Pyrlo_00320 Pyrlo_00320   Pyrlo_00340 Pyrlo_00340

Pyrlo_00330 : CDS information

close this sectionLocation

Organism
StrainATCC 31673 (=NBRC 14294)
Entry namePyrrolomycin
Contig
Start / Stop / Direction52,496 / 53,248 / + [in whole cluster]
52,496 / 53,248 / + [in contig]
Location52496..53248 [in whole cluster]
52496..53248 [in contig]
TypeCDS
Length753 bp (250 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative GntR family transcriptional regulator
Product (GenBank)GntR-family regulator
Gene
Gene (GenBank)
EC number
Keyword
Note
  • It is supposed that this ORF is not involved in pyrrolomycin biosynthesis.
Note (GenBank)
  • orf33
Reference
ACC
PmId
[17158935] Cloning and characterization of the pyrrolomycin biosynthetic gene clusters from Actinosporangium vitaminophilum ATCC 31673 and Streptomyces sp. strain UC 11065. (Antimicrob Agents Chemother. , 2007)
comment
pyrrolomycin biosynthetic gene clustersに関する文献。

orf33(250 a.a.): GntR family regulatorory protein

orf33はpyrrolomycin biosynthesisとは関係無いであろうとの記載があるorf32よりも外側に位置しており、orf32同様にpyrrolomycin biosynthesisとは関係無いと予想されている模様。相同性よりGntR family regulatorory proteinと予測。
Family/Domain
FD
IPR000524
comment
[IPR000524] HTH transcriptional regulator, GntR (Domain)

Function
GO:0003700 sequence-specific DNA binding transcription factor activity

close this sectionSequence

selected fasta
>putative GntR family transcriptional regulator [GntR-family regulator]
MTDGTHQPAPITLNRRLPLWYQVSQSLRASVLGRGPDSPLRLPTEEDLARHYGVSVLTVR
QALKPLEEEGLITRHRRRGTFIDPAARPMAPIRLLGSVDAIVAQQSSEEATVLGRGTAAA
PADLAEHFPPGSGTAWFRRLRRHGGEPSSWAENHVLPELGERVRTEDLERWPMTRVLRDR
LGVRISRITDTVQARLADPETAELLGVPLLSPILHYTGVTYDHENQVVDVARIHYRGDRF
SFSVTLEAES
selected fasta
>putative GntR family transcriptional regulator [GntR-family regulator]
GTGACCGACGGCACCCACCAGCCGGCCCCGATCACCCTGAACCGCAGGTTGCCCCTGTGG
TACCAGGTCTCGCAGAGCCTACGGGCCTCCGTCCTCGGCCGCGGCCCGGACAGCCCGCTG
CGGCTGCCGACCGAGGAGGACCTCGCCCGGCACTACGGCGTCAGCGTGCTCACCGTGCGC
CAGGCGTTGAAGCCGTTGGAGGAGGAGGGCCTGATCACCCGGCACCGGCGGCGGGGCACC
TTCATCGACCCCGCCGCCCGCCCCATGGCACCGATACGGCTGCTGGGTTCCGTGGACGCC
ATCGTGGCCCAGCAGTCGAGTGAGGAGGCGACGGTGCTGGGCCGGGGCACCGCCGCGGCC
CCCGCCGACCTGGCCGAGCACTTCCCGCCGGGCTCCGGGACGGCGTGGTTCCGACGGCTG
CGCCGCCACGGCGGGGAGCCGTCGAGCTGGGCGGAGAACCACGTGCTGCCCGAGCTCGGG
GAGCGGGTGCGCACCGAGGACCTGGAACGCTGGCCGATGACCAGGGTGCTGCGGGACCGG
CTCGGGGTGCGGATCAGCCGGATCACCGACACCGTGCAGGCCCGGCTCGCCGACCCGGAG
ACGGCCGAGCTGCTGGGGGTGCCCCTGCTCAGCCCGATCCTGCACTACACCGGGGTGACC
TACGACCACGAGAACCAGGTGGTGGACGTGGCGCGCATCCACTACCGGGGAGACCGCTTC
TCGTTCTCGGTGACCCTGGAGGCGGAGTCCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR000524 Transcription regulator HTH, GntR (Domain)
[42-56] 9.30000048475975e-07 PR00035 [56-72] 9.30000048475975e-07 PR00035
PR00035   HTHGNTR
[23-82] 1.89999859865864e-11 SM00345
SM00345   HTH_GNTR
[17-85] PS50949
PS50949   HTH_GNTR
[40-82] 1.4e-13 PF00392
PF00392   GntR
IPR011663 UbiC transcription regulator-associated (Domain)
[108-240] 1.9e-29 PF07702
PF07702   UTRA
[103-241] 5.69999708783953e-27 SM00866
SM00866   UTRA
IPR011991 Winged helix-turn-helix transcription repressor DNA-binding (Domain)
[15-84] 3.7e-17 G3DSA:1.10.10.10
G3DSA:1.10.10.10   Wing_hlx_DNA_bd
SignalP No significant hit
TMHMM No significant hit
Pyrlo_00320 Pyrlo_00320   Pyrlo_00340 Pyrlo_00340
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