Pyrlo_00130 Pyrlo_00130   Pyrlo_00150 Pyrlo_00150

Pyrlo_00140 : CDS information

close this sectionLocation

Organism
StrainATCC 31673 (=NBRC 14294)
Entry namePyrrolomycin
Contig
Start / Stop / Direction16,639 / 16,121 / - [in whole cluster]
16,639 / 16,121 / - [in contig]
Locationcomplement(16121..16639) [in whole cluster]
complement(16121..16639) [in contig]
TypeCDS
Length519 bp (172 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category5.4 hypothetical protein
Producthypothetical protein
Product (GenBank)hypothetical protein
Gene
Gene (GenBank)pyr14
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[17158935] Cloning and characterization of the pyrrolomycin biosynthetic gene clusters from Actinosporangium vitaminophilum ATCC 31673 and Streptomyces sp. strain UC 11065. (Antimicrob Agents Chemother. , 2007)
comment
pyrrolomycin biosynthetic gene clustersに関する文献。

pyr14(172 a.a.): unknown

pyr14自体のpyrrolomycin生合成における機能の特定には至っていないが、S-isoprenylcysteine residuesをcarboxymethylationするかもしれないようなRemKとの相同性があるとしている。
Related Reference
ACC
Q70DW6
NITE
Resis_00120
PmId
[18533655] Orchestration of discoid polyketide cyclization in the resistomycin pathway. (J Am Chem Soc. , 2008)
comment
Blast 26th, id38%, 2e-07
Streptomyces resistomycificus_remK
RemK protein

remK deletion mutantはresistomycin生合成に影響しなかった。

close this sectionSequence

selected fasta
>hypothetical protein [hypothetical protein]
MVDVRVWRHFRAVLLAPVLMAVVVPLAIWLTAGLRQVEVPAAGRWLALAVGGALVSAGVA
LFLWTNVLFDREGKGTLAIFDPPRRLVVRGPYRHVRNPMITSVIAVLFGEAVMTRSSWLM
LWSLTFLGVNMLFMPLFEEPGLVRRFGEDYMRYRANVPRWLPRVRPWSGPSD
selected fasta
>hypothetical protein [hypothetical protein]
GTGGTTGACGTGCGGGTGTGGCGACACTTCAGGGCGGTTCTGCTCGCGCCGGTGCTGATG
GCCGTGGTGGTGCCGTTGGCGATCTGGCTCACCGCGGGACTCCGGCAGGTGGAGGTTCCG
GCGGCGGGGCGCTGGTTGGCCCTGGCGGTGGGCGGTGCCCTGGTTTCCGCCGGGGTGGCC
CTCTTCCTGTGGACCAACGTCCTCTTCGACCGCGAGGGCAAGGGCACTTTGGCGATCTTC
GATCCGCCGCGGCGGCTCGTGGTGCGGGGGCCGTACCGTCACGTGCGCAACCCCATGATC
ACTTCGGTGATCGCCGTGCTGTTCGGCGAGGCCGTGATGACCCGGTCGTCGTGGTTGATG
TTGTGGAGTCTGACGTTCCTCGGGGTCAACATGCTCTTCATGCCGCTGTTTGAGGAGCCC
GGACTGGTCCGCCGTTTTGGTGAGGATTACATGCGATACCGAGCGAATGTTCCGCGATGG
CTGCCCCGAGTTCGGCCGTGGTCGGGGCCAAGTGACTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR007318 Phospholipid methyltransferase (Family)
[48-150] 2.9e-16 PF04191
PF04191   PEMT
SignalP
[1-41] 0.722 Signal
Bacteria, Gram-positive   
[1-33] 0.728 Signal
Eukaryota   
TMHMM
[12-31] Transmembrane (i-o) [46-68] Transmembrane (o-i) [118-137] Transmembrane (i-o)
Transmembrane 3   
Pyrlo_00130 Pyrlo_00130   Pyrlo_00150 Pyrlo_00150
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