Rifam_00380 Rifam_00380   Rifam_00400 Rifam_00400

Rifam_00390 : CDS information

close this sectionLocation

Organism
StrainS699
Entry nameRifamycin
Contig
Start / Stop / Direction81,235 / 80,735 / - [in whole cluster]
81,235 / 80,735 / - [in contig]
Locationcomplement(80735..81235) [in whole cluster]
complement(80735..81235) [in contig]
TypeCDS
Length501 bp (166 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category5.2 function unknown
Productpyridoxamine 5'-phosphate oxidase-like FMN-binding domain protein
Product (GenBank)hypothetical protein
Gene
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)
  • ORF3
Reference
ACC
PmId
[9512878] Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699. (Chem Biol. , 1998)
[16079331] Identification of tailoring genes involved in the modification of the polyketide backbone of rifamycin B by Amycolatopsis mediterranei S699. (Microbiology. , 2005)
comment
[PMID: 9512878](1998)
ansamycin系抗生物質rifamycinの生合成gene clusterの報告。
Orf3(166aa): unknown
tableのみ、本文記載なし

---
[PMID: 16079331](2005)
Orf3 Knock-out mutantの表現型パターンはwildと変わらないが、wildより約40%多いrifamycin Bを産生することから、Orf3はrifamycin B産生の調節に関与することが示唆される。
Family/Domain
FD
IPR011576
comment
[IPR011576] Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain (Domain)
function; pyridoxamine-phosphate oxidase activity, FMN binding

close this sectionSequence

selected fasta
>pyridoxamine 5'-phosphate oxidase-like FMN-binding domain protein [hypothetical protein]
MDLSMTEKEEQEFLAGKHIGVLAVHRRSGPPLAVPMWYGYSPGGDVLLWTDGEDTLKGRL
IKKNGAFTLVVQNEDPPYRYVSVSGPVTAWEEATVEAAYSVASRYLPERQAREFVEAFNA
GHVIIRMTPDRWRSVDYGKTSNVLTDREGTRLREHVQTARRGRGRD
selected fasta
>pyridoxamine 5'-phosphate oxidase-like FMN-binding domain protein [hypothetical protein]
GTGGACCTGAGCATGACCGAGAAGGAAGAGCAGGAGTTCCTGGCCGGCAAGCACATCGGC
GTGCTGGCGGTGCACCGGCGAAGCGGCCCGCCGCTGGCGGTACCGATGTGGTACGGCTAC
TCCCCCGGCGGCGACGTGCTGTTGTGGACCGACGGCGAGGACACCTTGAAGGGCAGGCTG
ATCAAGAAGAACGGCGCCTTCACCTTGGTGGTCCAGAACGAGGATCCGCCCTACCGGTAC
GTTTCCGTGTCGGGTCCGGTGACGGCGTGGGAAGAAGCCACCGTCGAGGCCGCGTATTCG
GTGGCGTCGCGGTACCTGCCAGAGCGGCAGGCGCGGGAGTTCGTCGAGGCGTTCAACGCG
GGCCACGTGATCATCCGGATGACGCCGGACCGCTGGCGCAGCGTCGACTACGGCAAGACG
TCGAACGTCCTCACCGACCGCGAAGGGACCCGGCTGCGGGAACACGTGCAGACGGCCCGG
CGCGGGCGCGGGCGCGACTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR009002 FMN-binding split barrel-related (Domain)
[5-134] 7.7e-24 SSF50475
SSF50475   FMN-binding split barrel
IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain (Domain)
[8-93] 1.4e-12 PF01243
PF01243   Pyridox_oxidase
IPR012349 FMN-binding split barrel (Domain)
[5-140] 4.3e-18 G3DSA:2.30.110.10
G3DSA:2.30.110.10   no description
SignalP No significant hit
TMHMM No significant hit
Rifam_00380 Rifam_00380   Rifam_00400 Rifam_00400
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