Virg_00100 Virg_00100   Virg_00120 Virg_00120

Virg_00110 : CDS information

close this sectionLocation

Organism
StrainMAFF 10-06014
Entry nameVirginiamycin
Contig
Start / Stop / Direction39,048 / 40,268 / + [in whole cluster]
10,672 / 11,892 / + [in contig]
Location39048..40268 [in whole cluster]
10672..11892 [in contig]
TypeCDS
Length1,221 bp (406 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category5.1 general function
Productputative oxidoreductase
Product (GenBank)Favin-dependent oxidoreductase
Gene
Gene (GenBank)virN
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[17350183] Characterization of biosynthetic gene cluster for the production of virginiamycin M, a streptogramin type A antibiotic, in Streptomyces virginiae. (Gene. , 2007)
[19332826] Hierarchical control of virginiamycin production in Streptomyces virginiae by three pathway-specific regulators: VmsS, VmsT and VmsR. (Microbiology. , 2009)
comment
[PMID:17350183]
virginiamycin M生合成gene clusterの報告。

virginiamycin M1からvirginiamycin M2への変換のためにC26 positionでのhydroxylation and dehydrogenationをVirM and/or VirNが行うかもしれないと推測しているが明らかにはなっていない。

[PMID:19332826]
vms genesの転写解析報告。

virN-virM-vmsS operon
vmsRにより発現が制御される。
Family/Domain
FD
IPR011251

close this sectionSequence

selected fasta
>putative oxidoreductase [Favin-dependent oxidoreductase]
MRPRPPARISFCSPGTFTDHPAPFTHCPRTEPSDGVVMEFGVNFFPVVDPERKTAAEYYA
ESLRLVELAESLGYEHAQIVEHYGSPYGGYSPDPVAFLAAAAARTSRIRLATGAVIAAFT
HPVKLAANLAMLDNLSHGRLDVGFGRAFLPDEFEAFGVPIEESRSRFDDGIAACIALWTE
ENTVFEGAVHRFGPFTGFPRPYQQPHPPVFVASASSPDSCAAAGRAGHHLQVVPSVTTRQ
GLKEMIEGYRQARAEAGHPSGGRIQVKYTCYVSEDRDLALADAREQEQNYVSRMAEAVSS
WAHTRSSQYPGYERFVEKARGYDFDRALTDGKVLAGTPQDVTEQVREIAAEYGSDLCLSL
QFSPGHLPFERAARAMELFALQVAPSFTGRAGAAAGAEAVAVPAAG
selected fasta
>putative oxidoreductase [Favin-dependent oxidoreductase]
ATGCGACCGCGGCCGCCCGCCCGGATATCGTTCTGCTCTCCGGGCACATTCACCGATCAT
CCCGCCCCATTTACTCACTGCCCCCGCACCGAACCTTCGGACGGAGTCGTCATGGAATTC
GGAGTCAATTTCTTCCCGGTCGTGGACCCGGAACGGAAAACTGCCGCCGAGTATTACGCC
GAGAGTCTTCGGCTGGTCGAACTGGCCGAGTCGCTCGGCTATGAACACGCACAGATCGTC
GAGCACTACGGCTCCCCGTACGGCGGCTACAGTCCCGATCCGGTGGCGTTCCTGGCCGCC
GCCGCCGCGCGGACCAGCCGCATCCGGCTCGCGACCGGCGCCGTCATCGCCGCCTTCACC
CACCCCGTCAAGCTCGCCGCCAACCTGGCGATGCTCGACAACCTCTCGCACGGCCGCCTC
GACGTCGGCTTCGGACGGGCCTTCCTGCCCGACGAGTTCGAGGCCTTCGGCGTGCCGATC
GAGGAGAGCCGCTCCCGTTTCGACGACGGCATCGCGGCCTGCATCGCGCTGTGGACCGAG
GAGAACACGGTCTTCGAGGGCGCCGTCCACCGGTTCGGGCCCTTCACCGGCTTCCCCCGC
CCCTACCAGCAGCCCCACCCGCCGGTGTTCGTCGCCTCCGCCAGCAGCCCGGACTCCTGC
GCGGCAGCCGGCCGGGCCGGCCACCACCTCCAGGTCGTACCCTCGGTGACCACCCGTCAG
GGCCTGAAGGAGATGATCGAGGGCTACCGGCAGGCACGCGCCGAGGCCGGGCACCCGAGC
GGCGGGCGGATCCAGGTGAAGTACACCTGCTACGTGTCCGAGGACCGCGATCTGGCGCTG
GCGGACGCCCGCGAGCAGGAGCAGAACTACGTGTCCCGGATGGCCGAGGCGGTCTCGTCC
TGGGCGCACACCCGCAGCAGCCAGTACCCCGGCTACGAGCGGTTCGTGGAGAAGGCCCGC
GGTTACGACTTCGACCGGGCGCTCACCGACGGCAAGGTCCTCGCCGGCACCCCGCAGGAC
GTCACCGAGCAGGTCCGCGAGATCGCCGCCGAGTACGGGTCGGACCTGTGCCTGAGCCTG
CAGTTCAGCCCCGGCCACCTGCCGTTCGAGCGGGCCGCGCGGGCCATGGAGCTGTTCGCC
CTGCAGGTCGCCCCCTCCTTCACCGGCCGGGCCGGTGCGGCCGCCGGGGCGGAGGCCGTC
GCGGTGCCGGCAGCGGGCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR011251 Luciferase-like domain (Domain)
[38-353] 2.80000000000001e-60 PF00296
PF00296   Bac_luciferase
[38-390] 1.79999999999997e-87 G3DSA:3.20.20.30
G3DSA:3.20.20.30   Luciferase_like
[38-391] 3.99998544139406e-76 SSF51679
SSF51679   Luciferase_like
SignalP No significant hit
TMHMM No significant hit
Virg_00100 Virg_00100   Virg_00120 Virg_00120
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