Adria_00270
Adria_00280 : CDS information
Location
| Organism | Streptomyces peucetius |
|---|---|
| Strain | ATCC 29050 (=NBRC 100596) |
| Entry name | Doxorubicin |
| Contig | L35560 |
| Start / Stop / Direction | 28,513 / 29,790 / + [in whole cluster] 4,523 / 5,800 / + [in contig] |
| Location | 28513..29790 [in whole cluster] 4523..5800 [in contig] |
| Type | CDS |
| Length | 1,278 bp (425 aa) |
Annotation
| Category | 1.1 PKS |
|---|---|
| Product | polyketide synthase chain length factor subunit |
| Product (GenBank) | daunorubicin-doxorubicin polyketide synthase |
| Gene | |
| Gene (GenBank) | dpsB |
| EC number | |
| Keyword |
|
| Note | |
| Note (GenBank) |
|
| Reference |
PKS/NRPS Module
Sequence
>polyketide synthase chain length factor subunit [daunorubicin-doxorubicin polyketide synthase]
MTGTAARTASSQLHASPAGRRGLRGRAVVTGLGIVAPNGLGVGAYWDAVLNGRNGIGPLR
RFTGDGRLGRLAGEVSDFVPEDHLPKRLLAQTDPMTQYALAAAEWALRESGCSPSSPLEA
GVITASASGGFAFGQRELQNLWSKGPAHVSAYMSFAWFYAVNTGQIAIRHDLRGPVGVVV
AEQAGGLDALAHARRKVRGGAELIVSGAVDSSLCPYGMAAQVKSGRLSGSDNPTAGYLPF
DRRAAGHVPGEGGAILTVEDAERAAERGAKVYGSIAGYGASFDPPPGSGRPSALARAVET
ALADAGLDGSDIAVVFADGAAVPELDAAEAEALASVFGPRRVPVTVPKTLTGRLYSGAGP
LDVATALLALRDEVVPATAHVDPDPDLPLDVVTGRPRSLADARAALLVARGYGGFNSALV
VRGAA
>polyketide synthase chain length factor subunit [daunorubicin-doxorubicin polyketide synthase]
ATGACAGGTACCGCGGCACGGACCGCGTCTTCGCAGCTCCACGCATCGCCCGCGGGCCGA
CGGGGCCTCAGGGGCCGCGCGGTGGTGACGGGTCTCGGGATCGTCGCCCCCAACGGGCTG
GGGGTGGGCGCGTATTGGGACGCCGTCCTGAACGGCCGCAACGGCATCGGACCGCTGCGG
CGGTTCACCGGCGACGGCCGCCTGGGCCGGCTGGCCGGTGAGGTGAGCGACTTCGTCCCC
GAGGACCATCTGCCGAAGCGGCTGCTGGCGCAGACCGATCCGATGACCCAGTACGCGCTG
GCCGCCGCGGAGTGGGCCCTGCGGGAGTCCGGCTGCTCCCCGTCCTCGCCGCTGGAGGCG
GGGGTGATCACGGCCAGCGCGTCCGGCGGCTTCGCCTTCGGCCAGCGGGAGTTGCAGAAT
CTTTGGAGCAAGGGACCGGCCCACGTCAGCGCCTACATGTCGTTCGCCTGGTTCTACGCC
GTCAACACCGGGCAGATCGCCATCCGGCACGATCTGCGCGGCCCGGTCGGCGTGGTGGTG
GCCGAGCAGGCGGGCGGCCTCGACGCCCTCGCCCACGCTCGCCGCAAGGTCCGGGGCGGA
GCCGAGCTGATCGTCTCGGGCGCCGTGGACTCGTCGCTGTGCCCGTACGGCATGGCGGCC
CAGGTGAAGTCCGGCCGGCTGAGCGGCTCGGACAACCCGACAGCCGGGTATCTGCCGTTC
GACCGGCGGGCGGCCGGACATGTGCCCGGCGAGGGAGGCGCGATCCTCACCGTCGAGGAC
GCGGAGCGGGCCGCCGAGCGGGGCGCGAAAGTGTACGGGTCGATCGCCGGGTACGGCGCG
AGCTTCGACCCGCCGCCCGGCTCCGGCCGCCCCTCCGCCCTCGCCCGTGCCGTCGAGACG
GCGCTGGCCGACGCCGGGCTGGACGGCTCCGACATAGCCGTGGTGTTCGCCGACGGCGCG
GCCGTCCCCGAACTGGACGCAGCCGAGGCGGAGGCTCTGGCGTCGGTCTTCGGGCCGCGC
CGGGTCCCGGTGACCGTCCCCAAGACTCTCACCGGCCGGCTGTATTCGGGCGCCGGGCCG
CTGGACGTGGCGACCGCGCTGCTGGCGCTGCGGGACGAGGTGGTCCCGGCGACCGCCCAC
GTCGACCCCGACCCGGACCTGCCGCTCGACGTGGTGACCGGGCGGCCCCGGTCCCTGGCC
GACGCCAGGGCGGCCCTCCTCGTCGCCCGCGGCTACGGGGGCTTCAACAGCGCTCTGGTG
GTCCGGGGGGCGGCGTGA
Feature
| BLASTP Database:UniProtKB:2011_09 |
|
|---|---|
| InterPro Database:interpro:38.0 |
IPR014030 Beta-ketoacyl synthase, N-terminal (Domain)
IPR014031 Beta-ketoacyl synthase, C-terminal (Domain)
IPR016038 Thiolase-like, subgroup (Domain)
IPR016039 Thiolase-like (Domain)
|
| SignalP |  ![[1-43] 0.739 Signal](../../img/R.gif "[1-43] 0.739 Signal"){kind=small} |
| TMHMM | ![[28-50] Transmembrane (i-o)](../../img/C.gif "[28-50] Transmembrane (i-o)"){kind=small} |
![[26-261] 5.49999999999995e-46 PF00109](../../img/H.gif "[26-261] 5.49999999999995e-46 PF00109"){kind=small}
![[26-277] 2.4e-49 G3DSA:3.40.47.10](../../img/X2.gif "[26-277] 2.4e-49 G3DSA:3.40.47.10"){kind=small}
![[24-269] 2.1000026783403e-53 SSF53901](../../img/B.gif "[24-269] 2.1000026783403e-53 SSF53901"){kind=small}
