Avil_00510 : CDS information

Location

Organism	Streptomyces viridochromogenes
Strain	Tü57
Entry name	Avilamycin
Contig	AF333038
Start / Stop / Direction	51,298 / 51,720 / + [in whole cluster] 51,298 / 51,720 / + [in contig]
Location	51298..51720 [in whole cluster] 51298..51720 [in contig]
Type	CDS
Length	423 bp (140 aa)

Annotation

Category	5.4 hypothetical protein
Product	hypothetical protein
Product (GenBank)
Gene	aviZ2
Gene (GenBank)
EC number
Keyword
Note
Note (GenBank)
Reference	PmId [11410376] Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tu57 and production of new antibiotics. (Chem Biol. , 2001) comment avilamycin A生合成遺伝子クラスターの報告。 AviZ2:Putative oxidoreductase from S.lividans [Proposed function:Sugar biosynthesis] AviG1によるメチル化と AviZ1あるいはAviZ2によるketoreductaseにより、C-3 positionがメチル化された2-deoxy-D-evalose moietyの生合成が完了すると推定している。さらに、GDP-D-fucoseへの変換はAviZ1 or　AviZ2 (4-ketoreduction) and AviQ1, AviQ2 or AviQ3(2-epimerization)によって触媒されるかもしれないとも推測している。このORFについて機能解析はされていない。

Sequence

>hypothetical protein
MPSPATRGFSAYSGTKFVLEGLSEGLADEVADFGIKVLIVEPGSFRTSLFETGRAGASTD
SGLYPKVSRTRGFVSGGDGSQPGDPAKAAALILAALEADETPLRLPLGDDGVTAVLGHLD
QVRNDITTWEKRTRATGFDD

>hypothetical protein
ATGCCGAGCCCTGCGACCAGGGGCTTCTCGGCGTACAGCGGAACGAAGTTCGTCCTGGAG
GGCCTGTCCGAGGGGCTCGCGGACGAGGTCGCCGACTTCGGCATCAAGGTGCTGATCGTC
GAGCCGGGTTCCTTCCGCACCTCGCTGTTCGAGACGGGACGGGCCGGGGCCAGCACGGAC
AGCGGCCTGTACCCGAAGGTGAGCCGGACCCGCGGCTTCGTCTCCGGCGGCGACGGCTCC
CAGCCCGGCGACCCGGCGAAGGCGGCGGCGCTGATCCTGGCCGCGCTGGAGGCGGACGAG
ACCCCGCTGCGGCTGCCGTTGGGCGACGACGGGGTCACTGCCGTGCTCGGTCACCTCGAT
CAGGTGCGCAACGACATCACGACGTGGGAGAAGCGGACCAGGGCGACGGGCTTCGACGAC
TGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	IPR016040 NAD(P)-binding domain (Domain) G3DSA:3.40.50.720 no description
SignalP	No significant hit
TMHMM	No significant hit

Avil_00500 Avil_00520