Crypto_00010 Crypto_00010   Crypto_00030 Crypto_00030

Crypto_00020 : CDS information

close this sectionLocation

Organism
StrainATCC 53789
Entry nameCryptophycin 1
Contig
Start / Stop / Direction18,814 / 29,223 / + [in whole cluster]
18,814 / 29,223 / + [in contig]
Location18814..29223 [in whole cluster]
18814..29223 [in contig]
TypeCDS
Length10,410 bp (3,469 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category1.1 PKS
Productpolyketide synthase
Product (GenBank)CrpB
Gene
Gene (GenBank)crpB
EC number
Keyword
Note
Note (GenBank)
  • polyketide synthase; KS-AT-KR-ACP-KS-AT-DH-KR-ACP
Reference
ACC
PmId
[17240975] Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from cyanobionts. (ACS Chem Biol. , 2006)
[17240971] Cryptophycin anticancer drugs revisited. (ACS Chem Biol. , 2006)
comment
[PMID: 17240975](2006)
comment in: [PMID: 17240971](2006)

cryptophycin生合成遺伝子を同定した論文。
Supplementary Table 1.
CrpB: type I PKS

cryptophycin1のaglycon形成には2つのPKSと2つのNRPSが関与。
PKS(crpA-B)はunitA部分(sigma-hydroxy-phenyloctenoic acid)の形成を担う。

crpBはmodular type I PKSのmodule 2-3をコードする。

close this sectionPKS/NRPS Module

2 malonyl-CoA
3 malonyl-CoA
KS45..420
AT579..900
KR1241..1420
ACP1524..1594
KS1619..1998
AT2154..2470
DH2518..2688
KR3082..3261
ACP3365..3434

close this sectionSequence

selected fasta
>polyketide synthase [CrpB]
MDMNINRRNTSNSKQADSLSPTKQALLALERMQSKLDALEYAKTEPIAIIGMGCRFPGGA
STPKGFWEVLKNGVDAITQVPPNRWNLDNYYDPNPESPGKIYTPYGGFIELLDQFDANLF
GISPREAIHLDPQQRLLLEVTWEAIENALINPTELNGSQTSVFTGICGNDYYQRVIAQDS
EQIDAYVVSGNAHSTASGRISYILGLLGPSLAVDTACSSSLVSVHLACSSLRRGESNLAL
AGGVNRIISPEVSIAFSKARMLSFNGRCKTFDASADGFVRGEGCGVVVLKRLSDALTDKD
NILAVIRGSAINQDGHTSGLTVPNGPSQQAVIRQALENGGVEPANISYFEAHGTGTSLGD
PIEVGALGTVFGTSHSKEQPLIVGSVKTNIGHLEAAAGVAGLIKIVLQLQNQQIVPSLHF
NQPNPYINWSELPVKIPTQISPWPTNGKSRIAGVSSFGFSGTNAHVILEEAPTQQSQVKD
SDLGKHPWHILTLSAKCEKALQEMIQSYEEFLSNDNTATIADICFSAHISRSHFDYRLAL
IAPSTEKLRQKLKVFQKNPEDTLGVVRGQVDSKKLAKIVFLFTGQGSQYINMGRQLYETQ
PVFRQTLEQCEQILQPYLKKSILDIIYPEDNQKLNSSIIDQTAYTQVALFAIEYALYKLW
ESWGIKPDVVMGHSVGEYVAATVAGIFSLEDGLKLIAHRGRLMQQLSSGGEMLSVMASIE
KVNQLIAPYSQKVAIASINGPQSIVISGEAEAIGAVQNSLEAEDIKTKRLQVSHAFHSHL
MEPMLADFEAVASEITYNQPNIPLVSNVTGARAENSIATASYWVNHVRQPVKFAQSMDTL
QQEGYSIFLEIGPKPTLLGMGRQCLPEDVGVWLPSLRPGQEDWQQMLQSLAELYVHGVKV
DWLGFDKDYSRSKVVLPTYPFQRQRYWIESTESQSQKAAYSSCETKSTPIFDLLIHGNIQ
QLAQQIEKIGKFSPEQVNLLPEFLEVLVKQHQKQLIIETTKDFLYQVQWKPLVDTQPKTS
IKPSHWLIFADTTAVGEKLVQQLQSHHCECSLVYRSDCYRKLDEGTYQLNPTEAQEFEQL
IQAIGENSKLPLLHVINLWSLDIQGTQDLTTTTLKQAQLWGCGTVLQLVKVLTKTKSVAK
LWLVTRGAQLVKSQTESVCVAASPLWGMGRVISLEHPQLWGGMVDLDPISPESEAYTLLQ
LLVNSNQLEDHLALRADNLYFARLVKQSLKPYDSVSLKDNATYLITGGLGALGLHTARWM
VQQGARHLVLTGRKQPNLEAQQIIEELQKLGAQILVLCGDISDEVDATTIFSEIEASLPT
LKGVINAAGVLDDALLHSMSWEQFTQVMAPKVQGAWHLHNLTQNKALDFFVCFSSMASLV
GSPGQGNYAAANAFMDALAHHRRGMGLPGLSINWGPWAQAGMAASLDNRNRDRMVASGIT
PLTPEQGLQVLGQLLEQSLPQVGVLSVQWSVFQEKFSFGNQIPLLLELLGETESQQKAFR
TKTKQNELLKRLESLPCKERYYVLRTEIQSEVAKVLALNDSQLPGFEQGFFDLGMDSLMA
VELRNRITQLLKVTLPSTLSFDFPNIEQLTKYISSQILDLSTSNDGQQPEQKVKAAEHEP
IAIIGMGCSLPGGANTPEKFWELLHSGTSAREEIPAQRWDVNSYYDPDREAAGKMVTRYG
HFISGVDQFDPEFFGISPREATAMDPQHRLLLEVSWQALERAGQKVERLSSEPVGVFVGN
DGHDYEQLMQKHLEQEPNSTFGTYTCTGNSPSSASGRLAYTFGFTGPTVTIDTACSSSLV
AIHQACNSIRLGECQMAIAGGVKLHLTPSSYIFTSRAGMISPDGLCKTFDISADGYGRGE
GCGMVVLKSLSQAQADGDPILALILGSAVNQDGPSSGLTVPNGQSQQKLILQALKQARVE
PADISYLEAHGTGTSLGDPIEVNAAAAVLGLQRSPSQPLWIGTVKTNIGHLESAAGVSGL
IKVVLSLQHQQIPANLHLQEPNPKIDWQPWLQVPQALTPWVGSKGRLAGVSSFGFTGTNA
HVVLSETPAAIASSTVEYERPLHLLQLSAKNDLALAQLAQRYSDHLKTHLEQDLRDICFT
ANSSRLAHKHRLAVVASNRKELQQKLGNFGTDSERMDLVTGQVSSSQLTKVAMLFTGQGS
QYVGMGRQLYQTQPTFKQFVDQCAQILENYLDKPLLEILDVAQVQENVLAQTAYTQVALF
AIEYALYKLWESWGIKPDVVMGHSAGEYVAATVAGIFSLEDGLKLIAHRGRLMQQLPSGG
EMLSVMASIEKVNQLIAPYSQKVAIASINGPQSIVISGEAEAIGAVQNSLEAEDIKTKRL
QVSHAFHSHLMEPMLADFEAVASEITYNQPNIPLVSNVTGARAENSIATASYWVNHVRQP
VKFAQSMDTLQQEGYSIFLEIGPKPTLLGMGRQCLPEDVGVWLPSLKPGQEDWQQMLQSL
AELYVHGVKVDWLGFDKDYSRSKVVLPTYPFQRQRYWIETNNNLIHQKQFLSNHKNLHPL
LGQRLHLAALEQQIRFECQISASQPTYLQHHCVFSQPVFPAAAYLEIALAAGSILFNSDD
LILEDIAIQKVLILSKDEINTIQIVLNLQLVQSYKFQIFSLDINTNSSEPKWILHIEGKI
LVGNKDPQLETTNLKAIKDEYNQQILPTEFYQKFEEWGLNYGSSFQAVKQLWHSEGKALG
EIQLPETEVNVATLYQLHPILLDASFQVLAAVMGKTDNQETYLPLEIKRLQIYRSGSNSL
WTQVEIGATETNKQTLSGKVCLLDEQGIVVARVEGLTLLRTSREALLRNIEPKFNNWLYQ
IHWQTQSISPHNQSIDLTKSGSWLLFSPPTGIGKHLVESLEQQGWHCILVTPGENYQQLE
SQHYQINPNHPEEFLHLLQSSLEQQPPLRGIIHLWSLDSTIALRTGAQELQKSQELGCGS
VLHLVQALVKNQDMESAPLWLVTQGSQSVGNESLPIQFQQTPLWGLGRVIAQEHRELQCR
CLDLDPTMEDSQTVAALLEELLSPGDENQIAYCQGVRHVARLERQQKMSTSTQSGLQISS
QQPFQLKLSEYKSLDNLIQAEASYLITGGLGALGLKTAEWMVQQGVKYLVLTGRRQPSAK
AQQTIEQLQKAGAQVLVLCGDISQQENVARIIESIKVSLPALRGIIHAAGILDDGLLLNM
NWEKFTQVMAPKVQGAWHLHNLTQNLPLDFFVCFSSMASILGSPGQGNYAAANAFMDGLA
HHRRGMGLPGLSINWGPWAQEGMAANLDSPHQDRMVSKGMTFLSSEQGLQVLGQLLEQSI
PQVGVLPIQWSVFQEQFSFGNQIPLLSQLVKESKSQQKALKTKTKHNEFLEQLKAALPRE
REKLLIIYIKDEISQVLSLSTSQIDMQQPLNTMGLDSLMAVELHNRLQTDLLVDISIVKF
IEDISIVDLATEVNEQLSQVAQNQGVESENNGQLYQSNRKENERIRGEL
selected fasta
>polyketide synthase [CrpB]
ATGGACATGAATATTAATAGGCGTAATACTTCTAACTCAAAACAAGCTGACTCTCTATCG
CCAACTAAACAAGCGCTACTTGCCTTAGAGAGGATGCAATCCAAACTGGACGCTTTAGAA
TATGCCAAGACTGAACCAATAGCAATCATTGGAATGGGCTGCCGCTTCCCCGGAGGTGCA
TCTACTCCGAAAGGGTTTTGGGAAGTTTTAAAAAACGGAGTAGATGCCATCACTCAAGTA
CCCCCAAATCGATGGAATCTTGATAATTACTATGACCCAAACCCAGAATCTCCTGGTAAA
ATTTATACTCCTTATGGGGGATTCATTGAGCTTCTAGATCAGTTTGATGCTAATTTGTTC
GGTATTTCTCCTAGAGAAGCGATTCATTTAGACCCTCAACAGCGATTACTATTAGAAGTT
ACTTGGGAAGCCATAGAGAATGCTCTAATAAATCCGACTGAACTTAACGGAAGCCAAACA
AGTGTTTTTACTGGCATTTGTGGCAATGATTATTACCAACGCGTAATTGCTCAAGACTCA
GAACAAATTGATGCTTATGTTGTATCAGGTAATGCTCATAGTACGGCATCGGGGCGAATT
TCCTATATTTTAGGGTTACTCGGACCTTCTTTAGCAGTAGACACAGCCTGCTCCTCTTCT
TTGGTAAGTGTGCATTTAGCTTGCTCCAGTTTAAGAAGAGGAGAATCTAACCTAGCATTG
GCAGGAGGAGTGAATAGAATAATTTCTCCAGAGGTGAGTATAGCTTTTTCTAAAGCCCGT
ATGTTGTCCTTTAATGGGCGATGTAAGACTTTTGACGCTAGTGCAGATGGTTTTGTTCGT
GGTGAAGGATGCGGTGTTGTTGTACTCAAACGTTTATCAGATGCATTAACTGATAAAGAC
AATATCTTGGCTGTGATTCGGGGAAGCGCCATTAACCAAGATGGTCACACCAGTGGTTTA
ACGGTTCCTAACGGTCCTTCTCAACAAGCAGTAATTCGCCAAGCTTTGGAAAATGGGGGA
GTAGAACCGGCAAATATTAGTTATTTTGAAGCTCATGGTACAGGGACATCCTTGGGAGAT
CCGATTGAAGTTGGAGCCCTAGGGACTGTATTTGGCACAAGCCACTCTAAAGAGCAACCT
TTAATAGTTGGCTCAGTAAAAACTAACATTGGACACTTAGAGGCAGCAGCAGGAGTTGCT
GGTTTGATCAAAATAGTCCTACAACTGCAAAATCAACAAATAGTACCATCACTGCATTTT
AACCAGCCTAATCCTTATATTAATTGGTCGGAATTACCAGTAAAAATTCCGACGCAGATT
AGCCCTTGGCCAACAAATGGAAAAAGCCGTATAGCTGGAGTTAGTTCTTTTGGGTTTAGT
GGAACTAATGCTCATGTAATTTTAGAAGAAGCTCCGACTCAACAGTCCCAGGTTAAGGAT
TCTGATTTGGGTAAGCATCCTTGGCACATACTAACCTTATCTGCCAAATGTGAAAAAGCA
CTGCAAGAAATGATCCAAAGCTATGAAGAATTTTTAAGTAATGATAATACAGCAACAATT
GCTGATATATGTTTTAGTGCTCATATAAGTCGCAGCCATTTTGACTATCGCCTTGCTTTA
ATAGCTCCATCAACCGAGAAATTGCGCCAAAAATTAAAGGTTTTTCAAAAAAACCCGGAA
GATACTCTAGGAGTGGTGAGGGGTCAAGTTGACAGTAAAAAGTTAGCGAAAATAGTATTT
TTATTCACTGGTCAGGGCTCCCAATATATCAATATGGGAAGACAACTATATGAAACACAA
CCTGTCTTCCGTCAAACCTTAGAGCAGTGCGAACAAATTCTACAACCATATTTAAAAAAA
TCGATTTTAGATATTATTTACCCAGAAGATAATCAAAAATTAAACAGTAGTATTATTGAC
CAAACCGCCTATACCCAAGTAGCTTTATTTGCAATAGAATATGCTCTTTATAAACTATGG
GAATCCTGGGGAATAAAACCGGATGTGGTGATGGGGCATAGTGTTGGGGAATATGTGGCA
GCCACAGTAGCAGGAATATTTAGTTTAGAAGATGGTTTAAAACTGATTGCTCATAGAGGA
AGACTAATGCAACAGTTATCCTCTGGGGGTGAAATGTTATCTGTAATGGCTTCAATTGAA
AAGGTAAATCAACTAATTGCACCATACTCTCAAAAAGTAGCGATCGCATCGATTAACGGA
CCCCAAAGCATTGTCATTTCTGGTGAGGCAGAAGCAATTGGAGCGGTTCAAAATAGCTTA
GAAGCAGAAGACATTAAGACAAAACGACTGCAAGTATCCCACGCATTCCATTCACATTTG
ATGGAACCAATGTTGGCGGACTTTGAAGCAGTAGCATCAGAAATAACCTACAATCAACCA
AATATTCCATTAGTATCAAATGTAACGGGAGCTAGGGCAGAGAATAGTATTGCCACAGCA
AGCTATTGGGTAAATCATGTCCGGCAACCGGTAAAATTTGCCCAAAGTATGGACACATTA
CAGCAAGAAGGTTATTCCATCTTCTTAGAAATTGGACCCAAACCAACTTTGTTAGGCATG
GGAAGACAGTGCTTGCCAGAAGATGTGGGAGTTTGGTTGCCTTCTTTGAGACCAGGTCAA
GAAGACTGGCAGCAAATGCTACAAAGTTTGGCTGAACTATATGTGCATGGAGTTAAAGTT
GATTGGTTAGGGTTTGATAAAGATTATTCTCGTAGCAAGGTAGTATTGCCGACTTATCCC
TTTCAACGGCAACGTTATTGGATTGAGAGCACGGAAAGTCAAAGCCAAAAAGCAGCTTAT
TCCTCTTGTGAAACAAAGAGTACTCCAATTTTCGATTTGCTAATCCATGGGAATATCCAA
CAGTTGGCTCAACAAATAGAAAAAATTGGTAAATTTTCTCCAGAACAAGTCAATCTCCTG
CCAGAATTTCTAGAAGTATTAGTAAAACAGCACCAGAAACAACTAATTATAGAAACTACC
AAAGATTTCTTGTACCAAGTACAGTGGAAACCTTTAGTTGATACCCAACCCAAGACAAGC
ATTAAACCTAGCCATTGGTTAATTTTTGCAGACACCACCGCAGTAGGGGAAAAATTAGTT
CAGCAATTGCAATCGCACCATTGTGAATGTAGTTTAGTTTATCGAAGTGATTGCTACCGA
AAACTAGACGAAGGTACTTATCAACTCAATCCCACAGAGGCTCAAGAGTTTGAACAACTA
ATTCAAGCTATCGGGGAAAATAGCAAATTACCCTTACTCCATGTGATTAATTTGTGGAGT
TTAGATATTCAAGGAACGCAAGACTTAACAACCACAACTTTAAAACAAGCACAACTTTGG
GGATGTGGCACGGTGCTACAACTAGTGAAAGTGCTAACTAAAACCAAAAGTGTAGCCAAA
CTGTGGTTAGTGACTCGAGGTGCTCAATTAGTCAAATCCCAAACCGAATCAGTCTGTGTG
GCTGCATCACCCTTGTGGGGAATGGGGCGAGTAATATCTCTGGAGCATCCCCAACTGTGG
GGTGGAATGGTAGATTTAGACCCAATTTCTCCAGAATCAGAAGCATACACACTACTACAA
CTTCTAGTAAATTCTAACCAATTAGAAGACCATCTAGCTTTACGGGCAGATAATTTATAC
TTTGCTCGTTTAGTCAAGCAATCTCTCAAACCATATGATTCTGTGTCACTCAAGGATAAT
GCGACATATTTAATAACAGGAGGATTGGGAGCTTTAGGATTACACACAGCGCGGTGGATG
GTTCAACAAGGAGCAAGACATTTAGTACTCACCGGACGTAAGCAGCCTAACCTTGAAGCT
CAACAAATCATTGAAGAACTGCAAAAGCTAGGGGCACAAATATTAGTCTTATGTGGGGAT
ATCTCCGATGAAGTTGATGCGACTACAATTTTTTCAGAAATTGAAGCATCTTTACCGACC
CTAAAAGGTGTAATTAATGCTGCTGGGGTATTAGATGATGCCTTGCTCCACTCTATGAGT
TGGGAACAATTTACACAGGTGATGGCACCGAAAGTACAAGGGGCTTGGCATCTTCATAAT
TTAACTCAGAATAAAGCTTTGGACTTTTTTGTTTGTTTCTCCTCGATGGCTTCATTGGTA
GGTTCACCCGGTCAAGGAAATTATGCCGCAGCTAATGCTTTTATGGATGCTTTAGCCCAT
CATCGACGGGGAATGGGTTTACCAGGTTTAAGTATTAACTGGGGACCTTGGGCACAAGCA
GGAATGGCAGCAAGCTTAGATAATCGTAATAGAGATCGAATGGTTGCCTCTGGAATCACT
CCTTTGACTCCAGAGCAGGGATTGCAGGTTCTAGGACAACTACTCGAACAGTCCTTACCA
CAGGTAGGAGTTTTATCGGTTCAATGGTCAGTGTTCCAAGAGAAATTTAGTTTTGGTAAT
CAAATACCATTACTTTTGGAATTGCTAGGAGAAACCGAATCACAACAAAAAGCCTTTAGA
ACAAAGACAAAGCAAAATGAGCTTTTAAAACGATTGGAATCTTTGCCTTGTAAAGAGCGC
TACTATGTATTGAGAACTGAAATTCAGAGTGAAGTAGCCAAAGTATTGGCGCTCAATGAT
TCCCAACTACCTGGTTTTGAGCAAGGATTCTTTGACTTGGGTATGGACTCATTAATGGCA
GTGGAATTACGTAACCGCATCACCCAATTACTAAAGGTGACATTACCCTCAACCCTAAGC
TTTGACTTTCCCAATATTGAACAACTAACTAAGTATATAAGCTCTCAAATACTAGACCTG
AGTACCTCGAATGATGGTCAGCAGCCAGAACAAAAAGTAAAAGCTGCAGAACATGAACCC
ATAGCGATTATAGGTATGGGATGTTCCTTACCTGGTGGAGCAAACACCCCAGAAAAATTC
TGGGAATTATTGCATTCAGGTACTAGTGCCCGTGAAGAAATTCCAGCACAGCGATGGGAC
GTCAATAGCTACTATGACCCAGACCGAGAAGCCGCAGGTAAAATGGTCACCCGTTACGGT
CACTTTATTAGTGGAGTAGATCAATTTGACCCAGAATTTTTTGGCATCTCTCCGAGGGAA
GCAACAGCCATGGATCCCCAACATCGGTTGCTACTGGAAGTAAGTTGGCAAGCCTTAGAG
CGAGCCGGACAAAAGGTGGAACGTCTATCATCCGAACCCGTTGGGGTATTTGTGGGTAAC
GATGGACATGACTACGAACAACTGATGCAAAAGCATTTAGAGCAAGAGCCCAACAGTACC
TTTGGCACCTATACATGCACTGGTAACAGTCCTTCGAGTGCGTCAGGACGTTTGGCTTAT
ACATTTGGGTTCACGGGACCAACAGTAACCATTGATACCGCCTGTTCTTCTTCCTTAGTG
GCGATTCATCAAGCTTGCAACAGCATACGCCTGGGAGAATGTCAGATGGCAATTGCTGGG
GGAGTGAAACTCCATCTAACTCCTAGTAGCTATATTTTTACTTCCCGAGCCGGAATGATT
TCCCCAGACGGATTGTGCAAAACCTTTGATATATCAGCGGATGGTTATGGTCGGGGAGAA
GGCTGTGGTATGGTGGTGCTCAAGTCTTTGAGTCAAGCCCAAGCAGACGGTGACCCAATT
TTAGCCTTGATTCTGGGCAGTGCGGTGAACCAAGATGGACCCAGTAGTGGCTTAACAGTG
CCTAATGGCCAGTCCCAACAAAAATTGATTTTACAAGCACTCAAACAAGCTCGGGTAGAA
CCGGCAGATATTAGCTACTTAGAAGCCCATGGTACGGGTACATCTTTGGGAGACCCCATA
GAGGTAAATGCAGCAGCAGCAGTACTAGGGCTCCAACGTTCACCAAGTCAGCCCTTGTGG
ATAGGTACGGTAAAGACAAATATTGGGCATTTGGAGTCGGCAGCGGGGGTATCGGGACTA
ATTAAGGTAGTACTATCTCTACAGCATCAGCAAATACCTGCCAATTTACATCTGCAAGAG
CCTAACCCCAAGATTGACTGGCAACCTTGGTTACAGGTACCTCAAGCTTTGACCCCTTGG
GTTGGGTCGAAAGGTAGGTTGGCGGGGGTAAGTTCTTTTGGGTTTACGGGTACTAATGCC
CATGTGGTGCTATCGGAAACCCCTGCTGCCATTGCCAGTTCTACAGTAGAGTATGAGCGT
CCACTACATCTGTTGCAGTTGTCAGCCAAAAATGACTTGGCTTTGGCACAGCTAGCCCAA
CGCTATAGTGACCATTTAAAAACGCACCTAGAGCAGGACTTAAGGGATATCTGCTTTACT
GCCAATAGTAGTAGGTTGGCTCACAAGCATCGTCTGGCGGTGGTCGCGAGCAATCGAAAA
GAGTTGCAACAAAAGCTGGGTAACTTTGGTACAGATTCAGAAAGGATGGATTTGGTAACT
GGACAAGTCAGTAGTAGTCAGTTGACCAAAGTTGCAATGCTTTTCACTGGTCAAGGGTCT
CAATATGTGGGTATGGGTCGCCAGCTTTACCAAACCCAACCGACCTTCAAACAATTTGTG
GATCAATGTGCCCAAATATTAGAAAACTACTTAGACAAACCTTTATTAGAAATACTTGAT
GTCGCTCAAGTACAGGAAAATGTCCTAGCTCAAACCGCCTATACCCAAGTAGCTTTATTT
GCAATAGAATATGCTCTTTATAAACTATGGGAATCCTGGGGAATAAAACCGGATGTGGTT
ATGGGGCATAGTGCTGGGGAATATGTGGCAGCCACAGTAGCAGGAATATTTAGTTTAGAA
GATGGTTTAAAACTGATTGCTCATAGAGGAAGACTAATGCAACAGTTACCCTCTGGGGGT
GAAATGTTATCTGTAATGGCTTCAATTGAAAAGGTAAATCAACTAATTGCACCATACTCT
CAAAAAGTAGCGATCGCATCGATTAACGGACCCCAAAGCATTGTCATTTCTGGTGAGGCA
GAAGCAATTGGAGCGGTTCAAAATAGCTTAGAAGCAGAAGACATTAAGACAAAACGACTG
CAAGTATCCCACGCATTCCATTCACATTTGATGGAACCAATGTTGGCGGACTTTGAAGCA
GTAGCATCAGAAATAACCTACAATCAACCAAATATTCCATTAGTATCAAATGTAACGGGA
GCTAGGGCAGAGAATAGTATTGCCACAGCAAGCTATTGGGTAAATCATGTCCGGCAACCG
GTGAAATTTGCCCAAAGTATGGACACATTACAGCAAGAAGGTTATTCCATCTTCTTAGAA
ATTGGACCCAAACCAACTTTGTTAGGCATGGGAAGACAGTGCTTGCCAGAAGATGTGGGA
GTTTGGTTGCCTTCTTTGAAACCAGGTCAAGAAGACTGGCAGCAAATGCTACAAAGTTTG
GCTGAACTATATGTGCATGGAGTTAAAGTTGATTGGTTAGGGTTTGATAAAGATTATTCT
CGTAGCAAGGTAGTATTGCCGACTTATCCCTTTCAACGGCAACGTTATTGGATTGAGACA
AATAATAATCTAATACATCAAAAACAGTTTTTATCAAATCATAAAAATCTTCACCCTCTA
CTCGGTCAAAGATTACATTTAGCAGCCTTAGAACAGCAAATTCGTTTTGAATGTCAAATT
AGTGCTTCTCAACCAACTTACCTGCAACACCACTGTGTTTTTTCTCAACCTGTTTTCCCA
GCAGCAGCTTACTTGGAAATAGCCTTAGCAGCAGGTTCAATTTTATTCAATTCAGATGAT
TTAATCCTAGAAGATATAGCAATCCAAAAAGTATTAATTTTATCAAAGGATGAAATTAAT
ACAATTCAGATAGTTTTAAATTTACAGTTAGTACAAAGCTATAAATTCCAAATTTTCAGT
TTGGATATAAACACTAATTCTTCAGAACCTAAATGGATTCTACATATTGAAGGAAAAATA
TTAGTAGGTAATAAAGACCCCCAATTAGAAACAACAAACTTAAAAGCGATTAAAGACGAG
TATAACCAACAGATATTACCTACTGAATTCTACCAAAAATTTGAAGAATGGGGTCTTAAT
TACGGTTCTTCTTTCCAAGCCGTTAAACAACTGTGGCACAGCGAAGGAAAAGCACTAGGT
GAAATTCAGTTACCAGAAACTGAGGTGAATGTTGCAACTTTATACCAACTGCACCCAATT
CTTTTAGATGCTAGCTTCCAGGTGTTAGCAGCAGTTATGGGTAAAACGGACAACCAAGAA
ACTTATTTGCCATTGGAAATAAAACGACTACAAATTTATCGGAGTGGTAGTAATAGTTTG
TGGACTCAAGTAGAGATAGGTGCAACAGAAACTAATAAACAAACTTTGAGCGGTAAAGTT
TGTTTATTGGATGAACAAGGAATAGTAGTAGCAAGAGTTGAAGGTTTAACTTTATTACGT
ACTTCTCGCGAGGCTTTGTTGCGTAATATTGAACCAAAATTTAATAATTGGTTATATCAA
ATCCATTGGCAAACCCAATCAATTTCACCCCATAACCAATCAATTGACTTAACAAAATCA
GGTAGCTGGTTATTGTTTTCCCCACCCACAGGTATAGGCAAACATCTGGTAGAATCCTTA
GAACAACAAGGTTGGCATTGTATATTAGTAACACCAGGGGAAAATTACCAGCAGTTAGAA
TCTCAACATTATCAAATCAACCCCAACCATCCTGAGGAATTCCTGCACCTATTGCAATCA
AGCTTGGAGCAGCAACCCCCATTACGAGGAATTATTCACCTGTGGAGTTTGGACTCAACA
ATAGCACTAAGGACTGGGGCACAGGAGTTGCAAAAATCCCAAGAACTGGGCTGTGGCAGC
GTACTTCATTTAGTCCAAGCCTTAGTAAAAAATCAAGATATGGAAAGTGCCCCATTATGG
TTAGTGACTCAAGGCTCACAATCTGTGGGTAATGAGTCCCTTCCTATACAATTCCAACAA
ACACCTTTATGGGGGTTAGGTCGAGTAATTGCCCAGGAACATAGGGAATTACAATGCCGG
TGTTTAGACTTAGATCCAACTATGGAAGATTCCCAAACAGTAGCTGCTTTGTTAGAGGAA
CTATTATCTCCTGGTGATGAAAACCAAATTGCTTACTGTCAAGGGGTACGTCACGTTGCC
CGGTTAGAGCGGCAACAAAAAATGAGTACATCTACACAGTCCGGATTACAAATTTCCTCG
CAACAACCATTTCAACTGAAGCTATCAGAATATAAGTCTTTAGACAACCTAATCCAAGCC
GAAGCCAGTTACTTAATTACCGGAGGTCTGGGAGCACTGGGGTTAAAAACCGCTGAGTGG
ATGGTACAACAAGGGGTCAAATATTTAGTACTTACCGGACGTAGGCAGCCATCAGCAAAA
GCTCAACAAACCATTGAACAATTACAGAAGGCAGGAGCGCAAGTATTAGTCCTGTGTGGA
GATATTTCCCAACAAGAAAATGTGGCAAGAATTATAGAGTCAATCAAAGTATCTTTGCCA
GCATTACGAGGAATAATTCATGCTGCTGGGATATTGGATGATGGTTTGCTGTTAAACATG
AATTGGGAAAAATTTACACAGGTGATGGCACCAAAAGTACAAGGGGCTTGGCATTTGCAT
AATTTGACTCAGAATCTACCTTTGGACTTTTTTGTTTGTTTTTCCTCTATGGCTTCAATA
TTGGGTTCGCCTGGTCAAGGGAATTATGCTGCTGCTAATGCTTTCATGGATGGTTTAGCC
CATCATCGACGGGGTATGGGTTTACCTGGCTTGAGCATTAACTGGGGACCATGGGCACAA
GAGGGAATGGCAGCAAATTTGGATAGTCCTCATCAAGATAGAATGGTGTCCAAGGGAATG
ACTTTTTTGTCTTCAGAACAGGGATTGCAGGTTCTAGGACAATTACTCGAACAATCCATA
CCACAAGTAGGAGTCCTACCAATTCAATGGTCAGTGTTCCAAGAGCAATTTAGTTTTGGT
AATCAAATACCATTGCTGTCCCAATTGGTAAAAGAAAGCAAATCACAGCAAAAAGCCCTC
AAAACAAAGACAAAGCACAATGAATTTTTAGAACAGCTAAAAGCTGCTTTACCAAGAGAA
AGAGAAAAGCTTTTGATAATTTACATTAAAGATGAAATTTCTCAAGTACTTTCTTTGAGC
ACTTCTCAAATTGATATGCAACAGCCCCTGAACACTATGGGGCTTGATTCTCTAATGGCT
GTGGAATTGCACAATAGGCTTCAAACTGACTTGCTCGTGGATATATCTATAGTCAAATTT
ATAGAAGATATCAGTATCGTTGATTTAGCCACTGAAGTGAATGAGCAACTGAGCCAAGTT
GCTCAGAATCAAGGAGTTGAGTCAGAAAATAATGGGCAACTCTACCAAAGCAATAGGAAA
GAAAACGAGCGGATAAGAGGTGAATTATGA
[2] KS45..420
[2] AT579..900
[2] malonyl-CoA774..778
[2] KR1241..1420
[2] ACP1524..1594
[3] KS1619..1998
[3] AT2154..2470
[3] malonyl-CoA2344..2348
[3] DH2518..2688
[3] KR3082..3261
[3] ACP3365..3434
[2] KS133..1260
[2] AT1735..2700
[2] malonyl-CoA2320..2334
[2] KR3721..4260
[2] ACP4570..4782
[3] KS4855..5994
[3] AT6460..7410
[3] malonyl-CoA7030..7044
[3] DH7552..8064
[3] KR9244..9783
[3] ACP10093..10302

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR001227 Acyl transferase domain (Domain)
[571-706] G3DSA:3.40.366.10 [774-889] G3DSA:3.40.366.10 [2147-2276] G3DSA:3.40.366.10 [2344-2459] G3DSA:3.40.366.10
G3DSA:3.40.366.10   Ac_transferase_reg
IPR006162 Phosphopantetheine attachment site (PTM)
[1552-1567] PS00012
PS00012   PHOSPHOPANTETHEINE
IPR009081 Acyl carrier protein-like (Domain)
[1517-1635] 8.20001307135067e-21 SSF47336 [3358-3437] 1.89999859865864e-13 SSF47336
SSF47336   ACP_like
[1527-1593] 8.69999999999999e-11 PF00550 [3369-3432] 2.9e-07 PF00550
PF00550   PP-binding
[1524-1594] PS50075 [3365-3434] PS50075
PS50075   ACP_DOMAIN
[1525-1625] 1.4e-28 G3DSA:1.10.1200.10 [3365-3440] 1.4e-28 G3DSA:1.10.1200.10
G3DSA:1.10.1200.10   ACP_like
IPR013968 Polyketide synthase, KR (Domain)
[1241-1419] 1e-74 PF08659 [3082-3260] 1.60000000000002e-73 PF08659
PF08659   KR
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
[45-295] 5.90000000000008e-98 PF00109 [1619-1873] 1.10000000000001e-94 PF00109
PF00109   ketoacyl-synt
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
[303-420] 1.2e-43 PF02801 [1881-1998] 1.09999999999999e-42 PF02801
PF02801   Ketoacyl-synt_C
IPR014043 Acyl transferase (Domain)
[579-900] 5.30000000000001e-70 PF00698 [2154-2470] 2.39999999999997e-67 PF00698
PF00698   Acyl_transf_1
IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase (Domain)
[577-883] 9.40003071030835e-79 SSF52151 [2149-2464] 6.00001679190159e-77 SSF52151
SSF52151   Acyl_Trfase/lysoPlipase
IPR016036 Malonyl-CoA ACP transacylase, ACP-binding (Domain)
[708-773] 5.39999384454126e-17 SSF55048 [2278-2343] 5.39999384454126e-17 SSF55048
SSF55048   Malonyl_transacylase_ACP-bd
IPR016038 Thiolase-like, subgroup (Domain)
[47-307] G3DSA:3.40.47.10 [308-474] G3DSA:3.40.47.10 [1626-1884] G3DSA:3.40.47.10 [1886-2048] G3DSA:3.40.47.10
G3DSA:3.40.47.10   Thiolase-like_subgr
IPR016039 Thiolase-like (Domain)
[37-473] 2.1000026783403e-98 SSF53901 [1611-2049] 1.3000049540733e-103 SSF53901
SSF53901   Thiolase-like
IPR016040 NAD(P)-binding domain (Domain)
[1240-1456] 7.69999999999997e-90 G3DSA:3.40.50.720 [3083-3294] 1.20000000000001e-99 G3DSA:3.40.50.720
G3DSA:3.40.50.720   NAD(P)-bd
IPR018201 Beta-ketoacyl synthase, active site (Active_site)
[208-224] PS00606 [1786-1802] PS00606
PS00606   B_KETOACYL_SYNTHASE
IPR020801 Polyketide synthase, acyl transferase domain (Domain)
[581-880] SM00827 [2154-2450] 3.00004020669074e-130 SM00827
SM00827   PKS_AT
IPR020806 Polyketide synthase, phosphopantetheine-binding domain (Domain)
[1525-1597] 3.69999438558106e-19 SM00823 [3366-3437] 2.2999993566538e-08 SM00823
SM00823   PKS_PP
IPR020807 Polyketide synthase, dehydratase domain (Domain)
[2518-2688] 5.39999384454126e-25 SM00826
SM00826   PKS_DH
IPR020841 Polyketide synthase, beta-ketoacyl synthase domain (Domain)
[47-473] SM00825 [1621-2049] SM00825
SM00825   PKS_KS
IPR020842 Polyketide synthase/Fatty acid synthase, KR (Domain)
[1241-1420] 5.60004908290974e-65 SM00822 [3082-3261] 2.59998233910302e-66 SM00822
SM00822   PKS_KR
SignalP No significant hit
TMHMM No significant hit
Crypto_00010 Crypto_00010   Crypto_00030 Crypto_00030
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