Crypto_00060 : CDS information

Location

Organism	Nostoc sp.
Strain	ATCC 53789
Entry name	Cryptophycin 1
Contig	EF159954
Start / Stop / Direction	46,916 / 47,800 / + [in whole cluster] 46,916 / 47,800 / + [in contig]
Location	46916..47800 [in whole cluster] 46916..47800 [in contig]
Type	CDS
Length	885 bp (294 aa)

Annotation

Category	5.1 general function
Product	putative oxidoreductase
Product (GenBank)	CrpF
Gene
Gene (GenBank)	crpF
EC number
Keyword
Note
Note (GenBank)	iron containing 2-oxoglutarate dependent oxygenase
Reference	ACC A4D938 PmId [17240975] Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from cyanobionts. (ACS Chem Biol. , 2006) [17240971] Cryptophycin anticancer drugs revisited. (ACS Chem Biol. , 2006) comment [PMID: 17240975](2006) comment in: [PMID: 17240971](2006) cryptophycin生合成遺伝子を同定した論文。 Supplementary Table 1. CrpF: iron-containing 2-oxogluturate dependent oxygenase CrpFに関しての詳細記載なし。
Family/Domain	FD IPR003819 comment [IPR003819] Taurine catabolism dioxygenase TauD/TfdA (Family) function; oxidoreductase activity

Sequence

>putative oxidoreductase [CrpF]
MYSIKIENLIIRVKSVLEMPVSKEAEMANKFNEFGFVILEHEPSATPKNNLLKLSDYFGT
IIQHEHSDSQGIVPISPVDSYPEYVNTTTTDLSLHTDGAFTITPPKVMAMQCQIAAANGG
FTKLIDGKLVYEHLKRTNPVGLLTLFNPDAITVKRDNKKATKPIFEEHHAGLIVRFRADN
AAHVSVESKSFAAFKSFENFVNNPDNQVIFKLAQNQIIIVDNTRVLHGRTAFSKQEYRLL
NRLWFDGQSDIINLKFGISIAPKNLSLFAKKYQPSQIDIGSDISQSTQLKFKAT

>putative oxidoreductase [CrpF]
ATGTATTCAATAAAAATTGAAAATCTAATAATTAGAGTGAAAAGTGTATTAGAAATGCCA
GTTTCTAAAGAAGCTGAGATGGCAAATAAATTTAATGAGTTTGGATTCGTAATACTAGAA
CACGAACCTTCAGCAACACCTAAGAATAACTTATTAAAATTGTCTGATTATTTTGGAACA
ATTATTCAGCACGAACATTCTGATTCACAGGGAATTGTTCCCATCAGTCCTGTTGATAGT
TATCCAGAATATGTAAATACTACAACTACAGATTTATCGTTACATACGGATGGAGCGTTC
ACAATTACTCCACCAAAAGTAATGGCAATGCAGTGCCAGATTGCTGCTGCAAATGGCGGG
TTCACCAAGCTTATTGATGGCAAGCTGGTATATGAACATCTAAAGCGGACAAACCCAGTT
GGATTGTTAACTTTGTTTAATCCTGATGCGATTACAGTCAAAAGAGATAATAAAAAAGCA
ACTAAACCTATTTTTGAAGAACATCATGCTGGGCTTATTGTAAGGTTTAGAGCAGATAAT
GCAGCTCATGTTTCGGTTGAATCGAAAAGTTTTGCGGCATTTAAATCATTTGAAAACTTT
GTAAATAATCCTGACAATCAAGTAATTTTTAAACTTGCACAAAACCAAATAATTATTGTA
GATAATACTAGAGTTTTGCATGGAAGAACTGCATTTTCCAAACAAGAGTATAGGCTACTA
AATCGACTTTGGTTTGATGGACAATCTGATATTATAAATTTAAAGTTTGGTATTTCTATA
GCCCCAAAAAACTTGAGTTTATTTGCTAAAAAGTATCAGCCATCTCAAATAGATATAGGC
TCAGATATTTCTCAGTCAACTCAATTGAAATTTAAAGCCACATGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR003819 Taurine catabolism dioxygenase TauD/TfdA (Family) PF02668 TauD
SignalP	No significant hit
TMHMM	No significant hit

Crypto_00050 Crypto_00070