Avil_00190 : CDS information

Location

Organism	Streptomyces viridochromogenes
Strain	Tü57
Entry name	Avilamycin
Contig	AF333038
Start / Stop / Direction	15,012 / 16,442 / + [in whole cluster] 15,012 / 16,442 / + [in contig]
Location	15012..16442 [in whole cluster] 15012..16442 [in contig]
Type	CDS
Length	1,431 bp (476 aa)

Annotation

Category	4.3 transport
Product	putative transporter
Product (GenBank)	putative transporter
Gene
Gene (GenBank)	aviJ
EC number
Keyword
Note
Note (GenBank)	AviJ
Reference	ACC Q93KW8 PmId [11410376] Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tu57 and production of new antibiotics. (Chem Biol. , 2001) comment avilamycin A生合成遺伝子クラスターの報告。 AviJ: Putative Na+/H+ antiporter from Amycolatopsis orientalis [Proposed function:Antibiotic transport] このORFについて機能解析はされていない。
Related Reference	ACC Q6BJU7 PmId [17559408] ( , ) comment Debaryomyces hansenii(Yeast) Putative sodium KHA1_kha1 Debaryomyces hansenii kha1の機能解析アミノ酸配列はNa+/H+ transporterのクラスに属した。また、Na(+)に対して高い耐性を示すが、他のtoxic cationsあるいはstress factorsには耐性を示さないことを確認している。しかし、機能を同定するにはまだ実験が不十分であるとも言っている。現時点ではputative Na+ transporter。
Family/Domain	FD IPR006153 comment [IPR006153] Cation/H+ exchanger (Domain)

Sequence

>putative transporter [putative transporter]
MAEVTSRGTTRVLAVCLLSVLPLLAAALLLWHGTTGKDDASRPGSGSATPGDAPHVEAWR
LLLALAVVVAVARACGALVGRHLGQPRVVGEMISGIVLGPSVLGLVAPGVHDALFPAALH
SYLDLVAQIGLALFMFLIGMEFGDTHHEGAGRTGAAVGIVGVCVSFALGCALGYALYTGY
APDGVGFLPFTLFLGIAMSVTAFPVLARLLMERGMLQSRAGTYAIVGAATADLACWLLLA
GLVALLRGGSPLGVLRTLALTAVFFGVMVVLVRPALRRVLERPERRLPDGGVLTLIIPGV
LLSAVATELIGIHLIFGAFLFGAICPKTAPALADARGKLQELVTAVLLPPFFASVGLKTD
LLQLGRGGGALWVWAGVALLVAVVGKLAGSAAAAALMSVERVDALRIGVLMNCRGLTELV
ILTIGLELGVLTPALFTMLVIVTLCATVMTAPLLDLLDRAEARTAPARTKASSVVR

>putative transporter [putative transporter]
GTGGCGGAGGTGACATCGCGCGGCACCACCCGCGTGCTTGCCGTGTGCCTGCTGTCGGTG
CTGCCGCTGCTGGCCGCGGCCCTGCTGCTGTGGCACGGCACCACGGGCAAGGACGACGCG
TCGCGACCCGGCTCCGGGAGTGCCACGCCGGGGGATGCGCCGCATGTCGAGGCGTGGCGG
TTGCTGCTCGCCCTCGCCGTGGTGGTGGCCGTCGCGCGGGCCTGCGGAGCGCTGGTCGGC
CGGCACTTGGGCCAGCCACGCGTGGTGGGCGAGATGATCTCCGGGATCGTTCTCGGCCCT
TCGGTGCTCGGCCTCGTCGCTCCCGGGGTCCACGACGCCCTCTTCCCCGCCGCCCTCCAC
TCCTACCTCGATCTCGTCGCCCAGATCGGGCTGGCGCTGTTCATGTTCCTGATCGGCATG
GAGTTCGGTGACACCCACCATGAAGGCGCGGGCCGCACCGGGGCCGCCGTGGGAATCGTC
GGCGTCTGCGTGTCGTTCGCCCTCGGCTGTGCTCTGGGATACGCGCTGTACACCGGCTAC
GCCCCGGACGGCGTCGGCTTCCTGCCGTTCACCCTCTTCCTGGGCATCGCCATGAGCGTG
ACCGCCTTCCCCGTGCTGGCGCGGCTGCTGATGGAACGCGGGATGCTCCAGTCCCGGGCG
GGCACCTACGCCATCGTGGGGGCCGCCACCGCCGATCTCGCCTGCTGGCTGCTGCTCGCG
GGTCTCGTCGCCCTGTTGCGCGGCGGTTCGCCCCTGGGCGTGCTGCGCACCCTCGCGCTC
ACCGCGGTCTTCTTCGGCGTCATGGTGGTGCTCGTCCGCCCCGCCTTGCGACGCGTCCTG
GAGCGGCCGGAGCGCCGGCTGCCCGACGGCGGCGTGCTCACACTGATCATCCCCGGCGTC
CTGCTGTCCGCGGTCGCCACCGAGCTCATAGGCATCCATCTCATCTTCGGCGCCTTCCTG
TTCGGCGCCATCTGCCCGAAGACCGCGCCGGCCCTGGCGGACGCCCGCGGCAAACTGCAG
GAACTCGTCACCGCCGTACTGTTGCCGCCGTTCTTCGCCTCGGTCGGCCTGAAGACCGAC
CTGCTGCAACTCGGCCGGGGCGGCGGCGCCCTGTGGGTGTGGGCCGGCGTCGCCCTGCTG
GTGGCCGTCGTCGGCAAACTGGCGGGCAGCGCGGCGGCAGCGGCGCTGATGTCGGTGGAG
CGCGTCGACGCCCTGCGCATCGGCGTGCTCATGAACTGCCGCGGACTGACCGAACTGGTG
ATCCTCACCATCGGGCTCGAACTCGGCGTCCTGACACCCGCGTTGTTCACCATGCTGGTC
ATCGTCACCCTGTGCGCCACCGTCATGACCGCGCCGCTGCTCGACCTGCTCGACCGCGCC
GAGGCGCGCACCGCGCCCGCCCGTACAAAAGCGAGTTCCGTCGTTCGCTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR006153 Cation/H+ exchanger (Domain) PF00999 Na_H_Exchanger
SignalP	Eukaryota Bacteria, Gram-positive Bacteria, Gram-negative
TMHMM	Transmembrane 12

Avil_00180 Avil_00200