Alnu_00240 Alnu_00240   Alnu_00260 Alnu_00260

Alnu_00250 : CDS information

close this sectionLocation

Organism
StrainCM020
Entry nameAlnumycin
Contig
Start / Stop / Direction21,851 / 22,351 / + [in whole cluster]
21,851 / 22,351 / + [in contig]
Location21851..22351 [in whole cluster]
21851..22351 [in contig]
TypeCDS
Length501 bp (166 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative MarR family transcriptional regulator
Product (GenBank)AlnR8 MarR family regulator
Gene
Gene (GenBank)alnR8
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[18940666] Characterization of the alnumycin gene cluster reveals unusual gene products for pyran ring formation and dioxan biosynthesis. (Chem Biol. , 2008)
comment
alnumycin gene clusterのクローニング、シークエンス。
aln2-alnT2の領域をS.albusに導入して、alnumycin産生されることを確認している。

AlnR8: MarR family regulator

配列解析からMarR familyのregulatorであると提唱されている。
Family/Domain
FD
IPR000835
comment
[IPR000835] HTH transcriptional regulator, MarR (Family)
function; sequence-specific DNA binding transcription factor activity

close this sectionSequence

selected fasta
>putative MarR family transcriptional regulator [AlnR8 MarR family regulator]
MSSDGRQGAGLSVDNGVRTLLLLMPRVVARTKRTPVPQQLEEYNLAPRHLSLLAYLFFDG
PLAVSELATRLELVPATVSLLVGELNRYGVVDRKEDEADRRRKIVSIAEPYREAVRSWLE
NGVNAWRVALEPLSPAERQTFIDTLRVYERELMGAQERQAVAATAD
selected fasta
>putative MarR family transcriptional regulator [AlnR8 MarR family regulator]
ATGTCAAGCGATGGTCGGCAGGGGGCAGGGCTGAGCGTCGACAACGGGGTCCGGACGCTC
CTGCTCCTCATGCCGCGCGTCGTCGCACGTACCAAACGCACGCCGGTGCCTCAGCAGTTG
GAGGAGTACAACCTCGCTCCGCGCCACCTGTCCCTGCTGGCCTATCTGTTCTTCGACGGG
CCGCTCGCCGTCAGCGAGCTGGCCACCCGGCTGGAGTTGGTCCCGGCCACCGTCAGCCTG
CTCGTCGGGGAGTTGAACCGGTACGGCGTGGTGGACCGCAAGGAGGACGAGGCCGACCGG
CGCCGCAAGATCGTCAGCATCGCCGAGCCGTACCGGGAAGCGGTGCGCAGCTGGCTGGAG
AACGGCGTGAACGCCTGGCGGGTCGCACTCGAACCGCTGAGCCCGGCCGAACGGCAGACG
TTCATCGACACCCTGCGTGTGTACGAGCGGGAGCTCATGGGCGCGCAGGAGCGACAGGCA
GTCGCTGCCACCGCAGACTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR000835 Transcription regulator HTH, MarR-type (Family)
[17-150] PS50995
PS50995   HTH_MARR_2
[38-138] 3.70000251046782e-14 SM00347
SM00347   HTH_MARR
IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain)
[34-150] 1.6e-20 G3DSA:1.10.10.10
G3DSA:1.10.10.10   Wing_hlx_DNA_bd
SignalP
[1-29] 0.377 Signal
Bacteria, Gram-positive   
[1-29] 0.33 Signal
Bacteria, Gram-negative   
[1-29] 0.33 Signal
Eukaryota   
TMHMM No significant hit
Alnu_00240 Alnu_00240   Alnu_00260 Alnu_00260
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