Rever_00160 : CDS information

Location

Organism	Streptomyces sp.
Strain	SN-593
Entry name	Reveromycin
Contig	AB568601
Start / Stop / Direction	44,641 / 43,118 / - [in whole cluster] 44,641 / 43,118 / - [in contig]
Location	complement(43118..44641) [in whole cluster] complement(43118..44641) [in contig]
Type	CDS
Length	1,524 bp (507 aa)

Annotation

Category	5.4 hypothetical protein
Product	hypothetical protein
Product (GenBank)	putative FAD dependent oxidoreductase
Gene
Gene (GenBank)	revH
EC number
Keyword
Note
Note (GenBank)
Reference	ACC G1UDU6 PmId [21642985] Reveromycin A biosynthesis uses RevG and RevJ for stereospecific spiroacetal formation. (Nat Chem Biol. , 2011) comment 配列解析によりrevHのfunctionをMonooxygenaseとしている。また、revE〜revNでPost-PKS modificationとしている。実験情報は無し。

Sequence

>hypothetical protein [putative FAD dependent oxidoreductase]
MAEHVDVLVVGAGLSGIGAAGRLRRADPRRTLAILEARDAVGGTWDLFRYPGVRSDSDMH
TLGYQQRPWKDPKAIADGESILSYIRETAREDGLLDHVRFRHRVVGADWDEAHARWNVRV
ERGAEGEAEEITLTCSFLYLCSGYYRYDEGYSPQFKDADRFGGRIVHPQHWPADLDYTGK
RVVVIGSGATAVTLVPAMAARAAHVTMLQRSPSYVMSLPSRDGIAGALRRVLPERTALAA
IRWKNATLALGFYRFSRKRPEKVKAMLRKGVVKQLPDGYDVDTHFTPRYAPWDQRVCYVP
DGDLFKAISAGEASVVTDHVESFTERGLLLRSGKEVPADVVVTATGLNLLPLGGIRLSVA
GRPVDPGATVAYKGMMLSGVPNFAWTLGYTNSSWTLKADLVAQYVSRLLAHMAERGHAVV
RPLAPPAGDEVLPILDLRSGYVLRGADTMPKRGTRAPWTLEQNYRQDVRLLWRGPVDDAV
EFAPAPSGARAAGSGDAPARPVPETSS

>hypothetical protein [putative FAD dependent oxidoreductase]
GTGGCTGAGCACGTCGATGTCCTCGTCGTCGGGGCGGGACTGTCCGGGATCGGCGCCGCC
GGCCGGTTGCGGCGCGCGGACCCGCGGCGGACGCTGGCGATCCTGGAGGCGCGGGACGCC
GTCGGCGGGACGTGGGACCTGTTCCGGTACCCGGGGGTGCGGTCGGACTCGGACATGCAC
ACCCTGGGCTACCAGCAGCGCCCGTGGAAGGACCCGAAGGCGATCGCCGACGGGGAGAGC
ATCCTGTCCTACATCCGGGAGACCGCCCGGGAGGACGGCCTGCTGGACCACGTCCGCTTC
CGGCACCGGGTGGTCGGCGCGGACTGGGACGAGGCGCACGCCCGCTGGAACGTGCGGGTG
GAGCGGGGCGCGGAGGGCGAGGCCGAGGAGATCACGCTGACCTGCTCCTTCCTCTACCTG
TGCTCGGGCTACTACCGCTACGACGAGGGCTACAGCCCGCAGTTCAAGGACGCCGACCGG
TTCGGGGGGCGGATCGTGCACCCCCAGCACTGGCCCGCGGACCTGGACTACACCGGCAAG
CGCGTCGTCGTCATCGGCAGCGGCGCCACGGCGGTCACCCTGGTGCCCGCGATGGCCGCA
CGGGCCGCGCACGTCACGATGCTCCAGCGCTCGCCCTCCTACGTGATGTCGCTGCCCTCC
CGGGACGGCATCGCGGGCGCGCTGCGCCGGGTGCTGCCCGAGCGCACCGCGCTGGCCGCG
ATCCGGTGGAAGAACGCGACGCTGGCGCTGGGCTTCTACCGGTTCAGCCGCAAGCGCCCC
GAGAAGGTGAAGGCGATGCTGCGCAAGGGCGTCGTCAAGCAGCTCCCGGACGGCTACGAC
GTCGACACCCACTTCACCCCGCGGTACGCGCCGTGGGACCAGCGGGTGTGCTACGTGCCG
GACGGGGACCTGTTCAAGGCGATCAGCGCCGGGGAGGCGTCGGTCGTCACCGACCACGTG
GAGTCCTTCACCGAGAGGGGCCTCCTGCTGCGCTCGGGCAAGGAGGTGCCCGCGGACGTG
GTCGTCACGGCGACCGGTCTGAACCTGCTGCCGCTTGGCGGCATCCGGCTGAGCGTGGCC
GGCCGGCCGGTCGACCCGGGCGCGACGGTCGCCTACAAGGGCATGATGCTCTCCGGGGTG
CCGAACTTCGCCTGGACGCTGGGCTACACCAACAGCTCGTGGACGCTGAAGGCCGACCTC
GTCGCGCAGTACGTGTCCCGGCTGCTGGCGCACATGGCCGAGCGCGGCCACGCCGTGGTG
CGGCCGCTGGCCCCGCCGGCCGGGGACGAAGTGCTGCCGATCCTGGACCTGCGGTCCGGC
TACGTGCTGCGCGGCGCGGACACCATGCCGAAGCGGGGCACGCGCGCGCCGTGGACCCTG
GAGCAGAACTACCGGCAGGACGTCCGGCTGCTTTGGCGCGGTCCGGTGGACGACGCCGTG
GAGTTCGCCCCGGCGCCCTCCGGCGCCCGGGCCGCCGGCTCCGGGGACGCCCCGGCGCGT
CCGGTGCCGGAGACGAGTTCCTGA

Feature

BLASTP Database:UniProtKB:2011_09	show BLAST table
InterPro Database:interpro:38.0	No significant hit
SignalP	Eukaryota
TMHMM	No significant hit

Rever_00150 Rever_00170