Rubra_00180 : CDS information

Location

Organism	Streptomyces achromogenes var. rubradiris
Strain	NRRL 3061 (=NBRC 14000)
Entry name	Rubradirin
Contig	AJ871581
Start / Stop / Direction	34,709 / 33,777 / - [in whole cluster] 34,709 / 33,777 / - [in contig]
Location	complement(33777..34709) [in whole cluster] complement(33777..34709) [in contig]
Type	CDS
Length	933 bp (310 aa)

Annotation

Category	5.2 function unknown
Product	glycosyltransferase family protein
Product (GenBank)	putative glycosyltransferase
Gene
Gene (GenBank)	rubG1
EC number
Keyword
Note
Note (GenBank)
Reference	ACC Q2PC72 PmId [18080113] Biosynthesis of rubradirin as an ansamycin antibiotic from Streptomyces achromogenes var. rubradiris NRRL3061. (Arch Microbiol. , 2008) comment Rubradirin生合成clusterの報告。 table1>配列比較からのProposed function RubG1(310aa): Glycosyltransferase 2つのglycosyltransferase analogues RubG1 and G2がrub gene clusterで検出された。RubG2はmutantが作成されて実験的に機能が確かめられているが、RubG1はされておらず詳細不明。
Family/Domain	FD IPR004276 comment [IPR004276] Glycosyl transferase, family 28 (Domain) Function: transferase activity, transferring hexosyl groups

Sequence

>glycosyltransferase family protein [putative glycosyltransferase]
MRFLFTTFAWSSHYYPMVPLGWALQAAGHEVRVATTPSLVDAVVTTGLPAVAVGKDIDIV
GRAGSGKLHDHERWPTDRDKVSCAEDRPSAWIDPCPPSMRVPGQTTAPRLPVRYVPYNAP
GALPAWLIEPPTRPRVCITWGISTVRMIGDAVTGPLSRVVEAVSALGVDVVLAVSAATRA
ALGTVPDGVRVAESLPLHLLLPSCRAIVHQGGVGTALTAGVYAVPQLTVTQFSDQMAVGD
VLAAGGAGRHLLHDEATVERITSHVLGLLDDQECLQAAKLLQREIVSQPAPAALVPRLVQ
LAGLRASPRA

>glycosyltransferase family protein [putative glycosyltransferase]
ATGAGATTCCTGTTCACCACGTTCGCGTGGTCGTCGCACTACTACCCGATGGTGCCGCTC
GGGTGGGCGTTGCAGGCCGCTGGGCATGAGGTACGAGTAGCGACCACGCCGTCGCTGGTC
GACGCGGTCGTCACGACGGGACTGCCGGCGGTGGCGGTGGGCAAGGACATCGACATCGTG
GGCAGGGCCGGGTCCGGCAAGCTGCACGATCATGAACGGTGGCCGACCGATCGAGACAAG
GTGAGTTGCGCCGAGGACCGCCCGTCGGCGTGGATCGACCCCTGCCCGCCCAGCATGCGC
GTCCCCGGACAGACCACGGCCCCGCGGCTGCCCGTCCGGTATGTGCCTTACAACGCCCCC
GGTGCGCTGCCGGCATGGCTCATCGAGCCGCCGACTCGGCCTCGCGTGTGCATCACCTGG
GGCATCTCGACAGTGCGGATGATCGGTGACGCGGTGACCGGTCCGCTGAGCCGGGTCGTC
GAGGCGGTCTCCGCCCTCGGTGTGGATGTCGTGCTCGCCGTCTCCGCAGCCACTCGAGCG
GCTCTTGGCACGGTGCCGGACGGAGTGCGGGTGGCGGAGTCGCTGCCCCTGCACCTGCTG
CTGCCGAGCTGCCGGGCCATCGTGCACCAAGGCGGGGTGGGCACCGCGCTCACCGCAGGC
GTCTACGCGGTGCCCCAACTGACGGTCACCCAGTTCTCCGACCAGATGGCGGTCGGCGAC
GTACTCGCGGCCGGCGGTGCCGGCCGGCATCTCCTCCACGACGAGGCCACCGTGGAGCGG
ATCACGTCCCACGTCCTCGGGCTGCTGGACGACCAGGAGTGCCTCCAAGCCGCCAAGCTC
CTGCAACGGGAGATCGTCTCGCAGCCCGCGCCGGCCGCCTTGGTGCCGAGACTGGTGCAG
CTGGCGGGCCTGCGTGCGTCACCCCGGGCGTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR004276 Glycosyl transferase, family 28 (Domain) PF03033 Glyco_transf_28 IPR010610 Domain of unknown function DUF1205 (Domain) PF06722 DUF1205
SignalP	Eukaryota Bacteria, Gram-negative
TMHMM	No significant hit

Rubra_00170 Rubra_00190