Avil_00390 : CDS information

Location

Organism	Streptomyces viridochromogenes
Strain	Tü57
Entry name	Avilamycin
Contig	AF333038
Start / Stop / Direction	37,955 / 38,971 / + [in whole cluster] 37,955 / 38,971 / + [in contig]
Location	37955..38971 [in whole cluster] 37955..38971 [in contig]
Type	CDS
Length	1,017 bp (338 aa)

Annotation

Category	2.3 modification addition of sugar moiety
Product	putative glycosyltransferase
Product (GenBank)	putative glycosyltransferase
Gene
Gene (GenBank)	aviGT3
EC number
Keyword
Note
Note (GenBank)	AviGT3
Reference	ACC Q93KV3 PmId [11410376] Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tu57 and production of new antibiotics. (Chem Biol. , 2001) comment avilamycin A生合成遺伝子クラスターの報告。 AviGT3: Putative rhamnosyltransferase from Pyrococcus abyssi [Proposed function:Biosynthesis of the heptasaccharide chain] このORFについて機能解析はされていない。
Related Reference	ACC Q9RN50 PmId [15294902] ( , ) comment Mycobacterium smegmatis DTDP-Rha:a-D-GlcNAc-diphosphoryl polyprenol, a-3-L-rhamnosyl transferase_wbbL wbbLは大腸菌ではO-antigen生合成に関与するが、 Mycobacteriumではpeptidoglycanへのcell wall polymer mycolyl-arabinogalactanのattachment(mycolyl-arabinogalactan--linker--peptidoglycan のlinker部分)に関与する。E.coliのO-antigen negative mutant(wbbL不活性)を相補することを確認。
Family/Domain	FD IPR001173 comment [IPR001173] Glycosyl transferase, family 2 (Domain)

Sequence

>putative glycosyltransferase [putative glycosyltransferase]
MNSERRPRVVTITVGTNELCWLDRCLGSLLDSDTTGFDLEVCYVDNDSADGSVEHVRATW
PAVTIIRNDRNLGFAGANNVGIRRALESGADYVFLVNPDTWTPPDLVRGLTELAEEWPEY
GIVGPLQYRYDPDSTALDEFNEWTHTALWLGEQHAFAGDGIAHPSPAGLPKGRAPRTLEH
AYVQGSALFARTAMLREIGLLDEVLHTYYEETDLCRRARWAGWRVALHLDLGIQHRGGGG
ATVASTYSRVHMRRNRYYYLFTDVDWHPAKAARLAGRWLVADLMGRSVVGRVPAATGARE
TIEALRWLADRVPTMRSRRRDHRALRARGGRGAAKGAS

>putative glycosyltransferase [putative glycosyltransferase]
ATGAATTCCGAGCGTCGGCCGCGGGTCGTGACGATCACCGTCGGGACCAACGAGCTGTGC
TGGCTGGACCGGTGTCTCGGCTCCTTGCTGGACAGCGACACCACCGGCTTCGACCTGGAG
GTCTGCTACGTCGACAACGACTCGGCGGACGGCAGTGTCGAGCATGTGCGCGCGACCTGG
CCCGCGGTGACGATCATCCGCAACGACCGCAATCTGGGCTTCGCCGGGGCGAACAACGTC
GGCATCCGCCGCGCCCTGGAGTCCGGCGCGGACTACGTGTTCCTCGTCAACCCCGACACC
TGGACGCCGCCCGACCTGGTGCGCGGACTCACCGAACTGGCCGAGGAATGGCCGGAGTAC
GGCATCGTCGGCCCGCTGCAGTACCGCTACGACCCCGACTCCACGGCGCTCGACGAGTTC
AACGAGTGGACGCACACGGCCCTGTGGCTGGGCGAGCAGCACGCCTTCGCCGGCGACGGG
ATCGCCCATCCCTCCCCGGCGGGGCTGCCGAAGGGGCGGGCCCCACGGACGCTGGAGCAC
GCCTATGTGCAGGGTTCGGCGCTCTTCGCCCGGACCGCGATGCTGCGCGAGATCGGGCTG
CTCGACGAGGTGCTGCACACCTACTACGAGGAGACCGACCTGTGCCGCCGGGCCCGCTGG
GCGGGCTGGCGGGTGGCCCTGCACCTGGACCTGGGCATCCAGCACCGGGGCGGCGGCGGG
GCGACCGTGGCCAGCACGTACAGCCGGGTCCACATGCGGCGCAACCGCTACTACTACCTC
TTCACCGACGTCGACTGGCACCCGGCGAAGGCCGCCCGGCTCGCCGGGCGCTGGCTCGTG
GCGGACCTCATGGGCCGCAGCGTCGTCGGCCGCGTCCCGGCCGCGACCGGAGCGCGGGAG
ACCATCGAGGCGCTGCGCTGGCTCGCCGACCGGGTGCCGACCATGCGGTCCCGCCGCCGG
GACCACCGCGCGCTGCGCGCTCGCGGCGGGCGCGGCGCGGCGAAGGGGGCGTCCTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR001173 Glycosyl transferase, family 2 (Domain) PF00535 Glycos_transf_2
SignalP	Eukaryota
TMHMM	No significant hit

Avil_00380 Avil_00400