2e-08 62.4 30% NTF2 domain-containing protein MAPs_35910 Mycobacterium avium subsp. paratuberculosis S397
34
 Q8ETH3_OCEIH
(Q8ETH3)		 
[query] 1 - 126 (128)
[subject] 1 - 122 (124)
 3e-08 62   28% Steroid delta-isomerase OB0288 Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) 5.3.3.1
35
 A4XEU5_NOVAD
(A4XEU5)		 
[query] 8 - 127 (128)
[subject] 11 - 126 (128)
 6e-08 60.8 30% Nuclear transport factor 2 Saro_3596 Novosphingobium aromaticivorans (strain DSM 12444)
36
 C1B7K2_RHOOB
(C1B7K2)		 
[query] 8 - 126 (128)
[subject] 9 - 121 (124)
 1e-07 60.5 30% Delta(5)-3-ketosteroid isomerase ksi
ROP_34080		 Rhodococcus opacus (strain B4) 5.3.3.1
37
 D9V191_9ACTO
(D9V191)		 
[query] 6 - 127 (128)
[subject] 6 - 121 (128)
 1e-07 60.1 30% Steroid delta-isomerase SSMG_04622 Streptomyces sp. AA4
38
 F8GQY7_CUPNE
(F8GQY7)		 
[query] 1 - 126 (128)
[subject] 1 - 122 (125)
 1e-07 60.1 28% Steroid delta-isomerase CNE_2c05470 Cupriavidus necator N-1 5.3.3.1
39
 Q0K3M5_CUPNH
(Q0K3M5)		 
[query] 1 - 126 (128)
[subject] 1 - 122 (125)
 1e-07 60.1 27% Steroid delta-isomerase H16_B0602 Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Ralstonia eutropha		 5.3.3.1
40
 Q0SAM4_RHOSR
(Q0SAM4)		 
[query] 8 - 126 (128)
[subject] 9 - 121 (124)
 1e-07 59.7 30% Steroid delta-isomerase RHA1_ro03609 Rhodococcus sp. (strain RHA1) 5.3.3.1
41
 F1YPF4_9ACTO
(F1YPF4)		 
[query] 8 - 126 (128)
[subject] 5 - 116 (119)
 2e-07 59.3 34% Delta(5)-3-ketosteroid isomerase SCNU_19045 Gordonia neofelifaecis NRRL B-59395
42
 C5NS17_PSERE
(C5NS17)		 
[query] 1 - 126 (128)
[subject] 1 - 123 (129)
 2e-07 59.3 31% 3-ketosteroid-5-isomerase ORF24 Pseudomonas resinovorans
43
 A1SNR6_NOCSJ
(A1SNR6)		 
[query] 8 - 126 (128)
[subject] 9 - 121 (124)
 3e-07 58.5 32% Nuclear transport factor 2 Noca_3954 Nocardioides sp. (strain BAA-499 / JS614)
44
 E6TKZ1_MYCSR
(E6TKZ1)		 
[query] 10 - 126 (128)
[subject] 11 - 119 (123)
 6e-07 57.8 32% NTF2 domain-containing protein Mspyr1_14770 Mycobacterium sp. (strain Spyr1)
45
 F3L4Q1_9GAMM
(F3L4Q1)		 
[query] 3 - 122 (128)
[subject] 2 - 116 (122)
 1e-06 57   29% Nuclear transport factor 2 IMCC3088_2652 gamma proteobacterium IMCC3088
46
 E1VGB4_9GAMM
(E1VGB4)		 
[query] 3 - 122 (128)
[subject] 2 - 112 (117)
 1e-06 57   30% Steroid delta-isomerase ksi
HDN1F_02730		 gamma proteobacterium HdN1 5.3.3.1
47
 Q5Z059_NOCFA
(Q5Z059)		 
[query] 5 - 121 (128)
[subject] 3 - 115 (126)
 1e-06 56.6 29% Putative 3-ketosteroid-5-isomerase NFA_13370 Nocardia farcinica
48
 A4T9B5_MYCGI
(A4T9B5)		 
[query] 10 - 126 (128)
[subject] 11 - 119 (123)
 2e-06 56.2 31% Nuclear transport factor 2 Mflv_2053 Mycobacterium gilvum (strain PYR-GCK)
Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)
49
 B1MKK2_MYCA9
(B1MKK2)		 
[query] 10 - 126 (128)
[subject] 11 - 121 (124)
 3e-06 55.5 33% Putative uncharacterized protein MAB_1206 Mycobacterium abscessus (strain ATCC 19977 / DSM 44196)
50
 B2AIK2_CUPTR
(B2AIK2)		 
[query] 8 - 126 (128)
[subject] 2 - 116 (119)
 3e-06 55.5 28% Steroid delta-isomerase RALTA_B0406 Cupriavidus taiwanensis (strain R1 / LMG 19424)
Ralstonia taiwanensis (strain LMG 19424)		 5.3.3.1
51
 F5YUG8_9MYCO
(F5YUG8)		 
[query] 5 - 126 (128)
[subject] 9 - 124 (127)
 3e-06 55.5 30% Putative uncharacterized protein JDM601_1031 Mycobacterium sp. JDM601
52
 D7CC05_STRBB
(D7CC05)		 
[query] 1 - 125 (128)
[subject] 1 - 143 (150)
 4e-06 55.1 27% Putative uncharacterized protein SBI_01379 Streptomyces bingchenggensis (strain BCW-1)
53
 C0ZTA9_RHOE4
(C0ZTA9)		 
[query] 14 - 126 (128)
[subject] 19 - 125 (128)
 5e-06 54.7 32% Probable delta(5)-3-ketosteroid isomerase ksi
RER_13740		 Rhodococcus erythropolis (strain PR4 / NBRC 100887) 5.3.3.1
54
 C3JL73_RHOER
(C3JL73)		 
[query] 8 - 126 (128)
[subject] 9 - 121 (124)
 5e-06 54.7 31% Steroid Delta-isomerase RHOER0001_5290 Rhodococcus erythropolis SK121 5.3.3.1
55
 C3JRL9_RHOER
(C3JRL9)		 
[query] 14 - 126 (128)
[subject] 19 - 125 (128)
 6e-06 54.3 32% Steroid Delta-isomerase RHOER0001_4815 Rhodococcus erythropolis SK121 5.3.3.1
56
 C0ZVK8_RHOE4
(C0ZVK8)		 
[query] 8 - 126 (128)
[subject] 9 - 121 (124)
 6e-06 54.3 30% Putative delta(5)-3-ketosteroid isomerase RER_59940 Rhodococcus erythropolis (strain PR4 / NBRC 100887) 5.3.3.1
57
 Q5YXK1_NOCFA
(Q5YXK1)		 
[query] 8 - 126 (128)
[subject] 8 - 120 (123)
 8e-06 53.9 27% Putative 3-ketosteroid 5-isomerase NFA_22430 Nocardia farcinica
58
 SDIS_PSEPU
(P07445)		 
[query] 5 - 128 (128)
[subject] 7 - 127 (131)
 8e-06 53.9 27% Steroid Delta-isomerase
Delta(5)-3-ketosteroid isomerase		 ksi Pseudomonas putida
Arthrobacter siderocapsulatus		 5.3.3.1
59
 Q1B4E0_MYCSS
(Q1B4E0)		 
[query] 8 - 126 (128)
[subject] 6 - 116 (119)
 1e-05 53.1 28% Nuclear transport factor 2 Mmcs_4139 Mycobacterium sp. (strain MCS)
60
 A1UKP8_MYCSK
(A1UKP8)		 
[query] 8 - 126 (128)
[subject] 6 - 116 (119)
 1e-05 53.1 28% Nuclear transport factor 2 Mkms_4214 Mycobacterium sp. (strain KMS)
61
 A0R2W6_MYCS2
(A0R2W6)		 
[query] 2 - 126 (128)
[subject] 3 - 121 (124)
 1e-05 53.1 28% Steroid delta-isomerase MSMEG_5258 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 5.3.3.1
62
 D0L985_GORB4
(D0L985)		 
[query] 11 - 126 (128)
[subject] 16 - 126 (129)
 2e-05 52.8 28% Steroid delta-isomerase Gbro_4817 Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667)
Rhodococcus bronchialis
63
 A1TE39_MYCVP
(A1TE39)		 
[query] 10 - 126 (128)
[subject] 11 - 119 (123)
 2e-05 52.8 30% Nuclear transport factor 2 Mvan_4664 Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
64
 A3Q4R4_MYCSJ
(A3Q4R4)		 
[query] 8 - 126 (128)
[subject] 6 - 116 (119)
 2e-05 52.4 28% Nuclear transport factor 2 Mjls_4370 Mycobacterium sp. (strain JLS)
65
 E9T850_COREQ
(E9T850)		 
[query] 8 - 126 (128)
[subject] 9 - 121 (124)
 3e-05 52   29% Steroid delta-isomerase (Delta(5)-3-ketosteroidisomerase) HMPREF0724_14956 Rhodococcus equi ATCC 33707 5.3.3.1
66
 D5PFQ7_9MYCO
(D5PFQ7)		 
[query] 1 - 126 (128)
[subject] 1 - 120 (123)
 3e-05 52   26% Steroid delta-isomerase ksdI
HMPREF0591_5001		 Mycobacterium parascrofulaceum ATCC BAA-614 5.3.3.1
67
 E6JB80_9ACTO
(E6JB80)		 
[query] 14 - 121 (128)
[subject] 18 - 121 (127)
 5e-05 51.2 33% Nuclear transport factor 2 ES5_12460 Dietzia cinnamea P4
68
 Q73WF5_MYCPA
(Q73WF5)		 
[query] 8 - 125 (128)
[subject] 11 - 122 (127)
 7e-05 50.8 28% Putative uncharacterized protein MAP_2705c Mycobacterium paratuberculosis
69
 A0QC17_MYCA1
(A0QC17)		 
[query] 8 - 125 (128)
[subject] 11 - 122 (127)
 7e-05 50.8 28% Steroid delta-isomerase MAV_1209 Mycobacterium avium (strain 104) 5.3.3.1
70
 F7PAY1_MYCPA
(F7PAY1)		 
[query] 8 - 125 (128)
[subject] 11 - 122 (127)
 7e-05 50.8 28% NTF2 domain-containing protein MAPs_09870 Mycobacterium avium subsp. paratuberculosis S397
71
 A5VBH5_SPHWW
(A5VBH5)		 
[query] 1 - 126 (128)
[subject] 1 - 119 (122)
 0.0001 50.4 25% Nuclear transport factor 2 Swit_3295 Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)
72
 Q846W8_STRCM
(Q846W8)		 Jump to Monen_00230 
[query] 1 - 126 (128)
[subject] 1 - 121 (140)
 0.0001 50.4 25% Probable monensin biosynthesis isomerase monBII Streptomyces cinnamonensis
73
 E4WB21_RHOE1
(E4WB21)		 
[query] 1 - 128 (128)
[subject] 1 - 122 (123)
 0.0001 50.1 29% Putative steroid DELTA-isomerase REQ_46990 Rhodococcus equi (strain 103S)
Corynebacterium equi
74
 E9T7Q7_COREQ
(E9T7Q7)		 
[query] 1 - 128 (128)
[subject] 1 - 122 (123)
 0.0001 50.1 29% Steroid delta-isomerase (Delta(5)-3-ketosteroidisomerase) HMPREF0724_14806 Rhodococcus equi ATCC 33707 5.3.3.1
75
 E4WB73_RHOE1
(E4WB73)		 
[query] 8 - 126 (128)
[subject] 9 - 121 (124)
 0.0002 49.7 28% Putative 3-ketosteroid 5-isomerase REQ_00120 Rhodococcus equi (strain 103S)
Corynebacterium equi
76
 F1YL66_9ACTO
(F1YL66)		 
[query] 5 - 126 (128)
[subject] 12 - 128 (131)
 0.0007 47.4 27% Steroid delta-isomerase SCNU_13118 Gordonia neofelifaecis NRRL B-59395
77
 B2HT68_MYCMM
(B2HT68)		 
[query] 5 - 126 (128)
[subject] 9 - 124 (127)
 0.0008 47.4 25% Putative uncharacterized protein MMAR_4382 Mycobacterium marinum (strain ATCC BAA-535 / M)
78
 A0PKS7_MYCUA
(A0PKS7)		 
[query] 5 - 126 (128)
[subject] 9 - 124 (127)
 0.0008 47.4 25% Putative uncharacterized protein MUL_0195 Mycobacterium ulcerans (strain Agy99)
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
2
 C5HV18_STRAT
(C5HV18)		 Jump to Indano_00200 
[query] 3 - 127 (128)
[subject] 2422 - 2546 (2547)
 2e-20 102   42%
Product
Polyketide synthase
Gene
idmP
Organism
Streptomyces antibioticus
1uniprot
Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167.(Chembiochem) [2009]
3
 B1W484_STRGG
(B1W484)		 
[query] 1 - 126 (128)
[subject] 1 - 128 (133)
 1e-19 100   43%
Product
Putative ketosteroid isomerase
Gene
SGR_6072
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
4
 Q6F497_STRGR
(Q6F497)		 
[query] 1 - 126 (128)
[subject] 1 - 128 (133)
 1e-19 100   43%
Product
Putative ketosteroid isomerase
Gene
orf2-AdBS4
Organism
Streptomyces griseus
1uniprot[Pubmed] 15228534
DNA-binding specificity of AdpA, a transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus.(Mol. Microbiol.) [2004]
5
 B6ZK72_STRLS
(B6ZK72)		 Jump to Lasal_00210 
[query] 3 - 128 (128)
[subject] 135 - 277 (282)
(2 hsp)		 4e-15 85.1 33%
Product
Epoxide hydrolase
Gene
lsd19
Organism
Streptomyces lasaliensis
1uniprot[Pubmed] 19129623
Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.(Biosci. Biotechnol. Biochem.) [2009]
2uniprot[Pubmed] 18710235
Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.(J. Am. Chem. Soc.) [2008]
[pubmed all]
8
 Q27W61_STRVO
(Q27W61)		 Jump to Niger_00140 
[query] 1 - 128 (128)
[subject] 1 - 143 (145)
 2e-14 82.4 32%
Product
NigBI
Gene
 
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17584617
Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007]
14
 A0Z4P3_9GAMM
(A0Z4P3)		 
[query] 1 - 127 (128)
[subject] 1 - 122 (125)
 1e-11 73.6 34%
Product
Nuclear transport factor 2
Gene
MGP2080_10543
Organism
marine gamma proteobacterium HTCC2080
1uniprot[Pubmed] 20472793
Genome sequences of strains HTCC2148 and HTCC2080, belonging to the OM60/NOR5 clade of the Gammaproteobacteria.(J. Bacteriol.) [2010]
15
 Q27W62_STRVO
(Q27W62)		 Jump to Niger_00130 
[query] 1 - 128 (128)
[subject] 1 - 123 (155)
 1e-11 73.2 31%
Product
NigBIII
Gene
 
Organism
Streptomyces violaceoniger
1uniprot[Pubmed] 17584617
Insights into Polyether Biosynthesis from Analysis of the Nigericin Biosynthetic Gene Cluster in Streptomyces sp. DSM4137.(Chem. Biol.) [2007]
21
 SDIS_COMTE
(P00947)		 
[query] 1 - 126 (128)
[subject] 1 - 121 (125)
 1e-09 66.6 30%
Product
Steroid Delta-isomerase
Delta(5)-3-ketosteroid isomerase
Gene
ksi
Organism
Comamonas testosteroni
Pseudomonas testosteroni
1uniprot[Pubmed] 3224818 [Medline] 89137982
Nucleotide sequence of the gene for the delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni.(Gene) [1988]
2uniprot[Pubmed] 3480517 [Medline] 88097394
Isolation and sequencing of the gene encoding delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni: overexpression of the protein.(Proc. Natl. Acad. Sci. U.S.A.) [1987]
3uniprot[Pubmed] 5135313 [Medline] 72085988
The amino acid sequence of delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni.(J. Biol. Chem.) [1971]
4uniprot[Pubmed] 4753764 [Medline] 74032505
Molecular weight determination and structural studies of Pseudomonas testosteroni delta 5 leads to 4-3-oxosteroid isomerase (EC 5.3.3.1).(FEBS Lett.) [1973]
5uniprot[Pubmed] 9369474 [Medline] 98039133
High-resolution crystal structures of delta5-3-ketosteroid isomerase with and without a reaction intermediate analogue.(Biochemistry) [1997]
6uniprot[Pubmed] 9103200 [Medline] 97258944
Solution structure of 3-oxo-delta5-steroid isomerase.(Science) [1997]
7uniprot[Pubmed] 9778345
Solution structure of delta 5-3-ketosteroid isomerase complexed with the steroid 19-nortestosterone hemisuccinate.(Biochemistry) [1998]
8uniprot[Pubmed] 10551849 [Medline] 20020257
Crystal structure of delta(5)-3-ketosteroid isomerase from Pseudomonas testosteroni in complex with equilenin settles the correct hydrogen bonding scheme for transition state stabilization.(J. Biol. Chem.) [1999]
9uniprot[Pubmed] 12852789
The conserved cis-Pro39 residue plays a crucial role in the proper positioning of the catalytic base Asp38 in ketosteroid isomerase from Comamonas testosteroni.(Biochem. J.) [2003]
10uniprot[Pubmed] 12734184
Origin of the different pH activity profile in two homologous ketosteroid isomerases.(J. Biol. Chem.) [2003]
[pubmed all]
22
 A4FI35_SACEN
(A4FI35)		 
[query] 1 - 126 (128)
[subject] 1 - 123 (124)
 2e-09 66.2 33%
Product
Steroid delta-isomerase
Gene
SACE_4441
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
23
 Q846W7_STRCM
(Q846W7)		 Jump to Monen_00240 
[query] 3 - 128 (128)
[subject] 2 - 142 (144)
 3e-09 65.1 26%
Product
Probable monensin biosynthesis isomerase
Gene
monBI
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 12940979 [Medline] 22823264
Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003]
2uniprot
The gene cluster for monensin biosynthesis. [1999]
24
 D7BSM4_STRBB
(D7BSM4)		 
[query] 1 - 126 (128)
[subject] 1 - 141 (313)
(2 hsp)		 4e-09 64.7 28%
Product
Putative ketosteroid isomerase
Gene
nanI
SBI_08403
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
27
 SDIS_NOCSI
(P77816)		 
[query] 8 - 126 (128)
[subject] 6 - 118 (123)
 8e-09 63.9 33%
Product
Steroid Delta-isomerase
Delta(5)-3-ketosteroid isomerase
Gene
ksdI
Organism
Nocardioides simplex
Arthrobacter simplex
1uniprot[Pubmed] 7596291 [Medline] 95319331
Molecular cloning, expression in Streptomyces lividans, and analysis of a gene cluster from Arthrobacter simplex encoding 3-ketosteroid-delta 1-dehydrogenase, 3-ketosteroid-delta 5-isomerase and a hypothetical regulatory protein.(Mol. Microbiol.) [1995]
29
 Q7WTD9_9ACTO
(Q7WTD9)		 Jump to Nanch_00240 
[query] 1 - 126 (128)
[subject] 1 - 141 (313)
(2 hsp)		 1e-08 63.2 29%
Product
NanI
Gene
nanI
Organism
Streptomyces nanchangensis
1uniprot[Pubmed] 12770825 [Medline] 22654646
A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin.(Chem. Biol.) [2003]
30
 B7X4V2_COMTE
(B7X4V2)		 
[query] 1 - 126 (128)
[subject] 1 - 121 (125)
 2e-08 63.2 29%
Product
Steroid Delta-isomerase
Gene
CtesDRAFT_PD3678
Organism
Comamonas testosteroni KF-1
1uniprot[Pubmed] 15240283
Mineralization of individual congeners of linear alkylbenzenesulfonate by defined pairs of heterotrophic bacteria.(Appl. Environ. Microbiol.) [2004]
31
 D0J389_COMT2
(D0J389)		 
[query] 10 - 126 (128)
[subject] 4 - 115 (119)
 2e-08 62.8 32%
Product
Putative uncharacterized protein
Gene
CtCNB1_1323
Organism
Comamonas testosteroni (strain CNB-2)
1uniprot[Pubmed] 19734336
The complete genome of Comamonas testosteroni reveals its genetic adaptations to changing environments.(Appl. Environ. Microbiol.) [2009]
32
 Q73X32_MYCPA
(Q73X32)		 
[query] 1 - 128 (128)
[subject] 1 - 122 (123)
 2e-08 62.4 30%
Product
Putative uncharacterized protein
Gene
MAP_2478
Organism
Mycobacterium paratuberculosis
1uniprot[Pubmed] 16116077
The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005]
34
 Q8ETH3_OCEIH
(Q8ETH3)		 
[query] 1 - 126 (128)
[subject] 1 - 122 (124)
 3e-08 62   28%
Product
Steroid delta-isomerase
Gene
OB0288
Organism
Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831)
1uniprot[Pubmed] 12235376 [Medline] 22220767
Genome sequence of Oceanobacillus iheyensis isolated from the Iheya Ridge and its unexpected adaptive capabilities to extreme environments.(Nucleic Acids Res.) [2002]
39
 Q0K3M5_CUPNH
(Q0K3M5)		 
[query] 1 - 126 (128)
[subject] 1 - 122 (125)
 1e-07 60.1 27%
Product
Steroid delta-isomerase
Gene
H16_B0602
Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Ralstonia eutropha
1uniprot[Pubmed] 16964242
Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia eutropha H16.(Nat. Biotechnol.) [2006]
40
 Q0SAM4_RHOSR
(Q0SAM4)		 
[query] 8 - 126 (128)
[subject] 9 - 121 (124)
 1e-07 59.7 30%
Product
Steroid delta-isomerase
Gene
RHA1_ro03609
Organism
Rhodococcus sp. (strain RHA1)
1uniprot[Pubmed] 17030794
The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006]
45
 F3L4Q1_9GAMM
(F3L4Q1)		 
[query] 3 - 122 (128)
[subject] 2 - 116 (122)
 1e-06 57   29%
Product
Nuclear transport factor 2
Gene
IMCC3088_2652
Organism
gamma proteobacterium IMCC3088
1uniprot[Pubmed] 21551310
Genome Sequence of Strain IMCC3088, a Proteorhodopsin-Containing Marine Bacterium Belonging to the OM60/NOR5 Clade.(J. Bacteriol.) [2011]
46
 E1VGB4_9GAMM
(E1VGB4)		 
[query] 3 - 122 (128)
[subject] 2 - 112 (117)
 1e-06 57   30%
Product
Steroid delta-isomerase
Gene
ksi
HDN1F_02730
Organism
gamma proteobacterium HdN1
1uniprot
Alkane degradation by a new type of denitrifying bacterium with possible involvement of the electron acceptor in substrate activation.(Environ. Microbiol.) [2010]
47
 Q5Z059_NOCFA
(Q5Z059)		 
[query] 5 - 121 (128)
[subject] 3 - 115 (126)
 1e-06 56.6 29%
Product
Putative 3-ketosteroid-5-isomerase
Gene
NFA_13370
Organism
Nocardia farcinica
1uniprot[Pubmed] 15466710
The complete genomic sequence of Nocardia farcinica IFM 10152.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
50
 B2AIK2_CUPTR
(B2AIK2)		 
[query] 8 - 126 (128)
[subject] 2 - 116 (119)
 3e-06 55.5 28%
Product
Steroid delta-isomerase
Gene
RALTA_B0406
Organism
Cupriavidus taiwanensis (strain R1 / LMG 19424)
Ralstonia taiwanensis (strain LMG 19424)
1uniprot[Pubmed] 18490699
Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and comparative genomics of rhizobia.(Genome Res.) [2008]
52
 D7CC05_STRBB
(D7CC05)		 
[query] 1 - 125 (128)
[subject] 1 - 143 (150)
 4e-06 55.1 27%
Product
Putative uncharacterized protein
Gene
SBI_01379
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
53
 C0ZTA9_RHOE4
(C0ZTA9)		 
[query] 14 - 126 (128)
[subject] 19 - 125 (128)
 5e-06 54.7 32%
Product
Probable delta(5)-3-ketosteroid isomerase
Gene
ksi
RER_13740
Organism
Rhodococcus erythropolis (strain PR4 / NBRC 100887)
1uniprot
Sequence analysis of three plasmids harboured in Rhodococcus erythropolis strain PR4.(Environ. Microbiol.) [2006]
56
 C0ZVK8_RHOE4
(C0ZVK8)		 
[query] 8 - 126 (128)
[subject] 9 - 121 (124)
 6e-06 54.3 30%
Product
Putative delta(5)-3-ketosteroid isomerase
Gene
RER_59940
Organism
Rhodococcus erythropolis (strain PR4 / NBRC 100887)
1uniprot
Sequence analysis of three plasmids harboured in Rhodococcus erythropolis strain PR4.(Environ. Microbiol.) [2006]
57
 Q5YXK1_NOCFA
(Q5YXK1)		 
[query] 8 - 126 (128)
[subject] 8 - 120 (123)
 8e-06 53.9 27%
Product
Putative 3-ketosteroid 5-isomerase
Gene
NFA_22430
Organism
Nocardia farcinica
1uniprot[Pubmed] 15466710
The complete genomic sequence of Nocardia farcinica IFM 10152.(Proc. Natl. Acad. Sci. U.S.A.) [2004]
58
 SDIS_PSEPU
(P07445)		 
[query] 5 - 128 (128)
[subject] 7 - 127 (131)
 8e-06 53.9 27%
Product
Steroid Delta-isomerase
Delta(5)-3-ketosteroid isomerase
Gene
ksi
Organism
Pseudomonas putida
Arthrobacter siderocapsulatus
1uniprot[Pubmed] 7961420 [Medline] 95050228
Cloning, nucleotide sequence, and overexpression of the gene coding for delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.(J. Bacteriol.) [1994]
2uniprot[Pubmed] 3700400 [Medline] 86196068
The amino acid sequence of a delta 5-3-oxosteroid isomerase from Pseudomonas putida biotype B.(J. Biol. Chem.) [1986]
3uniprot[Pubmed] 9369474 [Medline] 98039133
High-resolution crystal structures of delta5-3-ketosteroid isomerase with and without a reaction intermediate analogue.(Biochemistry) [1997]
4uniprot[Pubmed] 10529226
Roles of active site aromatic residues in catalysis by ketosteroid isomerase from Pseudomonas putida biotype B.(Biochemistry) [1999]
5uniprot[Pubmed] 10653633
Asp-99 donates a hydrogen bond not to Tyr-14 but to the steroid directly in the catalytic mechanism of delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.(Biochemistry) [2000]
6uniprot[Pubmed] 11007792
Detection of large pKa perturbations of an inhibitor and a catalytic group at an enzyme active site, a mechanistic basis for catalytic power of many enzymes.(J. Biol. Chem.) [2000]
7uniprot[Pubmed] 11695900
Maintenance of alpha-helical structures by phenyl rings in the active-site tyrosine triad contributes to catalysis and stability of ketosteroid isomerase from Pseudomonas putida biotype B.(Biochemistry) [2001]
8uniprot[Pubmed] 15819891
Small exterior hydrophobic cluster contributes to conformational stability and steroid binding in ketosteroid isomerase from Pseudomonas putida biotype B.(FEBS J.) [2005]
[pubmed all]
68
 Q73WF5_MYCPA
(Q73WF5)		 
[query] 8 - 125 (128)
[subject] 11 - 122 (127)
 7e-05 50.8 28%
Product
Putative uncharacterized protein
Gene
MAP_2705c
Organism
Mycobacterium paratuberculosis
1uniprot[Pubmed] 16116077
The complete genome sequence of Mycobacterium avium subspecies paratuberculosis.(Proc. Natl. Acad. Sci. U.S.A.) [2005]
72
 Q846W8_STRCM
(Q846W8)		 Jump to Monen_00230 
[query] 1 - 126 (128)
[subject] 1 - 121 (140)
 0.0001 50.4 25%
Product
Probable monensin biosynthesis isomerase
Gene
monBII
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 12940979 [Medline] 22823264
Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.(Mol. Microbiol.) [2003]
2uniprot
The gene cluster for monensin biosynthesis. [1999]
73
 E4WB21_RHOE1
(E4WB21)		 
[query] 1 - 128 (128)
[subject] 1 - 122 (123)
 0.0001 50.1 29%
Product
Putative steroid DELTA-isomerase
Gene
REQ_46990
Organism
Rhodococcus equi (strain 103S)
Corynebacterium equi
1uniprot[Pubmed] 20941392
The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions.(PLoS Genet.) [2010]
75
 E4WB73_RHOE1
(E4WB73)		 
[query] 8 - 126 (128)
[subject] 9 - 121 (124)
 0.0002 49.7 28%
Product
Putative 3-ketosteroid 5-isomerase
Gene
REQ_00120
Organism
Rhodococcus equi (strain 103S)
Corynebacterium equi
1uniprot[Pubmed] 20941392
The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions.(PLoS Genet.) [2010]
77
 B2HT68_MYCMM
(B2HT68)		 
[query] 5 - 126 (128)
[subject] 9 - 124 (127)
 0.0008 47.4 25%
Product
Putative uncharacterized protein
Gene
MMAR_4382
Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
1uniprot[Pubmed] 18403782
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis.(Genome Res.) [2008]
78
 A0PKS7_MYCUA
(A0PKS7)		 
[query] 5 - 126 (128)
[subject] 9 - 124 (127)
 0.0008 47.4 25%
Product
Putative uncharacterized protein
Gene
MUL_0195
Organism
Mycobacterium ulcerans (strain Agy99)
1uniprot[Pubmed] 17210928
Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer.(Genome Res.) [2007]